Life Science / Cardiology  / Circulatory organs internal medicine

神経免疫機構におけるミエロイド系細胞のオートファジーの役割

2021

古藤田 眞和

アミオダロンの鎮痛作用および感覚神経選択性の検証

2020.4 - 2023.3

国際共同研究加速基金（国際共同研究強化(A)）

古藤田　眞和

アミオダロンの鎮痛作用および感覚神経選択性の検証

2020.4 - 2023.3

国際共同研究加速基金（国際共同研究強化(A)）

Masakazu Kotoda

炎症性疼痛におけるマクロファージのオートファジ―機構の役割

2020.4 - 2022.3

若手研究

古藤田　眞和

炎症性疼痛におけるマクロファージのオートファジ―機構の役割

2020.4 - 2022.3

若手研究

Masakazu Kotoda

アミオダロンの脳保護作用の検証

2017.4 - 2020.3

日本学術振興会  日本学術振興会科研費  基金・基盤研究（C）

アミオダロンの脳保護作用の検証

2017.4 - 2020.3

日本学術振興会  日本学術振興会科研費  基金・基盤研究（C）

The Effects of Adrenaline and Vasopressin onPial Microvessels During Global Brain Ischemia-reperfusion Period in Rabbits.

Grant number：25462401  2013.4 - 2017.3

Japan Society for the Promotion of Science  University of Yamanashi  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

ASANO Nobumasa, ISHIYAMA Tadahiko, MASAMUNE Taishi, IWASHITA Hironobu, KOTODA Masakazu, IKEMOTO Koudai, KUMAKURA Yasutomo

Amiodarone provides long-lasting local anesthesia and analgesia in open-state mouse nociceptors Reviewed Major achievement

Masakazu Kotoda, Toru Matsuoka, Keiichi Wada, Selwyn Jayakar, Hirofumi Ino, Koji Kawago, Yasutomo Kumakura

Frontiers in Pharmacology   2022.3( ISSN：1663-9812 )

Short sleep duration on the night before surgery is associated with postoperative cognitive decline in elderly patients: a prospective cohort study Reviewed Major achievement

Takamino A, Kotoda M, Nakadate Y, Hishiyama S, Iijima T, Matsukawa T

Frontiers in Aging Neuroscience   2022.1( ISSN：1663-4365 )

Inhibition of inflammatory pain and cough by a novel charged sodium channel blocker. Reviewed

Tochitsky I, Jo S, Andrews N, Kotoda M, Doyle B, Shim J, Talbot S, Roberson D, Lee J, Haste L, Jordan SM, Levy BD, Bean BP, Woolf CJ.

BRITISH JOURNAL OF PHARMACOLOGY   2021.6( ISSN：0007-1188 )

Efficacy of Pilsicainide for Tachyarrythmias during Anesthesia : Report of Two Cases Reviewed

　   2020.5

Assessment of the potential for pathogen dispersal during high-flow nasal therapy Reviewed

Kotoda M, Hishiyama S, Mitsui K, Tanikawa T, Morikawa S, Takamino A, Matsukawa T.

JOURNAL OF HOSPITAL INFECTION   2020.4( ISSN：0195-6701 )

Effects of β 1-adrenergic Receptor Blockade on the Cerebral Microcirculation in the Normal State and During Global Brain Ischemia/Reperfusion Injury in Rabbits Reviewed

Nobumasa Asano, Sohei Hishiyama, Tadahiko Ishiyama, Masakazu Kotoda, Takashi Matsukawa

BMC Pharmacology & Toxicology   2020.2( ISSN：2050-6511 )

Left-Right and Upper–Lower Light Sensitivity Asymmetry in Visual Field Defects Caused by Pituitary Adenoma: A Retrospective Observational Study Reviewed

Kotoda Y, Kotoda M, Ogiwara M, Kinouchi H, Iijima H

Clinical Ophthalmology   2020.1

Amiodarone exacerbates brain injuries after hypoxic-ischemic insult in mice. Reviewed

Kotoda M, Hishiyama S, Ishiyama T, Mitsui K, Matsukawa T.

BMC NEUROSCIENCE   2019.12( ISSN：1471-2202 )

A novel charged sodium and calcium channel inhibitor active against neurogenic inflammation Reviewed

Lee S, Talbot S, Jo S, Zhang H, Kotoda M, Andrews N, Heckman L, Puopolo M, Liu P, Jain A, Jacquemont A, Lee J, Woolf C, Bean B

eLife   2019.11( ISSN：2050-084X )

Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module Reviewed

Munji R, Soung A, Weiner G, Sohet F, Semple B, Trivedi A, Gimlin K, Kotoda M, Korai M, Aydin S, Batugal A, Cabangcala A, Schupp P, Oldham M, Hashimoto T, Noble-Haeusslein L, Daneman R.

