Probe electrospray ionization mass spectrometry-based rapid diagnosis of liver tumors 査読 重要な業績

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   37 ( 11 )   2182 - 2188   2022年11月( ISSN：0815-9319  eISSN：1440-1746 )

Association of allele-specific methylation of the ASNS gene with asparaginase sensitivity and prognosis in T-ALL 査読 重要な業績

Koshi Akahane, Shunsuke Kimura, Kunio Miyake, Atsushi Watanabe, Keiko Kagami, Kentaro Yoshimura, Tamao Shinohara, Daisuke Harama, Shin Kasai, Kumiko Goi, Tomoko Kawai, Kenichiro Hata, Nobutaka Kiyokawa, Katsuyoshi Koh, Toshihiko Imamura, Keizo Horibe, A. Thomas Look, Masayoshi Minegishi, Kanji Sugita, Junko Takita, and Takeshi Inukai

Blood Advances   6 ( 1 )   212 - 224   2021年12月( ISSN：2473-9529 )

High-performance Collective Biomarker From Liquid Biopsy For Diagnosis Of Pancreatic Cancer Based On Mass Spectrometry And Machine Learning 査読 重要な業績

T Iwano, K Yoshimura, G Watanabe, R Saito, S Kiritani, H Kawaida, T Moriguchi, T Murata, K Ogata, D Ichikawa, J Arita, K Hasegawa, S Takeda

Journal of Cancer   12 ( 24 )   7477 - 7487   2021年11月( ISSN：1837-9664 )

New strategy for evaluating pancreatic tissue specimens from endoscopic ultrasound-guided fine needle aspiration and surgery 査読 重要な業績

Seiichiro Fukuhara, Eisuke Iwasaki, Tomohiko Iwano, Yujiro Machida, Hiroki Tamagawa, Shintaro Kawasaki, Takashi Seino, Takahiro Yokose, Yutaka Endo, Kentaro Yoshimura, Kazuhiro Kashiwagi, Minoru Kitago, Haruhiko Ogata, Sen Takeda, Takanori Kanai

JGH Open   5 ( 8 )   953 - 958   2021年8月

Diagnostic significance of plasma lipid markers and machine learning-based algorithm for gastric cancer 査読 重要な業績

RYO SAITO, KENTARO YOSHIMURA, KATSUTOSHI SHODA, SHINJI FURUYA, HIDENORI AKAIKE, YOSHIHIKO KAWAGUCHI, TASUKU MURATA, KORETSUGU OGATA, TOMOHIKO IWANO, SEN TAKEDA, DAISUKE ICHIKAWA

Oncology Letters   21 ( 5 )   1 - 8   2021年3月( ISSN：1792-1074  eISSN：1792-1082 )

Prediction of Pathological and Radiological Nature of Glioma by Mass Spectrometry Combined With Machine Learning 査読 重要な業績

Keiko Suzuki, Kentaro Yoshimura, Tomoyuki Kawataki, Mitsuto Hanihara, Sen Takeda, Hiroyuki Kinouchi

Neurosurgery Open   2 ( 1 )   1 - 8   2021年3月(  eISSN：2633-0873 )

A new rapid diagnostic system with ambient mass spectrometry and machine learning for colorectal liver metastasis 査読 重要な業績

Sho Kiritani, Kentaro Yoshimura, Junichi Arita, Takashi Kokudo, Hiroyuki Hakoda, Meguri Tanimoto, Takeaki Ishizawa, Nobuhisa Akamatsu, Junichi Kaneko, Sen Takeda, Kiyoshi Hasegawa

BMC CANCER   21 ( 1 )   1 - 9   2021年3月( ISSN：1471-2407  eISSN：1471-2407 )

Miniaturized String Sampling Probe and Electrospray Extraction/Ionization within the Ion Inlet Tube for Mass Spectrometric Endoscopy 査読 重要な業績

Lee Chuin Chen, Tomohiko Iwano, Satoshi Ninomiya, Takayuki Koike, Yoshihisa Tanaka, Kentaro Yoshimura

