山梨大学研究生(内科学講座第２教室)

2002.10

山梨医科大学研究生(内科学第２)

2001.5

山梨医科大学研修医(内科学第２)

2000.5

Prognostic Value of Novel Natriuretic Peptide Index After Percutaneous Coronary Intervention Reviewed

CIRCULATION JOURNAL   2023.1( ISSN：1346-9843 )

Optimal medical therapy after percutaneous coronary intervention in very elderly patients with coronary artery disease Reviewed

Int J Cardiol Cardiovasc Risk Prev   2022.11

A Propensity Score Matched Analysis of Statin Effects on Major Adverse Cardiac Events after Percutaneous Coronary Intervention in Patients Over 75 Years Old Reviewed

INTERNAL MEDICINE   2022.2( ISSN：0918-2918 )

Stratification analysis of statin effect on major adverse cardiac events after percutaneous coronary intervention in patients on hemodialysis Reviewed

Horikoshi T, Nakamura T, Yoshizaki T, Nakamura J, Makino A, Saito Y, Obata JE, Sawanobori T, Takano H, Umetani K, Watanabe A, Asakawa T, Kugiyama K.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY   2021.10( ISSN：0160-2446 )

Renal tubulointerstitial damage is residuak renal risk factor for adverse cardiac events in patients with myocardial infarction Reviewed

J Cardiol.   2021.4

Echolucency of carotid plaque is useful for selecting high-risk patients with chronic coronary artery disease who benefit from intensive lipid-lowering therapy

J Cardiol.   2021.1

Structural thickening of medial layer in coronary artery with spasm in patients with myocardial infarction

Nakamura T, Horikoshi T, Kugiyama K.

J Am Heart Assoc.   2021.1

Impact of persistent endothelial dysfunction in an infarct-related coronary artery on future major adverse cardiovascular event occurrence in STEMI survivors

Impact of persistent endothelial dysfunction in an infarct-related coronary artery on future major adverse cardiovascular event occurrence in STEMI survivors

Heart Vessels.   2020.11

Improvement in Brachial Endothelial Vasomotor Function and Brachial-Ankle Pulse Wave Velocity Reduces the Residual Risk for Cardiovascular Events after Optimal Medical Treatment in Patients with Coronary Artery Disease

J Atheroscler Thromb   2020.9

Persistent myocardial production of follistatin-like 1 is associated with left ventricular adverse remodeling in patients with myocardial infarction: myocardial production of FSTL1 in AMI patients

J Card Fail.   2020.8

Protein S-glutathionylation stimulate adipogenesis by stabilizing C/EBPβ in 3T3L1 cells

Watanabe Y, Watanabe K, Fujioka D, Nakamura K, Nakamura T, Uematsu M, Bachschmid MM, Matsui R, Kugiyama K.   2020.3

Improvement of endothelial dysfunction is mediated through reduction of remnant lipoprotein after statin therapy in patients with coronary artery disease. Reviewed

Nakamura T, Uematsu M, Yoshizaki T, Kobayashi T, Watanabe Y, Kugiyama K.

J Cardiol   2020.3

Sustained endothelial dysfunction in the infarct-related coronary artery is associated with left ventricular adverse remodeling in survivors of ST-segment elevation myocardial infarction. Reviewed

J Cardiol   2020.3

Relationship of a thinned medial layer to the attenuated contractile response in atherosclerotic coronary arteries. Reviewed

Relationship of a thinned medial layer to the attenuated contractile response in atherosclerotic coronary arteries.   2019.12

Persistent Dysfunction of Coronary Endothelial Vasomotor Responses is Related to Atheroma Plaque Progression in the Infarct-Related Coronary Artery of AMI Survivors. Reviewed

Horikoshi T, Obata JE, Nakamura T, Fujioka D, Watanabe Y, Nakamura K, Watanabe K, Saito Y, Kugiyama K.

J Atheroscler Thromb   2019.12

Remnant Lipoproteins Are Residual Risk Factor for Future Cardiovascular Events in Patients With Stable Coronary Artery Disease and On-Statin Low-Density Lipoprotein Cholesterol Levels <70 mg/dL. Reviewed

Fujihara Y, Nakamura T, Horikoshi T, Obata JE, Fujioka D, Watanabe Y, Watanabe K, Kugiyama K.

Circ J   2019.6

High levels of stromal cell-derived factor-1α predict short-term progression of renal dysfunction in patients with coronary artery disease. Reviewed

Clinical and Experimental Nephrology   2019.3( ISSN：1342-1751 )

Pulmonary Vascular Resistance Is Associated With Brachial-Ankle Pulse-Wave Velocity and Adverse Clinical Outcomes in Patients With Heart Failure With Preserved Ejection Fraction. Reviewed

Nakamura T, Uematsu M, Deyama J, Watanabe Y, Nakamura K, Kobayashi T, Saito Y, Fujioka D, Kawabata KI, Obata JE, Kugiyama K.

JOURNAL OF CARDIAC FAILURE   2019.2( ISSN：1071-9164 )

Human soluble phospholipase A2 receptor is an inhibitor of the integrin-mediated cell migratory response to collagen-I. Reviewed

Watanabe K, Watanabe K, Watanabe Y, Fujioka D, Nakamura T, Nakamura K, Obata JE, Kugiyama K.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY   2018.9( ISSN：0363-6135 )

Effect of coronary artery spasm on long-term outcomes in survivors of acute myocardial infarction. Reviewed

Deyama J, Nakamura T, Saito Y, Obata JE, Fujioka D, Nakamura K, Watanabe K, Kugiyama K.

INTERNATIONAL JOURNAL OF CARDIOLOGY   2018.4( ISSN：0167-5273 )

Angiotensin II receptor blockers suppress the release of stromal cell-derived factor-1α from infarcted myocardium in patients with acute myocardial infarction. Reviewed

Yoshizaki T, Uematsu M, Obata JE, Nakamura T, Fujioka D, Watanabe K, Nakamura K, Kugiyama K.

Journal of Cardiology   2018.4( ISSN：0914-5087 )

Echolucency of the carotid artery is associated with short-term plaque progression and positive remodeling in the culprit coronary artery in AMI survivors.

Futamata M, Matsuoka S, Shimizu T, Yoshizaki T, Obata JE, Nakamura T, Fujioka D, Watanabe Y, Nakamura K, Watanabe K, Kugiyama K.

Journal of Cardiology   2017.11( ISSN：0914-5087 )

Remnant lipoproteinemia predicts cardiovascular events in patients with type 2 diabetes and chronic kidney disease.

Nguyen SV, Nakamura T, Uematsu M, Fujioka D, Watanabe K, Watanabe Y, Obata JE, Nakamura K, Kugiyama K.

Journal of Cardiology   2017.3( ISSN：0914-5087 )

High levels of stromal cell-derived factor-1α predict secondary cardiac events in stable patients with a history of myocardial infarction.

Matsuoka S, Uematsu M, Nakamura T, Shimizu T, Futamata M, Obata JE, Fujioka D, Nakamura K, Yoshizaki T, Kugiyama K.

