Association of Circadian Clock Gene Expression with Pediatric/Adolescent Asthma and Its Comorbidities Reviewed

Nguyen Quoc Vuong Tran, Minh-Khang Le, Thuy-An Nguyen, Tetsuo Kondo, Atsuhito Nakao

International Journal of Molecular Sciences   24 ( 8 )   7477   2023.4( ISSN：1422-0067 )

Welcome to "Circadian Immunology & Allergology": Why timing matters in diagnosing and treating allergies Reviewed

Atsuhito Nakao

ALLERGOLOGY INTERNATIONAL   71 ( 4 )   423 - 424   2022.10( ISSN：1323-8930 )

Time will tell about mast cells: Circadian control of mast cell activation Reviewed

Atsuhito Nakao, Yuki Nakamura

ALLERGOLOGY INTERNATIONAL   71 ( 4 )   425 - 431   2022.10( ISSN：1323-8930 )

時間医学の観点から考慮した方がいい薬剤処方がありますか？

中尾　篤人

JOHNS   38 ( 9 )   1151 - 1154   2022.9

アレルギー疾患と概日リズム

中尾　篤人

医学のあゆみ   281 ( 2 )   175 - 179   2022.4

睡眠障害による慢性蕁麻疹の悪化 Major achievement

中尾　篤人

Visual Dermatology   21 ( 3 )   282 - 283   2022.3

時計じかけのアレルギー Major achievement

中尾　篤人

アレルギー   71 ( 1 )   22 - 26   2022.2

Probiotic Supplementation and Human Milk Cytokine Profiles in Japanese Women: A Retrospective Study from an Open-Label Pilot Study Reviewed

Takahashi T, Fukudome H, Ueno HM, Watanabe-Matsuhashi S, Nakano T, Kobayashi T, Ishimaru K, Nakao A

Nutrients   13 ( 7 )   2285   2021.6

脳内報酬系の活性化はアレルギーを緩和する

中尾　篤人

医学のあゆみ   277 ( 13 )   1123   2021.6

アレルギーと概日時計

中尾　篤人

日本小児アレルギー学会誌   35 ( 1 )   1 - 7   2021.3

脳内ドーパミン報酬系の活性化による皮膚アレルギー反応の抑制

中尾　篤人

臨床免疫・アレルギー科   75 ( 3 )   307 - 310   2021.3

花粉症の免疫学

中尾　篤人

診断と治療   109 ( 2 )   173 - 176   2021.2

Activation of the reward system ameliorates passive cutaneous anaphylactic reaction in mice. Reviewed

Nakajima S, Manita S, Yu G, Ishimaru K, Kono K, Kitamura K, Nakao A

ALLERGY   75 ( 12 )   3275 - 3279   2020.12( ISSN：0105-4538 )

IL-33によるマスト細胞活性化とアレルギー

中尾　篤人

臨床免疫・アレルギー科   74 ( 5 )   484 - 488   2020.11

Circadian Regulation of the Biology of Allergic Disease: Clock Disruption Can Promote Allergy. Reviewed

Nakao A

Frontiers in Immunology   11   1237   2020.6( ISSN：1664-3224 )

A first case of meningitis/encephalitis associated with SARS-Coronavirus-2. Reviewed

Moriguchi T, Harii N, Goto J, Harada D, Sugawara H, Takamino J, Ueno M, Sakata H, Kondo K, Myose N, Nakao A, Takeda M, Haro H, Inoue O, Suzuki-Inoue K, Kubokawa K, Ogihara S, Sasaki T, Kinouchi H, Kojin H, Ito M, Onishi H, Shimizu T, Sasaki Y, Enomoto N, Ishihara H, Furuya S, Yamamoto T, Shimada S

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES   94   55 - 58   2020.5( ISSN：1201-9712 )

Commensal-bacteria-derived butyrate promotes the T cell-independent IgA response in the colon. Reviewed

Isobe J, Maeda S, Obata Y, Iizuka K, Nakamura Y, Fujimura Y, Kimizuka T, Hattori K, Yun-Gi Kim, Morita T, Kimura I, Offermanns S, Adachi T, Nakao A, Kiyono H, Takahashi D, Hase K

INTERNATIONAL IMMUNOLOGY   32 ( 4 )   243 - 258   2020.4( ISSN：0953-8178 )

Time-restricted feeding in rest phase alters IgE/mast cell–mediated allergic reaction in mice. Reviewed

Nakamura Y, Ishimaru K, Nakao A

ALLERGOLOGY INTERNATIONAL   69 ( 2 )   296 - 299   2020.4( ISSN：1323-8930 )

The Putatively Specific Synthetic REV-ERB Agonist SR9009 Inhibits IgE- and IL-33-Mediated Mast Cell Activation Independently of the Circadian Clock. Reviewed

Ishimaru K, Nakajima S, Yu G, Nakamura Y, Nakao A

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   20 ( 24 )   6320   2019.12( ISSN：1422-0067 )

Resveratrol inhibits IL-33–mediated mast cell activation by targeting the MK2/3–PI3K/Akt axis. Reviewed

Nakajima S,Ishimaru K, Kobayashi A, Guannan Yu, Nakamura Y, Oh-oka K, Suzuki-Inoue K, Kono K, Nakao A

Scientific Reports   9 ( 1 )   18423   2019.12( ISSN：2045-2322 )

Snake venom rhodocytin induces plasma extravasation via toxin-mediated interactions between platelets and mast cells. Reviewed

Nakamura Y, Sasaki T, Mochizuki C, Ishimaru K, Koizumi S, Shinmori H, Suzuki-Inoue K, Nakao A

Scientific Reports   9 ( 1 )   15958   2019.11( ISSN：2045-2322 )

Effects of Probiotic Supplementation on TGF-β1, TGF-β2, and IgA Levels in the Milk of Japanese Women: An Open-Label Pilot Study. Reviewed

Takahashi T, Fukudome H, Hiroshi M. Ueno, Watanabe-Matsuhashi S, Nakano T, Kobayashi T, Ishimaru K, Nakao A

frontiers in Nutrition   6   128   2019.9

Intermittent restraint stress induces circadian misalignment in the mouse bladder, leading to nocturia. Reviewed

Ihara T, Nakamura Y, Mitsui T, Tsuchiya S, Kanda M, Kira S, Nakagomi H, Sawada N, Kamiyama M, Shigetomi E, Shinozaki Y, Yoshiyama M, Nakao A, Koizumi S, Takeda M

Scientific Reports   9 ( 1 )   10069   2019.7( ISSN：2045-2322 )

免疫療法と体内時計

中尾　篤人

チャイルドヘルス   22 ( 7 )   43 - 45   2019.7

Establishment of enzyme-linked immunosorbent facilitated antigen binding as a biomarker assay for Japanese cedar pollen allergy immunotherapy. Reviewed

Fukano C, Ohashi-Doi K, Lund K, Nakao A, Masuyama K, Matsuoka T

JOURNAL OF PHARMACOLOGICAL SCIENCES   140 ( 3 )   223 - 227   2019.7( ISSN：1347-8613 )

時計じかけのアレルギー　概日時計によるアレルギー制御

中尾　篤人

生体の科学   70 ( 2 )   87 - 91   2019.4

Clockwork Allergy:How the Circadian Clock Underpins Allergic Reactions. Reviewed

Nakao A

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY   142 ( 4 )   1021 - 1031   2018.10( ISSN：0091-6749 )

The time-dependent variation of ATP release in mouse primary-cultured urothelial cells is regulated by the clock gene. Reviewed

Ihara T, Mitsui T, Nakamura Y, Kanda M, Tsuchiya S, Kira S, Nakagomi H, Sawada N, Kamiyama M, Shigetomi E, Shinozaki Y, Yoshiyama M, Nakao A, Takeda M, Koizumi S

NEUROUROLOGY AND URODYNAMICS   37 ( 8 )   2535 - 2543   2018.8( ISSN：0733-2467 )

時計遺伝子と免疫疾患

中尾　篤人

炎症と免疫   26 ( 5 )   50 - 54   2018.8

サーカディアンリズムとアレルギー―とくにマスト細胞活性化を中心として

中尾　篤人

医学のあゆみ   265 ( 9 )   789 - 792   2018.6

The oscillation of intracellular Ca2+ influx associated with the circadian expression of Piezo1 and TRPV4 in the bladder urothelium. Reviewed

Ihara T, Mitsui T, Nakamura Y, Kanda M, Tsuchiya S, Kira S, Nakagomi H, Sawada N, Kamiyama M, Hirayama Y, Shigetomi E, Shinozaki Y, Yoshiyama M, Nakao A, Takeda M, Koizumi S

Scientific Reports   8 ( 1 )   5699   2018.4( ISSN：2045-2322 )

サーカディアンリズムとアレルギー

中尾　篤人

臨床免疫・アレルギー科   69 ( 4 )   402 - 406   2018.4

The Circadian expression of Piezo1, TRPV4, Connexin26, and VNUT, associated with the expression levels of the clock genes in mouse primary cultured urothelial cells. Reviewed

Ihara T, Mitsui T, Nakamura Y, Kanda M, Tsuchiya S, Kira S, Nakagomi H, Sawada N, Hirayama Y, Shibata K, Shigetomi E, Shinozaki Y, Yoshiyama M, Nakao A, Takeda M, Koizumi S

NEUROUROLOGY AND URODYNAMICS   37 ( 3 )   942 - 951   2018.3( ISSN：0733-2467 )

アレルギーの時間医学

中尾　篤人

Medical Science Digest   44 ( 1 )   16 - 19   2018.1

Differential Day–Night Outcome to HSV-2 Cutaneous Infection. Reviewed

Matsuzawa T, Nakamura Y, Ogawa Y, Ishimaru K, Goshima F, Shimada S, Nakao A, Kawamura T

JOURNAL OF INVESTIGATIVE DERMATOLOGY   138 ( 1 )   233 - 236   2018.1( ISSN：0022-202X )

The frequency of Th17 cells in the small intestine exhibits a dayenight variation dependent on circadian clock activity. Reviewed

Thu Le HP, Nakamura Y, Oh-oka K, Ishimaru K, Nakajima S, Nakao A

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   490 ( 2 )   290 - 295   2017.8( ISSN：0006-291X )

Circadian clock-dependent increase in salivary IgA secretion modulated by sympathetic receptor activation in mice. Reviewed

Wada M, Orihara K, Kamagata M, Hama K, Sasaki H, Haraguchi A, Miyakawa H, Nakao A, Shibata S

Scientific Reports   ( 7 )   8802   2017.8( ISSN：2045-2322 )

Clock-dependent temporal regulation of IL-33/ST2-mediated mast cell response. Reviewed

Kawauchi T*, Ishimaru K*, Nakamura Y, Nakano N, Hara M, Ogawa H, Okumura K, Shibata S, Nakao A (*Thease authers contributed equally to this work.)

ALLERGOLOGY INTERNATIONAL   66 ( 3 )   472 - 478   2017.7( ISSN：1323-8930 )

概日時計を標的としたⅠ型アレルギー反応の制御

中尾　篤人

臨床免疫・アレルギー科   68 ( 1 )   6 - 10   2017.7

Clock-dependent temporal regulation of IL-33/ST2-mediated mast cell response. Reviewed

Nakamura Y, Ishimaru K, Nakao A

ALLERGOLOGY INTERNATIONAL   66 ( 3 )   472 - 478   2017.7( ISSN：1323-8930 )

Induction of colonic regulatory T cells by 5-aminosalicylic acid (5-ASA) by activating the aryl hydrocarbon receptor. Reviewed

Oh-oka K, Kojima Y, Uchida K, Yoda M, Ishimaru K, Nakajima S, Hemmi J, Kano H, Fujii-Kuriyama Y, Katoh R, Ito H, Nakao A

Cell Mol Gastroenterol Hepatol   4 ( 1 )   135 - 151   2017.4

The Clock mutant mouse is a novel experimental model for nocturia and nocturnal polyuria. Reviewed Major achievement

Ihara T, Mitsui T, Kira S, Miyamoto T, Sawada N, Nakagomi H, Yoshiyama M, Takeda M, Nakamura Y, Nakao A, Shinozaki Y, Koizumi S

NEUROUROLOGY AND URODYNAMICS   36 ( 4 )   1034 - 1038   2017.4( ISSN：0733-2467 )

Clock Genes Regulate the Circadian Expression on Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa Reviewed

Ihara T, Mitsui T, Nakamura Y, Kira S, Nakagomi H, Sawada N, Hirayama Y, Shibata K, Shigetomi E, Shinozaki Y, Yoshiyama M, Andersson KE, Nakao A, Takeda M, Koizumi S

PLoS One   12 ( 1 )   1 - 17   2017.1( ISSN：1932-6203 )

