記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Alcohol Clinical and Experimental Research - 2024 - Miyake - Maternal alcohol consumption during pregnancy and child.pdf

DOI： 10.1111/acer.15487

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Elsevier BV  

DOI： 10.1016/j.jad.2024.06.001

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：WILEY  

添付ファイル： Nursing Forum - 2024 - Saigusa - Effects of Work‐Family Conflict and Work Engagement Interactions on Hospital Nurses .pdf

DOI： 10.1155/2024/5510374

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記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：(一社)日本小児アレルギー学会  

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1371/journal.pone.0306247

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記述言語：日本語   掲載種別：研究論文（その他学術会議資料等）   出版者・発行元：(一社)日本糖尿病学会  

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： J Psychiatr Res 2024 Ohashi Y MMSP of of postpartum depression.pdf

DOI： 10.1016/j.jpsychires.2024.01.033

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： J Dermatol 2024 Kojima R Association between filaggrin gene mutations and the clinical features of molluscum contagiosum.pdf

DOI： 10.1111/1346-8138.17157

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： https://doi.org/10.1016/j.xjon.2023.11.020

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Diabetol Int 2024 Matsuura N Mortality in type 1 diabetes in Japan.pdf

DOI： 10.1007/s13340-023-00688-0

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記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：(一社)日本疫学会  

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記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）  

J-GLOBAL

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記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）  

J-GLOBAL

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： 1-s2.0-S2666273623004175-main.pdf

DOI： 10.1016/j.xjon.2023.11.020

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担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1111/irv.13221

DOI： 10.1111/irv.13221

記述言語：英語   掲載種別：研究論文（学術雑誌）  

OBJECTIVES: High-resolution manometry (HRM) and esophagography are used for achalasia diagnosis; however, achalasia phenotypes combining esophageal motility and morphology are unknown. Moreover, predicting treatment outcomes of per-oral endoscopic myotomy (POEM) in treatment-naïve patients remains an unmet need. METHODS: In this multicenter cohort study, we included 1,824 treatment-naïve patients diagnosed with achalasia. In total, 1,778 patients underwent POEM. Clustering by machine learning (ML) was conducted to identify achalasia phenotypes using patients' demographic data, including age, sex, disease duration, body mass index, and HRM/esophagography findings. ML models were developed to predict persistent symptoms (Eckardt score ≥3) and reflux esophagitis (RE) (Los Angeles grades A to D) after POEM. RESULTS: ML identified three achalasia phenotypes: phenotype 1, type I achalasia with a dilated esophagus (n=676; 37.0%); phenotype 2, type II achalasia with a dilated esophagus (n=203; 11.1%); phenotype 3, late-onset type I-III achalasia with a non-dilated esophagus (n=619, 33.9%). Types I and II achalasia in phenotypes 1 and 2 exhibited different clinical characteristics from those in phenotype 3, implying different pathophysiologies within the same HRM diagnosis. A predictive model for persistent symptoms exhibited an area under the curve (AUC) of 0.70. Pre-POEM Eckardt score ≥6 was the greatest contributing factor for persistent symptoms. The AUC for post-POEM RE was 0.61. CONCLUSION: Achalasia phenotypes combining esophageal motility and morphology indicated multiple disease pathophysiologies. ML helped develop an optimal risk stratification model for persistent symptoms with novel insights into treatment resistance factors.

DOI： 10.1111/den.14714

PubMed

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Elsevier  

The relationship between high body mass index (BMI) >25 kg/m2 and risk for stillbirth in the Japanese population remains unclear. This study aimed to estimate the impact of maternal obesity on the risk of stillbirth in a Japanese population. This prospective cohort study used data from the Japan Environment and Children's Study, which recruited pregnant individuals between 2011 and 2014. A total of 93,772 fetuses were considered eligible for inclusion in this study. Stillbirth (fetal death before or during labor at ≥22 completed weeks of gestation) rates were compared among four pre-pregnancy BMI groups: underweight (<18.5 kg/m2), reference (18.5 to <25.0 kg/m2), overweight (25.0 to <30.0 kg/m2), and obese (≥30.0 kg/m2). The association between pre-pregnancy BMI and the risk of stillbirth was estimated using multiple logistic regression analyses. The overall stillbirth incidence was 0.33% (305/93,722). Compared with the reference group, the risk of stillbirth was significantly higher in the overweight group (adjusted odds ratio [aOR]: 1.55; 95% confidence interval [CI]: 1.08-2.23) and the obese group (aOR: 2.60; 95% CI: 1.59-4.24). The overall incidence of early stillbirth (i.e., <28 weeks) was 0.17% (155/93,722). Similarly, after adjusting for potential confounding factors, the risk of early stillbirth was significantly higher in the obese group (aOR: 4.33; 95% CI: 2.44-7.70). Increased maternal BMI was associated with an increased risk of stillbirth in the Japanese population. Therefore, counselling women planning for pregnancy on the importance of an appropriate pre-pregnancy BMI to minimize the risk of stillbirth is important.

添付ファイル： 1-s2.0-S2211335523002826-main.pdf

DOI： 10.1016/j.pmedr.2023.102391

PubMed

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記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：日本公衆衛生学会  

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担当区分：筆頭著者,　責任著者   記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：日本公衆衛生学会  

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：IWA Publishing  

Abstract

In regions suffering from water scarcity, residents commonly employ several coping strategies such as the use of multiple water sources, water storage and water sharing and borrowing. This study applies a hierarchical linear regression model to investigate the physical (i.e. water source and supply time) and non-physical (i.e. number of families, wealth status, education for household head, house ownership, water treatment and community involvement) factors associated with individual water consumption throughout the Kathmandu Valley, Nepal. During the baseline period (dry season before the 2015 Gorkha earthquake), the average water consumption was 91 litre/capita/day (LPCD) but there was a regional disparity in water consumption, ranging from 16 to 158 LPCD. The statistical analysis indicated that households using many water sources consumed more water regardless of the supply area even in an emergency. In addition, households with many family members used less water per person. During emergencies, households participating in the local community were found to consume more water than households not participating in the community, especially when the water being used was managed by the community.

添付ファイル： washdev0130687.pdf

DOI： 10.2166/washdev.2023.059

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記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：(一社)日本排尿機能学会  

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担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.ypmed.2023.107599

PubMed

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担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：John Wiley & Sons Australia, Ltd  

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Frontiers in Nutrition  

Background

Animal studies have shown that maternal low-fiber diets during pregnancy may impair brain development and function in offspring, but this has not been validated by epidemiological studies. The aim of this study was to investigate the link between maternal dietary fiber intake during pregnancy and neurodevelopmental delay in offspring using a large birth cohort.

Methods

A total of 76,207 mother-infant pairs were analyzed using data from the Japan Environment and Children's Study, a nationwide prospective cohort study. Maternal dietary fiber intake was estimated using the food frequency questionnaire in mid-pregnancy. Maternal dietary fiber intake was adjusted for energy and classified into quintiles. Developmental delay was assessed in five domains using the Japanese version of the Ages and Stages Questionnaire, Third Edition at the age of 3 years. The logistic regression analysis was performed to estimate the odds ratio (OR) and 95% confidence interval (CI) for the link between dietary fiber intake during pregnancy and developmental delay at the age of 3 years.

Results

The lowest intake group of total dietary fiber had a higher risk of delayed communication [adjusted OR (aOR), 1.51; 95% CI, 1.32–1.74], fine motor (aOR, 1.45; 95% CI, 1.32–1.61), problem-solving (aOR, 1.46; 95% CI, 1.32–1.61), and personal-social skills (aOR, 1.30; 95% CI, 1.12–1.50) than did the highest intake group. An analysis that excluded the effects of insufficient folic acid intake during pregnancy also showed a similar trend.

Conclusion

This study showed that maternal dietary fiber deficiency during pregnancy might influence an increased risk of neurodevelopmental delay in offspring.

添付ファイル： fnut-10-1203669.pdf

DOI： 10.3389/fnut.2023.1203669

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：SPRINGER  

Although it remains debatable, exogenous oxytocin, commonly used for labour induction and augmentation, reportedly increases risks of neurodevelopment delay, attention-deficit/hyperactivity disorder, and autism spectrum disorder among children prenatally exposed to exogenous oxytocin. However, only few studies have objectively examined exogenous oxytocin's impact on early childhood development through scoring evaluations. This study investigated the association between exogenous oxytocin exposure and neurodevelopment in 3-year-old children using the Ages and Stages Questionnaires, Third Edition. In this nationwide prospective cohort study, we extracted data from 104,062 foetal records regarding exogenous oxytocin use during labour from the Japan Environment and Children's Study. Participants completed questionnaires throughout the pregnancy and postpartum periods. Outcomes comprised the developmental status less than each cut-off value for the five domains of the Ages and Stages Questionnaire, Third Edition. We conducted multivariable logistic regression analyses on the data of 55,400 children after controlling for confounders. Among the 55,400 included women, 19.0% (n = 10,506) used exogenous oxytocin during labour and 81.0% (n = 44,894) did not. Children exposed to exogenous oxytocin showed no significantly increased risk of developmental delay in any domain (communication: odds ratio [OR] 1.04, 95% confidence interval [CI] 0.92-1.16; gross motor: OR 0.97, 95% CI 0.87-1.08; fine motor: OR 1.00, 95% CI 0.92-1.09; problem-solving: OR 1.02, 95% CI 0.94-1.11; personal-social: OR 0.91, 95% CI 0.80-1.03).Conclusion: Exogenous oxytocin for labour induction did not adversely affect early childhood development. Further studies accounting for the degree of exogenous oxytocin exposure are required to confirm these results.

添付ファイル： s00431-023-05079-w.pdf

DOI： 10.1007/s00431-023-05079-w

Web of Science

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Wiley  

BACKGROUND AND AIM: Absent contractility (AC) and ineffective esophageal motility (IEM) are esophageal hypomotility disorders diagnosed using high-resolution manometry (HRM). Patient characteristics and disease course of these conditions and differential diagnosis between AC and achalasia are yet to be elucidated. METHODS: A multicenter study involving 10 high-volume hospitals was conducted. Starlet HRM findings were compared between AC and achalasia. Patient characteristics including underlying disorders and disease courses were analyzed in AC and IEM. RESULTS: Fifty-three patients with AC and 92 with IEM were diagnosed, while achalasia was diagnosed in 1784 patients using the Chicago classification v3.0 (CCv3.0). The cut-off integrated relaxation pressure (IRP) value at 15.7 mmHg showed maximum sensitivity (0.80) and specificity (0.87) for differential diagnosis of AC from type I achalasia. While most ACs were based on systemic disorders such as scleroderma (34%) and neuromuscular diseases (8%), 23% were sporadic cases. The symptom severity of AC was not higher than that of IEM. Regarding the diagnosis of IEM, the more stringent CCv4.0 excluded 14.1% of IEM patients than the CCv3.0, although patient characteristics did not change. In patients with the hypomotile esophagus, concomitance of reflux esophagitis was associated with low distal contractile integral and IRP values. AC and IEM transferred between each other, paralleling with the underlying disease course, although no transition to achalasia was observed. CONCLUSION: A successful determination of the optimal cut-off IRP value was achieved using the starlet HRM system to differentiate AC and achalasia. Follow-up HRM is also useful for differentiating AC from achalasia. Symptom severity may depend on underlying diseases instead of hypomotility severity.