Journal of Cardiology   2017.1( ISSN：0914-5087 )

High levels of stromal cell-derived factor-1α predict secondary cardiac events in stable patients with a history of myocardial infarction. Reviewed Major achievement

Journal of Cardiology   69 ( 1 )   320 - 325   2017.1( ISSN：0914-5087 )

Myocardial Production of Plasminogen Activator Inhibitor-1 is Associated with Coronary Endothelial and Ventricular Dysfunction after Acute Myocardial Infarction. Reviewed Major achievement

Takuya SHIMIZU,Manabu UEMATSU,Toru YOSHIZAKI,Junei OBATA,Takamitsu NAKAMURA,Daisuke FUJIOKA,Kazuhiro WATANABE,Yosuke WATANABE,Kiyotaka KUGIYAMA

Journal of Atherosclerosis and Thrombosis   23 ( 5 )   557 - 566   2016.5( ISSN：1340-3478 )

Sustained myocardial production of stromal cell-derived factor-1α was associated with left ventricular adverse remodeling in patients with myocardial infarction. Reviewed Major achievement

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY   309 ( 10 )   H1764 - 1771   2015.11( ISSN：0363-6135 )

Assessment of carotid plaque neovascularization using quantitative analysis of contrast-enhanced ultrasound imaging is useful for risk stratification in patients with coronary artery disease. Reviewed Major achievement

Jun NAKAMURA,Takamitsu NAKAMURA,Juntaro DEYAMA,Daisuke FUJIOKA,Kenichi KAWABATA,Kazuhiro WATANABE,Yosuke WATANABE,Kiyotaka KUGIYAMA

INTERNATIONAL JOURNAL OF CARDIOLOGY   195   113 - 119   2015.9( ISSN：0167-5273 )

Echolucent Carotid Plaque is Associated with Future Renal Dysfunction in Patients with Stable Coronary Artery Disease. Reviewed Major achievement

Tetsuji MOCHIDA,Takamitsu NAKAMURA,Kazuto NAKAMURA,Daisuke FUJIOKA,Yukio SAITO,Junei OBATA,Yosuke WATANABE,Kenichi KAWABATA,Kiyotaka KUGIYAMA

Journal of Atherosclerosis and Thrombosis   22 ( 7 )   685 - 696   2015.6( ISSN：1340-3478 )

C-type lectin-like domain and fibronectin-like type II domain of phospholipase A2 receptor 1 modulate binding and migratory responses to collagen. Reviewed Major achievement

Souichiro TAKAHASHI,Kazuhiro WATANABE,Yosuke WATANABE,Daisuke FUJIOKA,Takamitsu NAKAMURA,Kazuto NAKAMURA,Junei OBATA,Kiyotaka KUGIYAMA

FEBS letters   589 ( 7 )   829 - 835   2015.3

The Expression of Groups IIE and V Phospholipase A2 is Associated with an Increased Expression of Osteogenic Molecules in Human Calcified Aortic Valves. Reviewed Major achievement

Kouji SUZUKI,Souichiro TAKAHASHI,Kazuhiro WATANABE,Daisuke FUJIOKA,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Ryohei KATOH,Masahiko MATSUMOTO,Kiyotaka KUGIYAMA

Journal of Atherosclerosis and Thrombosis   21 ( 12 )   1308 - 1325   2014.12

High Remnant Lipoprotein Predicts Recurrent Cardiovascular Events on Statin Treatment After Acute Coronary Syndrome. Reviewed Major achievement

Si Van Nguyen,Takamitsu NAKAMURA,Kiyotaka KUGIYAMA

Circulation Journal   78 ( 10 )   2492 - 2500   2014.9

The combined assessment of flow-mediated dilation of the brachial artery and brachial-ankle pulse wave velocity improves the prediction of future coronary events in patients with chronic coronary artery disease. Reviewed Major achievement

Wataru SUGAMATA,Takamitsu NAKAMURA,Manabu UEMATSU,Yoshinobu KITTA,Daisuke FUJIOKA,Yukio SAITO,Kenichi KAWABATA,Junei OBATA,Yosuke WATANABE,Kazuhiro WATANABE,Kiyotaka KUGIYAMA

Journal of Cardiology   64 ( 3 )   179 - 184   2014.9

Lack of phospholipase A2 receptor increases susceptibility to cardiac rupture after myocardial infarction. Reviewed Major achievement

Hideto MISHINA,Kazuhiro WATANABE,Syun TAMARU,Yosuke WATANABE,Daisuke FUJIOKA,Souichiro TAKAHASHI,Kouji SUZUKI,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Yasunori YOKOTA,Osamu INOUE,Makoto MURAKAMI,Hanasaki KOUJI,Kiyotaka KUGIYAMA

Circulation Research   114 ( 3 )   493 - 504   2014.1

Echolucency of Carotid Plaque Is Useful for Assessment of Residual Cardiovascular Risk in Patients With Chronic Coronary Artery Disease Who Achieve LDL-C Goals on Statin Therapy. Reviewed Major achievement

Manabu UEMATSU,Takamitsu NAKAMURA,Wataru SUGAMATA,Yoshinobu KITTA,Daisuke FUJIOKA,Yukio SAITO,Kenichi KAWABATA,Junei OBATA,Yosuke WATANABE,Kazuhiro WATANABE,Kiyotaka KUGIYAMA

Circulation journal   78 ( 1 )   151 - 158   2014.1

Optical coherence tomography and histopathological assessment of delayed arterial healing after drug-eluting stent implant in a pig coronary model. Reviewed Major achievement

Matsumoto D,Shinke T,Takamitsu NAKAMURA,Shite J,Li J,Hou D,Chronos N

International Journal of Cardiology   170 ( 2 )   152 - 159   2013.12

In-stent restenosis is inhibited in a bare metal stent implanted distal to a sirolimus-eluting stent to treat a long de novo coronary lesion with small distal vessel diameter. Reviewed Major achievement

Junei OBATA,Takamitsu NAKAMURA,Yoshinobu KITTA,Yukio SAITO,Keita SANO,Daisuke FUJIOKA,Kenichi KAWABATA,Kiyotaka KUGIYAMA

Catheterization and Cardiovascular Interventions   82 ( 6 )   E777 - 787   2013.11

Phospholipase A2 expression in coronary thrombus is increased in patients with recurrent cardiac events after acute myocardial infarction. Reviewed Major achievement

Souichiro TAKAHASHI,Kouji SUZUKI,Yosuke WATANABE,Kazuhiro WATANABE,Daisuke FUJIOKA,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Hideto MISHINA,Kiyotaka KUGIYAMA

International journal of cardiology.   168 ( 4 )   4214 - 4221   2013.10

Deficiency of phospholipase A2 receptor exacerbates ovalbumin-induced lung inflammation. Reviewed Major achievement

Syun TAMARU,Hideto MISHINA,Yosuke WATANABE,Kazuhiro WATANABE,Daisuke FUJIOKA,Souichiro TAKAHASHI,Kouji SUZUKI,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Yasunori YOKOTA,Makoto MURAKAMI,Kohji HANASAKI,Kiyotaka KUGIYAMA

Jounal of immunology   191 ( 3 )   1021 - 1028   2013.8

Ultrasound assessment of brachial endothelial vasomotor function in addition to carotid plaque echolucency for predicting cardiovascular events in patients with coronary artery disease. Reviewed Major achievement

Takamitsu NAKAMURA,Yoshinobu KITTA,Manabu UEMATSU,Wataru SUGAMATA,Mitsumasa HIRANO,Daisuke FUJIOKA,Keita SANO,Yukio SAITO,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

International journal of cardiology.   167 ( 2 )   555 - 560   2013.7

Contrast-Enhanced Ultrasound Imaging of Carotid Plaque Neovascularization Is Useful for Identifying High-Risk Patients With Coronary Artery Disease. Reviewed Major achievement

Juntaro DEYAMA,Takamitsu NAKAMURA,Isao TAKISHIMA,Daisuke FUJIOKA,Kenichi KAWABATA,Junei OBATA,Kazuhiro WATANABE,Yousuke WATANABE,Yukio SAITO,Hideto MISHINA,Kiyotaka KUGIYAMA

Circulation journal.   77 ( 6 )   1499 - 1507   2013.5

Chronic depletion of glutathione exacerbates ventricular remodelling and dysfunction in the pressure-overloaded heart. Reviewed Major achievement

