Updated on 2024/05/01

写真a

 
Chihiro Imai
 
Organization
Graduate Faculty of Interdisciplinary Research Faculty of Education Human Science (Social Life Education) Associate Professor
Title
Associate Professor

Research History

  • 山梨大学大学院総合研究部   教育学域 生活社会教育講座   准教授

    2022.4

  • University of Yamanashi

    2017.2 - 2020.12

  • 東京医科歯科大学 難治疾患研究所   ゲノム応用医学部門 分子疫学分野   助教

    2016.4 - 2022.3

  • University of Shizuoka

    2015.4 - 2016.3

  • University of Shizuoka

    2014.4 - 2015.3

Education

  • University of Shizuoka

    2013.4 - 2016.3

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    Country: Japan

    Course: Doctor later

  • University of Shizuoka

    2011.4 - 2013.3

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    Country: Japan

    Course: Doctor prophase

  • University of Shizuoka

    2007.4 - 2011.3

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    Country: Japan

    Course: Others

Degree

  • 博士(薬食生命科学) ( 2016.3   静岡県立大学 )

  • 修士(食品栄養科学) ( 2013.3   静岡県立大学 )

Research Areas

  • Humanities & Social Sciences / Family and consumer sciences, and culture and living

  • Life Science / Nutrition science and health science

Research Interests

  • エピジェネティクス

  • 栄養疫学

  • 食生活学

  • 栄養学

Research Projects

  • 栄養学と教育学融合による食行動変容研究の基盤形成

    2023.6 - 2024.3

    山梨大学  萌芽研究トライアル  萌芽研究トライアル

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    Authorship:Principal investigator  Grant type:Competitive  Type of fund::Joint research

  • 発育期低栄養に起因する消化管ホルモンエピゲノム異常と慢性炎症との関連

    Grant number:23K10911  2023.4 - 2026.3

    日本学術振興会  科学研究費助成事業  2023年度 基盤研究(C)

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    Authorship:Principal investigator  Grant type:Competitive  Type of fund::Science research expense

  • 学びの世代におけるDOHaD学説(健康と病気の発育期起源学説)に根差した山梨県食教育アプローチの基盤形成

    2022.7 - 2023.2

    山梨大学 男女共同参画推進室  ダイバーシティ研究環境実現イニシアティブ  ダイバーシティ研究環境実現イニシアティブ(牽引型)

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    Authorship:Principal investigator  Type of fund::Joint research

  • 妊娠中の栄養・生活環境要因の母児エピゲノムへの影響と妊娠経過および予後との関連

    Grant number:20K19635  2020.4 - 2024.3

    日本学術振興会  科学研究費助成事業  若手研究

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    Authorship:Principal investigator  Type of fund::Science research expense

  • 発育期・成人期の食習慣によるGene bodyエピゲノムの撹乱と代謝疾患発症

    Grant number:20H04103  2020.4 - 2023.3

    日本学術振興会  科学研究費助成事業  基盤研究(B)

    望月和樹

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    Authorship:Coinvestigator(s)  Type of fund::Science research expense

  • 妊娠中のエピゲノム変化を起こす栄養・生活環境要因と母児の健康指標との関連

    Grant number:17K12896  2017.4 - 2020.3

    日本学術振興会  科学研究費助成事業  若手研究(B)

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    Authorship:Principal investigator  Type of fund::Science research expense

  • 発育期低栄養および食環境で獲得されるエピゲノム変化による消化管機能の撹乱

    Grant number: 16H06764  2016.8 - 2018.3

    日本学術振興会  科学研究費助成事業  研究活動スタート支援

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    Authorship:Principal investigator  Type of fund::Science research expense

  • 食後高血糖の繰り返しによるエピゲノムの蓄積と炎症の慢性化に関する研究

    Grant number:15J06391  2015.4 - 2016.3

    日本学術振興会  科学研究費助成事業  特別研究員奨励費

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    Authorship:Principal investigator  Type of fund::Science research expense

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Papers

  • Diet quality and its relationship with weight characteristics in pregnant Japanese women: A single-center birth cohort study Reviewed

    Chihiro Imai, Hidemi Takimoto, Kayo Kurotani, Ayako Fudono, Iori Tarui, Tomoko Aoyama, Satoshi Yago, Motoko Okamitsu, Naoyuki Miyasaka, Noriko Sato

    Nutrients   15 ( 8 )   1827   2023.4

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/nu15081827.