Regulation of plasma histamine levels by the mast cell clock and its modulation by stress. Reviewed Major achievement

Yuki NAKAMURA,Kayoko ISHIMARU,Shigenobu SHIBATA,Atsuhito NAKAO

Scientific Reports   7   39934   2017.1( ISSN：2045-2322 )

The Efficacy of Sublingual Immunotherapy for Allergic Rhinitis May Vary with the Time of Day. Reviewed Major achievement

Satoshi IGARASHI,Yuki NAKAMURA,Kayoko ISHIMARU,Keisuke MASUYAMA,Atsuhito NAKAO

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY   171 ( 2 )   111 - 118   2016.12( ISSN：1018-2438 )

花粉症と概日時計 Major achievement

実験医学   34 ( 18 )   2990 - 2995   2016.11

アレルギー克服への期待と興奮 Major achievement

実験医学   34 ( 18 )   2968 - 2973   2016.11

体内時計を標的としてアレルギー症状を緩和する Major achievement

小児科診療   79 ( 10 )   1367 - 1371   2016.10

The alarmin IL-33 derived from HSV-2-infected keratinocytes triggers mast cell-mediated antiviral innate immunity. Reviewed

Aoki R, Kawamura T, Goshima F, Ogawa Y, Nakae S, Moriishi K, Nakao A, Shimada S

JOURNAL OF INVESTIGATIVE DERMATOLOGY   136 ( 6 )   1290 - 1292   2016.6( ISSN：0022-202X )

Synergistic antitumor effect with indoleamine 2,3-dioxygenase inhibition and temozolomide in a murine glioma model Reviewed

Mitsuto HANIHARA,Tomoyuki KAWATAKI,Kyoko Oh-oka,Kentaro MITSUKA,Atsuhito NAKAO,Hiroyuki KINOUCHI

JOURNAL OF NEUROSURGERY   4   1 - 8   2016.6( ISSN：0022-3085 )

Inhibition of IgE-mediated allergic reactions by pharmacologically targeting the circadian clock. Reviewed Major achievement

Yuki NAKAMURA,Nakano N,Kayoko ISHIMARU,Noriko Ando,Ryohei KATOH,Katsue SUZUKI-INOUE,Koyanagi S,Ogawa H,Okumura K,Shibata S,Atsuhito NAKAO

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY   137 ( 4 )   1226 - 1235   2016.4( ISSN：0091-6749 )

Clock遺伝子変異マウスは、夜間頻尿/夜間多尿の新しい実験モデルである Major achievement

井原　達矢,吉良　聡,山岸　敬,宮本　達也,澤田　智史,芳山　充晴,武田　正之,中村　勇規,中尾　篤人

ICS 2015 REPORT(The 45th Annual Meeting of International Continence Society 6-9 October 2015, Montre   6   2016.3

ClockによるIL-33/ST2シグナルの時間依存的な制御 Major achievement

臨床免疫・アレルギー科   65 ( 3 )   229 - 232   2016.3

Synergistic anti-tumor effect with indoleamine 2,3-dioxygenase inhibition and temozolomide in a murine glioma model. Reviewed

Hanihara M1, Kawataki T1, Oh-Oka K2, Mitsuka K1, Nakao A2, Kinouchi H1.

JOURNAL OF NEUROSURGERY   124 ( 6 )   1594 - 1601   2016.1( ISSN：0022-3085 )

Establishment of a therapeutic anti-pan HLA-class Ⅱ monoclonal antibody that directly induces lymphoma cell death via large pore formation. Reviewed

Matsuoka S, Ishii Y, Nakao A, Abe M, Ohtsuji N, Momose S, Jin H, Arase H, Sugimoto K, Nakauchi Y, Masutani H, Maeda M, Yagita H, Komatsu N, Hino O:

PLoS One   11 ( 3 )   e0150496   2016( ISSN：1932-6203 )

Circadian Gene Clock Regulates Psoriasis-Like Skin Infammation in Mice Reviewed Major achievement

Noriko Ando,Yuki NAKAMURA,Rui Aoki,Kayoko ISHIMARU,Hideoki Ogawa,Ko Okumura,Shigenobu Shibata,Shinji Shimada,Atsuhito NAKAO

Journal of Investigative Dermatology   135 ( 12 )   3001 - 3008   2015.12

敗血症の概念,疫学,診断,治療 Major achievement

山梨医科学雑誌   30 ( 2 )   37 - 45   2015.11

時計遺伝子Clockにより制御されるマスト細胞活性化 Major achievement

64 ( 5 )   442 - 446   2015.11

時計遺伝子とアレルギー性炎症 Major achievement

呼吸と循環   63 ( 10 )   951 - 956   2015.10

Antigen exposure in the late light period induces severe symptoms of food allergy in an OVA-allergic mouse model. Reviewed Major achievement

Kana Tanabe,Eri Kitagawa,Misaki Wada,Atsushi Haraguchi,Kanami Orihara,Yu Tahara,Atsuhito NAKAO,Shigenobu Shibata

Scientific Reports   ( 5 )   14424   2015.9

IL-7:AhR We Ready for a New Cytokine to Fight Colitis? Reviewed Major achievement

Atsuhito NAKAO

Dig Dis Sci   60 ( 7 )   1876 - 1877   2015.7

Positive association between serum thymic stromal lymphopoietin and anti-citrullinated peptide antibodies in patients with rheumatoid Reviewed Major achievement

Kensuke KOYAMA,Tetsuroh OHBA,Hirotaka HARO,Atsuhito NAKAO

Clinical Exp Immunol   181 ( 2 )   239 - 243   2015.7

スギ花粉症患者好塩基球反応性の日内変動 Reviewed Major achievement

安藤　典子,島田　眞路,中尾　篤人

臨床免疫・アレルギー科   64 ( 5 )   464 - 467   2015.5

The Circadian Clock Functions As A Potent Regulator of Allergic Reaction. [Review] Reviewed Major achievement

Atsuhito NAKAO,Yuki NAKAMURA,Shibata S

Allergy   70 ( 5 )   467 - 473   2015.5

Allergen-specific basophil reactivity exhibits daily variations in seasonal allergic rhinitis Reviewed Major achievement

Noriko Ando,Yuki NAKAMURA,Kayoko ISHIMARU,Ogawa H,Okumura K,Shinji Shimada,Atsuhito NAKAO

Allergy   70 ( 3 )   319 - 322   2015.3

アレルギーと時計遺伝子 Major achievement

中尾　篤人

臨床免疫・アレルギー科   63 ( 1 )   68 - 72   2015.1

TSLPを介したアレルギー性炎症のメカニズム。 Major achievement

中尾　篤人,久保允人

実験医学増刊 炎症   32 ( 17 )   2791 - 2795   2014.11

Comparison of colostrum TGF-β2 levels between lactating women in Japan and Nepal Reviewed Major achievement

Asian Pacific Journal of Allergy and Immunology   32 ( 2 )   178 - 184   2014.6

Comparison of colostrum TGF-β2 levels between lactating women in Japan and Nepal. Reviewed

Aihara Y,Oh-oka K,Kondo N,Ishimaru K,Hara M,Yamagata Z,Nakao A

Asian Pacific Journal of Allergy and Immunology   32 ( 2 )   2014.6

アレルゲン免疫療法の作用機序の基礎。 Major achievement

中尾　篤人

アレルギー・免疫   21 ( 7 )   1044 - 1049   2014.6

Expressions of tight junction proteins Occludin and Claudin-1 are under the circadian control in the mouse large intestine: implications in intestinal permeability and susceptibility to colitis Reviewed Major achievement

Oh-oka　kyouko,Hiroshi KONO,Kayoko ISHIMARU,Kunio MIYAKE,Takeo KUBOTA,Ogawa H,Okumura K,Shibata S,Atsuhito NAKAO

PLoS One   9 ( 5 )   e98016   2014.5

Identification of a probiotic bacteria-derived activator of the aryl hydrocarbon receptor that inhibits colitis Reviewed Major achievement

Fukumoto S,Maruyama A,Kyoko Oh-oka,Takeyuki TAKAMURA,Yuki NAKAMURA,Kayoko ISHIMARU,Atsuhito NAKAO

Immunology and Cell Biology   92 ( 5 )   460 - 465   2014.5

Temporal regulation of cytokines by the circadian Reviewed Major achievement

Atsuhito NAKAO

Journal of Immunology Research   614529   2014.4

Temporal regulation of cytokines by the circadian clock. Reviewed

Nakao A

Journal of Immunology Research   2014   2014.4

Disruption of the Suprachiasmatic Nucleus Blunts A Time of Day-Dependent Variation in Systemic Anaphylactic Reaction in Mice. Reviewed Major achievement

Yuki NAKAMURA,Kayoko ISHIMARU,Atsuhito NAKAO,Tahara Y,Shibata S

Journal of Immunology Research   474217   2014.4

Residential Area, Birth Order, and Dietary Habit May Influence TSLP Levels in Colostrum: Comparative Study between Japan and Nepal. Reviewed Major achievement

Yoko AIHARA,Naoki KONDO,Jyoti SHARMA,Narayan C SHRESTHA,Kayoko ISHIMARU,Hara mutuko,Zentaro YAMAGATA,Atsuhito NAKAO,Kyoko Oh-oka

Allergology International   63   283 - 285   2014.3

体内時計は花粉症を制御するカギの一つ Major achievement

Medical View Point   35 ( 3 )   12 - 12   2014.3

Circadian regulation of allergic reaction by the mast cell clock in mice. Reviewed Major achievement

Yuki NAKAMURA,Nobuhiro NAKANO,Kayoko ISHIMARU,Mutsuko HARA,Takako IKEGAMI,Atsuhito NAKAO

J Allergy Clin Immun   133 ( 2 )   568 - 575.e12   2014.2

蕁麻疹とアナフィラキシー Major achievement

日本臨牀   71 ( 12 )   2153 - 2157   2013.12

アレルギーに対する免疫療法 Major achievement

実験医学   61 ( 17 )   2885 - 2889   2013.11

Mast Cells Play a Key Role in Host Defence against Herpes Simplex Virus Infection through TNF-α and IL-6 Production Reviewed Major achievement

Rui Aoki,Tatsuyoshi Kawamura,Fumi Goshima,Youichi Ogawa,Susumu Nakae,Atsuhito NAKAO,Kohji MORIISHI,Yukihiro Nishiyama,Shinji Shimada

Journal of Investigative Dermatology   133 ( 9 )   2170 - 2179   2013.9

Cross-talk between the circadian clock circuitry and the immune system.[Review] Reviewed Major achievement

Cermakian N,Lange T,Golombek D,Sarkar D,Atsuhito NAKAO,Shigenobu Shibata,Mazzoccoli G

Chronobiology International   30 ( 7 )   870 - 888   2013.8

TSLPとアレルギー Major achievement

中尾　篤人

臨床免疫・アレルギー科   60 ( 1 )   28 - 31   2013.7

食物アレルギーの理解と治療法の将来展望 Major achievement

中尾　篤人

最新医学   ( 68 )   1466 - 1473   2013.6

TSLPとアレルギー Major achievement

中尾　篤人

アレルギー   62 ( 5 )   555 - 559   2013.5

Endogenous TGF-β Activity Limits TSLP Expression in the Intervertebral Disc Tissue by Suppressing NF-κB Activation. Reviewed Major achievement

Yong Zhu,Tetsuroh OHBA,Takashi ANDO,Kohji FUJITA,Kensuke KOYAMA,Yuki NAKAMURA,Ryohei KATOH,Hirotaka HARO,Atsuhito NAKAO

Journal of orthopaedic research   31   1144 - 1149   2013.3

Grape seed extract from "Koshu" cultivar antagonizes dioxin-induced aryl hydrocarbon receptor activation. Reviewed

Sugiyama T, Kitamura M, Sugita K, Hisamoto M, Okuda T, Nakao A

AMERICAN JOURNAL OF ENOLOGY AND VITICULTURE   64 ( 1 )   146 - 151   2013.3( ISSN：0002-9254 )

Biological clock dysfunction exacerbates contact hypersensitivity in mice. Reviewed Major achievement

Takita E,Yokota S,Tahara Yu,Hirao A,Aoki N,Nakamura Yuki,Atsuhito NAKAO,Shibata Shigenobu

Br J Dermatol   168 ( 1 )   39 - 46   2013.1

体内時計とアレルギー Major achievement

中尾　篤人

治療   94 ( 11 )   1859 - 1864   2012.11

体内時計によるアレルギー反応の時間的制御 Major achievement

中尾　篤人

感染 炎症 免疫   42 ( 3 )   58 - 61   2012.10

Dietary Resveratrol Prevents the Development of Food Allergy in Mice. Reviewed Major achievement