添付ファイル： J of Gastro and Hepatol - 2023 - Ikebuchi - Clinical characteristics of absent contractility and ineffective esophageal.pdf

DOI： 10.1111/jgh.16268

PubMed

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記述言語：日本語   掲載種別：研究論文（学術雑誌）   出版者・発行元：日本小児泌尿器科学会  

【目的】ヒトは幼児期以降に次第に尿禁制を獲得していくが,胎児期や出生時,そしてその後の成長・発達過程における様々な素因と,尿禁制獲得の時期とを縦断的に調査した報告はない.小児の夜間を含めた尿禁制獲得時期に関与する因子を縦断的コホート研究にて検討した.【方法】対象は2017年度に山梨大学の調査に登録した3歳児のうち,2021年度までの5年間で解析に必要なデータが得られた437例である.質問票により尿禁制獲得に関与すると想定される因子と尿禁制獲得時期を調査し,先行研究から関連があると報告される100近くの項目でlog-rank検定を行い,さらに多変量解析も行った.【結果】log-rank検定では,女児,布オムツの使用,35歳未満での出産,経腟分娩,3歳までの排便の自立,3歳時のASQ-3(幼児の発達を評価する質問票)でのコミュニケーション・粗大運動・問題解決・対人社会性の項がカットオフ値以上の場合などに,有意により早い年齢で尿禁制を獲得する結果となった.多変量解析では,布オムツの使用,3歳までの排便の自立が有意に早期の尿禁制獲得に関与する因子であった.【結論】小児の尿禁制獲得時期に影響する多数の因子を検討した初の縦断的調査である.諸家の報告と同様に,排便の自立度が尿禁制獲得に強く関与していたことが,一般集団を対象とした前向き研究からも明らかとなった.(著者抄録)

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.3418/jjam.JJAM-2022-0043

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：ELSEVIER  

添付ファイル： 1-s2.0-S0165032723002458-main.pdf

DOI： 10.1016/j.jad.2023.02.088

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その他リンク： https://www.sciencedirect.com/science/article/pii/S0165032723002458

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1080/14767058.2023.2209251

DOI： 10.1080/14767058.2023.2209251

記述言語：日本語   掲載種別：研究論文（学術雑誌）   出版者・発行元：(一社)日本糖尿病学会  

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.gie.2022.10.039 Get rights and content

DOI： 10.1016/j.gie.2022.10.039 Get rights and content

記述言語：日本語   掲載種別：研究論文（学術雑誌）   出版者・発行元：(一社)日本糖尿病学会  

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記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：(一社)日本糖尿病学会  

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Springer Science and Business Media LLC  

Abstract

Hypertensive disorders of pregnancy (HDP) increase the risk of preterm births and cesarean delivery. This study aimed to investigate whether maternal blood leukocyte, monocyte, or neutrophil counts in the first trimester are related to the development of HDP. Data were collected from the Japan Environment and Children’s Study, a large birth cohort study (n = 38,194) that recruited pregnant women in 15 Regional Centers across Japan (from January 2011 to March 2014). The odds ratios (ORs) for mild/severe HDP according to the cut-off value of leukocyte/neutrophil/monocyte counts by the receiver operating characteristic curve showed high ORs. Furthermore, pregnant women with the highest quartiles of leukocyte and monocyte counts had higher adjusted ORs (aORs) for mild (leukocyte: aOR = 1.27, 95% confidence interval [CI]: 1.02–1.58; monocyte: aOR = 1.30, 95% CI 1.04–1.63) and severe HDP (leukocyte: aOR = 1.51, 95% CI 1.08–2.13; monocyte: aOR = 1.44, 95% CI 1.03–2.01) compared with those with the lowest quartiles of those counts. In addition, pregnant women with the highest neutrophil counts had higher aOR for mild HDP (aOR = 1.26, 95% CI 1.02–1.56) compared with those with the lowest count. In conclusion, high leukocyte and monocyte counts in the first trimester are associated with the development of HDP. Thus, they may be used to predict subsequent HDP.

DOI： 10.22541/au.167915051.14233222/v1

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その他リンク： https://www.nature.com/articles/s41598-024-55623-3

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：NATURE PORTFOLIO  

The association between maternal pre-pregnancy smoking status and asthma risk is unclear. This study aimed to investigate the association between pre- and post-pregnancy maternal smoking status and bronchial asthma at 3 years of age in a large birth cohort. Data of 75,411 mother-child pairs from the Japan Environment and Children's Study (JECS) were analysed using multivariate logistic regression analysis. Overall, 7.2% of the children had bronchial asthma. The maternal smoking status before childbirth was as follows: Never = 60.0%, Quit before recognising current pregnancy = 24.1%, Quit after finding out about current pregnancy = 12.3%, and Still smoking = 3.6%. Children of mothers who sustained smoking during pregnancy had an increased risk of bronchial asthma at 3 years of age even after adjusting for pre- and postnatal covariates (adjusted odds ratio [aOR] 1.34, 95% confidence interval [CI] 1.15-1.56). Children of mothers who quit before (aOR 1.09, 95% CI 1.02-1.18) or after (aOR 1.11, 95% CI 1.01-1.23) recognising the current pregnancy had an increased risk of bronchial asthma at 3 years of age. Maternal smoking throughout pregnancy and smoking exposure pre-pregnancy or in early pregnancy increases the risk of bronchial asthma in children.

添付ファイル： s41598-023-30304-9.pdf

DOI： 10.1038/s41598-023-30304-9

PubMed

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その他リンク： https://www.nature.com/articles/s41598-023-30304-9

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：BMC  

DOI： https://doi.org/10.1186/s12887-023-03878-6

その他リンク： https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-023-03878-6

記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：(一社)日本疫学会  

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記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：(一社)日本疫学会  

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：JAPANESE SOC ALLERGOLOGY  

添付ファイル： Kojima2023 pollinosis.pdf

DOI： 10.1016/j.alit.2023.01.003

PubMed

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その他リンク： https://www.sciencedirect.com/science/article/pii/S1323893023000035

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Wiley  

添付ファイル： Health Science Reports - 2022 - Yui - Appropriate procedures to increase the adherence of children to blood collection A.pdf

DOI： 10.1002/hsr2.1036

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その他リンク： https://onlinelibrary.wiley.com/doi/full/10.1002/hsr2.1036

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：SPRINGERNATURE  

DOI： https://doi.org/10.1038/s41390-022-02435-8

その他リンク： https://www.nature.com/articles/s41390-022-02435-8

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.2188/jea.je20230210

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記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）  

J-GLOBAL

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担当区分：筆頭著者,　責任著者   記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）  

J-GLOBAL

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記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）  

J-GLOBAL

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記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）  

J-GLOBAL

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記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）  

J-GLOBAL

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記述言語：日本語   掲載種別：研究論文（学術雑誌）   出版者・発行元：ワールドプランニング  

その他リンク： https://mol.medicalonline.jp/library/journal/download?GoodsID=aj2rsizd/2022/003311/013&name=1199-1210j&UserID=133.23.3.163

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：MDPI  

添付ファイル： ijerph-19-14796-v2.pdf

DOI： 10.3390/ijerph192214796

PubMed

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その他リンク： https://www.mdpi.com/1660-4601/19/22/14796

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：MOSBY-ELSEVIER  

DOI： 10.1016/j.gie.2022.04.1347

その他リンク： https://www.giejournal.org/article/S0016-5107(22)01666-2/fulltext

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：MOSBY-ELSEVIER  

添付ファイル： 1-s2.0-S0016510722021319-main.pdf

DOI： 10.1016/j.gie.2022.10.039

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その他リンク： https://www.sciencedirect.com/science/article/pii/S0016510722021319

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：KOREAN SOC NEUROGASTROENTEROLOGY & MOTILITY  

Background/Aims: ManoScan and Sandhill high-resolution manometry (HRM) systems are used worldwide; however, the diagnosis of achalasia on the Starlet HRM system is not fully characterized. Furthermore, the impact of calcium channel blockers and nitrites in treating achalasia has not been investigated using HRM. Management of recurrent cases is a priority issue, although few studies have examined patient characteristics. Methods: We conducted a multicenter, large-scale database analysis. First, the diagnosis of treatment-naive achalasia in each HRM system was investigated. Next, patient characteristics were compared between type I-III achalasia, and the impact of patient characteristics, including calcium channel blocker and nitrite use for integrated relaxation pressure (IRP) values, were analyzed. Finally, patient characteristics with recurrent achalasia were elucidated. Results: The frequency of type I achalasia with Starlet was significantly higher than that with ManoScan and Sandhill HRM systems. In achalasia, multivariate analysis identified male sex, advanced age, long disease duration, obesity, type I achalasia, and sigmoid type as risk factors related to normal IRP values (< 26 mmHg). Calcium channel blockers and nitrites use had no significant impact on the IRP values, although achalasia symptoms were indicated to be alleviated. In recurrent cases, the IRP value was significantly lower, and advanced age, long disease duration, and sigmoid type were more common than in treatment-naive patients. Conclusions: We should cautiously interpret the type of achalasia and IRP values in the Starlet HRM system. Symptoms of recurrent cases are related to disease progression rather than IRP values, which should be considered in decision making.