  • Trimester-specific associations between extracellular vesicle microRNAs and fetal growth Reviewed

    Ayako Fudono, Chihiro Imai, Hidemi Takimoto, Iori Tarui, Tomoko Aoyama, Satoshi Yago, Motoko Okamitsu, Masaaki Muramatsu, Noriko Sato, Naoyuki Miyasaka

    Journal of Maternal-Fetal & Neonatal Medicine   2021.11( ISSN:1476-7058 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Journal of Maternal-Fetal & Neonatal Medicine  

  • Placenta mediates the effect of maternal hypertension polygenic score on offspring birth weight: a study of birth cohort with fetal growth velocity data Reviewed

    Noriko Sato, Ayako Fudono, Chihiro Imai, Hidemi Takimoto, Iori Tarui, Tomoko Aoyama, Satoshi Yago, Motoko Okamitsu, Shuki Mizutani, Naoyuki Miyasaka

    BMC Medicine   19 ( 1 )   1 - 13   2021.11( ISSN:1741-7015 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:BMC Medicine  

  • Application of the Nutrient-Rich Food Index 9.3 and the Dietary Inflammatory Index for Assessing Maternal Dietary Quality in Japan: A Single-Center Birth Cohort Study Reviewed

    Chihiro Imai, Hidemi Takimoto, Ayako Fudono, Iori Tarui, Tomoko Aoyama, Satoshi Yago, Motoko Okamitsu, Satoshi Sasaki, Shuki Mizutani, Naoyuki Miyasaka, Noriko Sato

    Nutrients   13 ( 8 )   1 - 17   2021.8

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Nutrients  

  • The utility of post-test newborn blood spot screening cards for epigenetic association analyses: association between HIF3A methylation and birth weight-for-gestational age Reviewed

    Tay Zar Kyaw, Seiji Yamaguchi, Chihiro Imai, Marina Uematsu, Noriko Sato

    JOURNAL OF HUMAN GENETICS   64 ( 8 )   795 - 801   2019.8( ISSN:1434-5161 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:JOURNAL OF HUMAN GENETICS  

  • Metabolic and Immunological Shifts during Mid-to-Late Gestation Influence Maternal Blood Methylation of CPT1A and SREBF1 Reviewed

    Shilpa Pavethynath, Chihiro Imai, Xin Jin, Naomi Hichiwa, Hidemi Takimoto, Motoko Okamitsu, Iori Tarui, Tomoko Aoyama, Satoshi Yago, Ayako Fudono, Masaaki Muramatsu, Naoyuki Miyasaka, Noriko Sato

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   20 ( 5 )   1 - 14   2019.5( ISSN:1422-0067 )

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:International Journal of Molecular Sciences  

  • The Role of Epigenetics in Developmental Programming and the Developmental Origins of Health and Disease Reviewed

    Kazuki Mochizuki, Chihiro Imai, Noriko Sato, Takeo Kubota

    OBM Genetics   1 ( 4 )   1 - 15   2017.10

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:OBM Genetics  

  • Early gestational maternal low-protein diet diminishes hepatic response to fasting in young adult male mice Reviewed

    Noriko Sato, Katsuko Sudo, Masayo Mori, Chihiro Imai, Masaaki Muramatsu, Masahiro Sugimoto

    Scientific Reports   7 ( 1 )   1 - 13   2017.8( ISSN:2045-2322 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Scientific Reports  

  • Relation between chronic inflammation induced by accumulation of postprandial hyperglycemia and development of type 2 diabetes

    2016.3

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    Authorship:Lead author, Last author, Corresponding author   Language:Japanese   Publishing type:Doctoral Thesis  

  • Treatment with DPP-4I Anagliptin or α-GI Miglitol Reduces IGT Development and the Expression of CVD Risk Factors in OLETF Rats Reviewed

    Chihiro Imai, Tomomi Harazaki, Seiya Inoue, Kazuki Mochizuki, Toshinao Goda

    JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY   61 ( 4 )   313 - 321   2015.10( ISSN:0301-4800 )

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY  

  • Cotreatment with the alpha-glucosidase inhibitor miglitol and DPP-4 inhibitor sitagliptin improves glycemic control and reduces the expressions of CVD risk factors in type 2 diabetic Japanese patients Reviewed

    Chihiro Imai, Miyoko Saito, Kazuki Mochizuki, Masahiro Fuchigami, Toshinao Goda, Takeshi Osonoi

    METABOLISM-CLINICAL AND EXPERIMENTAL   63 ( 6 )   746 - 753   2014.6( ISSN:0026-0495 )

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Metabolism  

  • Resistant starch improves insulin resistance and reduces adipose tissue weight and CD11c expression in rat OLETF adipose tissue Reviewed