Yui Okada,Kyoko Oh-oka,Yuki Nakamura,Kayoko Ishimaru,Shuji Matsuoka,Ko Okumura,Hideoki Ogawa,Hisamoto Masashi,Tohru Okuda,Atsuhito NAKAO

PLoS One   7 ( 9 )   e44338   2012.9

The circadian clocks regulate daily rhythms in allergic reaction. Major achievement

32 ( 434 )   32 - 36   2012.9

食物アレルギーとその動物モデル Major achievement

中尾　篤人

アレルギーの臨床   32 ( 433 )   48 - 52   2012.8

アレルギーと体内時計 Major achievement

中尾　篤人

FOOD STYLE21   ( 7 )   24 - 26   2012.7

肥満細胞によるアレルギー反応の体内時計遺伝子を介する日内変動調節 Major achievement

中尾　篤人

炎症と免疫   20 ( 4 )   3 - 7   2012.6

アレルギーと体内時計 Major achievement

中尾　篤人

臨床免疫・アレルギー科   57 ( 6 )   681 - 685   2012.6

Transforming growth factor-β(1) promotes nasal mucosal mast cell chemotaxis in murine experimental allergic rhinitis. Reviewed Major achievement

Ouyang Y,Atsuhito NAKAO,Han D,Zhang L

ORL J Otorhinolaryngol Relat Spec   74 ( 3 )   117 - 123   2012.3

Age-related Changes in MCP-1, MMP-3 and VEGF Expression in the Degeneration of Mouse Intervertebral Disc Reviewed Major achievement

Kohji FUJITA,Tetsuroh OHBA,Takashi ANDO,Masanori WAKOU,Atsuhito NAKAO,Hirotaka HARO

Journal of Spine Research   3 ( 2 )   123 - 129   2012.2

Severe dermatitis with loss of epidermal Langerhans cells in human and mouse zinc deficiency. Reviewed Major achievement

KAWAMURA T,OGAWA Y,NAKAMURA Y,NAKAMIZO S,IZUMI A,NAKANO H,KABASHIMA K,KATAYAMA I,Schuichi KOIZUMI,KODAMA T,Atsuhito NAKAO,Shinji Shimada

J. Clin. Invest.   122 ( 2 )   722 - 732   2012.2

Maternal psychosocial factors determining the concentrations of transforming growth factor-beta in breast milk. Reviewed

Kondo N1, Suda Y, Nakao A, Oh-Oka K, Suzuki K, Ishimaru K, Sato M, Tanaka T, Nagai A, Yamagata Z

　   22 ( 8 )   853 - 861   2011.12

Pyridone 6, a Pan-JAK Inhibitor, Ameliorates Allergic Skin Inflammation of NC/Nga Mice via Suppression of Th2 and Enhancement of Th17. Reviewed Major achievement

Ryusuke NAKAGAWA,Yoshida H,Asakawa M,Tamiya T,Inoue N,Morita R,Inoue H,Atsuhito NAKAO,Yoshimura A

J IMMUNOL   187 ( 9 )   4611 - 4620   2011.11

体内時計は,アレルギー反応を制御するカギの1つである Major achievement

中尾　篤人

化学と生物   49 ( 11 )   740 - 742   2011.11

Decreased expression of EBI3 and Foxp3 in CD4+CD25+ regulatory T cells in murine experimental allergic rhinitis. Reviewed Major achievement

Ouyang Y,Atsuhito NAKAO,Fan E,Li Y,Zhao L,Zhang W,Han D,Zhang L

ORL Otorhinolaryngol Relat Spec   73 ( 6 )   313 - 320   2011.10

Lactobacillus bulgaricus OLL1181 activates the aryl hydrocarbon receptor pathway and inhibits colitis. Reviewed Major achievement

Takeyuki TAKAMURA,Daisuke HARAMA,Suguru FUKUMOTO,Yuki NAKAMURA,Naomi SHIMOKAWA,Kayoko ISHIMARU,Shuji IKEGAMI,Seiya MAKINO,Masanori KITAMURA,Atsuhito NAKAO

Immunol Cell Biol   89 ( 7 )   817 - 822   2011.10

Aryl hydrocarbon receptor経路の活性化によるデキストラン硫酸ナトリウム誘導性大腸炎の抑制 Major achievement

高村　武之,原間　大輔,下川　直美,中村　勇規,北村　正敬,中尾　篤人

消化器と免疫   ( 47 )   76 - 79   2011.6

アレルギー疾患と母乳中のTGF-β Major achievement

中尾　篤人

化学と生物   49 ( 6 )   392 - 397   2011.6

乳幼児アレルギー疾患の発症抑制と母乳中TGF-β Major achievement

中尾　篤人

日本小児アレルギー学会誌   25 ( 1 )   69 - 74   2011.6

Age-Related Expression of MCP-1 and MMP-3 in Mouse Intervertebral Disc in Relation to TWEAK and TNF-a Stimulation Reviewed Major achievement

Kohji FUJITA,Takashi ANDO,Tetsuroh OHBA,Masanori WAKOU,Nobutaka SATOH,Yuki NAKAMURA,Yuko Ohnuma,Yasushi HARA,Ryohei KATOH,Atsuhito NAKAO,Hirotaka HARO

JOURNAL OF ORTHOPAEDIC RESEARCH   30 ( 4 )   599 - 605   2011.4

Circadian clock gene Period2 regulates a time-of-day-dependent variation in cutanenous anaphylactic reaction. Reviewed Major achievement

Yuki NAKAMURA,Daisuke HARAMA,Naomi SHIMOKAWA,Mutsuko HARA,Ryuyo SUZUKI,Yu TAHARA,Kayoko ISHIMARU,Ryohei KATOH,Ko OKUMURA,Hideoki OGAWA,Shigenobu SHIBATA,Atsuhito NAKAO

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY   127 ( 4 )   1038 - 1045   2011.4

CD70 Is Selectively Expressed on Th1 but Not on Th2 Cells and Is Required for Th1-Type Immune Responses Reviewed Major achievement

Tatsuyoshi Kawamura,Youichi Ogawa,Shimozato Osamu,Takashi ANDO,Atsuhito NAKAO,Tetsuji Kobata,Ko Okamura,Hideo Yagita,Shinji Shimada

Journal of Investigative Dermatology   131 ( 6 )   1252 - 1261   2011.4

Induction of ΔNp63 by the newly identified keratinocyte-specific TGF-β signaling pathway with Smad2 and IKKα in squamous cell carcinoma. Reviewed

Fukunishi N1, Katoh I, Tomimori Y, Tsukinoki K, Hata R, Nakao A, Ikawa Y, Kurata S.

Neoplasia   12 ( 12 )   969 - 979   2010.12

アレルギー疾患と母乳中TGF-β Major achievement

中尾　篤人

医学のあゆみ   234 ( 10 )   983 - 986   2010.9

TGF-β signaling may play a role in the development of goblet cell hyperplasia in a mouse model of allergic rhinitis. Reviewed Major achievement

Yuhui Ouyang,Masanori MIYATA,Kyousuke HATSUSHIKA,Yuko Ohnuma,Ryohei KATOH,Hideoki OGAWA,Ko OKUMURA,Keisuke MASUYAMA,Atsuhito NAKAO

Allergology International   59 ( 3 )   313 - 319   2010.9

Activation of the aryl hydrocarbon receptor pathway may ameliorate dextran sodium sulfate-induced colitis in mice. Reviewed Major achievement

Takeyuki TAKAMURA,Daisuke HARAMA,Shuji MATSIOKA,Naomi SHIMOKAWA,Yuki NAKAMURA,Ko OKUMURA,Hideoki OGAWA,Masanori KITAMURA,Atsuhito NAKAO

IMMUNOLOGY AND CELL BIOLOGY   88 ( 6 )   685 - 689   2010.8

TGF-βシグナルと免疫系の恒常性 Major achievement

中尾　篤人

実験医学 増刊   28 ( 12 )   115 - 119   2010.8

Suppressive effects of transcription factor GATA-1 on cell type-specific gene expression in dendritic cells. Reviewed Major achievement

Naomi SHIMOKAWA,Chiharu NISHIYAMA,Nobuhiro NAKANO,Keiko MAEDA,Ryuyo SUZUKI,Mutsuko HARA,Tatsuo FUKAI,Tomoko TOKURA,Hiroaki MIYAJIMA,Atsuhito NAKAO,Hideoki OGAWA,Ko OKUMURA

Immunogenetics   62 ( 7 )   421 - 429   2010.7

The role and potential use of oral transsforming growth factor-β in the prevention of infant allergy Reviewed Major achievement

Atsuhito NAKAO

Clin Exp Allergy   40   725 - 730   2010.4

食物アレルギーの発症メカニズム Major achievement

中尾　篤人

実験医学 増刊   27 ( 20 )   195 - 199   2009.12

Thymic stromal lymphopoietin is a critical mediator of IL-13-driven allergic inflammation. Reviewed Major achievement

Masanori MIYATA,Yuki NAKAMURA,Naomi SHIMOKAWA,Yuko Ohnuma,Ryohei KATOH,S Matsuoka,Ko OKUMURA,Hideoki OGAWA,Keisuke MASUYAMA,Atsuhito NAKAO

Eur J Immunol   39 ( 11 )   3078 - 3083   2009.11

A subcytotoxic dose of subtilase cytotoxin prevents lipopolysaccharide-induced inflammatory responses, depending on its capacity to induce the unfolded protein response. Reviewed Major achievement

Daisuke Harama,Kensuke KOYAMA,Mai Mukai,Naomi SHIMOKAWA,Masanori MIYATA,Yuki Nakamura,Yuko Ohnuma,Hideoki OGAWA,Shuji Matsuoka,Adrienne W. Paton,James C. Paton,Masanori KITAMURA and Atsuhito NAKAO

J IMMUNOL   183 ( 2 )   1368 - 1374   2009.7

The latent form of transforming growth factor-β administered orally is activated by gastric acid in mice. Reviewed Major achievement

Yuki Nakamura,Masanori MIYATA,Takashi ANDOH,Naomi SHIMOKAWA,Yuko Ohnuma,Ryohei KATOH,Hideoki OGAWA,Ko OKUMURA,Atsuhito NAKAO

J NUTR   139 ( 8 )   1463 - 1468   2009.6

House dust mite allergen Der f 1 can induce the activation of latent TGF-beta via its protease activity. Reviewed Major achievement

Yuki Nakamura,Masanori MIYATA,Naomi SHIMOKAWA,Yuko Ohnuma,Ryohei KATOH,Hideoki OGAWA,Ko OKUMURA,Atsuhito NAKAO

FEBS LETT   583 ( 12 )   2088 - 2092   2009.6

TNF-α-Induced NF-κB Signaling Reverses Age-Related Declines in VEGF Induction and Angiogenic Activity in Intervertebral Disc Tissues Reviewed Major achievement

Tetsuroh OHBA,Hirotaka HARO,Takashi ANDO,Masanori WAKOU,Fumiko SUENAGA,Yoshinori ASO,Kensuke KOYAMA,Yoshiki HAMADA,Atsuhito NAKAO

Journal of Orthopaedic Research February 2009   27   229 - 235   2009.2

Transforming growth factor-β activity in commercially available pasteurized cow milk provides protection against inflammation in mice. Reviewed Major achievement

Tetsuro OZAWA,Masanori MIYATA,Mika NISHIMURA,Takashi ANDOH,Yuhui Ouyang,Tetsuroh OHBA,Naomi SHIMOKAWA,Yuko Ohnuma,Ryohei KATOH,Hideoki OGAWA,Atsuhito NAKAO

J NUTR   139 ( 1 )   69 - 75   2009.1

TSLPとアレルギー Major achievement

中尾　篤人

臨床免疫・アレルギー科   50 ( 6 )   692 - 696   2008.12

Cigarette smoke extract induces thymic stromal lymphopoietin expression, leading to TH2-type immune responses and airway inflammation. Reviewed Major achievement

Yuki NAKAMURA,Masanori MIYATA,Tetsuroh OHBA,Takashi ANDO,Kyousuke HATSUSHIKA,Fumiko SUENAGA,Naomi SHIMOKAWA,Yuko Ohnuma,Ryohei KATOH,Hideoki OGAWA,Atsuhito NAKAO

J ALLERGY CLIN IMMUN   122 ( 6 )   1208 - 1214   2008.12

TGF-βの経口摂取による食物アレルギー予防についての基礎的検討 Major achievement

中尾　篤人

アレルギア   37   69 - 71   2008.11

Mechanism of Signal Transduction in Tumor Necrosis Factor-Like Weak Inducer of Apoptosis-Induced Matrix Degradation by MMP-3 Upregulation in Disc Tissues Reviewed Major achievement

Masanori WAKO,Tetsuroh OHBA,Takashi ANDO,Yoshiyasu ARAI,Kensuke KOYAMA,Yoshiki HAMADA,Atsuhito NAKAO,Hirotaka HARO