添付ファイル： jnm-28-4-562.pdf

DOI： 10.5056/jnm21254

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その他リンク： https://www.jnmjournal.org/journal/view.html?uid=1797&vmd=Full&

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：GEORG THIEME VERLAG KG  

DOI： 10.1055/a-1753-9801

その他リンク： https://www.thieme-connect.com/products/ejournals/html/10.1055/a-1753-9801

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：WILEY  

DOI： https://doi.org/10.1111/ped.15372

その他リンク： https://onlinelibrary.wiley.com/doi/epdf/10.1111/ped.15372

記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：日本公衆衛生学会  

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：GEORG THIEME VERLAG KG  

添付ファイル： Endoscropy 2022 Shiwaku H Risk factors and longterm course of gastroesophageal reflux.pdf

DOI： 10.1055/a-1778-9730

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記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：日本公衆衛生学会  

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記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：日本公衆衛生学会  

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：GEORG THIEME VERLAG KGGEORG THIEME VERLAG KGGEORG THIEME VERLAG KG  

添付ファイル： a-1876-7554.pdf

DOI： 10.1055/a-1876-7554

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：WILEY  

添付ファイル： J of Diabetes Invest - 2022 - Sekine - Association between maternal gestational diabetes mellitus and high‐sensitivity.pdf

DOI： 10.1111/jdi.13796

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その他リンク： https://onlinelibrary.wiley.com/doi/full/10.1111/jdi.13796

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：BMJ PUBLISHING GROUP  

DOI： http://dx.doi.org/10.1136/oemed-2021-108034

その他リンク： https://oem.bmj.com/content/79/8/521

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：OXFORD UNIV PRESS INC  

DOI： 10.1093/dote/doab086

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担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：PUBLIC LIBRARY SCIENCE  

添付ファイル： PLoS One 2022 Yokomichi H Maternal diabetes and perinatal complications.pdf

DOI： 10.1371/journal.pone.0269610

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その他リンク： https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0269610

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：WILEY  

添付ファイル： Digestive Endoscopy 2021 Sato H Esophageal carcinoma in achalasia patients managed with endoscopic submucosal.pdf

DOI： 10.1111/den.14197

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その他リンク： https://onlinelibrary.wiley.com/doi/10.1111/den.14197

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：WILEY  

DOI： 10.1111/den.14369

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その他リンク： https://onlinelibrary.wiley.com/doi/full/10.1111/den.14369

記述言語：英語  

DOI： 10.1038/s41366-022-01097-0

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Karger Publishers  

DOI： 10.1159/000524854

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その他リンク： https://www.karger.com/Article/Abstract/524854

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：MOSBY-ELSEVIER  

DOI： 10.1016/j.gie.2022.04.1347

その他リンク： https://www.sciencedirect.com/science/article/pii/S0016510722016662

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：PUBLIC LIBRARY SCIENCE  

DOI： 10.1371/journal.pone

その他リンク： https://journals.plos.org/plosone/article/authors?id=10.1371/journal.pone.0268204

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：WILEY  

添付ファイル： Digestive Endoscopy - 2021 - Ominami - Impact of the COVID‐19 pandemic on high‐resolution manometry and peroral endoscopic.pdf

DOI： 10.1111/den.14133

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その他リンク： https://onlinelibrary.wiley.com/doi/10.1111/den.14133

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.5056/jnm21188

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：WILEY  

Aims/Introduction Gestational diabetes mellitus (GDM) is one of the most common complications of pregnancy and is associated with adverse pregnancy outcomes. This study aimed to explore the associations between glycated hemoglobin (HbA1c) levels at the early stage of pregnancy and the GDM risk among non-diabetic women in a nationwide study in Japan. In addition, the relationship between GDM and adverse pregnancy outcomes was also analyzed. Materials and Methods This cohort study (n = 89,799) used data from the Japan Environment and Children's Study. We stratified the participants into four groups according to HbA1c levels at an early stage of pregnancy. We investigated the association of HbA1c at an early stage of pregnancy with the risk of GDM, and of GDM with the risk of some representative adverse pregnancy outcomes, using the multiple logistic regression model with adjustment for potential confounders. Results The adjusted odds ratio for GDM per 0.1 percentage point increase in HbA1c (%) was 1.20. The adjusted odds ratio for developing GDM was significantly increased in women from the HbA1c 5.0-5.4% category. GDM significantly increased the adjusted odds ratio for adverse pregnancy outcomes, such as hypertensive disorders of pregnancy, polyhydramnios and premature birth. Conclusions High-normal HbA1c levels at the early stage of pregnancy are significantly associated with GDM risk in women in Japan. GDM was significantly associated with adverse pregnancy outcomes.

添付ファイル： J of Diabetes Invest - 2021 - Sekine - Association of glycated hemoglobin at an early stage of pregnancy with the risk of.pdf

DOI： 10.1111/jdi.13701

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その他リンク： https://onlinelibrary.wiley.com/doi/full/10.1111/jdi.13701

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：AMER MEDICAL ASSOC  

添付ファイル： JAMA Pediatr 2022 Kushima M Screen time and autism.pdf

DOI： 10.1001/jamapediatrics.2021.5778

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その他リンク： https://jamanetwork.com/journals/jamapediatrics/fullarticle/2788488

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：ELSEVIER SCIENCE INC  

添付ファイル： PIIS2212440321006830.pdf

DOI： 10.1016/j.oooo.2021.10.004

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その他リンク： https://www.oooojournal.net/article/S2212-4403(21)00683-0/fulltext

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：BMC  

添付ファイル： s40795-022-00500-3.pdf

DOI： 10.1186/s40795-022-00500-3

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その他リンク： https://bmcnutr.biomedcentral.com/articles/10.1186/s40795-022-00500-3

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Wiley  

DOI： 10.1111/jgh.15708

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その他リンク： https://onlinelibrary.wiley.com/doi/10.1111/jgh.15708

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：OXFORD UNIV PRESS  

添付ファイル： Int Health Koyayashi Y Drinking water source and diarrhoea.pdf

DOI： 10.1093/inthealth/ihab032

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その他リンク： https://academic.oup.com/inthealth/article/14/2/195/6296858

記述言語：日本語   掲載種別：研究論文（学術雑誌）   出版者・発行元：(一社)日本肥満学会  

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担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：MDPI  

添付ファイル： IJREPH 2022 Yokomichi H et al. Farming household and incidence of atopic dermatitis.pdf

DOI： 10.3390/ijerph19031761

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その他リンク： https://www.mdpi.com/1660-4601/19/3/1761

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：ELSEVIER SCI LTD  

BACKGROUND: We aimed to examine whether the timing of adiposity rebound (AR) could be a predictive index of body size in Japanese adolescents. METHODS: The longitudinal individual data of 1438 Japanese children, including 714 boys and 724 girls born between 2001 and 2007, were obtained from child health check-ups conducted at ages 1.5, 2, 3, and 5 years, and then yearly after the age of 6 years. We examined whether the timing of AR could be used to estimate the body size at 14 years of age. RESULTS: The AR had a normal distribution with a mean occurrence at age 6-7 years. The odds ratio of having obesity at age 14 were 8.32 for boys and 4.81 for girls, whereas boys and girls with later AR at the same age had a relative risk of thinness of 6.27 and 8.14, respectively. The probability that children with an early AR (i.e., <6 years old) would be obese was nearly 40%. Similar to obesity, the probability of thinness at 14 years remained approximately 8% for both sexes. CONCLUSIONS: The findings suggest that early AR could raise the risk of obesity, and AR could later raise the risk of thinness. However, both probabilities of AR timing as predictors of adolescent weight status may only be about 10%-20%. This study cannot clearly determine whether the results were influenced by other factors after controlling for the timing of AR. Future studies that also consider lifestyle and genetic factors are warranted.

添付ファイル： Obes Res Clin Pract 2021 Haga C Adiposity rebound as predictor of adolescent obesity.pdf

DOI： 10.1016/j.orcp.2021.12.003

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その他リンク： https://www.sciencedirect.com/science/article/pii/S1871403X2100154X

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Japan Endocrine Society  

添付ファイル： Endcr J 2022 Yokomichi H et al. Mother's iodine exposure and neonate's hypothyroidism.pdf

DOI： 10.1507/endocrj.EJ21-0168

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その他リンク： https://www.jstage.jst.go.jp/article/endocrj/69/1/69_EJ21-0168/_article/-char/en

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Karger Publishers  

DOI： 10.1159/000519153

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その他リンク： https://www.karger.com/Article/Abstract/519153

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：SPRINGER JAPAN KK  

DOI： https://doi.org/10.1007/s10388-021-00875-5

その他リンク： https://link.springer.com/article/10.1007/s10388-021-00875-5

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：SPRINGER JAPAN KK  

添付ファイル： Esophagus 2022 Sato C Characteristics of patients with esophageal motility disorders.pdf

DOI： 10.1007/s10388-021-00875-5

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その他リンク： https://link.springer.com/article/10.1007/s10388-021-00875-5/fulltext.html

記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）  

J-GLOBAL

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：PUBLIC LIBRARY SCIENCE  

添付ファイル： PLoS One 2021 Horiuchi S COVID-19 vaccine hesitancy in Japan.pdf

DOI： 10.1371/journal.pone.0261121

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その他リンク： https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0261121

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：MDPI  

添付ファイル： ijerph-18-12506-v2.pdf

DOI： 10.3390/ijerph182312506

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その他リンク： https://www.mdpi.com/1660-4601/18/23/12506

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：MDPI  

添付ファイル： ijerph 2021 Ooka T Chemicals during pregnancy and foetal death.pdf

DOI： 10.3390/ijerph182211748

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その他リンク： https://www.mdpi.com/1660-4601/18/22/11748

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Wiley  

添付ファイル： Health Sci. Rep 2021 Horiuchi S Caesarian delivery and respikratory distress of neonatespdf.pdf

DOI： 10.1002/hsr2.421

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その他リンク： https://onlinelibrary.wiley.com/doi/epdf/10.1002/hsr2.421

記述言語：日本語   掲載種別：研究論文（学術雑誌）  

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：ELSEVIER  

添付ファイル： J Hydrol Reg Study 2021 Ito Y Water consumption-associated factors.pdf

DOI： 10.1016/j.ejrh.2021.100928

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その他リンク： https://www.sciencedirect.com/science/article/pii/S2214581821001579

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Wiley  

その他リンク： https://onlinelibrary.wiley.com/doi/full/10.1111/ped.14635

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：JAPAN EPIDEMIOLOGICAL ASSOC  

添付ファイル： J Epidemiol Katsumata Precipitated Kawasaki disease by COVID-19.pdf

DOI： 10.2188/jea.JE20210132

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その他リンク： https://www.jstage.jst.go.jp/article/jea/31/11/31_JE20210132/_article/-char/en

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Oxford University Press  

DOI： 10.1093/ije/dyab168.51510.1093/ije/dyab168.515

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その他リンク： https://academic.oup.com/ije/article/50/Supplement_1/dyab168.515/6361855?login=true

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：SPRINGERNATURE  

DOI： 10.1038/s41366-021-00947-7

その他リンク： https://www.nature.com/articles/s41366-021-00947-7https://www.nature.com/articles/s41366-021-00947-7