Yosuke WATANABE,Kazuhiro WATANABE,Tsuyoshi KOBAYASHI,Yukio SAITO,Daisuke FUJIOKA,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Hideto MISHINA,Kiyotaka KUGIYAMA

Cardiovascular research   97 ( 2 )   282 - 292   2013.2

Usefulness of a collateral channel dilator for antegrade treatment of chronic total occlusion of a coronary artery. Reviewed Major achievement

Junei OBATA,Takamitsu NAKAMURA,Yoshinobu KITTA,Yukio SAITO,Keita SANO,Daisuke FUJIOKA,Kenichi KAWABATA,Kiyotaka KUGIYAMA

Journal of interventional cardiology   25 ( 6 )   533 - 539   2012.12

Vasomotor function and molecular responses following drug-eluting stent in a porcine coronary model. Reviewed Major achievement

Takamitsu NAKAMURA,Jing C,Xinhua Y,Li J,King SB 3rd,Chronos N,McDonald JF,Hou D

International journal of cardiology.   160 ( 3 )   210 - 212   2012.10

Vasomotor function and molecular responses following drug-eluting stent in a porcine coronary model. Reviewed Major achievement

Nakamura T,Jing C,Xinhua Y,Li J,Chen JP,King SB 3rd,Chronos N,McDonald JF,Hou D.

Int J Cardiol.   160 ( 3 )   210 - 212   2012.10

Vasomotor function and re-endothelialisation after implantation of biodegradable abluminal polymer coated paclitaxel-eluting stents in rabbit iliac arteries: a time-course study. Reviewed Major achievement

Takamitsu NAKAMURA,Winsor-Hines D,Yin X,Sushkova N,Chen JP,King SB 3rd,Chronos N,Eppihimer M,Huibregtse B,Dawkins KD,Hou D

EuroIntervention.   8 ( 4 )   493 - 500   2012.8

Vasomotor function and re-endothelialisation after implantation of biodegradable abluminal polymer coated paclitaxel-eluting stents in rabbit iliac arteries: a time-course study. Reviewed Major achievement

EuroIntervention.   8   493 - 500   2012.8

Predictive value of serial assessment of endothelial function in chronic heart failure. Reviewed Major achievement

Isao TAKISHIMA,Takamitsu NAKAMURA,Mitsumasa HIRANO,Yoshinobu KITTA,Tsuyoshi KOBAYASHI,Daisuke FUJIOKA,Yukio SAITO,Kazuhiro WATANABE,Yosuke WATANABE,Hideto MISHINA,Junei OBATA,Kenichi KAWABATA,Syun TAMARU,Kiyotaka KUGIYAMA

International journal of cardiology   158 ( 3 )   417 - 422   2012.7

A comparison of the efficacy of combined ezetimibe and statin therapy with doubling of statin dose in patients with remnant lipoproteinemia on previous statin therapy. Reviewed Major achievement

Takamitsu NAKAMURA,Mitsumasa HIRANO,Yoshinobu KITTA,Daisuke FUJIOKA,Yukio SAITO,Kenichi KAWABATA,Junei OBATA,Yosuke WATANABE,Kazuhiro

Journal of cardiology   60 ( 1 )   12 - 17   2012.7

メタボリックシンドロームにおけるResidual Major achievement

33 ( 6 )   856 - 860   2012.6

Early Improvement in Carotid Plaque Echogenicity by Acarbose in Patients With Acute Coronary Syndromes. Reviewed Major achievement

Mitsumasa HIRANO,Takamitsu NAKAMURA,Junei OBATA,Daisuke FUJIOKA,Yukio SAITO,Kenichi KAWABATA,Kazuhiro WATANABE,Yosuke WATANABE,Kiyotaka KUGIYAMA

Circulation Journal   76 ( 6 )   1452 - 1460   2012.6

Disruption of group IVA cytosolic phospholipase A2 attenuates myocardial ischemia-reperfusion injury partly through inhibition of TNF-α-mediated pathway. Reviewed Major achievement

Yukio SAITO,Kazuhiro WATANABE,Daisuke FUJIOKA,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Yosuke WATANABE,Hideto MISHINA,Syun TAMARU,Yoshinobu KITTA,Shimizu T,Kiyotaka KUGIYAMA

American journal of physiology. Heart and circulatory physiology   302 ( 10 )   H2018 - 2030   2012.5

Group X secretory PLA2 in neutrophils plays a pathogenic role in abdominal aortic aneurysms in mice. Reviewed Major achievement

Kazuhiro WATANABE,Daisuke FUJIOKA,Yukio SAITO,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Yosuke WATANABE,Hideto MISHINA,Syun TAMARU,Hanasaki Kouji,Kiyotaka KUGIYAMA

American journal of physiology. Heart and circulatory physiology   302 ( 1 )   95 - 104   2012.1

Vasomotor function after paclitaxel-coated balloon post-dilation in porcine coronary stent model. Reviewed Major achievement

Takamitsu NAKAMURA,Brott BC,Brants I,Panchal D,Li J,Chen JP,King SB 3rd,Chronos N,Hou D

JACC Cardiovasc Interv.   4 ( 2 )   247 - 255   2011.9

Predictive value of remnant lipoprotein for cardiovascular events in patients with coronary artery disease after achievement of LDL-cholesterol goals. Reviewed Major achievement

Takamitsu NAKAMURA,Junei OBATA,Mistumasa HIRANO,Yoshinobu KITTA,Daisuke FUJIOKA,Yukio SAITO,Kenichi KAWABATA,Kazuhiro WATANABE,Yosuke WATANABE,Hideto MISHINA,Kiyotaka KUGIYAMA

Atherosclerosis   218 ( 1 )   163 - 167   2011.9

Group V secretory phospholipase A2 plays a pathogenic role in myocardial ischaemia-reperfusion injury. Reviewed Major achievement

Toshiaki YANO,Daisuke FUJIOKA,Yukio SAITO,Tsuyoshi KOBAYASHI,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Kazuhiro WATANABE,Yosuke WATANABE,Hideto MISHINA,Syun TAMARU,Kiyotaka KUGIYAMA

CARDIOVASCULAR RESEARCH   90 ( 2 )   335 - 343   2011.5

Short-term progression of maximum intima-media thickness of carotid plaque is associated with future coronary events in patients with coronary artery disease. Reviewed Major achievement

Mitsumasa HIRANO,Takamitsu NAKAMURA,Yoshinobu KITTA,Isao TAKISHIMA,Juntaro DEYAMA,Tsuyoshi KOBAYASHI,Daisuke FUJIOKA,Yukio SAITO,Kazuhiro WATANABE,Yosuke WATANABE,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

Atherosclerosis   215 ( 2 )   507 - 512   2011.4

Endothelial vasomotor dysfunction in the brachial artery predicts the short-term development of early stage renal dysfunction in patients with coronary artery disease. Reviewed Major achievement

Takamitsu NAKAMURA,Junei OBATA,Mitsumasa HIRANO,Yoshinobu KITTA,Keita SANO,Tsuyoshi KOBAYASHI,Daisuke FUJIOKA,Yukio SAITO,Toshiaki YANO,Kenichi KAWABATA,Kazuhiro WATANABE,Yosuke WATANABE,Hideto MISHINA,Kiyotaka KUGIYAMA

International journal of cardiology   148 ( 2 )   183 - 188   2011.4

Vasomotor Function Following Paclitaxel-coated balloon post-dilatation in porcine coronary stent model. JACC Cardiovasc Interv. Reviewed Major achievement

Nakamura T,Brigitta BC,Brants I,Panchal D,Li J,Chen JP,King SB 3rd,Chronos N,Hou D.

