Updated on 2025/02/07

写真a

 
Hideki Yui
 
Organization
Graduate Faculty of Interdisciplinary Research Faculty of Medicine Basic Science for Clinical Medicine (Center for Birth Cohort Studies) Assistant Professor
Title
Assistant Professor

Research History

  • RIKEN   RIKEN Center for Integrative Medical Sciences   Research Scientist

    2024.2

  • University of Yamanashi   Graduate Faculty of Interdisciplinary Research Faculty of Medicine

    2021.1

  • Health Care Science Institute   Researcher

    2020.4 - 2020.12

  • Japan Society for the Promotion of Science   Research Fellowship for Young Scientists (PD)

    2017.4 - 2020.3

  • Ritsumeikan University The Kinugasa Research Organization   Senior Researcher

    2014.4 - 2017.3

  • Japan Society for the Promotion of Science   Research Fellowship for Young Scientists (DC2)

    2012.4 - 2014.3

  • 京都府家庭支援総合センター   児童一時保護部門   宿日直児童指導員

    2010.4 - 2012.3

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Education

  • 立命館大学大学院

    - 2014.3

  • Kyoto Prefectural University

    - 2011.3

  • Kyoto Prefectural University

    - 2009.3

Degree

  • 博士（学術）

Research Areas

  • Humanities & Social Sciences / Philosophy and ethics

  • Humanities & Social Sciences / Sociology of science, history of science and technology

  • Humanities & Social Sciences / Philosophy and ethics  / 生命倫理

  • Life Science / Medical management and medical sociology

  • Humanities & Social Sciences / Gender studies

Research Interests

  • Reproduction, Medicine, History, Family, Gender, Bioethics

Subject of research

  • 生殖と医療をめぐる倫理

  • 再生医療の倫理

Research Projects

  • 色覚検査と就業制限をめぐる論争と制度の変遷過程の分析

    2024.10 - 2025.9

    三菱財団  三菱財団研究助成（人文科学） 

    由井秀樹

  • 中高生になった研究参加者との共創による出生コホート研究とELSIの検討のための企画調査

    2024.10 - 2025.3

    JST-RISTEX  科学技術の倫理的・法制度的・社会的課題（ELSI）への包括的実践研究開発プログラム（RInCA） 

    由井秀樹,武藤香織,李怡然,小田和早苗

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    Authorship：Principal investigator 

  • 「ヘルスケア政策史研究」領域創成の基盤構築とアーカイブズ整備－PPIの実践と共に

    Grant number：23K17288  2023.6 - 2026.3

    日本学術振興会  科学研究費助成事業  挑戦的研究(開拓)

    後藤 基行, 川端 美季, 渡部 沙織, 舟津 悠紀, 松田 亮三, 竹島 正, 美馬 達哉, 佐藤 沙織, 由井 秀樹, 久保田 明子, 赤司 友徳, 松原 洋子

  • アーカイブ構築に基づく優生保護法史研究

    2021.4 - 2024.3

    松原洋子、末田 邦子, 坂井 めぐみ, 松田 亮三, 美馬 達哉, 中村 江里, 松岡 弘之, 橋本 明, 由井 秀樹, 久保田 明子, 後藤 基行

  • 日本における非配偶者間人工授精の実施状況に関する歴史研究

    2020.9 - 2021.3

    日本学術振興会  科学研究補助金（研究活動スタート支援） 

    由井秀樹

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    Authorship：Principal investigator 

  • 母子保健の「標準化像」の形成過程に関する歴史的研究

    2017.5 - 2019.4

    トヨタ財団  トヨタ財団研究助成 

    由井 秀樹

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    Authorship：Principal investigator  Grant type：Competitive 

  • A Historical Study on Male Infertility and Masculinity in Post-War Japan

    Grant number：15K21496  2015.4 - 2017.3

    Japan Society for the Promotion of Science  Ritsumeikan University  Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)  Grant-in-Aid for Young Scientists (B)

    Yui Hideki

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    Authorship：Principal investigator 

    This study analyzes the interpretation of male infertility in post-war Japan. To clarify the points, the human relations column of the Yomiuri newspaper from the 1950s to the 2010s and policy documents referring to male infertility were examined. The results suggest the following point. Control of women’s bodies by the country is strengthened through men’s awareness of their reproductive responsibilities, which occurs through Japan’s teachings that identify male infertility as a countermeasure to declining birthrates. This point seems to link to progress in gender studies.

  • 体外受精研究のフレームに関する歴史研究ーー１９６０～８０年代の日本の展開

    2015.2 - 2016.1

    上廣倫理財団研究助成 

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    Grant type：Competitive 

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Papers

  • Low glucose challenge test result as a potential risk factor for delays in early child development: the Japan environment and children’s study

    Satoshi Shinohara, Reiji Kojima, Sanae Otawa, Megumi Kushima, Kunio Miyake, Hideki Yui, Tadao Ooka, Sayaka Horiuchi, Hiroshi Yokomichi, Zentaro Yamagata, Ryoji Shinohara

    Journal of Diabetes & Metabolic Disorders   24 ( 1 )   2025.2(  eISSN：2251-6581 )

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

    DOI： 10.1007/s40200-025-01568-x

    Other Link： https://link.springer.com/article/10.1007/s40200-025-01568-x/fulltext.html

  • The association of environmental house dust mite allergens and crustacean allergy: the Japan Environment and Children’s Study (JECS)

    Reiji Kojima, Ryoji Shinohara, Megumi Kushima, Hideki Yui, Sanae Otawa, Sayaka Horiuchi, Kunio Miyake, Hiroshi Yokomichi, Yuka Akiyama, Tadao Ooka, Zentaro Yamagata

    Asia Pacific Allergy   2025.1( ISSN：2233-8276  eISSN：2233-8268 )

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Ovid Technologies (Wolters Kluwer Health)  

    Background:

    The higher crustacean allergy prevalence in Asia than in Western regions may be due to a shrimp–mite cross-reaction. A high environmental house dust mite prevalence may lead to increased house dust mite sensitization and thereby increase the prevalence of crustacean allergy.

    Objective:

    To determine the association between environmental house dust mite allergens and crustacean allergy in Japanese preschool children.

    Methods:

    We used data from 4,242 mother–infant dyads who participated in the subcohort study of the Japan Environment and Children’s Study, a prospective birth cohort study. A logistic regression model was used to analyze the association between house dust mite allergens in dust at 18 months and 3 years of age and crustacean allergy at the age of 4 years.

    Results:

    The crustacean allergy prevalence was 0.4%. Greater house dust mite exposure at 18 months of age was associated with a higher prevalence of crustacean allergy, although this association was not statistically significant. However, there was no positive association between house dust mite exposure at 3 years of age and crustacean allergy.

    Conclusions:

    No association between house dust mite allergen exposure in infancy and the risk of crustacean allergy at preschool age was apparent. Follow-up studies, including investigation of tropomyosin sensitization in schoolchildren, are required.

    DOI： 10.5415/apallergy.0000000000000169

  • 研究倫理の制度ーー現状と課題及びその歴史 Invited

    由井秀樹

    科学史研究   ( 312 )   381 - 383   2025.1

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    Language：Japanese   Publishing type：(MISC) Prompt report, short report, and research note, etc. (scientific journal)  

  • Maternal alcohol consumption during pregnancy and child development: Role of ADH1B and ALDH2 gene polymorphisms-The Yamanashi Adjunct Study of the Japan Environment and Children's Study.

    Kunio Miyake, Sanae Otawa, Megumi Kushima, Hideki Yui, Ryoji Shinohara, Sayaka Horiuchi, Yuka Akiyama, Tadao Ooka, Reiji Kojima, Hiroshi Yokomichi, Zentaro Yamagata

    Alcohol, clinical & experimental research   2024.11

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    Language：English   Publishing type：Research paper (scientific journal)  

    BACKGROUND: The role of polymorphisms in genes regulating alcohol metabolism, particularly those modulating the impact of prenatal alcohol exposure on the neurodevelopment of offspring, remains inconclusive. Herein, we aimed to determine the involvement of ADH1B and ALDH2 gene polymorphisms in maternal alcohol consumption during pregnancy and the risk of developmental delay in offspring in a Japanese population. METHODS: We analyzed 1727 mother-child pairs from the Yamanashi Adjunct Study of the Japan Environment and Children's Study. Maternal alcohol consumption during pregnancy was determined through a mid-pregnancy questionnaire and categorized into three groups: never-drinkers, those who quit drinking in early pregnancy, and current drinkers. Developmental delays in children were assessed in five domains using the Japanese version of the Ages and Stages Questionnaire, Third Edition (J-ASQ-3) at 3 years of age. We conducted a logistic regression analysis to explore the relationship between maternal drinking status during pregnancy and developmental delays in offspring with respect to maternal ADH1B (rs1229984) or ALDH2 (rs671) gene polymorphisms. RESULTS: Children born to mothers who continued alcohol consumption during pregnancy had a higher risk of delayed communication skills at 3 years of age compared with children born to mothers who did not drink alcohol (adjusted odds ratio [OR], 5.82; 95% confidence interval, 1.84-18.38). Analysis by ALDH2 gene polymorphism revealed that alcohol consumption by mothers carrying the wild-type ALDH2 (*1/*1) increased the risk of delayed communication skills at 3 years of age, whereas alcohol consumption by mothers carrying a heterozygotic genotype of ALDH2 (*1/*2) enhanced the risk of developmental delay in all five domains of the J-ASQ-3. The impact of ADH1B gene polymorphism could not be clearly elucidated. CONCLUSIONS: Our results suggest that alcohol consumption by pregnant females carrying the deficient variant ALDH2*2 genotype may increase the risk of developmental delay in their offspring.