    Tomomi Harazaki, Seiya Inoue, Chihiro Imai, Kazuki Mochizuki, Toshinao Goda

    NUTRITION   3 ( 5 )   590 - 595   2014.5( ISSN:0899-9007 )

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Resistant starch improves insulin resistance and reduces adipose tissue weight and CD11c expression in the adipose tissues of OLETF rats Reviewed

    Toshinao Goda, Tomomi Harazaki, Seiya Inoue, Chihiro Imai, Kazuki Mochizuki

    FASEB JOURNAL   28 ( 1 )   2014.4( ISSN:0892-6638  eISSN:1530-6860 )

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    Language:English   Publishing type:(MISC) Summary of the papers read (international conference)   Publisher:FEDERATION AMER SOC EXP BIOL  

    Web of Science

  • Inhibition of postprandial hyperglycemia by either an insulin-dependent or -independent drug reduces the expression of genes related to inflammation in peripheral leukocytes of OLETF rats Reviewed

    Chihiro Imai, Tomomi Harazaki, Seiya Inoue, Kazuki Mochizuki, Toshinao Goda

    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY   77 ( 11 )   2305 - 2308   2013.11( ISSN:0916-8451 )

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  • Reducing the risk of the cardiovascular diseases through regulating gene expression in peripheral leukocytes by suppression of postprandial hyperglycemia in type 2 diabetes

    2013.3

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    Authorship:Lead author, Last author, Corresponding author   Language:Japanese   Publishing type:Master Thesis  

  • ミグリトールまたはシタグリプチン単剤による治療で効果不十分な2型糖尿病患者における両剤併用療法の効果 Reviewed

    遅野井健、斎藤三代子、望月和樹、今井千裕、合田敏尚

    診療と新薬 第48巻 第5号   48 ( 5 )   471 - 482   2011.5

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:医事出版社  

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Books and Other Publications

  • DOHaD 先制医療への展開

    今井千裕, 望月和樹, 佐田 文宏, 福岡 秀興( Role: Contributor)

    金原出版  2023.5 

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    Total pages:316   Responsible for pages:4   Language:Japanese   Book type:Scholarly book

Presentations

  • 糖シグナルによる慢性炎症促進と2型糖尿病-モデル動物およびヒトでの検証-

    今井千裕

    第46回日本分子生物学会年会  2023.12 

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    Event date: 2023.12

    Language:Japanese   Presentation type:Symposium workshop panel(public)  

    Venue:神戸  

  • 大学生を対象とした次世代の健康を包括した食教育基盤形成のための意識調査

    今井千裕、望月和樹

    第77回日本栄養・食糧学会大会  2023.5 

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    Event date: 2023.5

    Language:Japanese   Presentation type:Poster presentation  

    Venue:札幌  

  • 次世代の健康を包括した食教育に向けての現状と課題

    今井千裕

    女性研究者研究報告会 ダイバーシティが牽引する地域活性化とイノベーション  2023.1  山梨大学男女共同参画推進室/地域人材養成センター

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    Event date: 2023.1

    Language:Japanese   Presentation type:Poster presentation  

    Venue:甲府  

  • A prudent Japanese dietary pattern is associated with a reduced risk of metabolic diseases predicted by principal component analysis of the clinical parameters related to metabolic syndrome. International conference

    22nd IUNS International Congress of Nutrition  2022.12 

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    Event date: 2022.12

    Language:English   Presentation type:Oral presentation(general)  

    Venue:Tokyo, Japan  

  • 妊娠期の栄養の適正化への専門職の取り組みを考える(次世代の健康を守る-胎児期栄養支援・啓発委員会)「妊娠期の食事の質の評価と妊娠準備世代における食教育の意義」 Invited

    今井千裕

    第44回日本臨床栄養学会総会・第43回日本臨床栄養協会総会・第20回大連合大会  2022.10 

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    Event date: 2022.10

    Language:Japanese   Presentation type:Symposium workshop panel(public)  

    Venue:盛岡  

  • Nutrient-Rich Food IndexおよびDietary Inflammatory Indexを用いた妊婦の食事の質の解析

    第75回日本栄養・食糧学会大会  2021.7 

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    Event date: 2021.7

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:オンライン  

  • Perinatal maternal mental health, sleep quality, and infant development: A Japanese prospective cohort study International conference