J Am Coll Cardiol Intv.   4   247 - 255   2011.2

High plasma levels of macrophage migration inhibitory factor are associated with adverse long-term outcome in patients with stable coronary artery disease and impaired glucose tolerance or type 2 diabetes mellitus. Reviewed Major achievement

Aritaka MAKINO,Takamitsu NAKAMURA,Mitsumasa HIRANO,Yoshinobu KITTA,Keita SANO,Tsuyoshi KOBAYASHI,Daisuke FUJIOKA,Yukio SAITO,Kazuhiro WATANABE,Yosuke WATANABE,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

Atherosclerosis   213 ( 2 )   573 - 578   2010.12

Inhibition of secretory phospholipase A2 activity attenuates acute cardiogenic pulmonary edema induced by isoproterenol infusion in mice after myocardial infarction. Reviewed Major achievement

Kenichi KAWABATA,Daisuke FUJIOKA,Tsuyoshi KOBAYASHI,Yukio SAITO,Junei OBATA,Takamitsu NAKAMURA,Toshiaki YANO,Kazuhiro WATANABE,Yosuke WATANABE,Hideto MISHINA,Kiyotaka KUGIYAMA

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY   56 ( 4 )   369 - 378   2010.10

Comparative study of bezafibrate and pravastatin in patients with coronary artery disease and high levels of remnant lipoprotein. Reviewed Major achievement

Keita SANO,Takamitsu NAKAMURA,Mitsumasa HIRANO,Yoshinobu KITTA,Tsuyoshi KOBAYASHI,Daisuke FUJIOKA,Yukio SAITO,Toshiaki YANO,Kazuhiro WATANABE,Yosuke WATANABE,Hideto MISHINA,Junei OBATA,Kenichi KAWABATA,Kiyotaka KUGIYAMA

CIRCULATION JOURNAL   74 ( 8 )   1644 - 1650   2010.8

The role of intravascular ultrasound to guide drug-eluting stents implantation. Reviewed Major achievement

Takamitsu NAKAMURA,Chen JP,Panchal D,Nguyen T,King SB 3rd,Chronos N,Hou D

Cardiovascular & hematological agents in medicinal chemistry   8 ( 1 )   22 - 28   2010.1

Measurement of the platelet retention rate in a column of collagen-coated beads is useful for the assessment of efficacy of antiplatelet therapy. Reviewed Major achievement

Akira MENDE,Junei OBATA,Keita SANO,Mitsumasa HIRANO,Yoshinobu KITTA,Yasushi KODAMA,Takamitsu NAKAMURA,Kenichi KAWABATA,Yukio SAITO,Daisuke FUJIOKA,Tsuyoshi KOBAYASHI,Kaneo SATOH,Yukio OZAKI,Toshiaki YANO,Kiyotaka KUGIYAMA

Thrombosis Research   123 ( 6 )   856 - 861   2009.4

Rapid improvement of carotid plaque echogenicity within 1 month of pioglitazone treatment in patients with acute coronary syndrome. Reviewed Major achievement

Mitsumasa HIRANO,Takamitsu NAKAMURA,Yoshinobu KITTA,Toshiaki YANO,Tsuyoshi KOBAYASHI,Keita SANO,Daisuke FUJIOKA,Yukio SAITO,Yasushi KODAMA,Kenichi KAWABATA,Kazuto NAKAMURA,Kiyotaka KUGIYAMA

Atherosclerosis   203 ( 2 )   483 - 488   2009.4

Adiponectin is released from the heart in patients with heart failure. Reviewed Major achievement

Hajime TAKANO,Junei OBATA,Yasushi KODAMA,Yoshinobu KITTA,Takamitsu NAKAMURA,Akira MENDE,Kenichi KAWABATA,Yukio SAITO,Daisuke FUJIOKA,Tsuyoshi KOBAYASHI,Toshiaki YANO,Keita SANO,Kiyotaka KUGIYAMA

International Journal of Cardiology   132 ( 2 )   221 - 226   2009.1

Persistent impairment of endothelial vasomotor function has a negative impact on outcome in patients with coronary artery disease. Reviewed Major achievement

Yoshinobu KITTA,Junei OBATA,Takamitsu NAKAMURA,Mitsumasa HIRANO,Yasushi KODAMA,Daisuke FUJIOKA,Yukio SAITO,Kenichi KAWABATA,Keita SANO,Tsuyoshi KOBAYASHI,Toshiaki YANO,Kazuto NAKAMURA,Kiyotaka KUGIYAMA

Journal of the American College of Cardiology   53 ( 4 )   323 - 330   2009.1

High serum levels of remnant lipoproteins predict ischemic stroke in patients with metabolic syndrome and mild carotid atherosclerosis. Reviewed Major achievement

Takamitsu NAKAMURA,Junei OBATA,Hajime TAKANO,Kenichi KAWABATA,Keita SANO,Tsuyoshi KOBAYASHI,Daisuke FUJIOKA,Yukio SAITO,Toshiaki YANO,Kiyotaka KUGIYAMA

Atherosclerosis   202 ( 1 )   234 - 240   2009.1

Low adiponectin levels predict late in-stent restenosis after bare metal stenting in native coronary arteries. Reviewed Major achievement

Yoshinobu KITTA,Hajime TAKANO,Takamitsu NAKAMURA,Yasushi KODAMA,Ken UMETANI,Daisuke FUJIOKA,Yukio SAITO,Kenichi KAWABATA,Junei OBATA,Akira MENDE,Tsuyoshi KOBAYASHI,Kiyotaka KUGIYAMA

International Journal of Cardiology   131 ( 1 )   78 - 82   2008.12

Reduction in myocardial ischemia/reperfusion injury in group X secretory phospholipase A2-deficient mice. Reviewed Major achievement

Daisuke FUJIOKA,Yukio SAITO,Tsuyoshi KOBAYASHI,Toshiaki YANO,Hideo TEZUKA,Yoshikazu ISHIMOTO,Noriko SUZUKI,Y YOKOTA,Takamitsu NAKAMURA,Daisuke FUJIOKA,Masaki KANAZAWA,Kenichi KAWABATA,Kohji HANASAKI,Kiyotaka KUGIYAMA

Circulation   117 ( 23 )   2977 - 2985   2008.6

Statin reverses reduction of adiponectin receptor expression in infarcted heart and in TNF-{alpha}-treated cardiomyocytes in association with improved glucose uptake. Reviewed Major achievement

Yukio SAITO,Daisuke FUJIOKA,Kenichi KAWABATA,Tsuyoshi KOBAYASHI,Toshiaki YANO,Takamitsu NAKAMURA,Yasushi KODAMA,Hajime TAKANO,Yoshinobu KITTA,Junei OBATA,Kiyotaka KUGIYAMA

American journal of physiology Heart and circulatory physiology   293   H3490 - H3497   2007.12

Sirolimus-eluting stent implantation aggravates endothelial vasomotor dysfunction in the infarct-related coronary artery in patients with acute myocardial infarction. Reviewed Major achievement

Junei OBATA,Yoshinobu KITTA,Hajime TAKANO,Yasushi KODAMA,Takamitsu NAKAMURA,Akira MENDE,Kenichi KAWABATA,Yukio SAITO,Daisuke FUJIOKA,Tsuyoshi KOBAYASHI,Toshiaki YANO,Kiyotaka KUGIYAMA

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   50 ( 14 )   1305 - 1309   2007.10

Increase in circulating levels of adiponectin after treatment with attain and fibrate in patients with coronary artery disease and hyperlipidemia. Reviewed Major achievement

Takamitsu NAKAMURA,Yasushi KODAMA,Hajime TAKANO,Ken UMETANI,Daisuke FUJIOKA,Yukio SAITO,Kenichi KAWABATA,Junei OBATA,Yoshinobu KITTA,Kiyotaka KUGIYAMA