    DOI： 10.1111/acer.15487

    PubMed

  • Association of Japanese cedar pollen sensitization in children with Dermatophagoides pteronyssinus sensitization and maternal sensitization: Insights from the Yamanashi adjunct study within the Japan Environment and Children’s Study (JECS)

    Ayumi Shimamura, Ryoji Shinohara, Megumi Kushima, Sanae Otawa, Hideki Yui, Tomokazu Matsuoka, Daisuke Watanabe, Hiroshi Yokomichi, Kunio Miyake, Reiji Kojima, Zentaro Yamagata, Daiju Sakurai

    Allergology International   2024.11( ISSN：1323-8930 )

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

    DOI： 10.1016/j.alit.2024.11.002

  • 優生保護法第4条に基づく強制不妊手術対象者の探索――1950年代北海道の保健所の事業からの検討 Reviewed

    由井秀樹

    生命倫理   34 ( 1 )   86 - 95   2024.9

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    Language：Japanese   Publishing type：Research paper (scientific journal)  

  • Neonatal transfer and duration of hospitalization of newborns as potential risk factors for impaired mother-infant bonding: The Japan Environment and Children's Study Reviewed

    Satoshi Shinohara, Ryoji Shinohara, Reiji Kojima, Sanae Otawa, Megumi Kushima, Kunio Miyake, Hideki Yui, Tadao Ooka, Yuka Akiyama, Sayaka Horiuchi, Hiroshi Yokomichi, Zentaro Yamagata

    Journal of Affective Disorders   360   314 - 321   2024.9( ISSN：0165-0327 )

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

    DOI： 10.1016/j.jad.2024.06.001

  • Maternal excessive weight gain as a potential risk factor for prolonged labor in Japanese pregnant women: The Japan Environment and Children’s Study

    Satoshi Shinohara, Sayaka Horiuchi, Reiji Kojima, Ryoji Shinohara, Sanae Otawa, Megumi Kushima, Kunio Miyake, Hideki Yui, Tadao Ooka, Yuka Akiyama, Hiroshi Yokomichi, Zentaro Yamagata

    PLOS ONE   19 ( 7 )   e0306247 - e0306247   2024.7(  eISSN：1932-6203 )

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Public Library of Science (PLoS)  

    Aim

    This study aimed to determine whether excessive maternal weight gain during pregnancy was associated with a higher risk of prolonged labor.

    Methods

    We analyzed the data regarding maternal weight gain during pregnancy for the participants of Japan Environment and Children’s Study (JECS), which is an ongoing nationwide prospective birth cohort study in Japan. After excluding participants with multiple pregnancies, with deliveries before 37 or beyond 42 weeks of gestation, or who had undergone cesarean section, 71,154 (nulliparous, n = 28,442) Japanese women were included. Prolonged labor was defined by a cutoff ranking at the 95th percentile and consequently defined as labor duration exceeding 12.7 h in multiparous women and exceeding 23.2 h in nulliparous women. These classifications were made according to labor curves established by the Japanese Society of Obstetrics and Gynecology Perinatal Committee developed in June 2021. Considering that no studies have conducted an investigation based on this new guideline, we analyzed the association between excessive maternal weight gain during pregnancy and prolonged labor by parity.

    Results

    The overall incidence of prolonged labor was 10.2% (2,907/28,442) in nulliparous women and 6.1% (2,597/42,712) in multiparous women. Multivariable analysis indicated that excessive maternal weight gain was significantly associated with prolonged labor in nulliparous (adjusted odds ratio, 1.21; 95% confidence interval, 1.10–1.32) and multiparous women (adjusted odds ratio, 1.15; 95% confidence interval, 1.05–1.27). Kaplan–Meier survival analysis showed that as labor progressed, the percentage of women who had not yet delivered was higher among those with excessive maternal weight gain than among those with normal maternal weight gain in both the nulliparous (median labor duration 12.9 h vs 12.2 h, p<0.001) and multiparous (median labor duration 6.2 h vs 5.8 h, p<0.001) groups.

    Conclusion

    Excessive maternal weight gain was significantly associated with prolonged labor in Japanese women.

    DOI： 10.1371/journal.pone.0306247

  • Opinions on research involving human embryo models by researchers and the general public Reviewed

    Hideki Yui, Yoshimi Yashiro, Kaori Muto, Saori Watanabe, Yukitaka Kiya, Yusuke Inoue, Zentaro Yamagata

    Regenerative Therapy   26   9 - 13   2024.6( ISSN：2352-3204 )

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

    DOI： 10.1016/j.reth.2024.05.001

  • Attitudes of patients with IVF/ICSI toward human embryo in vitro culture beyond 14 days

    Yukitaka Kiya, Saori Watanabe, Kana Harada, Hideki Yui, Yoshimi Yashiro, Kaori Muto

    Regenerative Therapy   26   831 - 836   2024.6( ISSN：2352-3204 )

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

    DOI： 10.1016/j.reth.2024.09.005

  • 書評『ツベルクリン騒動ーー明治日本の医と情報』（月澤美代子著、名古屋大学出版会、2022年）

    由井秀樹

    科学史研究   ( 309 )   114 - 117   2024.4

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    Language：Japanese   Publishing type：(MISC) Book review and document introduction, etc.  

  • Association of maternal leukocyte, monocyte, and neutrophil counts with hypertensive disorders of pregnancy: the Japan Environment and Children’s Study (JECS) Reviewed

    Shiori Ishiyama, Kazuki Mochizuki, Ryoji Shinohara, Kunio Miyake, Megumi Kushima, Reiji Kojima, Sayaka Horiuchi, Sanae Otawa, Hideki Yui, Tadao Ooka, Yuka Akiyama, Hiroshi Yokomichi, Zentaro Yamagata, Michihiro Kamijima, Shin Yamazaki, Yukihiro Ohya, Reiko Kishi, Nobuo Yaegashi, Koichi Hashimoto, Chisato Mori, Shuichi Ito, Zentaro Yamagata, Hidekuni Inadera, Takeo Nakayama, Tomotaka Sobue, Masayuki Shima, Seiji Kageyama, Narufumi Suganuma, Shoichi Ohga, Takahiko Katoh

    Scientific Reports   14 ( 1 )   2024.3(  eISSN：2045-2322 )

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

    Abstract

    Hypertensive disorders of pregnancy (HDP) increase the risk of preterm births and cesarean delivery. This study aimed to investigate whether maternal blood leukocyte, monocyte, or neutrophil counts in the first trimester are related to the development of HDP. Data were collected from the Japan Environment and Children’s Study, a large birth cohort study (n = 38,194) that recruited pregnant women in 15 Regional Centers across Japan (from January 2011 to March 2014). The odds ratios (ORs) for mild/severe HDP according to the cut-off value of leukocyte/neutrophil/monocyte counts by the receiver operating characteristic curve showed high ORs. Furthermore, pregnant women with the highest quartiles of leukocyte and monocyte counts had higher adjusted ORs (aORs) for mild (leukocyte: aOR = 1.27, 95% confidence interval [CI]: 1.02–1.58; monocyte: aOR = 1.30, 95% CI 1.04–1.63) and severe HDP (leukocyte: aOR = 1.51, 95% CI 1.08–2.13; monocyte: aOR = 1.44, 95% CI 1.03–2.01) compared with those with the lowest quartiles of those counts. In addition, pregnant women with the highest neutrophil counts had higher aOR for mild HDP (aOR = 1.26, 95% CI 1.02–1.56) compared with those with the lowest count. In conclusion, high leukocyte and monocyte counts in the first trimester are associated with the development of HDP. Thus, they may be used to predict subsequent HDP.