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS  

添付ファイル： Text_2021KD4_48.pdf

DOI： 10.1097/BRS.0000000000004021

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その他リンク： https://journals.lww.com/spinejournal/abstract/9000/factors_affecting_pedicle_screw_insertional_torque.93764.aspx

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：PERGAMON-ELSEVIER SCIENCE LTD  

添付ファイル： Addict Behav 2021 Kojima R Internet use and depression.pdf

DOI： 10.1016/j.addbeh.2021.106989

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その他リンク： https://www.sciencedirect.com/science/article/pii/S030646032100174X

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Wiley  

We aimed to determine mortality risk in underweight patients with diabetic nephropathy for microalbuminuria or macroalbuminuria. We analyzed mortality and death‐cause data from BioBank Japan, with baseline years 2003–2007. We analyzed mortality rates from all causes and ischemic heart disease, according to body mass index (<18.5, 18.5–21.9, 22–24.9, and ≥25 kg/m2). Mean (standard deviation) of patients’ age, body mass index, and glycated hemoglobin at enrollment was 61.6 (11.7) years, 25.0 (4.4) kg/m2, and 7.7% (1.5)%, respectively. Hazard ratios of all‐cause and ischemic heart disease mortality were highest (1.79 (p=0.0001) and 2.95 (p=0.027), respectively) in patients with body mass index <18.5 kg/m2, as compared with body mass index 22–24.9 kg/m2. All‐cause mortality risk for body mass index <18.5 kg/m2 was similar to that for current smokers (hazard ratio 1.70, p<0.0001). Underweight could be a predictor of mortality risk in patients with diabetic nephropathy for microalbuminuria or macroalbuminuria.

添付ファイル： JDI 2021 Yokomichi H et al. Underweight mortality risk in diabetic nephropathy.pdf

DOI： 10.1111/jdi.13483

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その他リンク： https://onlinelibrary.wiley.com/doi/10.1111/jdi.13483

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Springer International Publishing  

Purpose
Intranasal insulin administration may improve cognitive function in patients with dementia and may prevent cognitive problems after surgery. Although the metabolic effects of intranasal insulin in non-surgical patients have been studied, its influence on glucose concentration during surgery is unknown.

Methods
We conducted a randomized, double-blind, placebo-contolled trial in patients scheduled for elective cardiac surgery. Patients with type 2 diabetes mellitus (T2DM) and non-T2DM patients were randomly allocated to one of three groups (normal saline, 40 international units [IU] of intranasal insulin, and 80 IU intranasal insulin). Insulin was given after the induction of general anesthesia. Glucose and plasma insulin concentrations were measured in ten-minute intervals during the first hour and every 30 min thereafter. The primary outcome was the change in glucose concentration 30 min after intranasal insulin administration.

Results
A total of 115 patients were studied, 43 of whom had T2DM. In non-T2DM patients, 40 IU intranasal insulin did not affect glucose concentration, while 80 IU intranasal insulin led to a statistically significant but not clinically important decrease in blood glucose levels (mean difference, 0.4 mMol·L−1; 95% confidence interval, 0.1 to 0.7). In T2DM patients, neither 40 IU nor 80 IU of insulin affected glucose concentration. No hypoglycemia (< 4.0 mMol·L−1) was observed after intranasal insulin administration in any patients. In non-T2DM patients, changes in plasma insulin were similar in the three groups. In T2DM patients, there was an increase in plasma insulin concentrations ten minutes after administration of 80 IU of intranasal insulin compared with saline.

Conclusions
In patients with and without T2DM undergoing elective cardiac surgery, intranasal insulin administration at doses as high as 80 IU did not cause clinically important hypoglycemia.

DOI： 10.1007/s12630-021-01969-5

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その他リンク： https://link.springer.com/article/10.1007/s12630-021-01969-5

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：BMJ Publishing Group  

添付ファイル： BMJ Open 2021 Yokomichi H et al. Birth month and atopic dermatitis.pdf

DOI： 10.1136/bmjopen-2020-047226

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その他リンク： https://bmjopen.bmj.com/content/11/7/e047226.full

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：BMJ Publishing Group  

添付ファイル： BMJ Nutr Prev 2021 Ooka T Random forest predicts type 2diabetes.pdf

DOI： 10.1136/bmjnph-2020-000200

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その他リンク： https://nutrition.bmj.com/content/4/1/140

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：WILEY  

添付ファイル： J Gastroenterol Hepatol 2021 Tanaka S Special type of achalasiapdf.pdf

DOI： 10.1111/jgh.15557

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その他リンク： https://onlinelibrary.wiley.com/doi/10.1111/jgh.15557

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：ACADEMIC PRESS INC ELSEVIER SCIENCE  

添付ファイル： Environ Res 2021 Kojima R Hair dye and allergies at 3 years old JECS.pdf

DOI： 10.1016/j.envres.2021.111530

PubMed

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その他リンク： https://www.sciencedirect.com/science/article/pii/S0013935121008240

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：WILEY  

DOI： 10.1111/ped.14635

その他リンク： https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ped.14635

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Wiley  

添付ファイル： Pediatr Int 2020 Tanaka T Height SDS change in Japan.pdf

DOI： 10.1111/ped.14577

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その他リンク： https://onlinelibrary.wiley.com/doi/10.1111/ped.14577

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS  

添付ファイル： Medicine 2021 Yoshizawa K Point-rating system for oral health.pdf

DOI： 10.1097/MD.0000000000026111

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その他リンク： https://journals.lww.com/md-journal/Fulltext/2021/06040/Association_between_the_point_rating_system_used.41.aspx

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：MDPI  

添付ファイル： Nutrients Ishikawa M 2021 Difference and variance in nutireint intake by age in Japapnese oler adults.pdf

DOI： 10.3390/nu13051431

Web of Science

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その他リンク： https://www.mdpi.com/2072-6643/13/5/1431/htm

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Springer Japan KK  

添付ファイル： J Gastroenterol 2021 Sato H Achalasia and esophageal cancer in Japan.pdf

DOI： 10.1007/s00535-021-01763-6

PubMed

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その他リンク： https://link.springer.com/article/10.1007/s00535-021-01763-6

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：John Wiley & Sons, Ltd.  

添付ファイル： Endocrinol Diabetes Metab 2020 Saito T T1DM incidence in Yamanashi.pdf

DOI： 10.1002/edm2.214

PubMed

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その他リンク： https://onlinelibrary.wiley.com/doi/10.1002/edm2.214

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Frontiers Media SA  

Background: Scientific innovation is often achieved through the intersection of ideas from different fields. However, barriers prevent non-epidemiologists from cultivating interests in epidemiology or undertaking epidemiologic work. In this study, we evaluated changes in the diversity of research topics in an epidemiologic journal over time. We aimed to understand how epidemiologists and non-epidemiologists communicate about epidemiologic data and how this impacts innovation in the field. Methods: We categorized the topics of articles published in the Journal of Epidemiology during the early and late 2010s based on their titles. We calculated the Shannon-Weaver diversity index (H') to measure changes in the diversity of topics addressed by published articles. Results: Comparing 2011-2013 with 2017-2019, there was no significant change in the diversity of article topics (H' = 4.25 and 4.21, respectively) published in the Journal of Epidemiology. Conclusion: To encourage healthcare providers and public administrators to conduct or comment on epidemiologic studies, epidemiologists should present their findings in easily understood language with appropriate and relevant statistical indicators and useful illustrations. Bringing experience from other specialties into epidemiology may yield new findings from epidemiologic data because of the exposure of non-epidemiologists to different values, workplaces, and occupations. Collaboration among professionals from varied backgrounds and with varied occupational experiences may help to promote scientific innovation by broadening perspectives. In addition, a range of professional experiences may enable individuals to solve difficult research questions more easily by themselves.

添付ファイル： Frontiers Public Health 2021 Yokomichi H et al. Innovation in epidemiology.pdf

DOI： 10.3389/fpubh.2021.641882

PubMed

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その他リンク： https://www.frontiersin.org/articles/10.3389/fpubh.2021.641882/full

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：MDPI  

添付ファイル： Int J Environ Pes Public Health 2021 Yamakita M Protocol of GRAPE Study.pdf

DOI： 10.3390/ijerph18073351

PubMed

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その他リンク： https://www.mdpi.com/1660-4601/18/7/3351/htm

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Elsevier Sci Ltd  

We calculated the Poisson-regression-adjusted relative risk (RR) of new influenza infection by vaccination, prior infection, and vaccination after prior infection in a large Japanese birth cohort, using data from ≤89,253 children aged 6 months to 3 years. The effectiveness of risk reduction (1 - RR) by vaccination at ages 1.5-3 years was 21%-31%. The RR of new infection after prior infection vs. no prior infection was 2.58-19.3 at age 1-3 years. An analysis of the 1 - RR data stratified by having at least one senior sibling and/or attending nursery school revealed that vaccination reduced the RR by 22%-40%. The 1 - RR of new infection was 21% in 3-year-old children who were vaccinated after prior infection. All these findings are statistically significant. The results consistently indicate that, regardless of having at least one senior sibling, attending nursery school, and/or being previously infected with influenza, infants and toddlers will benefit from influenza vaccination.

添付ファイル： Vaccine 2021 Yokomichi H et al. Influenza vaccine effectiveness after prior infection.pdf

DOI： 10.1016/j.vaccine.2021.02.044

PubMed

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その他リンク： https://www.sciencedirect.com/science/article/pii/S0264410X21002243

記述言語：日本語   掲載種別：研究論文（学術雑誌）   出版者・発行元：日本小児保健協会  

その他リンク： https://www.jschild.or.jp/research/archive/

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Springer  

Aim
To investigate the association between falls and accelerometer measured physical activity among older people living in cold, snowy regions in Japan.

Findings
A higher moderate-to-vigorous intensity physical activity levels and walking steps were associated with falls on a frozen road.

Message
The risk of falls, especially on frozen roads, increased among active older people living in cold, snowy regions, and environmental factors should be considered when determining prevention strategies.

添付ファイル： Eur Geriatr Med 2020 Kojima R et al. Physical activity and fal on snow.pdf

DOI： 10.1007/s41999-020-00398-9

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その他リンク： https://link.springer.com/article/10.1007/s41999-020-00398-9

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：日本動脈学会  

添付ファイル： J Atheoscler Thromb 2020 Yan H, Niimi M Endothelial lipase function through beta-VLDL catabolism .pdf

DOI： 10.5551/jat.55244

Scopus

PubMed

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その他リンク： https://www.jstage.jst.go.jp/article/jat/28/2/28_55244/_article/-char/en

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：John Wiley & Sons, Ltd.  