NATURE NEUROSCIENCE   2019.10( ISSN：1097-6256 )

Prediction of heparin induced hypotension during cardiothoracic surgery: A retrospective observational study Reviewed

Kotoda M, Ishiyama T, Nakajima H, Matsukawa T.

Anaesthesia, Pain & Intensive Care   2019.8

Analgesic effects of amiodarone in mouse models of pain Reviewed

Kotoda M, Ino H, Kumakura Y, Iijima T, Ishiyama T, Matsukawa T.

Journal of Pain Research   2019.6( ISSN：1178-7090 )

Sudden onset pacemaker-induced diaphragmatic twitching during general anesthesia Reviewed

Tanabe K, Kotoda M, Nakashige D, Mitsui K, Ikemoto K, Matsukawa T.

JA Clinical Reports   2019.6

Neuroprotective effects of neurotropin in a mouse model of hypoxic-ischemic brain injury Reviewed

Hishiyama S, Kotoda M, Ishiyama T, Mitsui K, Matsukawa T.

Journal of Anesthesia   2019.5( ISSN：0913-8668 )

Removal methods of rigid stylets to minimise adverse force and tracheal tube movement: a mathematical and in-vitro analysis in manikins Reviewed

Kotoda M, Oguchi T, Mitsui K, Hishiyama S, Ueda K, Kawakami A, Matsukawa T.

ANAESTHESIA   74 ( 8 )   1041 - 1046   2019.5( ISSN：0003-2409 )

Changes of cerebral regional oxygen saturation during pneumoperitoneum and Trendelenburg position under propofol anesthesia: a prospective observational study Reviewed

Matsuoka T, Ishiyama T, Shintani N, Kotoda M, Mitsui K, Matsukawa T.

BMC Anesthesiology   2019.5( ISSN：1471-2253 )

Potential Influences of Gut Microbiota on the Formation of Intracranial Aneurysm Reviewed

Hypertension   2019.2

Anesthetic Management of a Patient with Laryngeal Myoclonus : A Case Report Reviewed

　   2018.11

Successful epidural anesthesia in a patient with an extremely shallow epidural space: a case report Reviewed

Anaesthesia, Pain & Intensive Care   22 ( 2 )   224 - 226   2018.6

Role of Myeloid Lineage Cell Autophagy in Ischemic Brain Injury Reviewed Major achievement

STROKE   49 ( 6 )   1488 - 1495   2018.6( ISSN：0039-2499 )

Nicorandil increased the cerebral blood flow via nitric oxide pathway and ATP-sensitive patassium channel opening in mice Reviewed

Journal of Anesthesia   2018.3( ISSN：0913-8668 )

Delayed-Onset Bilateral Vocal Cord Paralysis After Abdominal Surgery: A Case Report Reviewed

A&A Practice   2017.12

Neuroprotective effects of amiodarone in a mouse model of ischemic stroke Reviewed

BMC Anesthesiology   2017.12( ISSN：1471-2253 )

The effects of Y-27632 on pial microvessels during global brain ischemia and reperfusion in rabbits Reviewed

BMC Anesthesiology   2017.3( ISSN：1471-2253 )

Anesthetic Management of a Child With Jeune Syndrome for Tracheotomy: A Case Report. Reviewed

A&A Case Reports   2017.3

Effects of hyperventilation on cerebral oxygen saturation estimated using near-infrared spectroscopy: A randomised comparison between propofol and sevoflurane anaesthesia. Reviewed

EUROPEAN JOURNAL OF ANAESTHESIOLOGY   2016.12( ISSN：0265-0215 )

アドレナリン不応性アナフィラキシーショックに対しノルアドレナリンが有効であった1症例 Reviewed Major achievement

大宮　啓輔,正宗　大士,池本　剛大,古藤田　眞和,浅野　伸将,松川　隆

日本小児麻酔学会誌   22 ( 1 )   249 - 251   2016.9

Effects of hyperventilation on cerebral oxygen saturation estimated using near-infrared spectroscopy A randomised comparison between propofol and sevoflurane anaesthesia Reviewed Major achievement

European Journal of Anaesthesiology   33   929 - 935   2016.7

The effects of Patent Blue dye on peripheral and cerebral oxyhaemoglobin saturations Reviewed Major achievement

Anaesthesia   70 ( 4 )   429 - 433   2015.4

Direct effects of Rho-kinase inhibitor on pial microvessels in rabbits Reviewed Major achievement