    DOI： 10.1038/s41598-024-55623-3

    Other Link： https://www.nature.com/articles/s41598-024-55623-3

  • 1950年代から60年代日本における家族計画と優生手術ーー優生保護法第3条に基づく優生手術 Reviewed

    由井秀樹

    立命館人間科学研究   ( 48 )   33 - 46   2024.3

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    Language：Japanese   Publishing type：Research paper (scientific journal)  

  • Association between filaggrin gene mutations and the clinical features of molluscum contagiosum: The Yamanashi Adjunct Study of the Japan Environment and Children's Study Reviewed

    Reiji Kojima, Kunio Miyake, Ryoji Shinohara, Megumi Kushima, Hideki Yui, Sanae Otawa, Sayaka Horiuchi, Hiroshi Yokomichi, Yuka Akiyama, Tadao Ooka, Zentaro Yamagata

    The Journal of Dermatology   2024.2( ISSN：0385-2407  eISSN：1346-8138 )

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Wiley  

    Abstract

    Previous studies have reported swimming, atopic dermatitis, and filaggrin (FLG) gene mutations as risk factors for molluscum contagiosum (MC) infection. FLG gene mutations impair skin barrier function. The aim of this study was to determine the impact of FLG mutations on the incidence and clinical features of MC. We used data from 2036 children who participated in the Yamanashi Adjunct Study of the Japan Environment and Children's Study, a prospective, birth cohort study. A questionnaire for caregivers (when children were 4 and 8 years of age) asked about clinical features including previous MC incidence and treatment, number of MC lesions at first visit, and time to resolution. Participants underwent genotyping to detect six FLG mutations that are common in the Japanese population. A logistic regression model was used to analyze the association between MC incidence and FLG mutations, adjusted for potential confounders. The cumulative incidence of MC at age 8 years was 47.1%. Among participants with a history of MC, 67.6% had undergone curettage. FLG mutation was a significant risk factor for MC incidence (adjusted odds ratio [aOR] 1.69, 95% confidence interval [CI] 1.18–2.42). Swimming and atopic dermatitis were also significant risk factors for MC. There was no significant association between FLG mutation and the number of MC lesions at the first visit or the time to resolution of lesions. FLG mutation is a risk factor for MC incidence; however, FLG mutations do not affect the number of MC lesions at presentation or the time to resolution.

    DOI： 10.1111/1346-8138.17157

  • 採血を伴う医学研究に対する小児自身による評価――動的プロセスとしてのインフォームド・アセント Invited

    由井秀樹

    メディカルエシックス   ( 67 )   78 - 86   2024.2

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    Language：Japanese   Publishing type：Research paper (scientific journal)  

  • 小児の昼間尿失禁と夜尿症に関与する因子:横断的コホート研究(エコチル調査より)

    志村寛史, 土屋幸子, 神田美恵, 垣渕由岐子, 澤田智史, 小田和早苗, 久島萌, 秋山有佳, 大岡忠生, 小島令嗣, 由井秀樹, 三宅邦夫, 横道洋司, 篠原亮次, 山縣然太朗, 三井貴彦

    日本小児泌尿器科学会雑誌   33 ( 2 )   2024( ISSN：1341-0784 )

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    Language：Japanese   Publishing type：(MISC) Summary of the papers read (national conference and other science council)  

    J-GLOBAL

  • Obesity as a potential risk factor for stillbirth: The Japan Environment and Children's Study. Reviewed

    Satoshi Shinohara, Ryoji Shinohara, Reiji Kojima, Sayaka Horiuchi, Sanae Otawa, Megumi Kushima, Kunio Miyake, Hideki Yui, Tadao Ooka, Yuka Akiyama, Hiroshi Yokomichi, Zentaro Yamagata

    Preventive medicine reports   35   102391 - 102391   2023.10

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    Language：English   Publishing type：Research paper (scientific journal)  

    The relationship between high body mass index (BMI) >25 kg/m2 and risk for stillbirth in the Japanese population remains unclear. This study aimed to estimate the impact of maternal obesity on the risk of stillbirth in a Japanese population. This prospective cohort study used data from the Japan Environment and Children's Study, which recruited pregnant individuals between 2011 and 2014. A total of 93,772 fetuses were considered eligible for inclusion in this study. Stillbirth (fetal death before or during labor at ≥22 completed weeks of gestation) rates were compared among four pre-pregnancy BMI groups: underweight (<18.5 kg/m2), reference (18.5 to <25.0 kg/m2), overweight (25.0 to <30.0 kg/m2), and obese (≥30.0 kg/m2). The association between pre-pregnancy BMI and the risk of stillbirth was estimated using multiple logistic regression analyses. The overall stillbirth incidence was 0.33% (305/93,722). Compared with the reference group, the risk of stillbirth was significantly higher in the overweight group (adjusted odds ratio [aOR]: 1.55; 95% confidence interval [CI]: 1.08-2.23) and the obese group (aOR: 2.60; 95% CI: 1.59-4.24). The overall incidence of early stillbirth (i.e., <28 weeks) was 0.17% (155/93,722). Similarly, after adjusting for potential confounding factors, the risk of early stillbirth was significantly higher in the obese group (aOR: 4.33; 95% CI: 2.44-7.70). Increased maternal BMI was associated with an increased risk of stillbirth in the Japanese population. Therefore, counselling women planning for pregnancy on the importance of an appropriate pre-pregnancy BMI to minimize the risk of stillbirth is important.

    DOI： 10.1016/j.pmedr.2023.102391

    PubMed

  • 小児採血では、わかりやすく簡潔な理由の説明が重要 Invited

    由井秀樹, 小田和早苗, 久島萌, 篠原亮二, 山縣然太朗

    Medical Technology   51 ( 11 )   1100 - 1101   2023.10

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    Language：Japanese   Publishing type：(MISC) Introduction and explanation (commerce magazine)  

  • 人口の増減と家族を形成する計画ーー知識啓発のその先に Invited

    由井秀樹

    大阪保険医雑誌   ( 686 )   17 - 20   2023.10

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    Language：Japanese   Publishing type：(MISC) Introduction and explanation (others)  

  • わが国の生殖医療の歴史 Invited

    由井秀樹

    腎臓内科   18 ( 3 )   391 - 395   2023.9

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    Language：Japanese   Publishing type：(MISC) Introduction and explanation (commerce magazine)  

  • Maternal dietary fiber intake during pregnancy and child development: the Japan Environment and Children's Study Reviewed

    Kunio Miyake, Sayaka Horiuchi, Ryoji Shinohara, Megumi Kushima, Sanae Otawa, Hideki Yui, Yuka Akiyama, Tadao Ooka, Reiji Kojima, Hiroshi Yokomichi, Kazuki Mochizuki, Zentaro Yamagata

    Frontiers in Nutrition   10   2023.7(  eISSN：2296-861X )

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Frontiers Media SA  

    Background

    Animal studies have shown that maternal low-fiber diets during pregnancy may impair brain development and function in offspring, but this has not been validated by epidemiological studies. The aim of this study was to investigate the link between maternal dietary fiber intake during pregnancy and neurodevelopmental delay in offspring using a large birth cohort.

    Methods

    A total of 76,207 mother-infant pairs were analyzed using data from the Japan Environment and Children's Study, a nationwide prospective cohort study. Maternal dietary fiber intake was estimated using the food frequency questionnaire in mid-pregnancy. Maternal dietary fiber intake was adjusted for energy and classified into quintiles. Developmental delay was assessed in five domains using the Japanese version of the Ages and Stages Questionnaire, Third Edition at the age of 3 years. The logistic regression analysis was performed to estimate the odds ratio (OR) and 95% confidence interval (CI) for the link between dietary fiber intake during pregnancy and developmental delay at the age of 3 years.

    Results

    The lowest intake group of total dietary fiber had a higher risk of delayed communication [adjusted OR (aOR), 1.51; 95% CI, 1.32–1.74], fine motor (aOR, 1.45; 95% CI, 1.32–1.61), problem-solving (aOR, 1.46; 95% CI, 1.32–1.61), and personal-social skills (aOR, 1.30; 95% CI, 1.12–1.50) than did the highest intake group. An analysis that excluded the effects of insufficient folic acid intake during pregnancy also showed a similar trend.

    Conclusion

    This study showed that maternal dietary fiber deficiency during pregnancy might influence an increased risk of neurodevelopmental delay in offspring.