SPINE   33 ( 23 )   2489 - 2494   2008.11

A Potential Role of Thymic Stromal Lymphopoietin in the Recruitment of Macrophages to Mouse Intervertebral Disc Cells via Monocyte Chemotactic Protein 1 Induction Reviewed Major achievement

Tetsuroh OHBA,Hirotaka HARO,Takashi ANDO,Kensuke KOYAMA,Kyousuke HATSUSHIKA,Fumiko SUENAGA,Yuko Ohnuma,Yuki NAKAMURA,Ryohei KATOH,Hideoki OGAWA,Yoshiki HAMADA,Atsuhito NAKAO

ARTHRITIS&RHEUMATISM   58 ( 11 )   3510 - 3519   2008.11

Ex vivo transfer of Smad7 decreases damage to the corneal endothelium after penetrating keratoplasty. Reviewed Major achievement

Funaki Toshinari,Ebihara Nobuyuki,Murakami Akira,Atsuhito NAKAO

JPN J OPHTHALMOL   52   204 - 210   2008.7

Mast cell regulation of epithelial TSLP expression plays an important role in the development of allergic rhinitis Reviewed Major achievement

Masanori MIYATA,Kyousuke HATSUSHIKA,Takashi ANDOH,Naomi SHIMOKAWA,Yuko Ohnuma,Ryohei KATOH,Hajime SUTO,Hideoki OGAWA,Keisuke MASUYAMA,Atsuhito NAKAO

Eur J Immunol   38 ( 6 )   1487 - 1492   2008.6

T cell receptor-mediated signaling induces GRP78 expression in T cells: The implications in maintaining T cell viability. Reviewed Major achievement

Shinichi TAKANO,Takashi ANDOH,Nobuhiko HIRAMATSU,Kanayama A,Shinya MAEKAWA,Yuko Ohnuma,Nobuyuki ENOMOTO,Hideoki Ogawa,Paton AW,Paton JC,Masanori KITAMURA,Atsuhito NAKAO

Biochemical and biophysical research communications   371 ( 4 )   762 - 766   2008.5

A possible link between resveratrol and TGF-beta: Resveratrol induction of TGF-beta expression and signaling. Reviewed Major achievement

Fumiko Suenaga,Kyousuke HATSUSHIKA,Shinichi TAKANO,Takashi ANDOH,Yuko Ohnuma,Hideoki Ogawa,Atsuhito NAKAO

FEBS LETT   582 ( 5 )   586 - 590   2008.1

Thymic stromal lymphopoietin secretion of synovial fibroblasts is positively and negatively regulated by Toll-like receptors/nuclear factor-κB pathway and interferon-γ/dexamethasone. Reviewed Major achievement

Tetsuro OZAWA,Kensuke KOYAMA,Takashi ANDO,Yuko Ohnuma,Kyousuke HATSUSHIKA,Tetsuroh OHBA,Hajime SUGIYAMA,Yoshiki HAMADA,Hideoki OGAWA,Ko OKUYAMA,Atsuhito NAKAO

Modern Rheumatology   17 ( 6 )   459 - 463   2007.12

Novel Function of TWEAK in Inducing Intervertebral Disc Degeneration Reviewed Major achievement

Masanori WAKO,Hirotaka HARO,Takashi ANDO,Kyousuke HATSUSHIKA,Tetsuroh OHBA,Sadahiro IWABUCHI,Atsuhito NAKAO,Yoshiki HAMADA

Journal of Orthopaedic Research   25   1438 - 1446   2007.11

Orally administered TGF-β is biologically active in the intestinal mucosa and enhances oral tolerance. Reviewed Major achievement

Takashi ANDO,Kyousuke HATSUSHIKA,Masanori WAKO,Tetsuroh OHBA,Kensuke KOYAMA,Yuko Ohnuma,Ryohei KATOH,Hideoki OGAWA,Ko OKUMURA,Luo J,Wyss-Coray T,Atsuhito NAKAO

J ALLERGY CLIN IMMUN   120 ( 4 )   916 - 923   2007.10

Transforming Growth Factor-β2 polymorphisms are associated with childhood atopic asthma. Reviewed Major achievement

Hatsushika K,Hirota T,Harada M,Sakashita M,Kanzaki M,Takano S,Doi S,Fujita K,Enomoto T,Ebisawa M,Yoshihara S,Sagara H,Fukuda T,Masuyama,Katoh R,Matsumoto K,Saito H,Ogawa H,Tamari M,Atsuhito NAKAO

Clin Exp Allergy   37 ( 8 )   1165 - 1174   2007.8

Imatinib mesylate both prevents and treats the arthritis induced by type II collagen antibody in mice. Reviewed Major achievement

Koyama K,Hatsushika K,Ando T,Sakuma M,Wako M,Kato R,Sugiyama H,Hamada Y,Ogawa H,Nakao A

MODERN RHEUMATOLOGY   17 ( 4 )   306 - 310   2007.8

TGF-βシグナルと免疫アレルギー Major achievement

中尾　篤人

細胞   39 ( 8 )   22 - 25   2007.7

TGF-β/Smad Major achievement

中尾　篤人

炎症と免疫   15 ( 4 )   117 - 119   2007.7

A possible role for TSLP in inflammatory arthritis Reviewed Major achievement

Kensuke KOYAMA,Tetsuro OZAWA,Kyousuke HATSUSHIKA,Takashi ANDO,Shinichi TAKANO,Masanori WAKOU,Fumiko SUENAGA,Yuko Ohnuma,Tetsuroh OHBA,Ryohei KATOH,Hajime SUGIYAMA,Yoshiki HAMADA,Hideoki OGAWA,Ko OKUMURA,Atsuhito NAKAO

Biochemical and Biophysical Research Communications   357 ( 1 )   99 - 104   2007.5

Human Eosinophils Have an Intact Signaling Pathway Leading to a Major Transforming Growth Factor-β Target Gene Expression Reviewed Major achievement

Mirei Kanzaki,Naotaka Shibagaki,Kyouske Hatsushika,Hiroshi Mitsui,Takashi Inozume,Atsuhi Okamoto,Yoh DOBASHI,Hideoki Ogawa,Shinji Shimada,Atsuhito NAKAO

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY   142 ( 4 )   309 - 317   2007.4

FK506 inhibits the enhancing effects of TGF-β on would healing in a rabbit dermal ulcer model. Reviewed Major achievement

T Hasegawa,K Sumiyoshi,H Tsuchihashi,S Ikeda,Atsuhito NAKAO,H Ogawa

J DERMATOL SCI   47 ( 1 )   37 - 40   2007.4

Smad4 is essential for down-regulation of E-cadherin induced by TGF-β in pancreatic cancer cell line PANC-1. Reviewed Major achievement

Takano S,Kanai F,Jazag A,Ijichi H,Yao J,Ogawa H,Enomoto N,Omata M,Nakao A

JOURNAL OF BIOCHEMISTRY   141 ( 3 )   345 - 351   2007.3

TWEAK inhibits TGF-beta-induced contraction of normal and keloid fibroblast-embedded collagen gel. Reviewed Major achievement

Hitoshi Tsuchihashi,Toshio Hasegawa,Koji Sumiyoshi,Shigaku Ikeda,Takashi ANDOH,Atsuhito NAKAO,Ko Okumura,Hideoki Ogawa

J DERMATOL SCI   45 ( 3 )   216 - 218   2007.3

TGF-β type Ⅰreceptor kinase inhibitor down-regulates rheumatoid synovicytes and prevents the type Ⅱ collagen antibody Reviewed Major achievement

Michitomo SAKUMA,Kyousuke HATSUSHIKA,Kensuke KOYAMA,Ryohei KATOH,Takashi ANDO,Yoshiyuki WATANABE,Masanori WAKOU,Mirei Kanzaki,Shinichi TAKANO,Hajime SUGIYAMA,Yoshiki HAMADA,Hideoki OGAWA,Ko OKUMURA,Atsuhito NAKAO

International immunology   19 ( 2 )   117 - 126   2007.2

TGF-betaスーパーファミリーによるシグナル伝達機構と疾患 Major achievement

中尾　篤人

医学遺伝子MOOK(6)シグナル伝達病を知る   6   80 - 85   2006.12

TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells. Reviewed Major achievement

Takashi ANDO,Jiro ICHIKAWA,Masanori　WAKO,Kyosuke HATSUSHIKA,Yoshiyuki WATANABE,Michitomo SAKUMA,Kachio TASAKA,Hideoki OGAWA,Yoshiki HAMADA,Hideo YAGITA,Atsuhito NAKAO

ARTHRITIS RES THER   8 ( 5 )   R146 - 155   2006.9

Participation of an abnormality in the transforming growth factor-β signaling pathway in resistance of malignant glioma cells to growth inhibition induced by that factor Reviewed Major achievement

JOURNAL OF NEUROSURGERY   105   119 - 128   2006.7

Effects of arachidonic acid analogs on FcepsilonRI-mediated activation of mast cells. Reviewed Major achievement

BIOCHEM BIOPHYS ACTA   1738   19 - 28   2005.12

CDK5 regulates cell-cell and cell-matarix adhesion in human keratinocytes. Reviewed Major achievement

THE BRITISH JOURNAL OF DERMATOLOGY   153 ( 1 )   37 - 45   2005.7

Gemcitabine inhibits viability, growth, and metastasis of osteosarcoma cell lines Reviewed Major achievement

JOURNAL OF ORTHOPAEDIC RESEARCH   23 ( 4 )   964 - 969   2005.7

SB-431542 inhibits TGF-beta-induced contraction of collagen gel by normal and keloid fibroblasts. Reviewed Major achievement

JOURNAL OF DERMATOLOGICAL SCIENCE   39 ( 1 )   33 - 38   2005.7

Trastuzumab-mediated antibody-dependent cellular cytotoxicity against esophageal squamous cell carcinoma Reviewed Major achievement

Clinical Cancer Research   11 ( 13 )   4898 - 4904   2005.7

Smad3 deficiency in mast cells provides efficient host protection against acute septic peritonitis. Reviewed Major achievement

JOURNAL OF IMMUNOLOGY   174 ( 7 )   4193 - 4197   2005.4

Suppression of serum IgE response and sysemic anaphylaxis in a food allergy model by orally administered high-dose TGF-β Reviewed Major achievement

International Immunology   17 ( 6 )   705 - 712   2005.4

Smad7と自己免疫/炎症性疾患 Major achievement

中尾　篤人

分子リウマチ   2   22 - 27   2005.3

Activation of the Smad pathway in glomeruli from a spontaneously diabetic rat model, OLETF rats Reviewed Major achievement

Furuse Y,Hashimoto N,Maekawa M,Yoyama Y,Atsuhito NAKAO,Iwamoto I,Sakurai K,Suzuki Y,Yagui K,Yuasa S,Toshimori K,Saito Y

NEPHRON EXP NEPHROL   98   100 - 108   2004.12

TGF-betaのシグナル伝達の制御機構と疾患 Major achievement

中尾　篤人

山梨医科学雑誌   19   79 - 82   2004.12

MD-2 is required for the full responsiveness of mast cells to LPS but not to PGN. Reviewed Major achievement

Ushio H,Atsuhito NAKAO,Supajatura V,Miyake K,Okumura K,Ogawa H

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   323 ( 2 )   491 - 498   2004.10

Smad3 deficiency attenuates renal fibrosis, inflammation, and apoptosis after unilateral ureteral obstruction. Reviewed Major achievement

Inazaki K,Kanamaru Y,Kojima Y,Sueyoshi N,Ko Okumura,Yamashiro Y,Hideoki Ogawa,Atsuhito NAKAO

KIDNEY INTERNATIONAL   66 ( 2 )   597 - 604   2004.8

Exogenous Smad3 accelerates wound healing in a rabbit dermalulcer model Reviewed Major achievement

Sumiyoshi K,Atsuhito NAKAO,Setoguchi Y,Ko Okumura,Hideoki Ogawa

JOURNAL OF INVESTIGATIVE DERMATOLOGY   123 ( 1 )   229 - 236   2004.7

Induction of RANTES by TWEAK/Fn14 interaction in human keratinocytes Reviewed Major achievement

Jin L,Atsuhito NAKAO,Nakayama M,Yamaguchi N,Kojima Y,Nakano N,Tsuboi R,Ko Okumura,Hideo Yagita,Hideoki Ogawa

JOURNAL OF INVESTIGATIVE DERMATOLOGY   122 ( 5 )   1175 - 1179   2004.5

TWEAK/Fn14 interaction stimulates human bronchial epithelial cells to produce IL-8 and GM-CSF. Reviewed Major achievement

Xu H,Atsushi OKAMOTO,Jiro Ichikawa,Takashi ANDOH,Kachio TASAKA,Keisuke MASUYAMA,Hideoki Ogawa,Hideo Yagita,Ko Okumura,Atsuhito NAKAO