Journal of Anesthesia   29 ( 2 )   186 - 190   2015.4

Optimal doses of sevoflurane and propofol in rabbits Reviewed Major achievement

BMC Research Notes   7   820 P.1 - 820 P.7   2014.11

人工膝関節置換術での大腿神経ブロックの方法と術後鎮痛効果 Reviewed Major achievement

菱山　壮平,石山　忠彦,浅野　伸将,古藤田　眞和,池本　剛大,松川　隆

麻酔   63 ( 8 )   872 - 876   2014.8

非福山型筋ジストロフィー患者に対するアキレス腱延長術の麻酔経験 Reviewed Major achievement

上田　健太,石山　忠彦,古藤田　眞和,浅野　伸将,三井　一葉,松川　隆

臨床麻酔   38 ( 7 )   1069 - 1071   2014.7

Ultrasound-guided out-of-plane obturator nerve block Reviewed Major achievement

Anaesthesia   68 ( 10 )   1074 - 1075   2013.10

Cardiac arrest after spinal anesthesia in a patient with neurally mediated syncope Reviewed Major achievement

Tadahiko ISHIYAMA,Kazuhiro SHIBUYA,Yoshihide　TERADA,Hironobu

Journal of Anesthesia   26   103 - 106   2012.1

Association between sleep duration on the night before surgery and postoperative cognitive function: a prospective cohort study. International conference

Masakazu Kotoda

International Anesthesia Research Society 2021 Annual Meeting and International Science Symposium  2021.5 

Association between sleep duration on the night before surgery and postoperative cognitive function: a prospective cohort study. International conference

Masakazu Kotoda

International Anesthesia Research Society 2021 Annual Meeting and International Science Symposium  2021.5 

Roles of Toll Like Receptor 4 and Myeloid Differentiation Primary Response Protein 88 in the Development of Intracranial Aneurysmal Rupture International conference

American Society of Anesthesiologists Annual Meeting 2018  2018.10 

Amiodarone Exacerbates Brain Injuries after Hypoxic-ischemic Insult in Mice International conference

American Society of Anesthesiologists Annual Meeting 2018  2018.10 

Amiodarone Exacerbates Brain Injuries after Hypoxic-ischemic Insult in Mice International conference

American Society of Anesthesiologists Annual Meeting 2018  2018.10 

Roles of Toll Like Receptor 4 and Myeloid Differentiation Primary Response Protein 88 in the Development of Intracranial Aneurysmal Rupture International conference

American Society of Anesthesiologists Annual Meeting 2018  2018.10 

Neuroprotective effects of neurotropin in a mouse model of hypoxic-ischemic brain injury International conference

American Society of Anesthesiologists Annual Meeting 2018  2018.10 

Safe Stylet Use During Tracheal Intubation: A Mathematical Analysis and In vitro Experimental Study International conference

American Society of Anesthesiologists Annual Meeting 2018  2018.10 

Neuroprotective effects of neurotropin in a mouse model of hypoxic-ischemic brain injury International conference

American Society of Anesthesiologists Annual Meeting 2018  2018.10 

Safe Stylet Use During Tracheal Intubation: A Mathematical Analysis and In vitro Experimental Study International conference

American Society of Anesthesiologists Annual Meeting 2018  2018.10 

Antinociceptive effect of amiodarone in mouse models of pain International conference

International Association for the Study of Pain (IASP) 2018 World Congress on Pain  2018.9 

Antinociceptive effect of amiodarone in mouse models of pain International conference

International Association for the Study of Pain (IASP) 2018 World Congress on Pain  2018.9 

Fogarty カテーテルとエアウェイスコープを用いて分離肺換気を行った膿胸の一症例

日本小児麻酔学会　第23回大会  2017.10 

Fogarty カテーテルとエアウェイスコープを用いて分離肺換気を行った膿胸の一症例

日本小児麻酔学会 第23回大会  2017.10 

乳児VSDの麻酔-山梨大学医学部附属病院- Major achievement

古藤田　眞和

日本心臓血管麻酔学会第21回学術大会  2016.9 

マウス脳血流量に対するニコランジルの作用 Major achievement

古藤田　眞和,菱山　壮平,浅野　伸将,三井　一葉,石山　忠彦,松川　隆

日本心臓血管麻酔学会第21回学術大会  2016.9 

Laryngeal myoclonus:A Case Report Major achievement

2016.9 

A Case of Noradrenaline Effective in Adrenaline Refractory Anaphylactic Shock Major achievement

The 63rd Annual Meeting of the Japanese Society of Anesthesiologists  2016.5 

Neuroprotective effect of amiodarone in mouse model of ischemic stroke International conference Major achievement