ATHEROSCLEROSIS   193 ( 2 )   449 - 451   2007.8

Relation between transcardiac gradient of VEGF and coronary flow response in humans. Reviewed Major achievement

Akira MENDE,Hajime TAKANO,Yasushi KODAMA,Takamitsu NAKAMURA,Ken UMETANI,Daisuke FUJIOKA,Yukio SAITO,Tsuyoshi KOBAYASHI,Kenichi KAWABATA,Junei OBATA,Yoshinobu KITTA,Kiyotaka KUGIYAMA

INTERNATIONAL JOURNAL OF CARDIOLOGY   119 ( 2 )   156 - 162   2007.7

Association of Low Serum Levels of Apolipoprotein A-I With Adverse Outcomes in Patients With Nonischemic Heart Failure. Reviewed Major achievement

Masahiko IWAOKA,Junei OBATA,Makoto ABE,Takamitsu NAKAMURA,Yoshinobu KITTA,Yasushi KODAMA,Kenichi KAWABATA,Hajime TAKANO,Daisuke FUJIOKA,Yukio SAITO,Tsuyoshi KOBAYASHI,Hideyuki HASEBE,Kiyotaka KUGIYAMA

JOURNAL OF CARDIAC FAILURE   13 ( 4 )   247 - 253   2007.5

Association of High Levels of Plasma Free Dopamine With Future Coronary Events in Patients With Coronary Artery Disease. Reviewed Major achievement

Makoto ABE,Masahiko IWAOKA,Takamitsu NAKAMURA,Yoshinobu KITTA,Hajime TAKANO,Yasushi KODAMA,Kenichi KAWABATA,Junei OBATA,Akira MENDE,Tsuyoshi KOBAYASHI,Daisuke FUJIOKA,Yukio SAITO,Hideyuki HASEBE,Kiyotaka KUGIYAMA

CIRCULATION JOURNAL   71 ( 5 )   688 - 692   2007.5

シリーズ危険因子「高脂血症:RLP-C」 Major achievement

中村　貴光,久木山　清貴

動脈硬化予防   6 ( 1 )   92 - 95   2007.4

High Prevalence of Paroxysmal Atrial Fibrillation and / or Atrial Flutter in Metabolic Syndrome. Reviewed Major achievement

Ken UMETANI,Yasushi KODAMA,Takamitsu NAKAMURA,Akira MENDE,Yoshinobu KITTA,Kenichi KAWABATA,Junei OBATA,Hajime TAKANO,Kiyotaka KUGIYAMA

CIRCULATION JOURNAL   71 ( 2 )   252 - 255   2007.2

Transcardiac adiponectin gradient is independently related to endothelial vasomotor function in large and resistance coronary arteries in humans. Reviewed Major achievement

Hajime TAKANO,Yasushi KODAMA,Yoshinobu KITTA,Takamitsu NAKAMURA,Junei OBATA,Akira MENDE,Kenichi KAWABATA,Yukio SAITO,Daisuke FUJIOKA,Tsuyoshi KOBAYASHI,Hideyuki HASEBE,Kiyotaka KUGIYAMA

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY   291   H2641 - H2646   2006.12

Atorvastatin increases plasma soluble Fms-like tyrosine kinase-1 and decreases vascular endothelial growth factor and placental growth factor in association with improvement of ventricular function in acute myocardial infarction. Reviewed Major achievement

Yasushi KODAMA,Yoshinobu KITTA,Takamitsu NAKAMURA,Hajime TAKANO,Ken UMETANI,Daisuke FUJIOKA,Yukio SAITO,Kenichi KAWABATA,Junei OBATA,Akira MENDE,Tsuyoshi KOBAYASHI,Kiyotaka KUGIYAMA

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   48 ( 1 )   43 - 50   2006.7

Triglycerides and remnant particles as risk factors for coronary artery disease. Reviewed Major achievement

Takamitsu NAKAMURA,Kiyotaka KUGIYAMA

Current atherosclerosis reports   8 ( 2 )   107 - 110   2006.3

Role of adiponectin receptors in endothelin-induced cellular hypertrophy in cultured cardiomyocytes and their expression in infarcted heart. Reviewed Major achievement

Daisuke FUJIOKA,Kenichi KAWABATA,Yukio SAITO,Tsuyoshi KOBAYASHI,Takamitsu NAKAMURA,Yasushi KODAMA,Hajime TAKANO,Junei OBATA,Yoshinobu KITTA,Ken UMETANI,Kiyotaka KUGIYAMA

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY   290   H2409 - H2416   2006.1

Endothelial Vasomotor Dysfunction in the Brachial Artery Is Associated With Late In-Stent Coronary Restenosis. Reviewed Major achievement

Yoshinobu KITTA,Takamitsu NAKAMURA,Yasushi KODAMA,Hajime TAKANO,Ken UMETANI,Daisuke FUJIOKA,Yukio SAITO,Kenichi KAWABATA,Junei OBATA,Yoshihide ICHIGI,Akira MENDE,Kiyotaka KUGIYAMA

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   46 ( 4 )   648 - 655   2005.8

Remnant lipoproteinemia is a risk factor for endothelial vasomotor dysfunction and coronary artery disease in metabolic syndrome. Reviewed Major achievement

Takamitsu NAKAMURA,Hajime TAKANO,Ken UMETANI,Kenichi KAWABATA,Junei OBATA,Yoshinobu KITTA,Yasushi KODAMA,Akira MENDE,Yoshihide ICHIGI,Daisuke FUJIOKA,Yukio SAITO,Kiyotaka KUGIYAMA

ATHEROSCLEROSIS   181 ( 2 )   321 - 327   2005.8

メタボリックシンドロームと動脈硬化形成の機序 Major achievement

中村貴光,久木山清貴

医学と薬学   54 ( 1 )   13 - 18   2005.7

Increased Ambulatory Pulse Pressure Is a Strong Risk Factor for Coronary Endothelial Vasomotor Dysfunction. Reviewed Major achievement

Yoshihide ICHIGI,Hajime TAKANO,Ken UMETANI,Kenichi KAWABATA,Junei OBATA,Yoshinobu KITTA,Yasushi KODAMA,Akira MENDE,Takamitsu NAKAMURA,Daisuke FUJIOKA,Yukio SAITO,Kiyotaka KUGIYAMA

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   45 ( 9 )   1461 - 1466   2005.5

高レムナント血症 ― 高脂血症における位置づけ Major achievement

中村　貴光,久木山　清貴

Mebio   22 ( 2 )   90 - 93   2005.2

心血管病リスクとしてのメタボリックシンドローム Major achievement

中村貴光,久木山清貴

内分泌　糖尿病科   19 ( 5 )   530 - 536   2004.11

Correlation of Plasma Concentration of B-Type Natriuretic Peptide With Infarct Size Quantified by Tomographic Thallium-201 Myocardial Scintigraphy in Asymptomatic Patients With Previous Myocardial Infarction. Reviewed Major achievement

Kazuya NAKAGAWA,Ken UMETANI,Daisuke FUJIOKA,Keita SANO,Takamitsu NAKAMURA,Yasushi KODAMA,Yoshinobu KITTA,Yoshihide ICHIGI,Kenichi KAWABATA,Junei OBATA,Hajime TAKANO,Yoshito INOBE,Kiyotaka KUGIYAMA

CIRCULATION JOURNAL   923 - 927   2004.10

Therapeutic angiogenesis by autologous transplantation of bone-marrow cells in a patient with progressive limb ischemia due to arteriosclerosis obliterans. Reviewed Major achievement

Hideyuki HASEBE,Mitsuru OSADA,Yasushi KODAMA,Daisuke FUJIOKA,Keita SANO,Takamitsu NAKAMURA,Toru MITSUMORI,Kazuto NAKAMURA,Yoshinobu KITTA,Yoshihide ICHIGI,Junei OBATA,Kenichi KAWABATA,Mitsuaki YANAGI,Souichi SANO,Hajime TAKANO,Ken UMETANI,Kiyotaka KUGIYAMA