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   318 ( 2 )   422 - 427   2004.5

Dual role of Fcgamma receptor in transient focal cerebral ischemia in mice. Reviewed Major achievement

Komine-Kobayashi M,Chou N,Mochizuki H,Atsuhito NAKAO,Mizuno Y,Urabe T

STROKE   35 ( 4 )   958 - 963   2004.4

Expression of phosphorylated Smad2 in normal human epidermis Reviewed Major achievement

Prapars M,Atsuhito NAKAO,Nakano H,Jin L,Ogawa H

JOURNAL OF DERMATOLOGICAL SCIENCE   34 ( 1 )   54 - 55   2004.2

TGF-beta/Smad分子を標的とした肺疾患の治療 Major achievement

中尾　篤人

週刊医学のあゆみ   208 ( 5 )   408 - 411   2004.1

TGF-betaのシグナル伝達異常と発癌 Major achievement

中尾　篤人

バイオセラピー   17   522 - 527   2003.11

Up-regulation of interleukin-13 receptor a1 on human keratinocytes in the skin of psoriasis and atopic dermatitis. Reviewed Major achievement

Wongpiyabovorn J,Suto H,Ushio H,Izuhara K,Mitsuishi K,Ikeda S,Atsuhito NAKAO,Okumura K,Ogawa H

JOURNAL OF DERMATOLOGICAL SCIENCE   33 ( 1 )   31 - 40   2003.10

Interferon-gamma interferes with transforming growth factor-beta signaling through direct interaction of YB-1 with Smad3. YB-1 with Smad3 Reviewed Major achievement

Higashi K,Inagaki Y,Fujimori K,Atsuhito NAKAO,Kaneko H,Nakatsuka I

JOURNAL OF BIOLOGICAL CHEMISTRY   278 ( 44 )   43470 - 43479   2003.10

Interferon-alpha down-regulates collagen gene transcription and suppresses experimental hepatic fibrosis in mice Reviewed Major achievement

Inagaki Y,Nemoto T,Kushida M,Sheng Y,Higashi K,Ikeda K,Kawada N,Shirasaki F,Takehara K,Sugiyama K,Fujii M,Yamauchi H,Atsuhito NAKAO

HEPATOLOGY   38 ( 4 )   890 - 899   2003.10

Smads regulate collagen gel contraction by human dermal fibroblasts Reviewed Major achievement

Sumiyoshi K,Atsuhito NAKAO,Setoguchi Y,Okumura K,Tsuboi R,Ogawa H

BRITISH JOURNAL OF DERMATOLOGY   149 ( 3 )   464 - 470   2003.9

Involvement of p300 in TGF-beta/Smad-pathway-mediated alpha2(I) collagen expression in mouse mesangial cells. Reviewed Major achievement

Kanamaru Y,Atsuhito NAKAO,Tanaka Y,Inagaki Y,Ushio H,Shirato I,Horikoshi S,Okumura K,Ogawa H,Tomino Y

NEPHRON EXP NEPHROL   95 ( 1 )   e36 - 42   2003.8

Transforming Growth Factor-beta (TGF-beta)のシグナル伝達機構 Major achievement

中尾　篤人

分子細胞治療   2   409 - 411   2003.8

IFN-gamma fails to antagonize fibrotic effect of TGF-beta on keloid-derived dermal fibroblasts. Reviewed Major achievement

Hasegawa T,Atsuhito NAKAO,Sumiyoshi K,Tsuboi R,Ogawa H

JOURNAL OF DERMATOLOGICAL SCIENCE   32 ( 1 )   19 - 24   2003.6

p38 mitogen-activated protein kinase is involved in activin A- and HGF-mediated expression of pro-endocrine gene neurogenin3 in AR42J-B13 cells. Reviewed Major achievement

Ogihara T,Watada H,Kanno R,Ikeda F,Nomiyama T,Tanaka Y,Atsuhito NAKAO,German MS,Kojima I,Kawamori R

JOURNAL OF BIOLOGICAL CHEMISTRY   278 ( 24 )   21693 - 21700   2003.6

TRAIL expression in atopic dermatitis. Reviewed Major achievement

Warnnissorn P,Atsuhito NAKAO,Suto H,Ushio H,Yamaguchi N,Yagita H,Okumura K,Ogawa H

BRITISH JOURNAL OF DERMATOLOGY   148 ( 4 )   829 - 831   2003.4

Smad7 suppresses the inhibitory effect of TGF-beta2 on corneal endothelial cell proliferation and accelerates corneal endothelial wound closure in vitro. Reviewed Major achievement

Funaki T,Atsuhito NAKAO,Ebihara N,Setoguchi Y,Fukuchi Y,Okumura K,Ra C,Ogawa H,Kanai A

CORNEA   22 ( 2 )   153 - 9   2003.3

Transforming growth factor-beta (TGF-beta)とSmad Major achievement

中尾　篤人

臨床検査   47   303 - 309   2003.3

TGF-beta/Smad signaling inhibits IFN-gamma and TNF-alpha-induced TARC (CCL17) production in HaCaT cells. Reviewed Major achievement

Sumiyoshi K,Atsuhito NAKAO,Setoguchi Y,Tsuboi R,Okumura K,Ogawa H

JOURNAL OF DERMATOLOGICAL SCIENCE   31 ( 1 )   53 - 8   2003.2

Expression of Smad7 in bronchial epithelial cells is inversely correlated to basement membrane thickness and airway hyperresponsiveness in patients with asthma. Reviewed Major achievement

Atsuhito NAKAO, Sagara H, Setoguchi Y, Okada T, Okumura K, Ogawa H, Fukuda T

J ALLERGY CLIN IMMUNOL   110 ( 6 )   873 - 878   2002.12

Role of transforming growth factor-beta/Smad signaling pathway in enhanced production of glomerular extracellular matrix in IgA nephropathy of high-serum IgA ddY mice. Reviewed Major achievement

Kanamaru Y, ,Atsuhito NAKAO, ,Ra C, ,Okumura K, ,Muso E, ,Ogawa H, ,Kobayashi I, ,Horikoshi S, ,Tomino Y

NEPHROLOGY   7   S151 - S155   2002.10

Transcriptional regulation of type I collagen gene expression by transforming growth factor-beta/Smad signaling and its antagonistic factors. Reviewed Major achievement

Inagaki Y,Nemoto T,NAKAO ATSUHITO

Connective Tissue   34   139 - 146   2002.10

Smad7 mediates transforming growth factor-beta-induced apoptosis in mesangial cells. Reviewed Major achievement

Okado T, Terada Y, Tanaka H, Inoshita S, Atsuhito NAKAO ,Sasaki S

KIDNEY INT   62 ( 4 )   1178 - 1186   2002.10

a new key player in TGF-beta-associated disease. Reviewed Major achievement

Atsuhito NAKAO, Okumura K, Ogawa H

TRENDS MOL MED   8 ( 8 )   361 - 363   2002.8

Activation of TGF-beta/Smad2 signaling is associated with airway remodeling in asthma. Reviewed Major achievement

Sagara H, ,Okada T, ,Okumura K, ,Ogawa H, ,Ra C, ,Fukuda T, ,Atsuhito NAKAO

J ALLERGY CLIN IMMUNOL   110 ( 2 )   249 - 254   2002.8

Chronic graft-versus-host autoimmune disease in Fc receptor gamma chain-deficient mice results in lipoprotein glomerulopathy. Reviewed Major achievement

Kanamaru Y, ,Atsuhito NAKAO, ,Shirato I, ,Okumura K, ,Ogawa H, ,Tomino Y, ,Ra C

J AM SOC NEPHROL   13 ( 6 )   1527 - 1533   2002.6

Toll-like receptor 2 and 4 of mast cells have different functional responses in allergy and innate immunity. Reviewed Major achievement

Supajatura V, ,Ushio H, ,Atsuhito NAKAO, ,Akira S, ,Okumura K, ,Ra C, ,Ogawa H

J CLIN INVEST   109 ( 10 )   1351 - 1359   2002.5

Localization of intestinal intraepithelial T lymphocytes involves regulation of alphaEbeta7 expression by TGF-beta. Reviewed Major achievement

Suzuki R, ,Atsuhito NAKAO ,Kanamaru Y, ,Okumura K, ,Ogawa H, ,Ra C

INT IMMUNOL   14 ( 4 )   339 - 345   2002.4

SMAD/TGF-betaシグナル。 Major achievement

中尾篤人

免疫疾患Ver.2（別冊医学のあゆみ）   96 - 100   2002.3

TGF-beta1 suppresses atopic dermatitis-like skin lesions in NC/Nga mice. Reviewed Major achievement

Sumiyoshi K, ,Atsuhito NAKAO, ,Ushio H, ,Mitsuishi K, ,Okumura K, ,Tsuboi R, ,Ra C, ,Ogawa H

CLIN EXP ALLERGY   32 ( 2 )   309 - 314   2002.2

Gene transfer of Smad7 using electroporation of adenovirus prevents renal fibrosis in post-obstructed kidney. Reviewed Major achievement

Terada Y, ,Hanada S, ,Atsuhito NAKAO, ,Kuwahara M, ,Sasaki S, ,Marumo F

KIDNEY INT   61 ( sym1 )   S94 - S98   2002.1

TGF-betaシグナルの多様性、多面性。 Major achievement

中尾篤人

感染炎症免疫   31   276 - 285   2001.12

Identification of NASH1, a novel protein containing a nuclear localization signal, a sterile alpha motif, and an SH3 domain preferentially expressed in mast cells. Reviewed Major achievement

Uchida T, ,Atsuhito NAKAO, ,Nakano N, ,Kuramasu A, ,Saito H, ,Okumura K, ,Ra C, ,Ogawa H

BIOCHEM BIOPHYS RES COMMUN   288 ( 1 )   137 - 141   2001.10

Cutaneous findings in HIV-1-positive patients in Thailand. Reviewed Major achievement

Palungwachira P, ,Chirachanakul P, ,Palungwachira P, ,Chalugun P, ,Atsuhito NAKAO, ,Takamori K, ,Ogawa H

THE JOURNAL OF DERMATOLOGY   28 ( 10 )   584 - 585   2001.10

Protective roles of mast cells against enterobacterial infection are mediated by Toll-like receptor 4. Reviewed Major achievement

Supajatura S, ,Ushio H, ,Atsuhito NAKAO, ,Okumura K, ,Ra C, ,Ogawa H

J IMMUNOL   167 ( 4 )   2250 - 2256   2001.8

Impairment of bleomycin-induced lung fibrosis in CD28-deficient mice. Reviewed Major achievement

Okazaki T, ,Atsuhito NAKAO, ,Nakano H, ,Takeda K, ,Shimozato O, ,Takahashi F, ,Takahashi K, ,Yagita H, ,Okumura K

J IMMUNOL   167 ( 4 )   1977 - 1981   2001.8

The TGF-beta1 paradox in asthma. Reviewed Major achievement

Atsuhito NAKAO

TRENDS IMMUNOL   22 ( 6 )   300 - 301   2001.6

Is transforming growth factor-beta1 the key to suppression of human asthma? Reviewed Major achievement

Atsuhito NAKAO

TRENDS IMMUNOL   22 ( 3 )   115 - 118   2001.3

Blockade of TGF-beta signaling in T cells prevents the development of experimental glomerulonephritis. Reviewed Major achievement

Kanamaru Y, ,Atsuhito NAKAO, ,Mamura M, ,Suzuki Y, ,Shirato I, ,Okumura K, ,Tomino Y, ,Ra C

J IMMUNOL   166 ( 4 )   2818 - 2823   2001.2

Constitutive phosphorylation and nuclear localization of Smad3 correlate to increased collagen gene transcription in activated hepatic stellate cells. Reviewed Major achievement

Inagaki Y,Mamura M,Kanamaru Y, ,Greenwell P, ,Takehara K, ,ten Dijke P, ,Atsuhito NAKAO

J CELL PHYSIOL   187 ( 1 )   117 - 123   2001.2

Interaction between GC box binding factors and Smad proteins modulates cell lineage-specific alpha2(I) collagen gene transcription. Reviewed Major achievement

Inagaki Y, ,Nemoto T, ,Atsuhito NAKAO, ,ten Dijke P, ,Kobayashi K, ,Takehara K, ,Greenwel P

J BIOL CHEM   276 ( 19 )   16573 - 16579   2001.2

Establishment and characterization of a murine mast cell line derived from NC/Nga mice. Reviewed Major achievement

Hira K, ,Mitsuishi K, ,Kawamoto K, ,Suto H, ,Atsuhito NAKAO, ,Ra C, ,Ogawa H

Int Arch Allergy Clin Immunol   125 ( S1 )   67 - 70   2001.1

Smad7によるTGF-βシグナルの制御と疾患

中尾篤人

Molecular Medicine   ( 38 )   304 - 308   2001.1

Smad7 as an anti-fibrotic agent.