    17th WAIMH WORLD CONGRESS  2021.6 

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    Event date: 2021.6

    Language:English   Presentation type:Poster presentation  

    Venue:Online  

  • 妊婦のたんぱく質エネルギー比率と新生児DNAメチル化-疾患関連メチル化部位の解析

    第74回日本栄養・食糧学会大会  2020.9 

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    Event date: 2020.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:オンライン  

  • Handgrip Strength in One-Month-Old Infants: How Strong Are They? International conference

    Perinatal Society of Australia & New Zealand  2020.4 

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    Event date: 2020.4

    Language:English   Presentation type:Oral presentation(general)  

    Venue:Online  

  • Trimester Specific Difference in Exosomal MicroRNA Expression International conference

    DOHaD 2019  2019.10 

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    Event date: 2019.10

    Language:English   Presentation type:Poster presentation  

    Venue:Melbourne, Australia  

  • Intra- and Inter- individual Differences in CPT1A and SREBF1 Methylation of Maternal Leukocytes During Mid-to-Late Gestation International conference

    DOHaD 2019  2019.10 

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    Event date: 2019.10

    Language:English   Presentation type:Poster presentation  

    Venue:Melbourne, Australia  

  • 妊娠後半期の末梢血における脂質関連遺伝子のDNAメチル化

    第73回日本栄養・食糧学会  2019.5 

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    Event date: 2019.5

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:静岡  

  • 新生児におけるSKI遺伝子ADHD関連部位のDNAメチル化個人差

    第41回日本分子生物学会  2018.11 

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    Event date: 2018.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:横浜  

  • 妊娠による炎症関連遺伝子TNFのGene body領域DNAメチル化状態の変化

    第7回日本DOHaD学会学術集会  2018.8 

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    Event date: 2018.8

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:東京  

  • Associations between maternal mental health, nutrition, and neonatal outcomes in Japanese birth cohort International conference

    16th WAIMH WORLD CONGRESS  2018.5 

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    Event date: 2018.5

    Language:English   Presentation type:Poster presentation  

    Venue:Rome, Italy  

  • 妊娠中の環境要因が影響するエピゲノム変化と母児の健康指標との関連‐BC-GENIST‐

    第6回日本DOHaD学会学術集会  2017.8 

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    Event date: 2017.8

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京  

  • Dietary intakes from 3-day weighed dietary records among pregnant participants in the Birth Cohort - Gene and ENvironment Interaction Study of TMDU (BC-GENIST) International conference

    The 21st World Congress of Epidemiology (WCE2017)  2017.8 

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    Event date: 2017.8

    Language:English   Presentation type:Poster presentation  

    Venue:Saitama, Japan  

  • Dietary intakes and depressive symptoms among pregnant participants in the Birth Cohort - Gene and ENvironment Interaction Study of TMDU (BC-GENIST)

    第27回日本疫学会学術総会  2017.1 

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    Event date: 2017.1

    Language:Japanese   Presentation type:Poster presentation  

    Venue:甲府  

  • 包括的出生前コホート―母親のメンタルヘルスとその関連要因―

    第13回日本周産期メンタルヘルス学会学術集会  2016.11 

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    Event date: 2016.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京  

  • 大学附属病院における包括的母子コホート研究の試み

    第63回日本栄養改善学会学術総会  2016.9 

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    Event date: 2016.9

    Language:Japanese   Presentation type:Symposium workshop panel(public)  

    Venue:青森  

  • Cohort profile: Birth Cohort – Gene and Environment Interaction Study of TMDU (BC-GENIST)

    第5回日本DOHaD学会学術集会  2016.7 

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    Event date: 2016.7

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京  

  • 好中球エラスターゼ活性阻害剤の食後高血糖動物モデルへの投与は動脈硬化関連遺伝子の発現を低下させる

    第59回日本糖尿病学会年次学術集会  2016.5 

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    Event date: 2016.5

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:京都  

  • 新規エピゲノム因子Brd4を介した単回のグルコース応答性炎症関連遺伝子の発現持続機構

    第88回日本生化学会・分子生物学会合同大会  2015.12 

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    Event date: 2015.12

    Language:Japanese   Presentation type:Poster presentation  

    Venue:神戸  

  • Suppression of the vascular endothelial damage-related genes by inhibiting neutrophil elastase activity in type 2 diabetic model OLETF rats

    第20回静岡健康・長寿学術フォーラム  2015.10 

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    Event date: 2015.10

    Language:Japanese   Presentation type:Poster presentation  

    Venue:静岡  

  • 2型糖尿病自然発症OLETFラットへのアナグリプチンの長期投与は肝臓における白血球浸潤マーカーの発現を抑制する

    第58回日本糖尿病学会年次学術集会  2015.5 

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    Event date: 2015.5

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:下関  

  • Transient high glucose exposure promotes subsequent inductions of inflammation- related genes and the histone acetylation around the genes in human monocyte-like THP-1 cell