J Cardiol.   43 ( 4 )   179 - 83   2004.4

脂質代謝異常におけるフィブラートの可能性を探る

先端医学社  2005.1 

NSEが抜去困難となった前下行枝対角枝分岐部病変の一例 Major achievement

齊藤　幸生,小林　剛,堀越　健生,二俣　美香,松岡　聡志,清水　琢也,出山　順太郎,植松　学,藤岡　大佑,中村　貴光,中村　和人,川端　健一,尾畑　純栄,久木山　清貴

第48回日本心血管インターベンション治療学会 関東甲信越地方会  2016.5 

Contrast-Enhanced Carotid Plaque for Detection of Myocardial Damage Risk after PCI in ST-segment Elevation Myocardial Infarction Major achievement

Juntaro DEYAMA,Takamitsu NAKAMURA,Jun NAKAMURA,Takeo HORIKOSHI,Mika FUTAMATA,Satoshi MATSUOKA,Takuya SHIMIZU,Manabu UEMATSU,Tsuyoshi KOBAYASHI,Daisuke FUJIOKA,Yukio SAITO,Kazuto NAKAMURA,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

The 80th Annual Scientific Meeting of the Japanese Circulation Society  2016.3 

Myocardial Production of Plasminogen Activator Inhibitor-1 was Associated with Coronary Endothelial and Ventricular Dysfunction after Acute Myocardial Infarction Major achievement

Takuya SHIMIZU,Manabu UEMATSU,Toru YOSHIZAKI,Junei OBATA,Takamitsu NAKAMURA,Yukio SAITO,Kiyotaka KUGIYAMA

The 80th Annual Scientific Meeting of the Japanese Circulation Society  2016.3 

Contrast-Enhanced Carotid Plaque for Detection of Myocardial Damage Risks After PCI in ST-segment Elevation Myocardial Infarction. Major achievement

Juntaro DEYAMA,Takamitsu NAKAMURA,Jun NAKAMURA,Takeo HORIKOSHI,Mika FUTAMATA,Satoshi MATSUOKA,Takuya SHIMIZU,Manabu UEMATSU,Daisuke FUJIOKA,Yukio SAITO,Kazuto NAKAMURA,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2015  2015.11 

Production of Plasminogen Activator Inhibitor-1 in Infarcted Lesion was Associated With Coronary Endothelial Vasomotor Dysfunction and Progressive Dysfunction of Left Ventricle in Patients With Acute Myocardial Infarction. Major achievement

Takuya SHIMIZU,Manabu UEMATSU,Toru YOSHIZAKI,Junei OBATA,Takamitsu NAKAMURA,Yukio SAITO,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2015  2015.11 

スタチン治療後LDL-C管理目標値を達した陳旧性心筋梗塞の患者で、頸動脈プラーク輝度の測定は心血管病の残余リスクの評価に有用である Major achievement

植松　学,中村　貴光,齊藤　幸生,中村　和人,尾畑　純栄,久木山　清貴

第63回日本心臓病学会学術集会  2015.9 

Echolucent carotid plaque is useful for assessment of residual risk in patients with history of myocardial infarction on statin therapy Major achievement

Manabu UEMATSU,Takamitsu NAKAMURA,Tetsuji MOCHIDA,Jun NAKAMURA,Daisuke FUJIOKA,Yukio SAITO,Kazuto NAKAMURA,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

ESC Congress 2015  2015.8 

Assessment of Carotid Plaque Neovascularization Using Quantitative Analysis of Contrast-enhanced Ultrasound Imaging is Useful for Risk Stratification in Patients with Coronary Artery Disease Major achievement

Jun NAKAMURA,Takamitsu NAKAMURA,Juntaro DEYAMA,Mika FUTAMATA,Tetsuji MOCHIDA,Wataru SUGAMATA,Manabu UEMATSU,Yousuke WATANABE,Kazuhiro WATANABE,Daisuke FUJIOKA,Yukio SAITO,Kazuto NAKAMURA,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2014  2014.11 

Expression of Phospholipase A2 Groups IIE and V was Associated with the Development of Calcification in Human Aortic Valves. Major achievement

Kouji SUZUKI,Souichiro TAKAHASHI,Syun TAMARU,Hideto MISHINA,Kazuhiro WATANABE,Daisuke FUJIOKA,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Ryohei KATOH,Kiyotaka KUGIYAMA

The 78th Annual Scientific Meeting of the Japanese Circulation Society  2014.3 

Mice Lacking Phospholipase A2 Receptor are Susceptible to Cardiac Rupture After Myocardial Infarction through the Impaired Healing of the Infarct Region due to Myofibroblasts Dysfunction. Major achievement

Hideto MISHINA,Syun TAMARU,Kazuhiro WATANABE,Daisuke FUJIOKA,Souichiro TAKAHASHI,Kouji SUZUKI,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Yasunori YOKOTA,Kohji HANASAKI,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2013  2013.11 

Deficiency of Phospholipase A2 Receptor Exacerbates Airway Inflammation and Pulmonary Vessel Remodeling After Ovalbumin Treatment Through Impaired Clearance of Secretory Phospholipase A2. Major achievement

Syun TAMARU,Hideto MISHINA,Yosuke WATANABE,Kazuhiro WATANABE,Daisuke FUJIOKA,Souichiro TAKAHASHI,Kouji SUZUKI,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Yasunori YOKOTA,Kohji HANASAKI,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2013  2013.11 

Contrast-Enhanced Ultrasound Overlay Imaging of Carotid Plaque Neovascularization is Useful for Identifying Risk for Acute Coronary Syndrome. Major achievement

Juntaro DEYAMA,Takamitsu NAKAMURA,Jun NAKAMURA,Ｉsao TAKISHIMA,Mika FUTAMATA,Tetsuji MOCHIDA,Manabu UEMATSU,Wataru SUGAMATA,Daisuke FUJIOKA,Yukio SAITO,Kazuto NAKAMURA,Yoshinobu KITTA,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2013  2013.11 

Expression of Phospholipase A2 Groups ⅡE and Ⅴ was Associated With the Development of Calcification and the Upregulated Expression of Osteogenic Molecules in Human Aortic Valves. Major achievement

Kouji SUZUKI,Souichiro TAKAHASHI,Syun TAMARU,Hideto MISHINA,Kazuhiro WATANABE,Daisuke FUJIOKA,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Ryohei KATOH,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2013  2013.11 

Groups ⅡA,ⅣA and Ⅴ Phospholipase A2 in Coronary Thrombus Are Associated With Recurrent Cardiac Events and Development of Atherosclerosis in the Culprit Coronary Artery After Acute Myocardial Infarction. Major achievement

Souichiro TAKAHASHI,Kouji SUZUKI,Syun TAMARU,Yosuke WATANABE,Hideto MISHINA,Kazuhiro WATANABE,Daisuke FUJIOKA,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2013  2013.11 

Contrast-Enhanced Ultrasound Imaging of Carotid Plaque Neovascularization is Useful for Identification of High-Risk Patients for Atherosclerotic Cardiovascular Diseases. Major achievement

Juntaro DEYAMA,Isao TAMISHIMA,Takamitsu NAKAMURA,Manabu UEMATSU,Wataru SUGAMATA,Daisuke FUJIOKA,Keita SANO,Yukio SAITO,Yoshinobu KITTA,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

The 77th Annual Scientific Meeting of the Japanase Circulation Society  2013.3 

Insulin Resistance after Reducing Therapy for Atherosclerotic Risk Factors Negatively Affects Long-term Outcome in Non-diabetic Patients with Coronary Artery Disease. Major achievement