中尾　篤人

胃と透析   ( 50 )   209 - 212   2001.1

膠原病・リウマチ・アレルギー研修ノート Major achievement

中尾　篤人（-）

診断と治療社  2016.4 

Inhibitory Smads: mechanisms of action and roles in human diseases Major achievement

Atsuhito NAKAO

Springer  2006.8 

Transcriptional activation of type I collagen gene during hepatic fibrogenesis. Major achievement

Inagaki Y,Nemoto T,Atsuhito NAKAO

2003.8 

基礎から学ぶ上皮サイトカインとそのメカニズム～TSLPを中心に～ Invited

中尾篤人

第72回アレルギー学会学術大会  2023.10 

マスト細胞を標的とした新規アレルギー疾患治療薬としての高選択的KIT阻害剤の開発

中尾篤人

第72回アレルギー学会学術大会  2023.10 

Organic cation transporter-3 regulates intracellular histamine levels and IgE-mediated histamine release in mast cell

2023.10 

Ethyl caffeate can antagonize the aryl hydrocarbon receptor signaling, which is associated with its anti-allergic property

2023.10 

時計遺伝子Bmal1による酸化ストレス応答を介したIgE誘導マスト細胞脱顆粒反応の制御 Invited

中村　勇規

日本睡眠学会第45回定期学術集会・第30回日本時間生物学会学術大会　合同大会  2023.9 

体内時計と喘息・アレルギー Invited

中尾篤人

第４回日本喘息学会総会学術大会  2023.7 

Cha o 3 may not be a major allergen in Japanese cypress pollinosis. International conference

Kobayashi Y

EAACI Hybrid Congress 2023  2023.6 

Identification of a highly selective small molecule KIT inhibitor that inhibits human mast cell survival and differentiation. International conference

Nakao A

EAACI Hybrid Congress 2023  2023.6 

基礎から学ぶ上皮サイトカインとそのメカニズム Invited

中尾篤人

第53回 日本職業・環境アレルギー学会総会・学術大会  2023.5 

MOD000001, a Novel Highly Selective and Orally Available KIT Inhibitor, Suppresses Passive Cutaneous Anaphylactic (PCA) Reaction and Food Allergy in Mice. International conference

Nakamura Y

2023 AAAAI Annual Meeting  2023.2 

喘息の多彩な炎症経路を紐解く―TSLPと重症喘息― Invited

中尾篤人

第5回日本アレルギー学会九州・沖縄支部地方会  2023.2 

スギ・ヒノキ花粉症患者の主要アレルゲンに対する好塩基球活性化試験の解析

小林義照

第8回日本アレルギー学会関東地方会  2022.12 

マスト細胞サブセットにおける概日時計の役割

中村勇規

第29回 日本時間生物学会学術大会  2022.12 

Circadian control of mast cell activation Invited

The 71st Annual Meeting of The Japanese Society of Allergology  2022.10 

Type2炎症経路における上皮サイトカインの重要性 Invited

第71回日本アレルギー学会学術大会  2022.10 

アレルギーと時間医学 Invited

第7回日本アレルギー学会関東地方会  2022.3 

アレルギー疾患の時間治療 Invited

第42回日本臨床薬理学会学術集会  2021.12 

糞線虫感染防御における概日時計の役割 Invited

中村　勇規

第6回日本アレルギー学会関東地方会  2021.11 

核内受容体REV-ERB特異的合成アゴニスト（SR9009）は概日時計非依存的にマスト細胞の活性化を阻害する Invited

石丸　かよ子

第6回日本アレルギー学会関東地方会  2021.11 

マスト細胞におけるEthyl-caffeateの脱顆粒反応抑制効果について Invited

石川　緋佳里（修士）

第6回日本アレルギー学会関東地方会  2021.11 

ウイルス感染症と概日時計 Invited

第28回日本時間生物学会学術大会  2021.11 

概日時計によるⅠ型アレルギー疾患の制御 Invited

中村　勇規

第28回日本時間生物学会学術大会  2021.11 

アレルギーの時間医学 Invited

第127回日本小児科学会甲信地方会  2021.11 

アレルギーとストレスをリンクするカギ Invited

第37回日本ストレス学会学術総会  2021.10 

時計じかけのアレルギー Invited

第70回日本アレルギー学会学術大会  2021.10 

糞線虫感染防御における概日時計の役割

中村　勇規

第70回日本アレルギー学会学術大会  2021.10 

白ワインポリフェノールによるマスト細胞脱顆粒反応の抑制

石川　緋佳里（修士）

第70回日本アレルギー学会学術大会  2021.10 

アレルギーと体内時計 Invited

第57回日本小児アレルギー学会学術大会  2020.10 

IgE依存性のアレルギー反応と時間の関係 Invited

第68回日本アレルギー学会学術大会  2019.6 

アレルギーと体内時計

第33回日本救命医療学会　総会・学術集会  2018.9 

アレルギーと概日時計

第23回日本病態プロテアーゼ学会学術集会  2018.8 

Regulation of steady state plasma histamine levels by the mast cell clock. International conference

Yuki Nakamura

2018 SRBR Meeting  2018.5 

The frequency of Th17 cells in The small intestine exhibits a day-night variation dependent on circadian clock activity. International conference

Ha Le

2018 SRBR Meeting  2018.5 

Circadian regulation of allergy.

Nakamura Y, Nakao A

The 95th Annulal Meeting of Physiological Society of Japan  2018.3 

Resveratrol inhibits IL-33-mediated mast cell activation.

Nakajima S, Nakao A

第46回日本免疫学会学術集会  2017.12 

Regulation of plasma histamine levels by the mast cell clock and its modulation by stress.

Nakamura Y, Nakao A

第46回日本免疫学会学術集会  2017.12 

マスト細胞の概日時計による血中ヒスタミン濃度の調節

中村勇規,柴田重信,中尾篤人

第40回日本分子生物学会年会  2017.12 

Regulation of plasma histamine levels by the mast cell clock.

Nakamura Y, Shibata S, Nakao A

第24回日本時間生物学会学術大会  2017.10 

アレルギーと体内時計

第56回日本鼻科学会総会・学術講演会  2017.9 

Circadian biology of psoriasis. Invited

2017.9 

マスト細胞の概日時計による血中ヒスタミン濃度の調節.

中村勇規,中尾篤人

第66回日本アレルギー学会学術大会  2017.6 

Circadian regulation of allergic reaction.

Nakao A

第66回日本アレルギー学会学術大会  2017.6 

Restraint stress induces nocturia in mice International conference Major achievement

32nd Annual EAU Congress(Europian Association of Urology 2017)  2017.3 

一般演題(学会賞候補演題)基礎 急性ストレスは末梢の時計遺伝子発現リズム異常と夜間頻尿・夜尿を引き起こす Major achievement

井原　達矢,三井　貴彦,中村　勇規,大竹　裕子,吉良　聡,澤田　智史,中込　宙史,中尾　篤人,武田　正之

第23回日本排尿機能学会  2016.12 

5-amino salicylic acid (5-ASA) induces the colonic regulatory Tcells via the activation of the aryl hydrocarbon receptor signaling pathway. Major achievement

第45回日本免疫学会学術集会  2016.12 

Migration of Th17 cells to the small intestine is temporally regulated by the circadian clock. Major achievement

第45回日本免疫学会学術集会  2016.12 

Inhibition of IgE-mediated allergic reaction by pharmacologically targeting the circadian clock. International conference Major achievement

Yuki NAKAMURA,Atsuhito NAKAO,Shigenobu SHIBATA

第45回日本免疫学会学術集会  2016.12 

Regulation of plasma histamine levels by the mast cell clock and its modulation by stress. Major achievement

第23回日本時間生物学会学術大会  2016.11 

Clock genes regulate circadian rhythm of VNUT and Connesin 26 expressions and ATP release after stretch stimulate in the cultured urothelial cells International conference Major achievement

2016 The 11th Pan-Pacific Continence Society (PPCS) Annual Meeting  2016.10 

Circadian Regulations of Piezo1, TRPV4, Connexin26, and VNUT by Clock Genes in the Mouse Bladder Urothelium International conference Major achievement

International Continence Society 46th Annual Meeting  2016.9 

AHR activation by probiotics inhibits colitis. International conference Major achievement

AHR 2016 The aryl hydrocarbon receptor as a central mediator of health and disease  2016.8 

薬理学的概日時計制御によるIgE依存性アレルギー反応の抑制 Major achievement

第65回日本アレルギー学会学術大会  2016.6 

Inhibition of CD23-mediated Serum IgE-facilitated allergen presentation by allergen-specific immunotherapy with japanese cedar pollinosis International conference

European Academy of Allergy and Clinical Immunology  2016.6 

Circadian Regulation of Allergic Reaction. International conference Major achievement

2016 SRBR Meeting  2016.5 

Clock Genes Regulate Circadian Rhythm of Vnut Expression, Connexin26 Expression and Stretch-Evoked ATP Release in the Cultured Urothelial Cells International conference Major achievement

The 112th Annual Meeting of the American Urological Association  2016.5 

Glock genes regulate sensation of bladder fullness in cultured urothelial cells Major achievement

The 104th Annual Meeting of the Japanese Urological Assosiation  2016.4 

花粉症体内時計で緩和

2016.4 

The mast cell-clock regulates blood histamine levels: implication for stress-induced exacerbation of allergy. International conference Major achievement

31th symposium of the Collegium Internationale Allergologicum  2016.4 

Clock genes regulate circadian rhythm of Piazo1 and TRPV4 expressions and intracellular Ca2+influx after strech simulation in the cultured urothelial cells Major achievement

31st Annual EAU Congress  2016.3 

Inhibition of IgE-Mediated Allergic Reaction By Pharmacologically Targeting the Circadian Clock. Major achievement

2016 AAAAI Annual Meeting  2016.3 

スギ花粉症モデルマウスを用いた舌下免疫療法(SLIT)クロノセラピーの検討 Major achievement

五十嵐　賢,鈴木　啓介,中村　勇規,石丸　かよ子,深野　千陽,増山　敬祐,土井　雅津代,中尾　篤人

第34回日本耳鼻咽喉科免疫アレルギー学会  2016.2 

悪性グリオーマと免疫療法:トリプトファン代謝酵素Indoleamine 2,3- dioxygenase(IDO)の抑制とテモゾロミドの併用効果 Major achievement

埴原　光人,川瀧　智之,大岡　杏子,中尾　篤人,木内　博之

山梨大学 国立精神・神経医療研究センター合同シンポジウム  2016.1 

Ciracadian Gene Clock Regulates Psoriasis-Like Skin Inflammation in Mice Major achievement

The 40th Annual Meeting of the Japanese Society for Investigative Dermatology  2015.12 

マウスイミキド乾癬モデルにおける体内時計の関与 Major achievement

安藤　典子,川村　龍吉,島田　眞路,中尾　篤人

第82回日本皮膚科学会山梨地方会  2015.12 

時計遺伝子clockミュータントマウスは夜間頻尿・夜間多尿を呈する Major achievement

井原　達矢,吉良　聡,宮本　達也,中込　宙史,澤田　智史,三井　貴彦,小林　英樹,芳山　充晴,武田　正之,中村　勇規,中尾　篤人,篠﨑　陽一,小泉　修一

第8回排尿障害モデル動物研究会  2015.12 

薬理学的概日時計制御によるIgE依存性アレルギー反応の制御. Major achievement

中村　勇規,中尾　篤人,柴田重信

第22回日本時間生物学会学術大会  2015.11 

Allergy:From Bench to Bedside and Beyond. Major achievement

The 44th Annual Meeting of the Japanease Society for Immunology  2015.11 

CLOCK MUTANT MOUSE IS A NOVEL EXPERIMENTAL MODEL FOR NOCTURIA/NOCTURNAL POLYURIA Major achievement

International Continence Society 2015  2015.10 

CLOCK MUTANT MOUSE IS A EXPERIMENTAL MODEL FOR NOCTURIA/NOCTURNAL POLYURIA Major achievement

Nagoya Shinshu Forum 2015  2015.9 

Synergistic anti-tumor effect with indoleamine 2,3-dioxygenase inhibition and temozolomide in a murine glioma model Major achievement

2015WFNS 15th Interim Meeting of the World Federation of Neurosurgical Societies  2015.9 

Synergistic anti-tumor effect with indoleamine 2,3-dioxygenase inhibition and temozolomide in a murine glioma model Major achievement