    第19回静岡健康・長寿学術フォーラム  2014.7 

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    Event date: 2014.7

    Language:Japanese   Presentation type:Poster presentation  

    Venue:沼津  

  • 短期間の高グルコース刺激がヒト単球様THP-1細胞の炎症関連遺伝子の発現に及ぼす影響

    第3回日本DOHaD学会学術集会  2014.7 

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    Event date: 2014.7

    Language:Japanese   Presentation type:Poster presentation  

  • DPP-4阻害剤およびα-GIの長期単独投与あるいは共投与による肝臓における酸化傷害の抑制

    第57回日本糖尿病学会年次学術集会  2014.5 

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    Event date: 2014.5

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:大阪  

  • Reduction of inflammatory-related risk factors in peripheral tissues by suppression of postprandial hyperglycemia in type 2 diabetic OLETF rats

    第18回静岡健康・長寿学術フォーラム  2013.11 

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    Event date: 2013.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:静岡  

  • Reduction of inflammation-related CVD risk factors in peripheral tissues by suppression of postprandial hyperglycemia in type 2 diabetic OLETF rats International conference

    IUNS 20th International Congress of Nutrition  2013.9 

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    Event date: 2013.9

    Language:English   Presentation type:Oral presentation(general)  

    Venue:Granada, Spain  

  • 食後血糖上昇の長期にわたる抑制は2型糖尿病自然発症モデルOLETFラットにおける大血管障害発症のリスク因子の発現を低下させる

    第67回日本栄養・食糧学会大会  2013.5 

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    Event date: 2013.5

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:名古屋  

  • DPP-4阻害剤またはα-GIの長期投与による大動脈における接着因子の遺伝子発現抑制

    第56回日本糖尿病学会年次学術集会  2013.5 

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    Event date: 2013.5

    Language:Japanese   Presentation type:Poster presentation  

    Venue:熊本  

  • Cotreatment of miglitol and sitagliptin reduces circulating proteins related to CVD in type 2 diabetic Japanese patients International conference

    9th IDF-WPR Congress / 4th AASD Scientific Meeting  2012.11 

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    Event date: 2012.11

    Language:English   Presentation type:Oral presentation(general)  

    Venue:Kyoto, Japan  

  • ミグリトールによる体重増加の抑制効果と脂肪組織におけるGIP受容体発現との関連

    第55回日本糖尿病学会年次学術集会  2012.5 

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    Event date: 2012.5

    Language:Japanese   Presentation type:Poster presentation  

    Venue:横浜  

  • DPP-4阻害剤またはαGIの長期投与による耐糖能の改善と末梢血白血球における炎症関連遺伝子の発現抑制

    第55回日本糖尿病学会年次学術集会  2012.5 

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    Event date: 2012.5

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:横浜  

  • レジスタントスターチによるインスリン抵抗性の改善と脂肪組織における白血球接着関連遺伝子発現の抑制

    第54回日本糖尿病学会年次学術集会  2011.5 

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    Event date: 2011.5

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:札幌  

  • DPP-4阻害剤およびαGIによる食後高血糖の抑制は末梢血白血球における炎症関連遺伝子発現を抑制する

    第54回日本糖尿病学会年次学術集会  2011.5 

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    Event date: 2011.5

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:札幌  

  • ミグリトールまたはシタグリプチンによる治療で効果不十分な2型糖尿病患者における両剤併用療法の効果

    第54回日本糖尿病学会年次学術集会  2011.5 

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    Event date: 2011.5

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:札幌  

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Teaching Experience (On-campus)

  • Introduction in Food Science Major achievement

    2023Year

  • Experiment in Food Science Major achievement

    2023Year

  • 教育の方法及び技術(情報通信機器の活用含む)

    2023Year  Type of subject:Common education (undergraduate)

  • 教職実践演習

    2023Year

  • 地域素材の教材化

    2023Year

  • Essence and Goals / Content Structure of Home Economics

    2023Year

  • The teaching contents of Home Economics(theory and principles)

    2023Year

  • Relay Seminars for Introduction to Each Discipline of the Faculty

    2023Year

  • Health Science I

    2023Year

  • The teaching contents of Home Economics(theory and principles)

    2023Year

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Professional Memberships

  • 日本DOHaD学会

  • 日本栄養・食糧学会