IARS 2016Annual Meeting and International Science Symposium  2016.5 

Roles of myeloid cell autophagy in the secondary injury after ischemic stroke. International conference

American Society of Anesthesiologists Annual Meeting 2015  2015.10 

The Effects of lnhaled Nitric Oxide on Pial Microvessels Under Ischemia in Rabbits International conference Major achievement

American Society of Anesthesiologists Annual Meeting 2014  2014.10 

Anesthetic management of congenital clubfoot patients in early infancy Major achievement

2014.9 

大動脈弁閉鎖不全症の手術中、経食道心エコーでバルサルバ洞に解離を発見し術式変更を行った一例 Major achievement

浅野　伸将,石山　忠彦,三井　一葉,古藤田　眞和,中楯　陽介,佐藤　宏明

日本心臓血管麻酔学会第19回学術大会  2014.9 

セボフルラン気化器接合部からの一時的リークが原因と考えられた麻酔回路内酸素濃度低下の 1 例 Major achievement

鈴木　和博,浅野　伸将,古藤田　眞和,上田　健太,小口　健史,松川　隆

日本麻酔科学会関東甲信越/東京支部第54回合同学術集会  2014.8 

The Effects of Vasopressin on Pial Microvessels During Global Brain Iscemia-Reperfusion Period in Rabbits International conference Major achievement

American Society of Anesthesiologists Annual Meeting 2013  2013.10 

Changes of arterial oxygen saturation and cerebral oxygen saturation after the use of patent blue in a patient receiving breast cancer operation Major achievement

2013.5 

麻酔導入直後にアナフィラキシーショックを来たした1症例 Major achievement

上田　健太,渋谷　和広,奥山　克巳,古藤田　眞和,近藤　大資,松川　隆

第45回甲信麻酔談話会  2012.11 

A case report: Retrophryngeal hematoma after Stellate Ganglion Block requiring tracheotomy Major achievement

2012.9 

2 cases of sinus arrest during brain surgery Major achievement

2012.9 

Three cases of stellate ganglion block by lateral approach using a linear probe Major achievement

2012.9 

The Effect of Blood Glucose Levels on the Shivering Threshold in Rabbits(Hypoglycemia Version) Major achievement

2012.9 

日本白ウサギにおけるセボフルラン、プロポフォール単独およびデクスメデトミジン併用での至適投与量の評価 Major achievement

浅野　伸将,石山　忠彦,鈴木　翔,古藤田　眞和,新谷　則之,市川　学,寺田　仁秀,渋谷　和広,松川　隆

第16回日本神経麻酔・集中治療研究会  2012.4 

Jeune症候群の患児に対する気管切開術の麻酔経験 Major achievement

古藤田　眞和,堀本　洋,諏訪　まゆみ,梶田　博史,北村　祐司,藤永　あゆみ,加古　裕美,山口　嘉一,釜田　峰都,田中　英文

日本小児麻酔学会第17回大会  2011.9 

拡張型心筋症合併の心房中隔欠損閉鎖術の麻酔経験 Major achievement

近藤　聡子,奥山　克巳,佐藤　宏明,古藤田　眞和,正宗　大士,松川　隆

日本小児麻酔学会 第16回学術集会  2010.9 

4回目の全身麻酔の終了間際に悪性高熱症の発症が疑われた一例 Major achievement

三井　一葉,池本　剛大,古藤田　眞和,花形　和之,小口　健史,松川　隆

(社)日本麻酔科学会関東甲信越・東京支部 第50回合同学術集会  2010.9 

帝王切開術中に眼球上転を来した一例 Major achievement

丸山恵梨香,古藤田　眞和,飯嶋　哲也,岩下　博宣,木内　理子,寺田仁秀,松川　隆

第42回甲信麻酔談話会  2009.11 

電動式PCAポンプを用いて管理し得た内視鏡的胃粘膜下層剥離術の一症例 Major achievement

飯嶋　哲也,長戸　聡子,熊倉　康友,古藤田　眞和,池本　剛大,川村　淳夫,松川　隆

(社)日本麻酔科学会 関東甲信越・東京支部 第49回合同学術集会  2009.9 

チアノーゼ性心疾患を合併した十二指腸閉鎖症患児の麻酔経験 Major achievement

池本　剛大,奥山　克巳,古藤田　眞和,浅野伸将,正宗　大士,古屋　敦司,松川　隆

日本小児麻酔学会第15回大会  2009.9 

非福山型筋ジストロフィー患者に対するアキレス腱延長術の麻酔経験 Major achievement

古藤田　眞和,市川　ゆき子,奥山　克巳,渋谷　和広,正宗　大士,松川　隆

第41回 甲信麻酔談話会  2008.11