The 16th Annual Meeting of the Japan Society of Molecular Neurosurgery  2015.8 

スギ花粉症患者好塩基球のスギ花粉に対する反応性の日内変動 Major achievement

安藤　典子,中村　勇規,石丸　かよ子,島田　眞路,中尾　篤人

第64回日本アレルギー学会学術大会  2015.5 

IL-33依存性マスト細胞応答は時計遺伝子Clockにより制御される Major achievement

第64回日本アレルギー学会学術大会  2015.5 

レスベラトロール二量体であるε-ビニフェリンによるIgE依存性アレルギー反応の抑制効果 Major achievement

第64回日本アレルギー学会学術大会  2015.5 

SubAB Prevent Joint Inflammation And Destruction Via Er Stress In Collagen Induced Arthritis Major achievement

ORS 2015 Annual Meeting  2015.3 

The IL-33/ST2 axis on mast cells contributes to protective immune responses to herpes simplex virus-2 Major achievement

The 39th Annual Meeting of the Japanese Society for Investigative Dermatology  2014.12 

The IL-33/ST2 axis on mast cells contributes to protective immune responses to herpes simplex virus-2. Major achievement

International Mast Cell and Basophill Meeting 2014  2014.12 

Temporal regulation of allergic reaction by the circadian clock.アレルギーと概日時計. Major achievement

2014.11 

授乳婦への乳酸菌・ビフィズス菌投与による母乳成分への影響. Major achievement

中尾　篤人,石丸　かよ子,福留博文,渡辺汐美,中埜拓

日本食品免疫学会設立10周年記念学術大会  2014.10 

マウスグリオーマモデルにおけるインドールアミン2,3ジオキシゲナーゼ阻害による抗腫瘍効果 Major achievement

埴原　光人,川瀧　智之,三塚　健太郎,大岡　杏子,荻原　雅和,中尾　篤人,木内　博之

日本脳神経外科学会第73回学術総会  2014.10 

アレルギー疾患発症予防と母乳中TGF-β ～母親の乳酸菌摂取の可能性～. Major achievement

中尾　篤人

第55回日本母性衛生学会総会  2014.9 

The IL-33-ST2 pathway derives mast cell-dependent antiviral responses Major achievement

44th ANNUAL DR MEETING ESDR  2014.9 

「アレルギーと体内時計」

中尾篤人

第15回京都アレルギークロストーク  2014.2 

Circadian clock regulates the expression levels of tight junction proteins, permeability, and barrier function in the intestine. Major achievement

第42回日本免疫学会  2013.12 

マスト細胞の内在時計によるIgE受容体の日内変動の調節. Major achievement

第63回日本アレルギー学会秋季学術大会  2013.11 

Circadian regulation of allergic reaction by the mast cell clock. Major achievement

2013 Asia Pacific Congress of Allergy, Asthma, and Clinical Immunology (APCAAI)  2013.11 

マスト細胞の内在時計によるアレルギー反応の日内変動の調節. Major achievement

第20回日本時間生物学会学術大会  2013.11 

母乳中TGF-βは乳幼児アレルギー疾患の防御因子か? Major achievement

第9回日本食品免疫学会  2013.10 

Prevention of food allergy by dietary resveratrol. Major achievement

Resveratrol 2013 Regional Meeting.  2013.10 

Prevention of food allergy by dietary resveratrol. Major achievement

Resveratrol 2013 Regional Meeting.  2013.10 

免疫グロブリン、IgEや特異IgEを中心に-体内時計によるIgE応答の時間的制御- Major achievement

中尾　篤人

第33回六甲カンファレンス  2013.7 

免疫療法の新たな展開 作用機序について Major achievement

中尾　篤人

第25回日本アレルギー学会春季臨床大会  2013.5 

Circadian regulation of allergic reaction by the mast cell clock. Major achievement

2013.3 

「融合研究の推進」～共同研究や臨床応用への可能性～ Major achievement

中尾　篤人

山梨大学 融合研究臨床応用推進センター第2回講演会  2013.3 

TWEAKは変形性関節症の関節液中に存在し、軟骨分化を抑制する Major achievement

安藤　隆,渡邉　義孝,市川　二郎,若生　政憲,大北　弦樹,藤田　康稚,齋藤　正憲,中尾　篤人,波呂　浩孝

第26回日本軟骨代謝学会  2013.3 

レスベラトロールによるマウスの加齢性椎間板変性の予防効果 Major achievement

藤田　康稚,安藤　隆,市川　二郎,大北　弦樹,齋藤　正憲,中尾　篤人,波呂　浩孝

第26回日本軟骨代謝学会  2013.3 

アレルギーと体内時計 Major achievement

中尾　篤人

第21回大分アレルギー講習会  2013.2 

IL-33 triggers mast cell-mediated innate immunity against lethal herpes simplex virus infection through TNF-α and IL-6 Major achievement

The 37th Annual Meeting of the Japanese Society for Investigative Dermatology  2012.12 

TSLPとアレルギー Major achievement

中尾　篤人

第62回日本アレルギー学会秋季学術大会  2012.11 

マスト細胞の内在時計による即時型皮膚反応の日内変動の調節 Major achievement

中村勇規,中尾　篤人,柴田　重信

第62回日本アレルギー学会秋季学術大会  2012.11 

関節リウマチとTGF-β Major achievement

2012.10 

MMP-3の椎間板分解能における加齢の影響について Major achievement

藤田　康稚,大場　哲郎,若生　政憲,安藤　隆,中尾　篤人,波呂　浩孝

第27回日本整形外科学会基礎学術集会  2012.10 

Colostrum feeding and immunological substance in colostrum among lactating women from urban and rural environments, Nepal. Major achievement

44th Asia-Pacific Academic Consortium for Public Health  2012.10 

グリオーマにおけるIDO(Indoleamine 2,3-dioxygenase)の発現とIDO阻害による抗腫瘍効果 Major achievement

埴原　光人,川瀧　智之,三塚　健太郎,大岡　杏子,荻原　雅和,佐藤　浩企,堀越　徹,中尾　篤人,木内　博之

第13回日本分子脳神経外科学会  2012.9 

IL-33 triggers mast cell-mediated innate immunity against lethal herpes simplex virus infection through TNF-α and IL-6 Major achievement

42ND ANNUAL ESDR MEETING  2012.9 

マスト細胞の内在時計による即時型皮膚反応の日内変動の調節 Major achievement

中村　勇規,中尾　篤人,柴田　重信

第14回応用薬理シンポジウム  2012.9 

アレルギーと体内時計 Major achievement

中尾　篤人

第14回応用薬理シンポジウム  2012.9 

アレルギーと体内時計 Major achievement

中尾　篤人

ifia JAPAN2012(第17回国際食品素材/添加物展・会議、HFE JAPAN 2012(第10回ヘルスフードエキスポ)  2012.5 

Circadian clock gene Period2 regulates a time-of-day-dependent variation in cutaneous anaphylactic reaction Major achievement

2012.3 

Age-related of MCP-1 and MMP-3 expression in intervertebral disc in relation to inflammatory cytokine stimulation Major achievement

Kohji FUJITA,Takashi ANDO,Tetsuroh OHBA,Masanori WAKOU,Ryohei KATOH,Atsuhito NAKAO,Hirotaka HARO

ORS 2012 Annual Meeting  2012.2 

Circadian clock gene Peropd2 regulates large intestinal barrier function. Major achievement

Kyoko Oh-oka,Atsuhito NAKAO

2011.12 

Severe irritant contact dermatitis with loss of Langerhans cells in a mouse model of acrodermatitis enteropathica Major achievement

Tatsuyoshi Kawamura,Youichi Ogawa,Yuumi Nakamura,Akashi Izumi,Hajime Nakano,Schuichi KOIZUMI,Tatsuhiko Komada,Atsuhito NAKAO,Shinji Shimada

The 36th Annual Meeting of the Japanese Society for investigative Dermatology Kyoto  2011.12 

The circadian clock gene Period2 regulates a daily rhythm in cutaneous anaphylactic reaction. Major achievement

Atsuhito NAKAO

2011.11 

Period2 regulates intestinal barrier function. Major achievement

Kyoko OH-OKA,Ko OKUMURA,Atsuhito NAKAO

2011.11 

Functional analysis of tumor filtrating CD8+ T cells in liver metastasis. Major achievement

Naomi SHIMOKAWA,Ryusuke NAKAGAWA,Atsuhito NAKAO

2011.11 

体内時計システムによる即時型皮膚反応の日内変動の調節 Major achievement

中村　勇規,中尾　篤人,柴田　重信

第18回日本時間生物学会学術大会  2011.11 

マウス食物アレルギーモデルに対するレスべラトロールの効果 Major achievement

岡田　祐依,奥田　徹,中尾　篤人

第61回日本アレルギー学会秋季学術大会  2011.11 

体内時計システムによる即時型皮膚反応の日内変動の調節 Major achievement

中村　勇規,中尾　篤人

第61回日本アレルギー学会秋季学術大会  2011.11 

母乳中TGF-βは,乳幼児のアレルギー疾患を予防するカギか? Major achievement

中尾　篤人

第61回日本アレルギー学会秋季学術大会  2011.11 

(教育講演)アレルギーと体内時計 Major achievement

中尾　篤人

第61回日本アレルギー学会秋季学術大会  2011.11 

アレルギーとは何か? Major achievement

中尾　篤人

エコチル山梨 フォーラム2011秋  2011.11 

The biological clock regulates allergic reaction. Major achievement

Atsuhito NAKAO

The 1st University of Yamanashi Global COE Meeting 2011  2011.9 

Dysfuncion of the circadian gene Period2 protects mice against DSS-induced colitis. -Period2 regulates intestinal barrier function- Major achievement

Kyoko Oh-oka,Atsuhito NAKAO

15th International Congress of Mucosal Immunology  2011.7 

椎間板ヘルニアの自然退縮機構および椎間板変性に対する老化の影響について Major achievement

藤田　康稚,安藤　隆,大場　哲郎,若生　政憲,中尾　篤人,波呂　浩孝

第40回日本脊椎脊髄病学会  2011.4 

母乳中の免疫制御サイトカインTransforming Growth Factor(TGF)-β濃度に影響を与える要因:中間分析結果 Major achievement

近藤　尚己,須田　由紀,中尾　篤人,鈴木　孝太,佐藤　美理,田中　太一郎,永井　亜貴子,山縣　然太朗,大霜かよ子

日本疫学会  2011.1 

Age-related sequences of mcp-1 and mmp-3 expression in degeneration of mouse intervertebral disc Major achievement

Kohji FUJITA,Takashi ANDO,Tetsuroh OHBA,Masanori WAKO,Yasushi HARA,Ryohei KATOH,Atsuhito NAKAO,Hirotaka HARO

Orthopaedic Research Society  2011.1 

乳幼児アレルギー疾患の発症抑制と母乳中TGF-β Major achievement

中尾　篤人

第47回日本小児アレルギー学会  2010.12 

Period2遺伝子による即時型皮膚過敏反応の日内変動の調節 Major achievement

中尾　篤人,中村　勇規

第60回日本アレルギー学会秋季学術大会  2010.11 

Period2遺伝子による即時型皮膚過敏反応の日内変動の調節 Major achievement

中尾　篤人,中村　勇規,柴田　重信

第17回日本時間生物学会学術大会  2010.11 

TGF-βシグナルとアレルギー疾患 Major achievement

中尾　篤人

第64回日本臨床眼科学会  2010.11 

ヘルニア塊の退縮に対する加齢の影響について Major achievement

藤田　康稚,大場　哲郎,安藤　隆,若生　政憲,中尾　篤人,波呂　浩孝

第25回日本整形外科学会基礎学術集会  2010.10 

椎間板細胞における炎症性反応の加齢による変化 Major achievement

藤田　康稚,安藤　隆,大場　哲郎,若生　政憲,加藤　良平,中尾　篤人,波呂　浩孝

第29回日本運動器移植・再生医学研究会  2010.9 

Aryl hydrocarbon receptor signaling and colitis. Major achievement

Atsuhito NAKAO

The 1st University of Yamanashi Global COE Meeting 2010  2010.9 

Aryl hydrocarbon receptor経路の活性化によるデキストラン硫酸ナトリウム誘導性大腸炎の抑制 Major achievement

高村　武之,原間　大輔,下川　直美,北村　正敬,中尾　篤人

第47回日本消化器免疫学会総会  2010.7 

Mechanisms underlying upregulation of microglial P2Y6 receptors after kainic acid treatment. Major achievement

藤下　加代子,中尾　篤人,井上　和秀,小泉　修一

第83回日本薬理学会  2010.3 

Activation of aryl hydrocarbon receptor ameliorates experimental colitis in mice. Major achievement