Patients with diabetic nephropathy have the highest mortality rates of all causes, cancer, and macrovascular and infectious diseases. The primary cause of death of patients with diabetes with and without all vascular complications was cancer. The cancer mortality rate was similar, regardless of whether vascular complications were present.

添付ファイル： Endocrionol Diab Metab 2020 BBJ T2DM vascular complication and mortality.pdf

DOI： 10.1002/edm2.181

PubMed

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その他リンク： https://onlinelibrary.wiley.com/doi/10.1002/edm2.181

記述言語：英語  

[This corrects the article DOI: 10.1371/journal.pone.0243702.].

DOI： 10.1371/journal.pone.0250191

PubMed

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Public Library Science  

DOI： https://doi.org/10.1371/journal.pone.0243702

その他リンク： https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0243702

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Public Library Science  

添付ファイル： PLoS One 2020 Mochizuki M Increase in height and obesity in Japanese T1DM.pdf

DOI： 10.1371/journal.pone.0242259

PubMed

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その他リンク： https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0242259

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Spandidos Publications  

Despite the importance of oral care in the prevention of aspiration pneumonia, the association between oral hygiene and the prevalence of pneumonia‑causing bacteria has not yet been determined. The present study is a cross‑sectional study aimed at determining the association between the original point‑rating system used during oral examinations (the prompt non‑invasive oral assessment) and the prevalence of pneumonia‑causing bacteria in a population of hospitalized patients with malnutrition. The nutrition support team cared for 61 patients; 6 were excluded as they were not eligible. Bedside analyses were conducted using the point‑rating system. The findings were analyzed to determine the association between the prompt non‑invasive oral assessment and the detection of pneumonia‑causing bacteria. Patients who tested positive for pneumonia‑causing bacteria (n=13) received significantly higher total and hygiene item scores than those who tested negative (n=42) [median (25th, 75th percentile), total score, 6 (4, 7) vs. 3 (1, 5), P=0.02; hygiene score, 2 (1, 3) vs. 1 (0, 2), P=0.02]. In the receiver operating characteristic analysis, a total oral assessment cut‑off score of 4 was identified as optimal for detecting pneumonia‑causing bacteria. Additionally, a multivariable analysis revealed a high odds ratio for the presence of pneumonia‑causing bacteria in patients with poor oral hygiene (odds ratio, 2.09; 95% CI, 1.04 to 4.22). Thus, the present study demonstrates that the prompt non‑invasive oral assessment is a simple and effective tool for detecting pneumonia‑causing bacteria in hospitalized patients.

添付ファイル： Int J Funct Nutr 2020 Yoshizawa K Point rating for oral health and bacterial pneumonia.pdf

DOI： 10.3892/ijfn.2020.8

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その他リンク： https://www.spandidos-publications.com/10.3892/ijfn.2020.8

記述言語：日本語   出版者・発行元：日本公衆衛生学会  

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Lippincott Williams & Wilkins  

Objective: With the advance of medical care, the duration of dependency on nursing care in later life has increased worldwide. There is a question of whether farm work could extend or shorten the dependency duration. We investigated the association between farm work experience and the duration of dependency on nursing support or care in late life.

Methods: We randomly selected 600 adults aged ≥ 65 years, who were independent and not hospitalized, as part of the Yamanashi Healthy–Active Life Expectancy cohort and
followed them for 13 years. We defined the duration of dependency as the time from
reception of long-term care insurance benefits to death, and we adjusted for multiple
covariates.

Results: We analyzed data from 225 adults (139 men and 86 women) who died during the
follow-up period. Ninety-four had received long-term care benefits. Mean age was 79.6
years (standard deviation [SD]: 6.3) in individuals with farm work experience and 80.1
years (SD: 7.2) in individuals without farm work experience. The estimated duration of
dependency on long-term care was 1.3 years (standard error [SE]: 0.4) in individuals
with farm work experience vs. 2.1 years (SE: 0.5) in individuals without farm work
experience (p = .01). The estimated duration of dependency in individuals with farm
work experience and without farm work experience was 0.4 years (SE: 0.5) vs. 1.3
years (SE: 0.6) in men respectively (p = .03) and 1.6 years (SE: 0.9) vs. 2.4 years (SE:
0.9) in women, respectively (p = .16). The sensitivity analysis yielded an estimated
duration of 1.2 years (SE: 0.5) in those with farm work experience and 2.3 years (SE:
0.5) in those without farm work experience (p = .004).

Conclusion: Individuals with farm work experience required less long-term care prior to death, suggesting that agricultural and physical activities promote health. Policymakers
focusing on preventing the need for nursing care in older populations could consider
promoting farming or gardening.

添付ファイル： Medicine 2020 Haruyama K et al. Farm work reduces late life duration.pdf

DOI： 10.1097/MD.0000000000022248

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その他リンク： https://journals.lww.com/md-journal/Fulltext/2020/09180/Farm_working_experience_could_reduce_late_life.69.aspx

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：BMC  

DOI： 10.21203/rs.2.18119/v310.21203/rs.2.18119/v3

その他リンク： https://link.springer.com/article/10.1186/s12891-020-03564-z

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：日本医師会/日本医学会  

添付ファイル： JMA J 2020 Concordance and discordance of BRAF in metastatic vs. primary lesion of melanoma.pdf

DOI： 10.31662/jmaj.2020-0016

PubMed

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：BMC  

Background
Unplanned pregnancy is a public health issue with adverse consequences for maternal and neonatal health. In Japan, the prevalence of unplanned pregnancy was 46.2% in 2002. However, few studies have investigated this topic, and there is little recent data from Japan. We described and examined the prevalence and determinants of unplanned pregnancy among rural women in Japan from 2011 to 2016.

Methods
We used cross-sectional data from a community-based cohort study (Project Koshu). Data were collected from 2011 to 2016 via a self-report questionnaire included in the Maternal and Child Health Handbook of Japan. Pregnancy intention was measured as a binary variable (planned or unplanned). Univariate and multivariate logistic regression analyses were performed to examine factors associated with unplanned pregnancy, with results reported as odds ratios (ORs) and 95% confidence intervals (CIs). We conducted sensitivity analyses with different definitions of pregnancy intention to assess the robustness of the results. The significance level was set at 5%.

Results
Of the 932 participants (mean ± standard deviation age at baseline: 31.3 ± 5.2 years), 382 (41%) pregnancies were reported as unplanned. The multivariate analyses showed that maternal age (+ 1 year: OR = 0.94, 95% CI: 0.92–0.97, p <  0.001), ‘other’ family structure (OR = 2.76, 95% CI: 1.12–6.76, p = 0.03), three or more pregnancies (OR = 2.26, 95% CI: 1.66–3.08, p <  0.001), current smoking (OR = 2.60, 95% CI: 1.26–5.35, p = 0.01), balanced diet (OR = 0.62, 95% CI: 0.47–0.83, p <  0.001) and current depression (OR = 1.63, 95% CI: 1.24–2.16, p <  0.001) were strongly associated with unplanned pregnancy. These associations were consistent across definitions of pregnancy intention, supporting the robustness of our results.

Conclusions
The prevalence of unplanned pregnancy in the study population was high (41%). Risk factors for unplanned pregnancy were age, number of pregnancies, smoking, having a balanced diet and current depression. These results suggest greater efforts are needed to enhance sex education for young people, improve access to family planning services and provide comprehensive health care for high-risk women to help reduce unplanned pregnancies.

添付ファイル： BMC Pregnancy Childbirth 2020 Huynh ST Prevalence of unplanned pregnancy from Project Koshu.pdf

DOI： 10.1186/s12884-020-03088-3

PubMed

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その他リンク： https://bmcpregnancychildbirth.biomedcentral.com/articles/10.1186/s12884-020-03088-3

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS  

添付ファイル： Spine 2020 Oba H et al. Teriparatide vs bisphosphnate for multilevel lumbar interbody fusion.pdf

DOI： 10.1097/BRS.0000000000003426

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その他リンク： https://journals.lww.com/spinejournal/Abstract/publishahead/Weekly_Teriparatide_versus_Bisphosphonate_for_Bone.94335.aspx

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS  

DOI： 10.1097/BSD.0000000000000945

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その他リンク： https://www.ingentaconnect.com/content/wk/clss/2020/00000033/00000004/art00016

担当区分：最終著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：MOSBY-ELSEVIER  

BACKGROUND AND AIMS: Peroral endoscopic myotomy (POEM) is an available treatment modalities for achalasia. The reported efficacy of POEM in the only prospective multicenter study was 82%; however, a retrospective multicenter study in Japan reported a higher efficacy rate of 95%. The aim of this study was to prospectively verify treatment outcomes after POEM at multiple facilities in Japan. METHODS: This was a prospective single-arm trial of POEM for achalasia at 8 facilities in Japan between April 2016 and March 2018 to evaluate its safety and efficacy. Patients were re-evaluated at 3 months and up to 1 year after POEM. RESULTS: Among the 233 patients with achalasia who underwent POEM, procedure-related adverse events occurred in 24 patients (10.3%), none of whom required surgical intervention. In the 207 patients satisfying the inclusion criteria, the efficacy rate of POEM, defined by an Eckardt score ≤3 at 1 year, was 97.4% (95% CI, 95.3%-99.7%). The Eckardt score decreased significantly from 6.6 ± 2.0 preoperatively to 1.1 ± 1.1, 1 year after POEM. Postoperative reflux esophagitis, severe reflux esophagitis, and symptomatic GERD were reported in 54.2%, 5.6%, and 14.7%, respectively, and proton pump inhibitors were administered in 21.1%. CONCLUSIONS: Our prospective multicenter study in Japan showed greater efficacy of POEM for achalasia compared with the results of a previous prospective multicenter study. POEM is safe and highly effective for at least 1 year. (Clinical trial registration number: UMIN 000021550.).