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY   21 ( 2 )   606 - 610   2021年2月( ISSN：1044-0305  eISSN：1879-1123 )

Probe Electrospray Ionization (PESI) and Its Modified Versions: Dipping PESI (dPESI), Sheath-Flow PESI (sfPESI) and Adjustable sfPESI (ad-sfPESI) 査読 重要な業績

Kenzo Hiraoka, Osamu Ariyada, Dilshadbek T Usmanov, Lee C Chen, Satoshi Ninomiya, Kentaro Yoshimura, Sen Takeda, Zhang Yu, Mridul K Mandal, Hiroshi Wada, Stephanie Rankin-Turner, Hiroshi Nonami

JOURNAL OF MASS SPECTROMETRY   9 ( 1 )   1 - 21   2020年12月( ISSN：1076-5174  eISSN：2186-5116 )

Rapid automated diagnosis of primary hepatic tumor by mass spectrometry and artificial intelligence 査読 重要な業績

Silvia Giordano, Sen Takeda, Matteo Donadon, Hidekazu Saiki, Laura Brunelli, Roberta Pastorelli, Matteo Cimino, Cristiana Soldani, Barbara Franceschini, Luca Di Tommaso, Ana Lleo, Kentaro Yoshimura, Hiroki Nakajima, Guido Torzilli, Enrico Davoli

LIVER INTERNATIONAL   40 ( 12 )   3117 - 3124   2020年12月( ISSN：1478-3223  eISSN：1478-3231 )

Breast cancer diagnosis based on lipid profiling by probe electrospray ionization mass spectrometry 査読 重要な業績

T Iwano, K Yoshimura, S Inoue, T Odate , K Ogata, S Funatsu, H Tanihata, T Kondo, D Ichikawa, S Takeda

BRITISH JOURNAL OF SURGERY   107 ( 6 )   632 - 635   2020年5月( ISSN：0007-1323 )

Sample Preparation for Probe Electrospray Ionization Mass Spectrometry 査読 重要な業績

Journal of Visualized Experiments   ( 156 )   2020年2月( ISSN：1940-087X )

Lipidome-based rapid diagnostic system with machine learning for detection of tumor areas with activated TGF-β signaling in head and neck cancer 査読 重要な業績

British Journal of Cancer   2020年2月( ISSN：0007-0920 )

Using Probe Electrospray Ionization Mass Spectrometry and Machine Learning for Detecting Pancreatic Cancer with High Performance 査読 重要な業績

American Journal of Translational Research   12 ( 1 )   171 - 179   2020年1月( ISSN：1943-8141 )

Real-time analysis of living animals and rapid screening of human fluid samples using remote sampling electrospray ionization mass spectrometry 査読 重要な業績

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS   172   372 - 378   2019年8月( ISSN：0731-7085 )

Ambient mass spectrometry-based detection system for tumor cells in human blood 査読 重要な業績

Translational Cancer Research   7 ( 3 )   758 - 764   2018年6月( ISSN：2218-676X )

Detection of potential new biomarkers of atherosclerosis by probe electrospray ionization mass spectrometry 査読 重要な業績

Hisashi Johno, Kentaro Yoshimura, Yuki Mori, Tokuhide Kimura, Manabu Niimi, Masaki Yamada, Tetsuo Tanigawa, Jianglin Fan, Sen Takeda

Metabolomics   14 ( 38 )   1 - 11   2018年2月( ISSN：1573-3882 )

Construction of mass spectra database and diagnosis algorithm for head and neck squamous cell carcinoma 査読 重要な業績

Kei Ashizawa, Kentaro Yoshimura, Hisashi Johno, Tomohiro Inou, Ryohei Katoh, Satoshi Funayama, Kaname Sakamoto, Sen Takeda, Keisuke Masuyama, Tomokazu Matsuoka, Hiroki Ishii

Oral Oncoligy   75   111 - 119   2017年12月( ISSN：1368-8375  eISSN：1879-0593 )