Yoshinobu KITTA,Junei OBATA,Kenichi KAWABATA,Takamitsu NAKAMURA,Yukio SAITO,Daisuke FUJIOKA,Kiyotaka KUGIYAMA

The 77th Annual Scientific Meeting of the Japanase Circulation Society  2013.3 

Remnant Lipoprotein as a Therapeutic Target for Secondary Prevention of Cardiovascular Events in the Era of Drug Eluting Stent Implantation. Major achievement

Takamitsu NAKAMURA,Yoshinobu KITTA,Yukio SAITO,Kenichi KAWABATA,Daisuke FUJIOKA,Junei OBATA,Kiyotaka KUGIYAMA

The 77th Annual Scientific Meeting of the Japanase Circulation Society  2013.3 

Association of Polymorphism in Glutamate-cysteine Ligase Modifier Subunit Gene with Idiopathic Dilated Cardiomyopathy. Major achievement

Kenichi KAWABATA,Yosuke WATANABE,Hideto MISHINA,Kazuhiro WATANABE,Daisuke FUJIOKA,Yukio SAITO,Takamitsu NAKAMURA,Yoshinobu KITTA,Junei OBATA,Kiyotaka KUGIYAMA

The 77th Annual Scientific Meeting of the Japanase Circulation Society  2013.3 

Chronic Depletion of Glutathione Exacerbates Ventricular Remodeling and Dysfunction in Pressure Overloaded Heart in Mice Lacking the Glutamate-Cysteine Ligase Modifier Subunit. Major achievement

Yosuke WATANABE,Kazuhiro WATANABE,Tsuyoshi KOBAYASHI,Yukio SAITO,Daisuke FUJIOKA,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Hideto MISHINA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2012  2012.11 

Measurement of Flow-mediated Endothelial Vasomotor Function Remains Useful for Assessment of Residual Cardiovascular Risk in Patients With CAD After Achievement of LDL-cholesterol Goals by Statin. Major achievement

Yoshinobu KITTA,Takamitsu NAKAMURA,Manabu UEMATSU,Wataru SUGAMATA,Juntaro DEYAMA,Daisuke FUJIOKA,Yukio SAITO,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2012  2012.11 

Plaque Echolucency of Carotid Artery is Useful for Assessment of Residual Cardiovascular Risk in Patients with Coronary Artery Disease after Achievement of LDL-C Goals on Statin Therapy. Major achievement

Manabu UEMATSU,Takamitsu NAKAMURA,Mika FUTAMATA,Tetsuji MOCHIDA,Jun NAKAMURA,Wataru SUGAMATA,Juntaro DEYAMA,Daisuke FUJIOKA,Yukio SAITO,Yoshinobu KITTA,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2012  2012.11 

Endothelial Vasomotor Function in the Brachial Artery is Associated with Long-term Cardiovascular Events in Patients after Implantation of Drug Eluting-Stent. Major achievement

Yoshinobu KITTA,Takamitsu NAKAMURA,Manabu UEMATSU,Wataru SUGAMATA,Juntaro DEYAMA,Daisuke FUJIOKA,Yukio SAITO,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2012  2012.11 

冠動脈疾患における非侵襲的血管エコー検査によるリスク管理 Major achievement

中村　貴光,久木山　清貴

第60回日本心臓病学会学術集会  2012.9 

冠動脈疾患における非侵襲的血管エコー検査によるリスク管理 Major achievement

中村貴光,久木山清貴

第60回日本心臓病学会学術集会　パネルディスカッション  2012.9  日本心臓病学会

Group X Secretory Phospholipase A2 in Neutrophils Plays a Pathogenic Role in Abdominal Aortic Aneurysms in Mice Major achievement

Kazuhiro WATANABE,Daisuke FUJIOKA,Yukio SAITO,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Yosuke WATANABE,Hideto MISHINA,Syun TAMARU,Kiyotaka KUGIYAMA

The 76th Annual Scientific Meeting of the Japanese Circulation Society  2012.3 

Increased Number of Repetitive Balloon Inflations in the Culprit Coronary Artery After Reperfusion During PCI is Associated with Favorable Clinical Outcomes in Patients with ST-Elevation Myocardial Infarction. Major achievement

Takamitsu NAKAMURA,Yoshinobu KITTA,Junei OBATA,Yukio SAITO,Kenichi KAWABATA,Daisuke FUJIOKA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2011  2011.11 

Group X Secretory Phospholipase A2 in Neutrophils Plays a Pathogenic Role in Abdominal Aortic Aneurysms in Mice. Major achievement

Kazuhiro WATANABE,Daisuke FUJIOKA,Yukio SAITO,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Yosuke WATANABE,Hideto MISHINA,Syun TAMARU,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2011  2011.11 

Remnant Lipoproteinemia is a Risk of Non-Culprit Attenuated Coronary Plaques Detected by Grayscale Intravascular Ultrasound in Patients with Acute Coronary Syndromes. Major achievement

Junei OBATA,Yoshinobu KITTA,Yukio SAITO,Takamitsu NAKAMURA,Keita SANO,Daisuke FUJIOKA,Juntaro DEYAMA,Manabu UEMATSU,Kenichi KAWABATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2011  2011.11 

Persistent Insulin Resistance After Optimized Therapy for Atherosclerotic Risk Factors is a Predictor of an Adverse Outcome in Non-Diabetic Patients with Coronary Artery Disease. Major achievement

Yoshinobu KITTA,Takamitsu NAKAMURA,Wataru SUGAMATA,Manabu UEMATSU,Juntaro DEYAMA,Keita SANO,Yukio SAITO,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2011  2011.11 

Remnant Lipoproteinemia is a Predictor of Coronary Events in Patients with Coronary Artery Disease and Chronic Kidney Disease. Major achievement

Yukio SAITO,Takamitsu NAKAMURA,Wataru SUGAMATA,Juntaro DEYAMA,Manabu UEMATSU,Keita SANO,Daisuke FUJIOKA,Yoshinobu KITTA,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2011  2011.11 

Association of Polymorphism in Glutamate-Cysteine Ligase Modifier Subunit Gene with Idiopathic Dilated Cardiomyopathy. Major achievement

Kenichi KAWABATA,Tsuyoshi KOBAYASHI,Daisuke FUJIOKA,Syun TAMARU,Yosuke WATANABE,Kazuhiro WATANABE,Hideto MISHINA,Keita SANO,Takamitsu NAKAMURA,Yukio SAITO,Yoshinobu KITTA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2011  2011.11 

Usefulness of Platelet Retention Assay for Diagnosing Acute Coronary Syndromes and `Predicting Clinical Outcome in Patients with Chest Pain and/or Shortness of Breath. Major achievement

Keita SANO,Wataru SUGAMATA,Juntaro DEYAMA,Manabu UEMATSU,Daisuke FUJIOKA,Takamitsu NAKAMURA,Yukio SAITO,Yoshinobu KITTA,Junei OBATA,Kenichi KAWABATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2011  2011.11 

Contrast-Enhanced Ultrasound Imaging of Carotid Plaque Neovascularization is Useful for Identification of High-Risk Patients for Atherosclerotic Cardiovascular Diseases. Major achievement

Juntaro DEYAMA,Isao TAKISHIMA,Takamitsu NAKAMURA,Manabu UEMATSU,Wataru SUGAMATA,Daisuke FUJIOKA,Keita SANO,Yukio SAITO,Yoshinobu KITTA,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2011  2011.11 

Combined Assessment of Flow-Mediated Dilatation of the Brachial Artery and Brachial-Ankle Pulse Wave Velocity Has an Additive Value on Prediction of Future Cardiovascular Events in Patients with Chronic Coronary Artery Disease. Major achievement