添付ファイル： Gastrointestinal Endoscopy 2020 Shiwaku H et al. Prognosis of achalasia in Japan.pdf

DOI： 10.1016/j.gie.2019.11.020

PubMed

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その他リンク： https://www.giejournal.org/article/S0016-5107(19)32470-8/fulltext

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Springer JAPAN KK  

This case-control study investigated immune thrombocytopenic purpura (ITP) risk following live, inactivated, and simultaneous vaccination, with a focus on infants aged < 2 years. We matched case patients with ITP to one or two control patients with other diseases by institution, hospital visit timing, sex, and age. We calculated McNemar's pairwise odds ratios (ORs [95% confidence interval]) with 114 case-control pairs. The case group had 27 (44%) males and 22 (35%) infants, and the control group included 49 (43%) males and 42 (37%) infants. For all age groups, the McNemar's OR for ITP occurrence was 1.80 (0.54-6.84, p = 0.64) for all vaccines. Among infants, these were 1.50 (0.17-18.0, p = 0.50) for all vaccines, 2.00 (0.29-22.1, p = 0.67) for live vaccines, and 1.00 (0.01-78.5, p = 0.50) for inactivated vaccines. Sex-adjusted common ORs for simultaneous vaccination were 1.52 (0.45-5.21, p = 0.71) for all vaccines, 1.83 (0.44-7.59, p = 0.40) for inactivated vaccines only, and 1.36 (0.29-6.30, p = 0.69) for mixed live and inactivated vaccines. In infants, these were 1.95 (0.44-8.72, p = 0.38), 1.41 (0.29-6.94, p = 0.67) and 2.85 (0.43-18.9, p = 0.28), respectively. These limited data suggest no significant ITP risk following vaccinations or simultaneous vaccination in any age group, including infants.

添付ファイル： Int J Hematol 2020 ITP risk by inactivated and simultaneous vaccinations.pdf

DOI： 10.1007/s12185-020-02866-1

PubMed

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その他リンク： https://link.springer.com/article/10.1007/s12185-020-02866-1

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：AME Publ Co  

添付ファイル： Ann Transl Med 2020 Tominaga K et al. Capsule endoscopy transit time variation.pdf

DOI： 10.21037/atm.2020.02.40

PubMed

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その他リンク： http://atm.amegroups.com/article/view/37251/html

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（大学，研究機関紀要）   出版者・発行元：山梨大学医学会  

その他リンク： https://yamanashi.repo.nii.ac.jp/index.php?action=pages_view_main&active_action=repository_view_main_item_snippet&index_id=206&pn=1&count=20&order=7&lang=japanese&page_id=30&block_id=67

記述言語：英語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：American Public Health Association  

その他リンク： https://apha.confex.com/apha/2019/meetingapp.cgi/Paper/447242

記述言語：日本語   出版者・発行元：(公社)日本小児科学会  

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記述言語：日本語   出版者・発行元：(公社)日本小児科学会  

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担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Wiley  

添付ファイル： J Diabetes Investig 2020 Yokomichi H et al. Dementia risk of underweight in older people JAGES Cohort.pdf

DOI： 10.1111/jdi.13103

Scopus

PubMed

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その他リンク： https://onlinelibrary.wiley.com/doi/10.1111/jdi.13103

記述言語：日本語  

J-GLOBAL

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記述言語：日本語  

J-GLOBAL

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：MDPI  

添付ファイル： Int J Environ Res Public Health 2020 Ooka T et al. Individual and regional characteristics and maternal smoking.pdf

DOI： 10.3390/ijerph17010173

PubMed

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その他リンク： https://www.mdpi.com/1660-4601/17/1/173

担当区分：筆頭著者,　責任著者   記述言語：日本語   掲載種別：研究論文（学術雑誌）   出版者・発行元：厚生労働統計協会  

その他リンク： https://www.hws-kyokai.or.jp/paper/120-2016-02-15-03-07-32/2352-201910-3.html

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Wolters Kluwer  

DOI： 10.1097/BRS.0000000000003086

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その他リンク： https://journals.lww.com/spinejournal/Abstract/publishahead/Predictors_of_Poor_Global_Alignment_and_Proportion.94618.aspx

記述言語：日本語   出版者・発行元：日本公衆衛生学会  

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担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：Springer  

その他リンク： https://link.springer.com/content/pdf/10.1007%2Fs00125-019-4946-6.pdf

記述言語：英語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：Springer  

その他リンク： https://link.springer.com/content/pdf/10.1007%2Fs00125-019-4946-6.pdf

担当区分：筆頭著者,　責任著者   記述言語：日本語   掲載種別：（MISC）総説・解説（学術雑誌）   出版者・発行元：北隆館  

その他リンク： http://hokuryukan-ns.co.jp/cms/book_category/x11/

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Springer Japan KK  

添付ファイル： J Gastroenterol 2019 Sato H achalasia prevalence in Japan.pdf

DOI： 10.1007/s00535-018-01544-8

PubMed

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その他リンク： https://link.springer.com/article/10.1007/s00535-018-01544-8

担当区分：筆頭著者,　責任著者   記述言語：日本語   掲載種別：（MISC）総説・解説（学術雑誌）   出版者・発行元：北隆館  

その他リンク： http://hokuryukan-ns.co.jp/cms/books/bio-clinica-2019%E5%B9%B4-2%E6%9C%88%E5%8F%B7/

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Springer  

添付ファイル： Int J Hematol 2019 Inoue O et al. Soluble CKEC-2 in acute coronary syndrom.pdf

DOI： 10.1007/s12185-019-02680-4

PubMed

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その他リンク： https://link.springer.com/article/10.1007/s12185-019-02680-4

記述言語：日本語   掲載種別：研究論文（学術雑誌）  

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担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：BMJ PUBLISHING GROUP  

添付ファイル： BMJ Open 2019 Yokomichi H et al. Incidence of hospitalisation with influenza in Japan.pdf

DOI： 10.1136/bmjopen-2018-024687

PubMed

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その他リンク： https://bmjopen.bmj.com/content/9/1/e024687.full

担当区分：筆頭著者,　責任著者   記述言語：日本語   掲載種別：（MISC）総説・解説（学術雑誌）   出版者・発行元：北隆館  

その他リンク： http://hokuryukan-ns.co.jp/cms/books/bio-clinica-2019%E5%B9%B4-2%E6%9C%88%E5%8F%B7/

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：BMJ Journals  

DOI： 10.1136/archdischild-2018-314862

Scopus

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その他リンク： https://adc.bmj.com/content/104/1/53

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Baishideng Publishing Group  

添付ファイル： World J Clin Case 2019 Takano S et al. perforation risk factors of ERCP after intestinal reconstruction.pdf

DOI： 10.12998/wjcc.v7.i1.3091

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その他リンク： https://www.wjgnet.com/2307-8960/full/v7/i1/10.htm

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：WILEY  

添付ファイル： Psychiatr Clin Neurosci 2019 Kojima R et al Intenet addiction and related factors.pdf

DOI： 10.1111/pcn.12791

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その他リンク： https://onlinelibrary.wiley.com/doi/10.1111/pcn.12791

記述言語：日本語  

J-GLOBAL

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記述言語：日本語  

J-GLOBAL

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記述言語：日本語   掲載種別：研究論文（その他学術会議資料等）  

J-GLOBAL

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記述言語：日本語   掲載種別：研究論文（学術雑誌）   出版者・発行元：一般財団法人　厚生労働統計協会  

その他リンク： https://www.hws-kyokai.or.jp/publishing/type/magazine/103-magazine-list/2213-koseinoshihyou1810.html

記述言語：日本語   出版者・発行元：日本公衆衛生学会  

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記述言語：日本語   出版者・発行元：日本公衆衛生学会  

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記述言語：日本語   出版者・発行元：日本公衆衛生学会  

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記述言語：日本語   出版者・発行元：日本公衆衛生学会  

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担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Elsevier  

添付ファイル： J Epidemiol 2018 Yokomichi H et al. Great east Japan earthquake and infant growth.pdf

DOI： 10.2188/jea.JE20170006

DOI： 10.2188/jea.JE2017000610.2188/jea.JE20170006

PubMed

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その他リンク： https://www.jstage.jst.go.jp/article/jea/28/5/28_JE20170006/_article/-char/en

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Elsevier  

添付ファイル： J Epidemiol 2018 Nakamura T et al. SES and underweight and obesity in Japanese population NIPPON DATA.pdf

DOI： 10.2188/jea.JE20170249

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その他リンク： https://www.jstage.jst.go.jp/article/jea/28/Supplement_III/28_JE20170249/_article/-char/en

記述言語：日本語   掲載種別：（MISC）研究発表要旨（全国大会，その他学術会議）   出版者・発行元：(公社)日本小児科学会  

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Nature Publishing Group  

DOI： 10.1038/ijo.2017.242

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その他リンク： https://www.nature.com/articles/ijo2017242

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Elsevier  

添付ファイル： Diabetes Res Clin Pract 2018 Ohde S et al. Optimal HbA1c monitoring interval in type 2 diabetes.pdf

DOI： 10.1016/j.diabres.2017.11.013

PubMed

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その他リンク： https://www.sciencedirect.com/science/article/pii/S0168822717305995

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：Springer Nature  

The data indicate that immediately aftermath of the earthquake, the growth of the affected suckling infants were slightly disturbed. The affected suckling infants in Fukushima also represent increased BMI at the age of 42 months and may have potential to show early adiposity rebound. The results highlight the need of medical follow-up to the infants in Fukushima.

その他リンク： https://ijpeonline.biomedcentral.com/articles/10.1186/s13633-017-0054-x

記述言語：英語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：Springer Nature  

Seasonal growth variation in weight and BMI was detected in relatively overweight preschool children during infancy. These findings suggested that we should be careful of summer time weight gain even in infancy for preventing the future obesity.