Towards Practical Endscopic Mass Spectrometry 査読 重要な業績

Lee Chuin Chen, Kentaro Yoshimura, Satoshi Ninomiya, Sen Takeda, Kenzo Hiraoka,

Mass spectrometry   6 ( S0070 )   1 - 8   2017年8月( ISSN：1076-5174 )

In-vivo Endoscopic Mass Spectrometry using a Moving String Sampling Probe 査読 重要な業績

Lee Chuin Chen, Tsubasa Naito, Satoru Tsutsui, Yuki Yamada, Satoshi Ninomiya, Kentaro Yoshimura, Sen Takeda, Kenzo Hiraoka

Analyst   142 ( 15 )   2735 - 2740   2017年7月( ISSN：0003-2654  eISSN：1364-5528 )

Hepatitis B virus prevents excessive viral production via reduction of cell-death inducing DFF45-like effectors 査読 重要な業績

Jun Yasumoto, Hirotake Kasai, Kentaro Yoshimura, Teruhime Otoguro, Koichi Watashi, Takaji Wakita, Atsuya Yamashita, Tomohisa Tanaka, Sen Takeda, Kohji Moriishi

Journal of General Virology   98 ( 7 )   1762 - 1773   2017年7月( ISSN：0022-1317  eISSN：1465-2099 )

Desorption in Mass Spectrometry 査読 重要な業績

Dilshadbek Tursunbayevich Usmanov, Satoshi Ninomiya, Lee Chuin Chen, Subhrakanti Saha, Mridul Kanti Mandal, Yuji Sakai, Rio Takaishi, Ahsan Habib, Kenzo Hiraoka, Kentaro Yoshimura, Sen Takeda, Hiroshi Wada, Hiroshi Nonami

Mass Spectrometry   6 ( S0059 )   1 - 16   2017年2月( ISSN：1076-5174 )

Secondary Ion Mass Spectrometry Analysis of Renal Cell Carcinoma with Electrospray Droplet Ion Beams 査読 重要な業績

Satoshi Ninomiya ,Kentaro Yoshimura ,Lee Chuin Chen ,Sen Takeda ,Kenzo Hiraoka

Mass Spectrometry   6 ( A0053 )   1 - 6   2017年1月( ISSN：1076-5174 )

温故知新　リアルタイム質量分析法を応用してがんの基礎研究も可能です 重要な業績

竹田　扇,吉村　健太郎

Cancer Board Square   2 ( 3 )   204 - 208   2016年10月( ISSN：21896410 )

Modulation of primary cilia length by melanin-concentrating hormone receptor 1 査読 重要な業績

Akie Hamamoto,Shogo Yamato,Yohei Katoh,Kazuhisa Nakayama,Kentaro Yoshimura (他3名)

Cellular Signalling   28 ( 6 )   572 - 584   2016年6月( ISSN：0898-6568  eISSN：1873-3913 )

Involvement of FKBP6 in hepatitis C virus replication 査読 重要な業績

Hirotake Kasai,Kunihiro Kawakami,Hiromasa Yokoe,Kentaro Yoshimura,Masanori Matsuda,その他15名

Scientific reports   16 ( 5 )   16699 - 16699   2015年11月( ISSN：20452322 )

相反する視座からの新しいがん診断支援装置の試み臨床病理 重要な業績

竹田 扇,吉村 健太郎,田邉 國士

臨床病理   63 ( 9 )   1083 - 1089   2015年9月( ISSN：00471860 )

Untreated and dried sample analysis by solid probe assisted nanoelectrospray ionization mass spectrometry 査読 重要な業績

Mridul Kanti Mandal,Subhrakanti Saha,Zhan Yu,Kentaro Yoshimura,Sen Takeda,Kenzo Hiraoka

Analytical Methods   7 ( 6 )   2630 - 2635   2015年2月( ISSN：17599679  eISSN：1759-9679 )

Development of Non-proximate Probe Electrospray Ionization for Real-Time Analysis of Living Animal 査読 重要な業績

Kentaro Yoshimura,Lee Chuin Chen,Hisashi Johno,Mayutaka Nakajima,Kenzo Hiraoka,Sen Takeda

Mass Spectrometry   3 ( SP3 )   1 - 7   2014年12月( ISSN：2187137X )

Biomolecular analysis and biological tissue diagnostics by electrospray ionization with a metal wire inserted gel-loading tip 査読 重要な業績

Mandal MK,Yoshimura K,Saha S,Yu Z,Takeda S,Hiraoka K.