    DOI： 10.3389/fnut.2023.1203669

  • A nationwide, prospective, cohort study on exogenous oxytocin and delays in early child development: the Japan environment and children’s study

    Satoshi Shinohara, Sayaka Horiuchi, Ryoji Shinohara, Sanae Otawa, Megumi Kushima, Kunio Miyake, Hideki Yui, Reiji Kojima, Tadao Ooka, Yuka Akiyama, Hiroshi Yokomichi, Zentaro Yamagata, Annick Buchholz, Zentaro Yamagata, Michihiro Kamijima, Shin Yamazaki, Yukihiro Ohya, Reiko Kishi, Nobuo Yaegashi, Koichi Hashimoto, Chisato Mori, Shuichi Ito, Hidekuni Inadera, Takeo Nakayama, Tomotaka Sobue, Masayuki Shima, Hiroshige Nakamura, Narufumi Suganuma, Koichi Kusuhara, Takahiko Katoh

    European Journal of Pediatrics   182 ( 9 )   4059 - 4068   2023.7(  eISSN：1432-1076 )

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

    DOI： 10.1007/s00431-023-05079-w

    Other Link： https://link.springer.com/article/10.1007/s00431-023-05079-w/fulltext.html

  • Attitudes towards human fetal tissue research: Survey of researchers and the public in Japan Reviewed

    Hideki Yui, Ayako Kamisato, Kaori Muto, Yoshimi Yashiro, Saori Watanabe, Yukitaka Kiya, Kumiko Fujisawa, Yusuke Inoue, Zentaro Yamagata

    Regenerative Therapy   ( 24 )   78 - 84   2023.6

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1016/j.reth.2023.05.007

  • Interpregnancy weight change as a potential risk factor for large-for-gestational-age infants: the Japan Environment and Children’s Study Reviewed

    Satoshi Shinohara, Sayaka Horiuchi, Ryoji Shinohara, Sanae Otawa, Megumi Kushima, Kunio Miyake, Hideki Yui, Reiji Kojima, Tadao Ooka, Yuka Akiyama, Hiroshi Yokomichi, Zentaro Yamagata

    The Journal of Maternal-Fetal &amp; Neonatal Medicine   36 ( 1 )   2023.5( ISSN：1476-7058  eISSN：1476-4954 )

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Informa UK Limited  

    DOI： 10.1080/14767058.2023.2209251

  • Survey of Japanese researchers and the public regarding the culture of human embryos in vitro beyond 14 days Reviewed

    Hideki Yui, Kaori Muto, Yoshimi Yashiro, Saori Watanabe, Yukitaka Kiya, Kumiko Fujisawa, Kana Harada, Yusuke Inoue, Zentaro Yamagata

    Stem Cell Reports   2023.3( ISSN：2213-6711 )

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    Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1016/j.stemcr.2023.02.005

  • Multiple pregnancy as a potential risk factor for postpartum depression: The Japan Environment and Children's Study Reviewed

    Satoshi Shinohara, Sayaka Horiuchi, Ryoji Shinohara, Sanae Otawa, Megumi Kushima, Kunio Miyake, Hideki Yui, Reiji Kojima, Tadao Ooka, Yuka Akiyama, Hiroshi Yokomichi, Zentaro Yamagata

    JOURNAL OF AFFECTIVE DISORDERS   ( 329 )   218 - 224   2023.3( ISSN：0165-0327 )

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    Language：English   Publishing type：Research paper (scientific journal)  

  • 精子提供をめぐる論点ーー日本における非配偶者間人工授精の過去の実施状況、議論から

    由井秀樹

    医学哲学・医学倫理   ( 40 )   56 - 60   2023.1

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    Authorship：Lead author,　Last author,　Corresponding author   Language：Japanese   Publishing type：(MISC) Prompt report, short report, and research note, etc. (scientific journal)   Publisher：日本医学哲学・倫理学会  

  • Retrospective analysis on gestational weight gain in twin pregnancies with favorable perinatal outcomes: The Japan Environment and Children's Study (JECS)

    Satoko TAKAOKA, Yasue KOBAYASHI, Ryoji SHINOHARA, Sayaka HORIUCHI, Megumi KUSHIMA, Sanae OTAWA, Hiroshi YOKOMICHI, Kunio MIYAKE, Reiji KOJIMA, Yuka AKIYAMA, Tadao OOKA, Hideki YUI, Zentaro YAMAGATA

    Journal of Japan Academy of Midwifery   2023( ISSN：0917-6357  eISSN：1882-4307 )

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Japan Academy of Midwifery  

    DOI： 10.3418/jjam.jjam-2022-0043

  • 小児の尿禁制獲得時期に関与する因子~縦断的コホート研究(エコチル調査より)~

    志村寛史, 土屋幸子, 神田美恵, 土田哲司, 垣渕由岐子, 澤田智史, 小田和早苗, 堀内清華, 久島萌, 三宅邦夫, 秋山有佳, 大岡忠生, 小島令嗣, 由井秀樹, 横道洋司, 篠原亮次, 山縣然太朗, 三井貴彦

    日本排尿機能学会誌(Web)   34 ( 1 )   2023( ISSN：1347-6513 )

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    Language：Japanese   Publishing type：(MISC) Summary of the papers read (national conference and other science council)  

    J-GLOBAL

  • Infantile peanut introduction and peanut allergy in regions with a low prevalence of peanut allergy: the Japan Environment and Children’s Study (JECS) Reviewed

    Reiji Kojima, Ryoji Shinohara, Megumi Kushima, Hideki Yui, Sanae Otawa, Sayaka Horiuchi, Kunio Miyake, Hiroshi Yokomichi, Yuka Akiyama, Tadao Ooka, Zentaro Yamagata

    Journal of Epidemiology   2023( ISSN：0917-5040  eISSN：1349-9092 )

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Japan Epidemiological Association  

    DOI： 10.2188/jea.je20230210

  • Appropriate procedures to increase the adherence of children to blood collection: A cross‐sectional study Reviewed

    Hideki Yui, Sanae Otawa, Sayaka Horiuchi, Megumi Kushima, Ryoji Shinohara, Reiji Kojima, Yuka Akiyama, Tadao Ooka, Kunio Miyake, Hiroshi Yokomichi, Zentaro Yamagata

    Health Science Reports   6 ( 1 )   2022.12

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：Wiley  

    DOI： 10.1002/hsr2.1036

  • 書評『近代日本の優生学ーー〈他者〉像の成立をめぐって』（本多創史著、明石出版、2022年）

    科学史研究   ( 302 )   193 - 195   2022.7

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    Authorship：Lead author,　Last author,　Corresponding author   Language：Japanese   Publishing type：(MISC) Book review and document introduction, etc.   Publisher：日本科学史学会  

  • ヒト胚の体外培養可能期間をめぐる科学者コミュニティの動向

    由井秀樹

    科学史研究   ( 302 )   181 - 184   2022.7

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    Authorship：Lead author,　Last author,　Corresponding author   Language：Japanese   Publishing type：(MISC) Introduction and explanation (scientific journal)   Publisher：日本科学史学会  

  • 書評「近代日本の優生学ーー〈他者〉像の成立をめぐって」（本多創史著、明石出版、2022年）

    由井秀樹

    科学史研究   ( 302 )   2022.7

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    Language：Japanese   Publishing type：(MISC) Introduction and explanation (scientific journal)  

  • Comparison of the 2021 International Society for Stem Cell Research (ISSCR) guidelines for “laboratory-based human stem cell research, embryo research, and related research activities” and the corresponding Japanese regulations Reviewed

    Hideki Yui, Kaori Muto, Yoshimi Yashiro, Saori Watanabe, Yukitaka Kiya, Ayako Kamisato, Yusuke Inoue, Zentaro Yamagata

    Regenerative Therapy   2022.5( ISSN：2352-3204 )

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：ELSEVIER  

    DOI： htt10.1016/j.reth.2022.05.002

  • ヒト胎児組織の研究利用と倫理指針ーーヒト幹細胞を用いた臨床研究の在り方に関する専門委員会における議論の分析から Reviewed

    由井秀樹, 山縣然太朗

    医療と社会   32 ( 1 )   95 - 107   2022.4

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    Authorship：Lead author   Language：Japanese   Publishing type：(MISC) Prompt report, short report, and research note, etc. (bulletin of university, research institution)   Publisher：公益財団法人医療科学研究所  

    DOI： 10.4091/iken.2022.001

  • 書評 『日本の男性不妊ーー当事者の語りから』（竹家一美著、晃洋書房、2021年）

    由井秀樹

    家族社会学研究   34 ( 1 )   2022.4

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    Authorship：Lead author   Language：Japanese   Publishing type：(MISC) Book review and document introduction, etc.  