その他リンク： https://ijpeonline.biomedcentral.com/articles/10.1186/s13633-017-0054-x

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Elsevier  

添付ファイル： J Urology 2018 Mitsui et al.pdf

DOI： 10.1016/j.juro.2017.11.070

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その他リンク： https://www.jurology.com/article/S0022-5347(17)77960-8/abstract

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Elsevier  

添付ファイル： J Epidemiol 2017 Kikuya M et al. Young child body alteration after the Greas East Japan Earthquake.pdf

DOI： 10.1016/j.je.2016.09.012

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その他リンク： https://www.jstage.jst.go.jp/article/jea/27/10/27_JE81/_article/-char/en

記述言語：英語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：Springer  

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：WILEY  

添付ファイル： Pediatr Diabetes 2016 Mochizuki M et al. Secular ttend of glycaemic control improvement in type 1 diabetes.pdf

DOI： 10.1111/pedi.12409

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その他リンク： https://onlinelibrary.wiley.com/doi/full/10.1111/pedi.12409

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Nagoya Univ Sch Med  

添付ファイル： Nagoya J Med 2017 Sugita H et al. Text message and health literacy in type 2 diabetes. RCT.pdf

DOI： 10.18999/nagjms.79.3.313

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その他リンク： https://www.med.nagoya-u.ac.jp/medlib/nagoya_j_med_sci/793.html

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Nature Publishing Group  

添付ファイル： Modern Pathol 2017 Oishi N et al. Molecular alterations in coexisting thyroid papillary and anaplastic carcinomas.pdf

DOI： 10.1038/modpathol.2017.75

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その他リンク： https://www.nature.com/articles/modpathol201775

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：WILEY  

添付ファイル： Pediatr Int Isojima G et al. Prolonged elevated BMI in children after the Great East Japan Earthquake.pdf

DOI： 10.1111/ped.13340

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その他リンク： https://onlinelibrary.wiley.com/doi/full/10.1111/ped.13340

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： BMJ Open 2017 Yokomichi H et al. Weight cycling and type 2 diabetes onset in urban and rural Japan.pdf

DOI： 10.1136/bmjopen-2016-014684

PubMed

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その他リンク： https://bmjopen.bmj.com/content/7/5/e014684

記述言語：日本語   掲載種別：研究論文（学術雑誌）  

その他リンク： https://mol.medicalonline.jp/archive/search?jo=di6mibyo&ye=2017&vo=&issue=suppl

記述言語：日本語   出版者・発行元：(一社)日本糖尿病学会  

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： BMJ Glob Health 2017 Ishikuro M et al. Disease prevalence among nursery school children after the Great East Japan Earthquake.pdf

DOI： 10.1136/bmjgh-2016-000127

PubMed

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その他リンク： https://gh.bmj.com/content/2/2/e000127

記述言語：日本語   掲載種別：（MISC）総説・解説（国際会議プロシーディングズ）   出版者・発行元：東北大学大学  

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：ELSEVIER SCIENCE INC  

Background: The number of patients with diabetes is increasing worldwide. Macrovascular disease, chronic kidney disease, chronic respiratory disease, cancer and smoking frequently accompany type 2 diabetes. Few data are available related to mortality of Asians with diabetes associated with these serious comorbidities. The present study aimed to quantify the excess mortality risks of type 2 diabetic patients with comorbidities.
Methods: We analysed the available records of 30,834 Japanese patients with type 2 diabetes from the BioBank Japan Project between 2003 and 2007. Men and women were followed up for median 8.03 and 8.30 years, respectively. We applied Cox proportional hazard model and Kaplan-Meier estimates for survival curves to evaluate mortality in diabetic patients with or without macrovascular disease, chronic respiratory disease, chronic kidney disease, cancer and smoking.
Results: Adjusted hazard ratios (HRs) for mortality were 1.39 (95% CI, 1.09-1.78) for male sex, 2.01 (95% CI, 1.78-2.26) per 10-year increment of age. Adjusted HRs of primary interest were 1.77 (95% CI, 1.42-2.22), macrovascular disease; 1.58 (95% CI, 1.08-2.31), chronic respiratory disease; 2.03 (95% CI, 1.67-2.47), chronic kidney disease; 1.16 (95% CI, 0.86-1.56), cancer; and 1.74 (95% CI, 1.30-2.31), current smoking.
Conclusions: Diabetic patients with a past or current history of chronic kidney, macrovascular or respiratory diseases or smoking habit have exhibited the highest risk of mortality. Data were limited to those of survivors of comorbidities but we propose the need to improve comorbidities and terminate cigarette smoking for better prognosis in patients with diabetes. (C) 2017 The Authors. Publishing services by Elsevier B.V. on behalf of The Japan Epidemiological Association.

添付ファイル： J Epidemiol 2017 Yokomichi H et al. Survival of complications and commorbidities with type 2 diabetes from BioBank Japan.pdf

DOI： 10.1016/j.je.2016.12.012

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その他リンク： https://www.sciencedirect.com/science/article/pii/S0917504016301113

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： J Epidemiol 2017 Yokomichi H et al. Cholesterol levels in Japanese dyslipidaemic patients in BioBank Japan.pdf

DOI： 10.1016/j.je.2016.12.014

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その他リンク： https://www.sciencedirect.com/science/article/pii/S0917504016301083

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

Background
Statins are the first-line agents used to treat patients with high serum low-density lipoprotein cholesterol levels, thus reducing the risk of death from arterial sclerotic cardiovascular disease; however, little is known about the effects of non-statin pharmacological interventions on mortality as well as about the potential protective effects of statin use against cancer death. This work aimed to compare all-cause and cancer mortality among patients with hyperlipidaemia who did and did not receive statin treatment.

Methods
Between 2003 and 2007 fiscal years, we recruited Japanese patients diagnosed with hyperlipidaemia from 66 hospitals. Patients in our cohort were followed up for a maximum of 12 years to observe the causes of death. Kaplan–Meier estimates from the baseline were used to compare the mortality of patients based on the administered medicine. All-cause mortality were compared among patients with/without administration of statins and other agents; any-organ and colorectal cancer mortality were compared between patients with/without administration of statins.

Results
Our cohort included 41,930 patients with mean ages of 64–66 years and mean body mass indices of 24–25 kg/m2. Patients who received statin monotherapy and were treated with lifestyle modification exhibited nearly identical survival curves, whereas statin use represented a non-significant but potentially protective effect against colorectal cancer-related mortality. The lowest mortality in this cohort was associated with resin monotherapy.

Conclusions
Mortality rate has been similar for patients treated with statin monotherapy and lifestyle modification. Statin monotherapy could potentially reduce any-organ- and colorectal cancer-related mortality.

添付ファイル： J Epidemiol 2017 Yokomichi H et al. Statin use and all-cause and cancer mortality from BioBank Japan.pdf

DOI： 10.1016/j.je.2016.12.011

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その他リンク： https://www.sciencedirect.com/science/article/pii/S0917504016301095

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：ELSEVIER SCIENCE INC  

Background: Evidence of characteristics of Japanese patients with diabetes from a large-scale population is necessary. Few studies have compared glycaemic controls, complications and comorbidities between type 1 and 2 diabetic patients. This paper focuses on illustrating a clinical picture of Japanese diabetic patients and comparing glycaemic control and prognoses between type 1 and 2 diabetes using multiinstitutional data.
Methods: The BioBank Japan Project enrolled adult type 1 and 2 diabetic patients between fiscal years 2003 and 2007. We have presented characteristics, controls of serum glucose, cholesterol and blood pressure, prevalence of complications and comorbidities and survival curves. We have also shown glycaemic controls according to various individual profiles of diabetic patients.
Results: A total of 558 type 1 diabetic patients and 30,834 type 2 diabetic patients participated in this study. The mean glycated haemoglobin A1c was higher in type 1 diabetes than in type 2 diabetes. In the type 1 diabetic patients, the glycated haemoglobin A1c had no consistent trend according to age and body mass index. The Kaplan-Meier estimates represented a longer survival time from baseline with type 1 diabetes than with type 2 diabetes. Compared with type 1 diabetic patients, type 2 diabetic patients had double the prevalence of macrovascular complications.
Conclusions: This work has revealed detailed plasma glucose levels of type 1 and 2 diabetic patients according to age, body mass index, blood pressure, serum cholesterol levels and smoking and drinking habits. Our data have also shown that the prognosis is worse for type 2 diabetes than for type 1 diabetes in Japan. (C) 2017 The Authors. Publishing services by Elsevier B.V. on behalf of The Japan Epidemiological Association.

添付ファイル： J Epidemiol 2017 Yokomichi H et al. Serum glucose and cholesterol and blood pressure level in Japanese type 1 and 2 diabetes.pdf

DOI： 10.1016/j.je.2016.12.013

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その他リンク： https://www.sciencedirect.com/science/article/pii/S0917504016301101

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Nature Publishing Group  

Background: The evacuation and disruption in housing caused by the 2011 Great East Japan Earthquake and following nuclear radiation may have influenced child health in many respects. However, studies regarding longitudinal childhood growth are limited. Therefore, in this study we aimed to explore the influence of the earthquake on longitudinal changes in body mass index in preschool children.

Methods: Participants were children from nursery schools who cooperated with the study in the Iwate, Miyagi and Fukushima prefectures. The exposed group consisted of children who experienced the earthquake during their preschool-age period (4–5 years old). The historical control group included children who were born 2 years earlier than the exposed children in the same prefectures. Trajectories regarding body mass index and prevalence of overweight/obesity were compared between the two groups using multilevel analysis. Differences in the changes in BMI between before and after the earthquake, and proportion of overweight/obesity was compared between the two groups. We also conducted subgroup analysis by defining children with specific personal disaster experiences within the exposed group.

Results: A total of 9722 children were included in the study. Children in the exposed group had higher body mass indices and a higher proportion of overweight after the earthquake than the control group. These differences were more obvious when confined to exposed children with specific personal disaster experiences.

Conclusions: Children’s growth and development-related health issues such as increased BMI after natural disasters should evoke great attention.

添付ファイル： Int J Obes Zheng W 2017 BMI change at the Great East Japan Earthquakte.pdf

DOI： 10.1038/ijo.2017.6

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その他リンク： https://www.nature.com/articles/ijo20176

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.jash.2016.11.003

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その他リンク： https://www.ashjournal.com/article/S1933-1711(16)30566-6/abstract

記述言語：日本語  

J-GLOBAL

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： BMC 2016 Ohde S et al. Optimal diabetes screening on risk stratification.pdf

DOI： 10.1186/s12902-016-0139-1

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その他リンク： https://bmcendocrdisord.biomedcentral.com/articles/10.1186/s12902-016-0139-1

記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）  

その他リンク： https://mol.medicalonline.jp/archive/search?jo=dh6auxol&ye=2016&vo=22&issue=2

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Pediatr Int 2016 Zheng W Pubertal timing and family history of hypertension from Koshu Project.pdf

DOI： 10.1111/ped.12821

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その他リンク： https://onlinelibrary.wiley.com/doi/full/10.1111/ped.12821

記述言語：日本語   掲載種別：研究論文（学術雑誌）  

その他リンク： https://www.jstage.jst.go.jp/article/jhsaiih/19/1/19_24/_article/-char/en

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1136/bmjopen-2015-010978

その他リンク： https://bmjopen.bmj.com/content/6/4/e010978

記述言語：日本語   掲載種別：（MISC）研究発表要旨（全国大会，その他学術会議）   出版者・発行元：(一社)日本糖尿病学会  

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担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：BMJ PUBLISHING GROUP  

Objective The contributions of highly correlated cardiovascular risk factors to intraocular pressure (IOP) are not clear due to underlying confounding problems. The present study aimed to determine which metabolic syndrome parameters contribute to elevating IOP and to what extent.
Design Retrospective cohort study.
Setting A private healthcare centre in Japan.
Participants Individuals who visited a private healthcare centre and underwent comprehensive medical check-ups between April 1999 and March 2009 were included (20007 in the cross-sectional study and 15747 in the longitudinal study).
Primary and secondary outcome measures Changes in IOP were evaluated in terms of ageing and changes in metabolic syndrome parameters. Pearson's correlation coefficients and mixed-effects models were used to examine the relationship of changes in IOP with ageing and changes in metabolic syndrome parameters in cross-sectional and longitudinal studies, respectively.
Results In the cross-sectional study, IOP was negatively correlated with age and positively correlated with waist circumference, high-density lipoprotein cholesterol (HDL-C) levels, triglyceride levels, systolic blood pressure (SBP), diastolic blood pressure (DBP) and fasting plasma glucose (FPG) levels. In the longitudinal multivariate analysis, the associated IOP changes were -0.12 (p&lt;0.0001) mmHg with male sex; -0.59 (p&lt;0.0001) mmHg with 10years of ageing; +0.42 (p&lt;0.0001) mmHg with 1mmol/L increase in HDL-C levels; +0.092 (p&lt;0.0001) mmHg with 1mmol/L increase in triglyceride levels; +0.090 (p&lt;0.0001) mmHg with 10mmHg increase in SBP; +0.085 (p&lt;0.0001) mmHg with 10mmHg increase in DBP; and+0.091 (p&lt;0.0001) mmHg with 1mmol/L increase in FPG levels.
Conclusions Elevation of IOP was related to longitudinal worsening of serum triglyceride levels, blood pressure and FPG and improvement in serum HDL-C levels.