Analytical Chemistry   86 ( 2 )   987 - 992   2014年1月( ISSN：00032700  eISSN：1520-6882 )

Direct Electrospray Ionization Mass Spectrometric Profiling of Real-World Samples via a Solid Sampling Probe 査読 重要な業績

Zhan Yu,Lee Chuin Chen,Mridul Kanti Mandal,Kentaro Yoshimura,Sen Takeda,Kenzo Hiraoka

Journal of The American Society for Mass Spectrometry   24 ( 10 )   1612 - 1615   2013年10月( ISSN：10440305 )

Real time diagnosis of chemically-induced hepatocellular carcinoma using a novel mass spectrometry-based technique 査読 重要な業績

Kentaro Yoshimura,Mridul Kanti Mandal,Michio Hara,Hideki Fujii,Lee Chuin Chen,Kunio Tanabe,Kenzo Hiraoka,Sen Takeda

Analytical Biochemistry   441 ( 1 )   32 - 37   2013年10月( ISSN：00032697 )

Characterization of ciliary targeting sequence of rat melanin-concentrating hormone receptor 1 査読 重要な業績

Asami Nagata,Akie Hamamoto,Manabu Horikawa,Kentarou Yoshimura,その他2名

General and Comparative Endocrinology   188 ( 188 )   159 - 165   2013年7月( ISSN：00166480 )

質量分析法と統計的学習機械を組み合わせた新規がん診断支援装置の開発 重要な業績

竹田扇,吉村健太郎,出水秀明,平岡賢三,谷畑博司,その他3名

島津評論   3・4 ( 69 )   203 - 210   2013年3月

Biomolecular analysis and cancer diagnostics by negative mode probe electrospray ionization 査読 重要な業績

Mandal MK,Saha S,Yoshimura K,Shida Y,Takeda S,その他2名

Analyst   138 ( 6 )   1682 - 1688   2013年3月( ISSN：00032654 )

Application of Probe Electrospray Ionization Mass Spectrometry (PESI-MS) to Clinical Diagnosis: Solvent Effect on Lipid Analysis 査読 重要な業績

Mandal MK,Yoshimura K,Chen LC,Yu Z,その他5名

Journal of The American Society for Mass Spectrometry   23 ( 11 )   2043 - 2047   2012年11月( ISSN：10440305 )

Solid Probe Assisted Nanoelectrospray Ionization Mass Spectrometry for Biological Tissue Diagnostics 査読 重要な業績

Mridul Kanti Mandal,Kentaro Yoshimura,Subhrakanti Saha,Satoshi Ninomiya,その他7

Analyst   137 ( 20 )   4658 - 4661   2012年10月( ISSN：00032654 )

Analysis of Renal Cell Carcinoma as a First Step for Developing Mass Spectrometry–Based Diagnostics 査読 重要な業績

Kentaro Yoshimura,Lee Chuin Chen,Mridul Kanti Mandal,Tadao Nakazawa,その他9名

Journal of The American Society for Mass Spectrometry   23 ( 10 )   1741 - 1749   2012年10月( ISSN：10440305  eISSN：1879-1123 )

Innovations in Analytical Oncology - Status quo of Mass Spectrometry-Based Diagnostics for Malignant Tumor 査読 重要な業績

Sen Takeda,Kentaro Yoshimura,Kenzo Hiraoka

Journal of Analytical Oncology   1 ( 1 )   74 - 80   2012年6月( ISSN：19277210 )