  • 国際幹細胞学会（ISSCR）2021 年版ガイドラインにおける実験室で⾏う ヒト幹細胞、胚関連研究の取扱い ― ⽇本の関連指針との⽐較検討 Reviewed

    由井秀樹, 武藤⾹織, ⼋代嘉美, 渡部沙織, ⽊⽮幸孝, 神⾥彩⼦, 井上悠輔, ⼭縣然太朗

    CBEL Report   2022.1

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    Authorship：Lead author   Language：Japanese   Publishing type：(MISC) Introduction and explanation (bulletin of university, research institution)   Publisher：東京大学生命倫理連携研究機構  

    Other Link： http://cbel.jp/%e5%9b%bd%e9%9a%9b%e5%b9%b9%e7%b4%b0%e8%83%9e%e5%ad%a6%e4%bc%9a%ef%bc%88isscr%ef%bc%892021-%e5%b9%b4%e7%89%88%e3%82%ac%e3%82%a4%e3%83%89%e3%83%a9%e3%82%a4%e3%83%b3%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b/

  • Factors of parental COVID-19 vaccine hesitancy: A cross sectional study in Japan Reviewed

    Sayaka Horiuchi, Haruka Sakamoto, Sarah K. Abe, Ryoji Shinohara, Megumi Kushima, Sanae Otawa, Hideki Yui, Yuka Akiyama, Tadao Ooka, Reiji Kojima, Hiroshi Yokomichi, Kunio Miyake, Takashi Mizutani, Zentaro Yamagata

    PLoS One   16 ( 12 )   2021.12( ISSN：1932-6203 )

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1371/journal.pone.0261121

  • A History of Japanese Follow-up Surveys of Children Conceived through Artificial Insemination by Donor: The Evidence of “Superior” Children and Positive Eugenics Reviewed

    East Asian Science Technology and Society-An International Journal   2021.10( ISSN：1875-2160 )

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    Authorship：Lead author,　Last author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1080/18752160.2021.1950373

  • 感染症研究と中絶論争 ― 近年のアメリカにおけるヒト胎児組織を⽤いる研究をめぐる動向 Reviewed

    CBEL Report   2021.8

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    Authorship：Lead author   Language：Japanese   Publishing type：Research paper (bulletin of university, research institution)  

    Other Link： http://cbel.jp/%e6%84%9f%e6%9f%93%e7%97%87%e7%a0%94%e7%a9%b6%e3%81%a8%e4%b8%ad%e7%b5%b6%e8%ab%96%e4%ba%89-%e2%80%95-%e8%bf%91%e5%b9%b4%e3%81%ae%e3%82%a2%e3%83%a1%e3%83%aa%e3%82%ab%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b/

  • 新型コロナウイルス流行下における子どものQOLと影響因子:エコチルやまなし追加調査

    堀内清華, 篠原亮次, 久島萌, 小田和早苗, 由井秀樹, 大岡忠生, 小島令嗣, 秋山有佳, 横道洋司, 山縣然太朗

    日本公衆衛生学会総会抄録集(CD-ROM)   80th   2021

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    Language：Japanese   Publishing type：(MISC) Summary of the papers read (national conference and other science council)  

    J-GLOBAL

  • 1920-30年代東京市における低所得層の出産と医療施設 Reviewed

    由井秀樹

    保健医療社会学論集   2020.8

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    Authorship：Lead author,　Last author,　Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

  • 1920-30年代の東京市における低所得層の出産と医療施設 Reviewed

    由井秀樹

    保健医療社会学論集   31 ( 1 )   40 - 50   2020.8

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    Authorship：Lead author   Language：Japanese   Publishing type：Research paper (scientific journal)  

  • Teaching the ‘appropriate’ age for reproduction: from family planning to ‘life plan’ Reviewed

    Hideki Yui

    Japan Forum   2020.7

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    Authorship：Lead author,　Last author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1080/09555803.2020.1749713

  • Child delivery in medical institutions and lifesaving intervention for premature infants before and during World War Ⅱ in Japan

    Hideki Yui

    Studium Historiae Medicae   2020.2

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    Authorship：Lead author,　Last author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

  • 患者の生命短縮をめぐる議論において、カント主義的は貫徹可能か――有馬斉『死ぬ権利はあるか――安楽死、尊厳死、自殺幇助の是非と命の価値』（春風社、2019年）へのコメント Invited

    由井秀樹

    立命館生存学研究   ( 4 )   5 - 9   2020

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    Authorship：Lead author   Language：Japanese   Publishing type：(MISC) Book review and document introduction, etc.  

  • 現代社会における妊娠・出産の意味

    由井 秀樹

    世界の児童と母性   ( 85 )   9 - 12   2019.4

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    Language：Japanese   Publishing type：(MISC) Introduction and explanation (commerce magazine)  

  • 里親・養子縁組・ファミリーホーム

    由井秀樹, 岩朝しのぶ

    小児内科   51 ( 3 )   376 - 379   2019.4

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    Language：Japanese   Publishing type：(MISC) Introduction and explanation (commerce magazine)  

  • 京都市における戦前・戦中期の医療施設出産の動向 Reviewed

    由井秀樹

    医学史研究   2019.3

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    Authorship：Lead author,　Last author,　Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

  • 母子保健政策における不妊対策と家族形成をめぐる現代史

    由井秀樹

    福祉社会研究   2019.3

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    Authorship：Lead author,　Last author,　Corresponding author   Language：Japanese   Publishing type：Research paper (bulletin of university, research institution)  

  • ［科学史入門］体外受精−胚移植の導入と日本の不妊医療研究

    由井 秀樹

    科学史研究   ( 287 )   222 - 225   2018.10

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    Language：Japanese   Publishing type：(MISC) Introduction and explanation (scientific journal)  

  • 書評『〈ハイブリッドな親子〉の社会学——血縁・家族へのこだわりを解きほぐす』 （野辺陽子・松木洋人・日比野由利・和泉広恵・土屋敦 著，青弓社，2016年）

    由井秀樹

    保健医療社会学論集   29 ( 1 )   85   2018

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    Authorship：Lead author   Language：Japanese   Publishing type：(MISC) Book review and document introduction, etc.  

  • 戦後日本の不妊男性に対するまなざし――不妊男性の妻は自身の経験をどのように意味づけてきたか？

    由井秀樹

    インクルーシブ社会研究   2017.3

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    Authorship：Lead author,　Last author,　Corresponding author   Language：Japanese   Publishing type：Research paper (bulletin of university, research institution)  

    Other Link： https://ritsumei.repo.nii.ac.jp/?action=pages_view_main&active_action=repository_view_main_item_detail&item_id=4176&item_no=1&page_id=13&block_id=21

  • 妊娠・出産に関する知識と少子化対策における人口の質

    由井秀樹

    インクルーシブ社会研究   2017.3

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    Authorship：Lead author,　Last author,　Corresponding author   Language：Japanese   Publishing type：Research paper (bulletin of university, research institution)  

    Other Link： http://hdl.handle.net/10367/8096

  • 書評『これからの子ども社会学――生物・技術・社会のネットワークとしての「子ども」』（アラン・プラウト著、元森絵里子訳，新曜社，2016年） Invited

    由井秀樹

    家族社会学研究   29 ( 2 )   235   2017

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    Language：Japanese   Publishing type：(MISC) Book review and document introduction, etc.  

  • 書評『新版 現代医療の社会学――日本の現状と課題』（中川輝彦・黒田浩一郎編，世界思想社，2015年） Invited

    由井秀樹

    科学史研究   ( 282 )   165 - 168   2017( ISSN：2188-7535 )

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    Language：Japanese   Publishing type：(MISC) Book review and document introduction, etc.   Publisher：日本科学史学会 ; 2014-  

    CiNii Books

  • 体外受精の臨床応用と日本受精着床学会の設立 Reviewed

    由井秀樹

    科学史研究   2016.7

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    Authorship：Lead author,　Last author,　Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

  • 体外受精の臨床応用と日本産科婦人科学会の「見解」

    由井秀樹

    生存学研究センター報告   2016.3

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    Authorship：Lead author,　Last author,　Corresponding author   Language：Japanese   Publishing type：Research paper (bulletin of university, research institution)  

    Other Link： https://www.ritsumei-arsvi.org/publication/center_report/publication-center25/

  • 家族の形成と解体——不妊クリニックへの通院を経て里子を迎えた養育里親の語りから

    由井秀樹

    生存学研究センター報告   2016.3

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    Authorship：Lead author,　Last author,　Corresponding author   Language：Japanese   Publishing type：Research paper (bulletin of university, research institution)  

    Other Link： https://www.ritsumei-arsvi.org/publication/center_report/publication-center25/

  • 戦前・戦中期東京府における医療施設出産 Reviewed

    由井秀樹

    保健医療社会学論集   2016.2

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    Authorship：Lead author,　Last author,　Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

    Other Link： https://www.jstage.jst.go.jp/article/jshms/26/2/26_43/_article/-char/ja/

  • 書評『近代日本における出産と産屋――香川県伊吹島の出部屋の存続と閉鎖』（伏見裕子著，勁草書房，2016年） Invited

    由井秀樹

    図書新聞   ( 3258 )   4   2016

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    Language：Japanese   Publishing type：(MISC) Book review and document introduction, etc.  