Atsuhito NAKAO

The 2nd University of Yamanashi Global COE Meeting 2009  2010.1 

大腸菌由来毒素であるSubABは、UPRを惹起することでLPS誘導性の炎症反応を抑制する. Major achievement

原間　大輔,中尾　篤人,下川　直美

第39回日本免疫学会総会・学術集会  2009.12 

TGF-βの経口投与によるアレルギー疾患の予防 Major achievement

中尾　篤人

第64回臨床アレルギー研究会  2009.11 

TSLPは、腰椎椎間板ヘルニアの自然退縮機序において、MCP-1を介して、ヘルニア塊へのマクロファージの浸潤に作用している Major achievement

大場　哲郎,波呂　浩孝,若生　政憲,安藤　隆,藤田　康稚,中尾　篤人

第24回日本整形外科学会基礎学術集会  2009.11 

TGF-βの経口投与によるアレルギー疾患の予防 Major achievement

中尾　篤人

第73回日本皮膚科学会東部支部学術大会 スポンサードシンポジウム1  2009.9 

Mechanisms underlying upregulation of P2Y6 receptors in microglia in kainate-induced injury model Major achievement

Kayoko FUJISHITA,Atsuhito NAKAO,Kazuhide　Inoue,Schuichi KOIZUMI

Euroglia  2009.9 

Mechanisms underlying upregulation of P2Y6 receptors in microglia in kainate-induced injury model Major achievement

Kayoko FUJISHITA,Atsuhito NAKAO,Kazuhide　Inoue,Schuichi KOIZUMI

IUPS  2009.7 

Neuron-microglia interaction mediated by multiple P2Y receptors. Major achievement

Schuichi KOIZUMI,Kayoko FUJISHITA,Atsuhito NAKAO,Kazuhide　Inoue

IUPS  2009.7 

House dust mite allergen Der f 1 can activate latent TGF-β, leading to the expression of profibrogenic genes. Major achievement

中尾　篤人

8th Pan-Pacific Connective Tissue Societies Symposium  2009.6 

Mechanisms underlying upregulation of P2Y6 receptors in microglia in kainate-induced injury model. Major achievement

Kayoko FUJISHITA,Atsuhito NAKAO,Schuichi KOIZUMI

2009.3 

TSLPは,腰椎椎間板ヘルニアの自然退縮機序において,MCP-1を介して,ヘルニア塊へのマクロファージの浸潤に作用している Major achievement

大場　哲郎,波呂　浩孝,若生　政憲,藤田　康稚,中尾　篤人,濵田　良機

第22回日本軟骨代謝学会  2009.3 

ぜんそく発作はなぜ夜間に多いのか?」-体内時計とアレルギーの関係を解明する- Major achievement

中尾　篤人

文部科学省戦略的大学連携支援事業<学術シンポジウム>山梨大学・早稲田大学:国私立大学間連携による医学・  2009.2 

Cigarette smoke extract induces TSLP expression, leading to Th2-type immune responses and airway inflammation. Major achievement

Atsuhito NAKAO

University of Yamanashi Global COE Program International Symposium  2009.1 

Role of a transcription factor GATA-1 in commitment between dentritic cells and mast cells. Major achievement

Naomi SHIMOKAWA,Chiharu Nishiyama,Atsuhito NAKAO,Ko Okumura,Hideoki Ogawa

2008.12 

Cigarette smoke extract induce TSLP expression ,leading to allergic airway inflammation. Major achievement

Yuki Nakamura,Masanori MIYATA,Naomi SHIMOKAWA,Ｈｉｄｅｏｋｉ　Ogawa,Atsuhito NAKAO

2008.11 

ミクログリアP2Y6受容体発現亢進の分子メカニズム Major achievement

藤下　加代子,中尾　篤人,小泉　修一

グリア研究会  2008.11 

TWEAKが椎間板に及ぼす変性作用のメカニズム解明とその阻害による効果について Major achievement

若生　政憲,波呂　浩孝,大場　哲郎,安藤　隆,中尾　篤人,濵田　良機

第23回日本整形外科学会基礎学術集会  2008.10 

地域農産素材等の機能性解明と高付加価値製品の開発 Major achievement

竹丘　守,石井　利幸,藤木　俊也,上野　直也,恩田　匠,小嶋,長沼　孝多,斎藤　美貴,橋本　卓也,伊藤　和彦,保倉勝己,中尾　篤人,廣瀬　裕子

平成20年度やまなし産学官連携研究交流事業 産学官の知が生み出す地域イノベーション  2008.9 

アレルギーの新規予防法: TGF-βの経口投与 Major achievement

中尾　篤人

第4回日本免疫学会(JSI)-理研免疫アレルギーセンター(RCAI)免疫ワークショップ  2008.5 

Orally administered TGF-β is biologically active in the intestinal mucosa and enhances oral tolerance. Major achievement

Atsuhito NAKAO

Second Japanese-French Frontiers of Science Symposium  2008.1 

Role of a transcription factor GATA-1 in commitment between dentritic cells and mast cells. Major achievement

Naomi SHIMOKAWA,Chiharu Nishiyama,Atsuhito NAKAO,Ko Okumura,Hideoki Ogawa

2007.11 

アレルギー性鼻炎モデルマウスにおけるTSLPの発現 Major achievement

宮田　政則,下川　直美,小川　秀興,奥村　康,増山　敬祐,中尾　篤人

第57回日本アレルギー学会秋季学術大会  2007.11 

ヨーグルトによるアレルギー反応抑制の機序:含有するTGF-βの効果 Major achievement

末永文子,下川　直美,小川　秀興,中尾　篤人

第57回日本アレルギー学会秋季学術大会  2007.11 

TWEAKによる椎間板変性促進作用 Major achievement

若生　政憲,波呂　浩孝,大場　哲郎,安藤　隆,中尾　篤人,濵田　良機

第22回日本整形外科学会基礎学術集会  2007.10 

椎間板由来のサイトカイン産生におけるTNF-αのシグナル伝達経路の解析 Major achievement

大場　哲郎,波呂　浩孝,安藤　隆,若生　政憲,中尾　篤人,濵田　良機

第22回日本整形外科学会基礎学術集会  2007.10 

イマチニブはタイプ2コラーゲン抗体による関節炎を抑制する Major achievement

小山　賢介,杉山　肇,濵田　良機,中尾　篤人

第22回日本整形外科学会基礎学術集会  2007.10 

関節リウマチにおける胸腺間質性リンパ球新生因子(TSLP)の役割 Major achievement

小山　賢介,杉山　肇,濵田　良機,中尾　篤人

第22回日本整形外科学会基礎学術集会  2007.10 

アレルギー疾患の新しい予防法:TGF-βの経口投与 Major achievement

中尾　篤人

新技術説明会「イノベーションジャパン2007」  2007.9 

TGF-βの経口投与によるアレルギー性疾患の予防 Major achievement

中尾　篤人

産学交流ネットワーク2007  2007.8 

Orally administered TGF-β is biologically active in the intestinal mucosa and enhances oral tolerance Major achievement

Atsuhito NAKAO,Takashi ANDOH,Kyousuke HATSUSHIKA,Wako MASANORI,Yuko Ohnuma,Hideoki OGAWA,Ki OKUMURA,Tony WYSS-CORAY

13th International Congress of Mucosal Immunology  2007.7 

TWEAKによる椎間板由来MMP-3の誘導 Major achievement

若生　政憲,波呂　浩孝,安藤　隆,中尾　篤人,濵田　良機

第36回日本脊椎脊髄病学会  2007.4 

Blockade of endogenous TGF-β signaling promotes differetiation of dendritic cells that produce IL-13 and augments Th2 cell polarization Major achievement

Masao Furuhashi,Shinji Shimada,Atsuhito NAKAO

2007.4 

TWEAKを介した気道上皮細胞ー好酸球の細胞間相互作用の検討 Major achievement

岡本　篤司,松岡　伴和,森山　元大,中尾　篤人,増山　敬祐

第25回日本耳鼻咽喉科免疫アレルギー学会  2007.3 

アレルギー性鼻炎モデルマウスにおけるTGFβ2発現機序と気道リモデリング形成における役割についての解析 Major achievement

初鹿　恭介,中尾　篤人,増山　敬祐

第25回日本耳鼻咽喉科免疫アレルギー学会  2007.3 

TGF-βシグナルと免疫アレルギー疾患 Major achievement

中尾　篤人

第25回日本耳鼻咽喉科免疫アレルギー学会  2007.3 

ヒト好酸球におけるTGF-β/Smadシグナル伝達機構の解析 Major achievement

神崎　美玲,柴垣　直孝,三井　広,猪爪　隆史,島田　眞路,岡本　篤志,土橋　洋,中尾　篤人,小川　秀興

第56回日本皮膚科学会山梨地方会  2006.11 

TGF-β型受容体キナーゼ阻害剤は2型コラーゲン抗体によって誘導される関節炎を抑制する Major achievement

佐久間　陸友,杉山　肇,濵田　良機,安藤　隆,中尾　篤人

第21回日本整形外科学会基礎学術集会  2006.10 

RA滑膜線維細胞はTGF-β刺激により炎症性サイトカインを産生する Major achievement

佐久間　陸友,杉山　肇,渡邉　義孝,若生　政憲,安藤　隆,中尾　篤人,濵田　良機

第55回東日本整形災害外科学会  2006.9 

Transforming growth factor-β/Smad signaling is functional in human eosinophis Major achievement

Mirei Kanzaki,Naotaka Shibagaki,Hiroshi Mitsui,Takashi Inozume,Atsushi Okamoto,Hiroshi Dobashi,Hideoki Ogawa,Shinji Shimada,Atsuhito NAKAO

2006.9 

軟骨におけるTWEAKの役割 Major achievement

渡邉　義孝,中尾　篤人,安藤　隆,佐久間　陸友,若生　政憲,杉山　肇,濵田　良機

第18回中部リウマチ学会  2006.9 

TGF-βの経口投与によるアレルギー疾患の予防と治療 -機能性食品や医薬品への応用- Major achievement

中尾　篤人

第3回CIC新技術説明会  2006.7 

TGF-βSMAD SIGNALING IS FUNCTIONAL IN HUMAN EOSINOPHILS Major achievement

Mirei Kanzaki,Naotaka Shibagaki,Hiroshi Mitsui,Takashi Inozume,Atsushi Okamoto,Yoh DOBASHI,Hideoki Ogawa,Shinji Shimada,Atsuhito NAKAO

2006.5 

変形性関節症におけるTWEAKの役割 Major achievement

渡邉　義孝,安藤　隆,佐久間　陸友,若生　政憲,中尾　篤人,濵田　良機

第79回日本整形外科学会学術総会  2006.5 

Sjppression of serum IgE response and systemic anaphylaxis in a food allergy model by orally administered high-dose TGF-beta. Major achievement

Atsuhito NAKAO

TGF-beta meeting in Uppsala  2006.5 

Suppression of serum IgE responhse and systemic anaphylaxis in a food allergy model by orally administered high-dose TGF-beta. Major achievement

Atsuhito NAKAO

KEYSTONE SYMPOSIA, Allergy, Allergic Inflammation and Asthma  2006.4 

経口的な高用量TGF-beta投与による食物アレルギー反応の抑制 Major achievement

中尾　篤人,岡本　篤司,川村　龍吉,小川秀興,奥村　康

第55回日本アレルギー学会秋期学術大会  2005.10 

TGF-βの経口投与による食物アレルギーの抑制 Major achievement

中尾　篤人

第13回小児気道アレルギー研究会  2005.9 

TGF-βによる骨肉腫細胞の増殖、転移誘導 Major achievement

市川　二郎,佐藤　栄一,河野　秀樹,安藤　隆,中尾　篤人,濵田　良機

第38回日本整形外科学会骨・軟部腫瘍学術集会  2005.7 

HER-2陽性食道扁平上皮癌細胞株におけるTrastuzumab療法とその増強の工夫 Major achievement

三村 耕作,河野　浩二,宮川 直登,小俣 秀雄,須貝　英光,神崎　美玲,中尾　篤人,藤井　秀樹

第60回日本消化器外科学会定期学術総会  2005.7 

HER 2陽性食道扁平上皮癌細胞株におけるTrastuzumab療法とその増強の工夫 Major achievement

三村 耕作,河野　浩二,宮川 直登,小俣 秀雄,須貝　英光,神崎　美玲,中尾　篤人,藤井　秀樹

第26回癌免疫外科研究会  2005.5 

BMP2による骨形成に対するTweakの抑制効果 Major achievement

市川　二郎,安藤　隆,佐藤　栄一,濵田　良機,田坂　捷雄,中尾　篤人

第19回日本整形外科学会基礎学術集会  2004.10 

第42回三島海雲記念財団学術奨励賞

2004.6   財団法人　三島海雲記念財団  

中尾　篤人

北陸製薬・アレルギー学術奨励賞

2001.10   北陸製薬  

中尾　篤人

アストラゼネカ喘息研究奨励賞

2001.1   アストラゼネカ  

中尾　篤人