添付ファイル： BMJ Open 2016 Yokomichi H et al. Intraocular pressure and metabolic syndrome. a cross-sectional study from Japan.pdf

DOI： 10.1136/bmjopen-2015-010360

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その他リンク： https://bmjopen.bmj.com/content/6/3/e010360

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Nature Publishing Group  

DOI： 10.1038/ajg.2015.269

その他リンク： https://journals.lww.com/ajg/Fulltext/2015/10001/The_Association_Between_Meteorological_Factors_and.85.aspx

記述言語：日本語   掲載種別：研究論文（国際会議プロシーディングス）  

その他リンク： https://mol.medicalonline.jp/archive/search?jo=dh6auxol&ye=2015&vo=21&nu=2

記述言語：英語   掲載種別：研究論文（国際会議プロシーディングス）   出版者・発行元：Oxford University Press  

添付ファイル： Int J Epiemiol 2015 Yamagata Z et al. Macrosomia as dentary caries risk at 3 years old.pdf

DOI： 10.1093/ije/dyv097.287

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その他リンク： https://academic.oup.com/ije/article/44/suppl_1/i77/2573890

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： J Am Coll Surg 2015 Inoue H et al. Outcomes of per-oral endoscopic myotomy.pdf

DOI： 10.1016/j.jamcollsurg.2015.03.057

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その他リンク： https://www.sciencedirect.com/science/article/pii/S1072751515002793?via%3Dihub

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

その他リンク： http://www.pieronline.jp/content/article/0386-3603/43070/961

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：BIOMED CENTRAL LTD  

Background: Although obesity is a well-studied risk factor for diabetes, there remains an interest in whether "increasing body mass index (BMI)," "high BMI per se," or both are the actual risk factors for diabetes. The present study aimed to retrospectively compare BMI trajectories of individuals with and without diabetes in a case-control design and to assess whether increasing BMI alone would be a risk factor.
Methods: Using comprehensive health check-up data measured over ten years, we conducted a case-control study and graphically drew the trajectories of BMIs among diabetic patients and healthy subjects, based on coefficients in fitted linear mixed-effects models. Patient group was matched with healthy control group at the onset of diabetes with an optimal matching method in a 1:10 ratio. Simple fixed-effects models assessed the differences in increasing BMIs over 10 years between patient and control groups.
Results: At the time of matching, the mean ages in male patients and controls were 59.3 years [standard deviation (SD) = 9.2] and 57.7 years (SD = 11.2), whereas the mean BMIs were 25.0 kg/m(2) (SD = 3.1) and 25.2 kg/m(2) (SD = 2.9), respectively. In female patients and controls, the mean ages were 61.4 years (SD = 7.9) and 60.1 years (SD = 9.6), whereas the mean BMIs were 24.8 kg/m(2) (SD = 3.5) and 24.9 kg/m(2) (SD = 3.4), respectively. The simple fixed-effects models detected no statistical significance for the differences of increasing BMIs between patient and control groups in males (P = 0.19) and females (P = 0.67). Sudden increases in BMI were observed in both male and female patients when compared with BMIs 1 year prior to diabetes onset.
Conclusions: The present study suggested that the pace of increasing BMIs is similar between Japanese diabetic patients and healthy individuals. The increasing BMI was not detected to independently affect the onset of type 2 diabetes.

添付ファイル： BMC Publ Heal 2015 Mano & Yokomichi et al. BMI trajectory and type 2 diabetes onset. a case-control study.pdf

DOI： 10.1186/s12889-015-2073-y

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その他リンク： https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-015-2073-y

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Public Library Science  

Background
Although many studies have discussed health risks in neonates with a low birth weight, few studies have focused on the risks in neonates with a high birth weight. The objective of this study was to determine whether differences in the incidence of dental caries in early childhood are associated with birth weight status.
Methods
A total of 117,175 children born in Okinawa Prefecture, Japan from 1997 to 2007 were included in this study. Medical professionals collected information about birth records, growth and development, parental child-rearing practices and dental health at 3 months, 18 months and 3 years of age. The risk of dental caries among neonates with macrosomia (birth weight &gt;= 4000 g) was compared with that among neonates with normal weight (2500-3999 g). Sensitivity analyses included 'large for gestational age' (LGA, birth weight above the 90th percentile for gestational age), which was relative to 'appropriate for gestational age' (birth weight between 10th and 90th percentiles). Relative risks and relative risk increases were estimated by multivariate Poisson regression.
Results
At 3 years of age, the relative risk increases for dental caries after adjusting for confounding factors were 19% [95% confidence interval (CI), 11%-28%, P &lt; 0.001] for macrosomic neonates and 12% (95% CI, 9%-16%, P &lt; 0.001) for LGA neonates.
Conclusion
Macrosomia and LGA were associated with an increased risk of dental caries in early childhood. Particular attention should be paid to abnormally large neonates.

添付ファイル： Plos One 2015 Yokomichi H et al. Macrosomia as dentary carry risk factor at 3 years old from Japan.pdf

DOI： 10.1371/journal.pone.0133872

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その他リンク： https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0133872

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

その他リンク： http://www.pieronline.jp/content/article/0386-3603/43070/955

記述言語：日本語   掲載種別：研究論文（学術雑誌）  

その他リンク： https://mol.medicalonline.jp/archive/search?jo=co3labor&vo=63&nu=suppl

記述言語：日本語   出版者・発行元：(一社)日本血栓止血学会  

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： doi.org/10.1371/journal.pone.0118538

その他リンク： https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118538

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： J Epidemiol 2015 Zheng W et al. Maternal smoking and infant growth.pdf

DOI： 10.2188/jea.JE20140040

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その他リンク： https://www.jstage.jst.go.jp/article/jea/25/1/25_JE20140040/_article

記述言語：日本語   掲載種別：研究論文（学術雑誌）  

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.2215/CJN.03530708

その他リンク： https://link.springer.com/article/10.1007/s10157-013-0923-4

記述言語：日本語   出版者・発行元：日本保健科学学会  

DOI： 10.24531/jhsaiih.17.Suppl_28_1

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1097/IJG.0b013e3182741c51

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その他リンク： https://journals.lww.com/glaucomajournal/Abstract/2014/03000/Changes_in_Intraocular_Pressure_and_Associated.11.aspx

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： Paediatr Perinat Epidemiol 2014 Zheng W et al. Adolescent growth in Japan from Koshu Project.pdf

DOI： 10.1111/ppe.12116

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その他リンク： https://onlinelibrary.wiley.com/doi/10.1111/ppe.12116

担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：PUBLIC LIBRARY SCIENCE  

Background: Evidence regarding the mortality rate after administration of the pandemic influenza A (H1N1) 2009 vaccine on patients with underlying diseases is currently scarce. We conducted a case-control study in Japan to compare the mortality rates of patients with idiopathic interstitial pneumonia after the vaccines were administered and were not administered.
Methods: Between October 2009 and March 2010, we collected clinical records in Japan and conducted a 1:1 matched case-control study. Patients with idiopathic interstitial pneumonia who died during this period were considered case patients, and those who survived were considered control patients. We determined and compared the proportion of each group that received the pandemic influenza A (H1N1) 2009 vaccine and estimated the odds ratio. Finally, we conducted simulations that compensated for the shortcomings of the study associated with adjusted severity of idiopathic interstitial pneumonia.
Results: The case and control groups each comprised of 75 patients with idiopathic interstitial pneumonia. The proportion of patients who received the pandemic influenza A (H1N1) 2009 vaccine was 30.7% and 38.7% for the case and control groups, respectively. During that winter, the crude conditional odds ratio of mortality was 0.63 (95% confidence interval, 0.25-1.47) and the adjusted conditional odds ratio was 1.18 (95% confidence interval, 0.33-4.49); neither was significant. The simulation study showed more accurate conditional odds ratios of 0.63-0.71.
Conclusions: In our study, we detected no evidence that the influenza A (H1N1) 2009 vaccine increased the mortality rate of patients with idiopathic interstitial pneumonia. The results, however, are limited by the small sample size and low statistical power. A larger-scale study is required.

添付ファイル： Plos One 2014 Yokomichi H et al. Pandemic influenza vaccine and mortality in idiopathic interstitial pneumonia. case-control study.pdf

DOI： 10.1371/journal.pone.0088927

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その他リンク： https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088927

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： J Epidemiol 2014 Suzuki K et al. Maternal smoking cessation and child grwoth.pdf

DOI： 10.2188/jea.JE20130083

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その他リンク： https://www.jstage.jst.go.jp/article/jea/24/1/24_JE20130083/_article

記述言語：日本語   掲載種別：研究論文（学術雑誌）  

記述言語：英語   掲載種別：研究論文（学術雑誌）  

添付ファイル： J Epidemiol 2013 Zheng W et al. Sex difference in height gain and growth rate in Japanese schoolers from Koshu Project.pdf

DOI： 10.2188/jea.JE20120164

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その他リンク： https://www.jstage.jst.go.jp/article/jea/advpub/0/advpub_JE20120164/_article/-char/en

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：The Association for Research in Vision and Ophthalmology  

その他リンク： https://iovs.arvojournals.org/article.aspx?articleid=2148290