  • 男性不妊の不可視化と母性保護概念――非配偶者間人工授精は誰のための処置だったか？

    由井秀樹

    家族研究年報   2015.9

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    Authorship：Lead author,　Last author,　Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

    Other Link： https://www.jstage.jst.go.jp/article/afs/40/0/40_7/_article/-char/ja

  • Pediatricians' Approach to Child Delivery : Treating Premature Infants Before and During World War II in Japan

    ( 31 )   75 - 81   2015.2( ISSN：1346-678X )

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    Language：Japanese  

    CiNii Books

    Other Link： http://hdl.handle.net/10367/6060

  • 日本における非配偶者間人工授精導入時の法律問題研究——法的父子関係をめぐる議論を中心に

    由井秀樹

    生存学研究センター報告   2014.3

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    Authorship：Lead author,　Last author,　Corresponding author   Language：Japanese   Publishing type：Research paper (bulletin of university, research institution)  

    Other Link： http://www.arsvi.com/b2010/1403km.htm

  • [翻訳]「インドでつくられる」赤ん坊——依頼者の母性と国境を越えた代理懐胎

    カレン・ヴァイトフェルト・メルソン(著)、由井秀樹(訳)

    生存学   ( 7 )   142 - 152   2014.2

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    Language：Japanese   Publishing type：(MISC) Introduction and explanation (others)  

  • 日本における非配偶者間人工授精の導入と産婦人科学における男性不妊研究の展開ーー産婦人科医向け雑誌の分析から Reviewed

    由井秀樹

    科学史研究   2013.12

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    Authorship：Lead author,　Last author,　Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

  • 学校衛生と石原色覚検査表に関する歴史的検討 Reviewed

    由井秀樹

    生存学   2013.3

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    Authorship：Lead author,　Last author,　Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

  • 不妊治療を経て特別養子縁組を選択した患者の経験——特別養子縁組成立までのプロセスに着目して Reviewed

    由井秀樹

    保健医療社会学論集   2013.2

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    Authorship：Lead author,　Last author,　Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

    Other Link： https://www.jstage.jst.go.jp/article/jshms/23/2/23_KJ00009470108/_article/-char/ja/

  • 日本における初の人工授精成功例に関する歴史的考察--医師の言説を中心に Reviewed

    由井秀樹

    コア・エシックス   2012.3

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    Authorship：Lead author,　Last author,　Corresponding author   Language：Japanese   Publishing type：Research paper (bulletin of university, research institution)  

    Other Link： https://ritsumei.repo.nii.ac.jp/?action=pages_view_main&active_action=repository_view_main_item_detail&item_id=5578&item_no=1&page_id=13&block_id=21

  • 非配偶者間人工授精によって出生した人のライフストーリー Reviewed

    立命館人間科学研究   2011.12

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    Other Link： https://ritsumei.repo.nii.ac.jp/?action=pages_view_main&active_action=repository_view_main_item_detail&item_id=4272&item_no=1&page_id=13&block_id=21

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Books and Other Publications

  • 未来を考えるための科学史・技術史入門

    河村豊, 小長谷大介, 山﨑文徳, 但馬亨, 中澤聡, 和田正法, 水沢光, 佐野正博, 永島昂, 由井秀樹（ Role： Joint Work第19章 医学史を通して複雑化する現代の科学・技術を考える）

    北樹出版  2023.4 

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    Language：Japanese  

  • Guidelines for Stem Cell Research and Clinical Translation

    2023.3 

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    Language：Japanese  

  • 科学史事典

    （ Role： Single Work「人工生殖技術」pp.408-409）

    丸善出版  2021.5 

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    Responsible for pages：408-409   Language：Japanese   Book type：Dictionary, encyclopedia

  • 養子縁組の再会と交流のハンドブック

    （ Role： Joint Translation 第3章「捜索の手が書い」pp.37-58、第5章「生父との再会」pp.96-113、第8章「拒絶及び失敗に終わる再会」pp.157-178）

    生活書院  2019.6 

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    Language：Japanese   Book type：Scholarly book

  • 生命倫理の論文・レポートを書く

    （ Role： Joint Work第7章「いまとらえなおすために歴史をふり返る」pp.111-124）

    東京大学出版会  2018.4 

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    Language：Japanese   Book type：Scholarly book

  • テーマでひらく学びの扉 少子化社会と妊娠・出産・子育て

    （ Role： Editor序章 pp.ⅲ-ⅴ、第1章「結婚――誰が子を産み、育てるのか」pp.1-14、第6章「不妊――生殖補助技術は何を問いかけるのか」pp.77-89、終章 pp.142-148）

    北樹出版  2017.4 

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    Language：Japanese   Book type：Scholarly book

  • 人工授精の近代ーー戦後の「家族」と医療・技術

    由井秀樹（ Role： Single Work）

    青弓社  2015.3 

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    Language：Japanese   Book type：Scholarly book

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Presentations

  • [若手論文奨励賞受賞講演] 優生保護法第4条に基づく強制不妊手術対象者の探索――1950年代北海道の保健所の事業からの検討

    由井秀樹

    第36回日本生命倫理学会大会  2024.11 

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    Language：Japanese   Presentation type：Oral presentation(invited, special)  

  • 1980年代から90年代初頭の医学部／医科大学の倫理委員会――自発的設置の背景の検討

    由井秀樹

    第36回日本生命倫理学会大会  2024.11 

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    Language：Japanese   Presentation type：Oral presentation(general)  

  • History of Artificial Insemination and Sperm Donation in Japan Invited

    Hideki Yui

    Third Party Reproduction: Governance, Relatedness & Globalization  2024.10 

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    Event date： 2024.10

    Language：English   Presentation type：Oral presentation(invited, special)  

  • Forced Sterilization and Determination of "Heritability" Under the Eugenic Protection Law

    Hideki Yui

    The 69th Annual Meeting of the Japan Society of Human Genetics  2024.10 

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    Language：English   Presentation type：Poster presentation  

  • Human embryo research and the N-day rule

    Hideki Yui

    IMS Research Seminer  2024.7 

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    Language：English  

  • 研究倫理の制度――現状と課題及びその歴史

    由井秀樹

    第71回日本科学史学会年会 シンポジウム「人を対象とする生命科学・医学研究の倫理の現状と歴史」  2024.5 

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    Language：Japanese  

  • Data collection for large-scale birth cohort studies: Experience from the Japan Environment and Children's Study

    Hideki Yui

    Ethics and Global Governance of Genomic Medicine From the Perspectives of East Asia (Parallel Session of the Tokyo Symposium & Workshop on Genomic Medicine, Therapeutics and Health)  2024.4 

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    Language：English  

  • ヒト胚モデルを作成する研究に関する意識調査の国際比較

    由井秀樹, 八代嘉美, 武藤香織, 渡部沙織, 木屋幸孝, 井上悠輔, 山縣然太朗

    日本生命倫理学会第35回年次大会  2023.12 

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    Language：Japanese  

  • iPS 細胞の備蓄と利活用に関する日本公衆衛生学会員への調査

    由井秀樹, 山縣然太朗

    第82回日本公衆衛生学会総会  2023.10 

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    Language：Japanese  

  • Sterilization policy in post war Japan: Forced sterilization and family planning

    Hideki Yui

    The 8th Association for Asian Study-in-Asia Conference  2023.6 

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    Language：English   Presentation type：Symposium workshop panel(public)  

  • 採血を伴う医学研究に対する小児自身による評価ーー動的プロセスとしてのインフォームド・アセント Invited

    由井秀樹

    第67回医学系大学倫理委員会連絡会議学術集会  2023.6 

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    Language：Japanese   Presentation type：Symposium workshop panel(nominated)  

  • ヒト胚研究ならびに生殖補助医療の論点と日本の規制

    由井秀樹

    第1回 生殖工学研究会 第70回 発生工学研究センターセミナー 発生工学技術開発・実践特別教育プログラム「ARTの基礎・臨床・倫理─未来を見据えて」  2023.5 

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    Language：Japanese  

  • ヒト胚培養の14日ルールに関する倫理的課題――意識調査と質的調査の結果から

    木矢幸孝・原田香菜・由井秀樹・渡部沙織・八代嘉美・武藤香織

    第22回日本再生医療学会総会  2023.3  日本再生医療学会

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    Event date： 2023.3

    Language：Japanese   Presentation type：Oral presentation(general)  

    Venue：国立京都国際会館  

  • Survey of the public in Japan, the US, the UK, Australia and Canada regarding the mitochondrial replacement: A new type of egg donation International conference

    Hideki Yui, Yoshimi Yashiro, Kaori Muto, Saori Watanabe, Yukitaka Kiya, Kumiko Fujisawa, Zentaro Yamagata

    Research seminar: Reconceiving Donor Conception from Perspective of Denmark, Japan, and Taiwan  2023.3 

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    Event date： 2023.3

    Language：English   Presentation type：Public discourse, seminar, tutorial, course, lecture and others  