Hedgehog signaling regulates myelination in the peripheral nervous system through primary cilia 査読 重要な業績

Kentaro Yoshimura,Sen Takeda

Differentiation   83 ( 2 )   S78 - S85   2012年2月( ISSN：03014681 )

Real time analysis of living animals by electrospray ionization mass spectrometry 査読 重要な業績

Kentaro Yoshimura,Lee Chuin Chen,Zhan Yu,Kenzo Hiraoka,Sen Takeda

Analytical Biochemistry   417 ( 2 )   195 - 201   2011年10月( ISSN：00032697 )

Signaling through the Primary Cilium Affects Glial Cell Survival under a Stressed Environment. 査読 重要な業績

Kentaro Yoshimura,Toyoko Kawate,Sen Takeda

Glia   59 ( 2 )   333 - 344   2011年2月( ISSN：08941491 )

Direct analysis of lipids in mouse brain using electrospray droplet impact/SIMS. 査読 重要な業績

Asakawa D,Yoshimura K,Takeda S,Hiraoka K.

Journal of Mass Spectrometry   45 ( 4 )   437 - 443   2010年4月( ISSN：10765174 )

LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation. 査読 重要な業績

Masahiro Shibata,Kentaro Yoshimura,Hirosumi Tamura,Takashi Ueno,その他7名

Biochemical and Biophysical Research Communications   393 ( 2 )   274 - 279   2010年3月( ISSN：0006291X )

Ambient imaging mass spectrometry by electrospray ionization using solid needle as sampling probe 査読 重要な業績

Lee Chuin Chen,Kentaro Yoshimura,Zhan Yu,Rikiya Iwata,Hajime Ito,その他6名

Journal of Mass Spectrometry   44 ( 10 )   1469 - 1477   2009年10月( ISSN：10765174 )

Physical properties of the probe electrospray ionization (PESI) needle applied to the biological samples 査読 重要な業績

Kentaro Yoshimura,Lee Chuin Chen,Daiki Asakawa,Kenzo Hiraoka,Sen Takeda

Journal of Mass Spectrometry   44 ( 6 )   978 - 985   2009年6月( ISSN：10765174 )

The MAP1-LC3 conjugation system is involved in lipid droplet formation 査読 重要な業績

Masahiro Shibata※,Kentaro Yoshimura※,Norihiko Furuya,Masato Koike,Takashi Ueno,その他5名

Biochemical and Biophysical Research Communications   382 ( 2 )   419 - 423   2009年5月( ISSN：0006291X )

Hepatic gap junctions in the hepatocarcinogen-resistant DRH rat. 査読 重要な業績

Gotow T,Shiozaki M,Higashi T,Yoshimura K,Shibata M,他２名

Histochemistry and Cell Biology   130 ( 3 )   583 - 594   2008年9月( ISSN：09486143 )

Morphological and biochemical signs of age-related neurodegenerative changes in klotho mutant mice. 査読 重要な業績

Shiozaki M,Yoshimura K,Shibata M,Koike M,Matsuura N,他2名

Neuroscience   152 ( 4 )   924 - 941   2008年4月( ISSN：03064522 )

Autophagy-physiology and pathophysiology. 重要な業績

Uchiyama Y,Shibata M,Koike M,Yoshimura K,Sasaki M

Histochemistry and Cell Biology   129 ( 4 )   407 - 420   2008年4月( ISSN：09486143  eISSN：1432-119X )

Effects of RNA interference of Atg4B on the limited proteolysis of LC3 in PC12 cells and expression of Atg4B in various rat tissues. 査読 重要な業績

Yoshimura K,Shibata M,Koike M,Gotoh K,Fukaya M,その他2名

Autophagy   2 ( 3 )   200 - 208   2006年7月( ISSN：15548627 )

Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease). 査読 重要な業績

Koike M,Shibata M,Waguri S,Yoshimura K,Tanida I,その他7名

The American Journal of Pathology   167 ( 6 )   1713 - 1728   2005年12月( ISSN：00029440 )