    Venue：Meiji Gakuin University  

  • 提題ーー何が問題なのか Invited

    由井秀樹

    上智大学生命倫理研究所シンポジウム「出自を知ることの重要性を考える――子ども、親、生物学的親の視点から」  2023.3 

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    Event date： 2023.3

    Language：Japanese   Presentation type：Symposium workshop panel(nominated)  

    Venue：上智大学  

  • 医学研究及びヒト胚研究に関する倫理指針と培養可能期間をめぐる展開

    日本科学史学会第26回西日本研究大会  2022.12 

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    Event date： 2022.12

    Language：Japanese   Presentation type：Oral presentation(general)  

  • 社会的養育の概況

    由井秀樹

    第40回山梨小児保健協会学術集会シンポジウム「社会的養育の現状と課題」  2022.11 

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    Event date： 2022.11

    Language：Japanese   Presentation type：Symposium workshop panel(public)  

  • 幹細胞・胚関連研究に関する研究者・一般市民への大規模意識調査 Invited

    由井秀樹

    公開シンポジウム 「再生医療研究のELSIーーヒト胚研究利用と14日ルール」  2022.11 

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    Event date： 2022.11

    Language：Japanese   Presentation type：Symposium workshop panel(nominated)  

    Venue：オンライン  

  • ヒト胚の培養可能期間をめぐる専門家・一般市民に対する意識調査

    由井秀樹・武藤香織・八代嘉美・渡部沙織・木矢幸孝・藤澤空見子・山縣然太朗

    日本生命倫理学会第34回年次大会  2022.11 

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    Event date： 2022.11

    Language：Japanese   Presentation type：Oral presentation(general)  

    Venue：関西学院大学／オンライン  

  • 幹細胞・胚関連の研究活動に関する日本の現状と課題ーー国際幹細胞学会（ISSCR）ガイドラインとの比較から

    由井秀樹

    2022年度第2回倫理担当者会議（AMED再生医療実現拠点ネットワークプログラム　再生医療の実現化支援課題「再生医療研究とその成果の応用に関する倫理的課題の解決支援」）  2022.9 

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    Event date： 2022.9

    Language：Japanese   Presentation type：Public discourse, seminar, tutorial, course, lecture and others  

    Venue：オンライン開催  

  • Who was the sperm donor in Japan?: A history of Japanese follow-up surveys of children conceived through artificial insemination and sperm banking International conference

    Hideki Yui

    Reconceiving Donor Conception: What are the current challenges and possibilities of responsible donor conception?  2022.8 

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    Event date： 2022.8

    Language：English   Presentation type：Public discourse, seminar, tutorial, course, lecture and others  

    Venue：Aalborg University (Copenhagen)  

  • Who was the sperm donor in Japan?: A history of Japanese follow-up surveys of children conceived through artificial insemination and sperm banking Invited

    Hideki Yui

    Reconceiving Donor Conception: What are the current challenges and possibilities of responsible donor conception?  2022.8 

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    Language：English   Presentation type：Oral presentation(general)  

  • 日本の文脈における胎児組織研究の争点 Invited

    由井秀樹

    京都大学CiRA・ASHBi生命倫理研究会  2022.6 

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    Event date： 2022.6

    Language：Japanese   Presentation type：Public discourse, seminar, tutorial, course, lecture and others  

  • Patient and public involvement/engagement (PPI/E) and benefit-sharing in stem cell research: A survey towards patients in Japan International conference

    Saori Watanabe, Kaori Muto, Hideki Yui, Zentaro Yamagata, Yoshimi Yashiro

    International Society for Stem Cell Research 2022 Annual Meeting  2022.6 

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    Event date： 2022.6

    Language：English   Presentation type：Poster presentation  

  • Survey of the attitudes of the general public and patients in Japan toward research involving the culture of human embryos beyond 14 days International conference

    Hideki Yui, Kaori Muto, Yoshimi Yashiro, Saori Watanabe, Zentaro Yamagata

    International Society for Stem Cell Research 2022 Annual Meeting  2022.6 

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    Event date： 2022.6

    Language：English   Presentation type：Poster presentation  

  • Healthy children’s assessments of their experiences of blood collection with topical anesthesia International conference

    Hideki Yui, Kaori Muto, Zentaro Yamagata

    European Society of Human Genetics conference 2022  2022.6 

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    Event date： 2022.6

    Language：English   Presentation type：Poster presentation  

  • 優生保護法のもとでの本人意思に基づく不妊手術ーー家族計画と不妊手術

    由井秀樹

    日本保健医療社会学会第48回大会  2022.5 

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    Language：Japanese   Presentation type：Oral presentation(general)  

  • 新型コロナウイルス流行下における子どもの孤立感に関係する背景要因の検討

    久島萌，堀内清華，篠原亮次，由井秀樹，大岡忠生，小島令嗣，秋山有佳，横道洋司，山縣然太朗，小田和早苗

    第80回日本公衆衛生学会総会  2021.12 

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    Event date： 2021.12

    Language：Japanese   Presentation type：Poster presentation  

    Venue：京王プラザホテル・東京大学伊藤国際学術研究センター  

  • コロナ禍を経験した社会における再生医療・異種移植をめぐる公衆衛生上の問題

    由井秀樹, 山縣然太朗

    第80回日本公衆衛生学会総会  2021.12 

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    Event date： 2021.12

    Language：Japanese   Presentation type：Poster presentation  

    Venue：オンライン/ 京王プラザホテル  

  • 新型コロナウイルス流行下における子どものQOLと影響因子：エコチやまなし追加調査

    堀内清華，篠原亮次，久島萌，小田和早苗，由井秀樹，大岡忠生，小島令嗣，秋山有佳，横道洋司，山縣然太朗

    第80回日本公衆衛生学会総会  2021.12 

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    Event date： 2021.12

    Language：Japanese   Presentation type：Oral presentation(general)  

    Venue：京王プラザホテル・東京大学伊藤国際学術研究センター  

  • 新型コロナウイルス流行下における子どもの QOLと影響因子――エコチルやまなし追加調査

    堀内清華, 篠原亮次, 久島萌, 小田和早苗, 由井秀樹, 大岡忠生, 小島令嗣, 秋山有佳, 横道洋司, 山縣然太朗

    日本公衆衛生学会第80回総会  2021.12 

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    Language：Japanese  

  • ヒト胎児組織を用いる研究をめぐる近年のアメリカの動向

    由井秀樹・山縣然太朗

    日本生命倫理学会第33回年次大会  2021.11 

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    Event date： 2021.11

    Language：Japanese   Presentation type：Oral presentation(general)  

    Venue：オンライン開催  

  • 戦後日本における男性不妊の語られ方 Invited

    由井秀樹

    お茶の水女子大学ジェンダー研究所IGFセミナー「不妊と男性のセクシュアリティ」  2021.11 

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    Event date： 2021.11

    Language：Japanese   Presentation type：Public discourse, seminar, tutorial, course, lecture and others  

    Venue：オンライン開催  

  • コロナ禍の子どもたちへの影響～エコチルやまなし追加調査より～

    堀内清華，篠原亮次，小田和早苗，久島萌，由井秀樹，秋山有佳，大岡忠生，小島令嗣，横道洋司，三宅邦夫，山縣然太朗

    第39回山梨県小児保健協会学術集会  2021.11 

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    Event date： 2021.11

    Language：Japanese   Presentation type：Oral presentation(general)  

    Venue：山梨大学医学部キャンパス  

  • 精子提供をめぐる論点 ーー日本における非配偶者間人工授精の過去の実施状況、議論から Invited

    由井秀樹

    第40回　日本医学哲学倫理学会・シンポジウム「AID（DI）の倫理ーー出自を知る権利をめぐるこれまでの議論の経緯と今後の課題」  2021.11 

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    Event date： 2021.11

    Language：Japanese   Presentation type：Symposium workshop panel(nominated)  

    Venue：横浜市立大学  

  • Human Fetal Tissue Research and Abortion Dispute in Japan: Comparison to the Recent Situation in the US International conference

    Hideki Yui, Zentaro Yamagata

    International Society for Stem Cell Research 2021 Annual Meeting  2021.6 

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    Event date： 2021.6

    Language：English   Presentation type：Poster presentation  

  • ヒト胎児組織の研究利用のガバナンスーーヒト幹細胞を用いた臨床研究の在り方に関する専門委員会における議論の分析から

    由井秀樹

    日本科学史学会第68回年会  2021.5 

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    Event date： 2021.5

    Language：Japanese   Presentation type：Oral presentation(general)  

  • A Study of Donor Protection in Donor Conception: The History of Sperm Donation in Japan

    Hideki Yui

    Joint Atlantic Seminar in East Asian Science, Technology, and Medicine  2021.4 

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    Event date： 2021.4

    Language：English   Presentation type：Oral presentation(general)  

  • The History of Japanese Follow-up Surveys of Children Conceived by Artificial Insemination by Donor (AID)

    Hideki Yui

    European Association for the Study of Science and Technology/ Society for Social Studies of Science 2020 Conference  2020.8 

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    Language：English   Presentation type：Oral presentation(general)  

  • 不妊治療、ARTの歴史――フォローアップ調査に着目して Invited

    由井秀樹

    第17回日本生殖心理学会学術集会  2020.2 

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    Language：Japanese   Presentation type：Oral presentation(invited, special)  

  • 生殖をめぐる「計画」の啓発――「ライフプラン」教育の前史としての「家族計画」教育

    由井 秀樹

    日本家族社会学会第29回大会  2019.9 

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    Language：Japanese  

  • 母子保健の近現代（ラウンドテーブルディスカッション）

    由井秀樹, 伏見裕子, 松島京, 木村尚子, 笹谷絵里

    日本保健医療社会学会第45回大会  2019.5 

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    Language：Japanese  

  • 「科学的知識」としての「適正な」生殖年齢の啓発をめぐる近現代史

    由井 秀樹

    第22回科学史西日本研究大会  2018.12 

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    Language：Japanese  

  • The measures to raise fertility rates and maternal and child health policy in Japan: “Appropriate” age for reproduction

    YUI Hideki

    Population and Reproduction in Japan: From the Perspective of Global History Workshop  2018.8 

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    Language：English  

  • 不妊治療、ARTの歴史 Invited

    由井 秀樹

    2018年度ナースのためのART医学セミナー学術集会  2018.5 

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    Language：Japanese  

  • 公募ワークショップ 生命倫理教育において“何を”“どう”書かせるのか?――生命倫理学における知的生産技術の再検討とその伝授

    伊吹友秀, 土屋敦, 堀田義太郎, 由井秀樹

    日本生命倫理学会第29回年次大会  2017.12 

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    Language：Japanese  

  • 戦前・戦中期京都市における出生介助状況

    由井 秀樹

    第21回科学史西日本研究大会  2017.12 

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    Language：Japanese  

  • 日本におけるAIDの歴史 Invited

    由井秀樹

    勉強会「AIDで生まれた人の出自を知る権利を保障する」  2017.9 

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    Language：Japanese  

  • 「健やか親子21」以降の母子保健政策における不妊対策の展開

    由井 秀樹

    第27回日本家族社会学会大会  2017.9 

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    Language：Japanese  

  • Teaching the 'Correct' Way to Marry and Reproduce: The Government's Attempt to Rise Birth Rate in Japan

    YUI Hideki

    UK-Japan Seminar on the Politics and Practices of ‘Low-Fertility and Ageing Population’ in Post-War Japa  2017.1 

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    Language：English  

  • 戦後日本の代理懐胎――読売新聞『人生案内』の分析（1949-1975）

    由井 秀樹

    第28回日本生命倫理学会年次大会  2016.12 

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    Language：Japanese  

  • 戦後日本の身上相談にみる不妊事例

    第26回日本家族社会学会大会  2016.9 

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    Language：Japanese  

  • 公募ワークショップ「生殖と医療をめぐる現代史研究と生命倫理」

    第27回日本生命倫理学会年次大会  2015.11 

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    Language：Japanese  

  • 日本における体外受精研究黎明期の分野横断型共同研究

    日本科学史学会第62回年会・総会  2015.5 

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    Language：Japanese  

  • 戦前・戦中期日本の都市部における出産の施設化 ーー東京の低所得者向け産院、産院を前身とする病院における分娩取扱状況の分析

    第41回日本保健医療社会学会大会  2015.5 

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    Language：Japanese  

  • A Historical Study on Life-saving Intervention for Premature Infants and Maternal & Child Health Policy in Japa

    HEALTH POLICY AND POLITICS IN DIVERSIFYING SOCIETIES: ASIAN AND GLOBAL ISSUES Conference  2014.11 

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    Language：English  

  • 日本における不妊医療研究の系譜

    日本生命倫理学会第26回年次大会  2014.10 

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    Language：Japanese  

  • 明治期から戦後初期の医学的言説における人工授精

    日本家族社会学会第24回大会  2014.9 

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    Language：Japanese  

  • 男性不妊の不可視化と母性保護概念：非配偶者間人工授精は誰のための処置だったのか？

    家族問題研究学会2014年大会シンポジウム「生殖補助医療と家族」  2014.7 

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    Language：Japanese  

  • 戦時人口政策と不妊症研究、及び産婦人科医学者集団の動向

    第17回科学史西日本研究大会  2013.12 

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    Language：Japanese  

  • 家族計画と人工授精——1940年代後半から1950年代にかけての展開

    第23回日本家族社会学会大会  2013.9 

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    Language：Japanese  

  • 日本における人工授精普及過程に関する歴史的検討——「生殖の医療化の進展」

    第39回日本保健医療社会学会大会  2013.5 

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    Language：Japanese  

  • 配偶子提供、代理懐胎における「子の福祉」－－AID出生者の事例から

    日本生命倫理学会第24回年次大会  2012.10 

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    Language：Japanese  

  • 日本における人工授精史の検討

    日本科学史学会西日本2011年度中国支部年会・第15回西日本研究大会  2011.11 

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    Language：Japanese  

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Awards

  • 若手論文奨励賞

    2024.11   日本生命倫理学会  

  • 2015年度日本科学史学会学術奨励賞

    2016.5   日本科学史学会  

Teaching Experience

  • 薬学部1年生と学ぶ倫理学

    2024.9
    Institution：昭和薬科大学

  • 衛生学・公衆衛生学

    2024.9
    Institution：山梨県歯科衛生専門学校

  • 健康とは、疾病とは

    2023.10
    Institution：甲府医療秘書学院

  • 患者論と医療倫理

    2023.10
    Institution：甲府医療秘書学院

  • 現代科学の展開

    2021.4
    -
    2021.9
    Institution：関西大学

  • 生命科学と倫理

    2018.9
    -
    2020.3
    Institution：立命館大学

  • 福祉事業論

    2018.9
    -
    2019.3
    Institution：甲南大学

  • 自然科学史Ⅱ

    2018.4
    -
    2020.9
    Institution：龍谷大学

  • 福祉社会学Ⅱ

    2017.9
    -
    2018.3
    Institution：神戸学院大学

  • 家族福祉論

    2016.9
    -
    2022.3
    Institution：京都府立大学

  • プロジェクト予備演習

    2016.4
    -
    2017.3
    Institution：立命館大学大学院

  • 児童福祉論Ⅱ

    2015.9
    -
    2016.9
    Institution：京都府立大学

  • 倫理学

    2015.4
    -
    2017.3
    Institution：明治東洋医学院専門学校

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Social Activities

  • 生殖への国家介入 今議論を（親子の新たな物語17 精子提供と家族のかたち）

    Role(s)： Media coverage

    信濃毎日新聞  2022.2

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    Audience： General

    Type：Newspaper, magazine

Professional Memberships

  • 日本科学史学会

  • 日本生命倫理学会

  • 日本保健医療社会学会

  • 日本公衆衛生学会

  • 日本家族社会学会

  • 日本科学史学会

  • 日本生命倫理学会

  • 日本家族社会学会

  • 日本公衆衛生学会

  • 日本保健医療社会学会

  • 科学技術社会論学会

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Committee Memberships

  • 日本生命倫理学会   研究開発委員  

    2024.3   

  • 日本生命倫理学会   国際交流委員会委員  

    2024.1   

  • 日本科学史学会   全体委員会委員  

    2023.5   

  • 日本科学史学会   普及委員会委員  

    2023.2   

  • 日本公衆衛生学会   第81回総会学術部会委員  

    2021.10   

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    Committee type：Society

  • 日本公衆衛生学会   第81回総会学術部会委員  

    2021.10 - 2022.10   

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    Committee type：Society

  • 上尾中央綜合病院新規医療技術・医薬品等評価委員会   外部委員  

    2020.7   

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    Committee type：Others

  • 上尾中央総合病院新規医療技術・医薬品等評価委員会   外部委員  

    2020.7   

  • 日本科学史学会   和文誌編集委員会委嘱委員  

    2019.6   

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    Committee type：Society

  • 日本科学史学会   和文誌編集委員会委嘱委員  

    2019.6   

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    Committee type：Society

  • 日本保健医療社会学会   機関紙編集委員会査読委員  

    2018.10 - 2019.3   

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    Committee type：Society

  • 日本科学史学会   第63回年会準備委員  

    2016.2 - 2016.5   

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    Committee type：Society

  • HEALTH POLICY AND POLITICS IN DIVERSIFYING SOCIETIES : ASIAN AND GLOBAL ISSUES CONFERENCE   事務局  

    2014.5 - 2014.11   

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    Committee type：Society

  • 日本生命倫理学会   第24回年次大会事務局  

    2012.4 - 2012.10   

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    Committee type：Society

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