Wataru SUGAMATA,Manabu UEMATSU,Juntaro DEYAMA,Mitsumasa HIRANO,Takamitsu NAKAMURA,Yoshinobu KITTA,Keita SANO,Daisuke FUJIOKA,Yukio SAITO,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2011  2011.11 

Remnant Lipoprotein as a Therapeutic Target for Prevention of Future Cardiovascular Events in Coronary Artery Disease Patients Major achievement

2011.9 

Remnant Lipoprotein as Therapeutic Target for Prevention of Future Cardiovascular Events in Coronary Artery Disease Patients

中村貴光,久木山清貴

2011.9  日本心臓病学会

Coronary Vasomotor Function Following Newer Generation of Bare Metal Stent Overstretch in a Porcine Coronary Model Major achievement

Takamitsu NAKAMURA,Kiyotaka KUGIYAMA,Dongming HOU

The 75th Annual Scientific Meeting of the Japanese Circulation Society  2011.8 

Persistent Impairment of Endothelial Vasomotor Function Adversely Affects Long-term Outcome in Patients with Acute Coronary Syndromes Major achievement

Isao TAKISHIMA,Yoshinobu KITTA,Mitsumasa HIRANO,Takamitsu NAKAMURA,Yuri INO,Juntaro DEYAMA,Aritaka MAKINO,Keita SANO,Yukio SAITO,Junei OBATA,Kenichi KAWABATA,Kiyotaka KUGIYAMA

The 75th Annual Scientific Meeting of the Japanese Circulation Society  2011.8 

Group X Secretory Phospholipase A2 has a Critical Role in Neutrophils Activation and Myocardial Ischemia/reperfusion Injury in Mice Major achievement

Daisuke FUJIOKA,Yukio SAITO,Tsuyoshi KOBAYASHI,Toshiaki YANO,Syun TAMARU,Yosuke WATANABE,Hideto MISHINA,Kazuhiro WATANABE,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Kiyotaka KUGIYAMA

The 75th Annual Scientific Meeting of the Japanese Circulation Society  2011.8 

Group V Secretory Phospholipase A2 Plays an Important Role in the Pathogenesis of Myocardial Ischemia Reperfusion Injury Major achievement

Toshiaki YANO,Daisuke FUJIOKA,Yukio SAITO,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Kazuhiro WATANABE,Yosuke WATANABE,Hideto MISHINA,Syun TAMARU,Kiyotaka KUGIYAMA

The 75th Annual Scientific Meeting of the Japanese Circulation Society  2011.8 

Sirolimus-eluting-Stent Implantation at Proximal Site Inhibits In-stent Restenosis in Bare Metal Stent Placed at Distal Site of Same Coronary Artery Major achievement

Junei OBATA,Yoshinobu KITTA,Yukio SAITO,Takamitsu NAKAMURA,Keita SANO,Mitsumasa HIRANO,Kiyotaka KUGIYAMA

The 75th Annual Scientific Meeting of the Japanese Circulation Society  2011.8 

Remnant Lipoproteinemia is an Independent Predictor of Cardiovascular Events in Patients with Diabetes Mellitus or Impaired Glucose Tolerance Major achievement

Mitsumasa HIRANO,Takamitsu NAKAMURA,Yoshinobu KITTA,Keita SANO,Yukio SAITO,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

The 75th Annual Scientific Meeting of the Japanese Circulation Society  2011.8 

High Levels of Macrophage Migration Inhibitory Factor Adversely Affect in Heart Failure Patients with Impaired Glucose Tolerance or Diabetes mellitus Major achievement

Aritaka MAKINO,Takamitsu NAKAMURA,Mitsumasa HIRANO,Kiyotaka KUGIYAMA

The 75th Annual Scientific Meeting of the Japanese Circulation Society  2011.8 

Vascular Function of Bioabsorbable Stented Site after Complete Absorption of the Stent. Major achievement

Li J,Yue J,Hou D,Matsumoto D,Takamitsu NAKAMURA,Refat JABARA,Spencer B. KING III,Singh J,Chronos N

CRT 2011  2011.2 

Vascular Function of Bioabsorbable Stented Site after Complete Absorption of the Stent Major achievement

Jinsheng Li,Jianing Yue,Dongming Hou,Daisuke Musimuto,Takamitsu Nakamura,Refat Jabara,Spencer B. King III,Jaipal Singh,Nicolas Chronos

CRT 2011  2011.2 

Persistent Impairment of Endothelial Vasomotor Function Adversely Affects Long-term Outcome in Patients with Acute Coronary Syndromes. Major achievement

Isao TAKISHIMA,Yoshinobu KITTA,Mitsumasa HIRANO,Takamitsu NAKAMURA,Yuri INO,Juntaro DEYAMA,Aritaka MAKINO,Keita SANO,Yukio SAITO,Junei OBATA,Kenichi KAWABATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2010  2010.11 

Optical Coherence Tomography and Histopathological Assessment of Delayed Arterial Healing After Drug-Eluting Stent Implant Using in Pig Coronary Model Major achievement

Daisuke Matsumoto,Toshiro Shinke,Takamitsu Nakamura,Dongming Hou,Nicolas Chronos

American Heart Association 2010  2010.11 

Vasomotor Function Following Paclitaxel-Coated Balloon Post-Dilatation in Porcine Coronary Stent Model Major achievement

Takamitsu Nakamura,Brigitta C Brott,Xinhua Yin,Jinsheng Li,Jack P Chen,Jaial Singh,Spencer B King,Nicolas Chronos,Dongming Hou

American Heart association 2010  2010.11 

A Time-course Study of Vasomotor Function After Implantation of Novel Paclitaxel-eluting Stent in Rabbit Iliac Arteries Major achievement

Takamitsu Nakamura,Irena Brants,Dawn Winsor-Hines,Nicolas Chronos,Dongming Hou

American Heart Association 2010  2010.11 

Overlapping Sirolimus- but not Zotarolimus-eluting Stents have Adverse Effects on both Epicardial and Microcirculatory Endothelial Function in Porcine Coronary Arteries. Major achievement

Takamitsu NAKAMURA,Brants I,Panchal D,Li J,Chen JP,Singh J,Chronos N,Hou D

Euro PCR  2010.5 

Endothelium-dependent vasomotor dysfunction following overlapping sirolimus- but not zotarolimus-eluting stents is associated local oxidative stress in a porcine coronary model. Major achievement

Takamitsu NAKAMURA,Natarajan K,Yue J,Li J,Goodchild T,Singh J,Chronos N,Hou D

Euro PCR  2010.5 

TIMI2 Flow Results in Significantly Higher Microcirculatory Resistance as Compared to TIMI3 Flow in a Swine Myocardial Infarction Model. Major achievement

Yin X,Takamitsu NAKAMURA,Li J,Chen JP,Matheny R,Chronos N,Hou D

Annual scientific sessions of The Society for Cardiovascular Angiography and Interventions  2010.5 

Percutaneous Induced Left Ventricle Myocardial Infarction with Re-open LAD in a Clinical Relevant Animal Model. Major achievement

Li J,Yin X,Takamitsu NAKAMURA,Lakshmana P,Brants I,Frohwein S,Chen JP,Chronos N,Matheny R,Hou D

American College of Cardiology 59h Annual Scientific Session  2010.3 

Evaluation of Biocompatibility and Delivery Performance with Novel Self-Expanding Stents in Pig Iliac Model. Major achievement

Matsumoto D,Shinke T,Takamitsu NAKAMURA,Abrutis A,Li J,Chronos N,Hou D

CRT 2010  2010.2 

Long Novel Self-expanding Misago In Comparison With Smart Stent: 6-month Results In Swine Ilio-femoral Model. Major achievement

Matsumoto D,Shinke T,Takamitsu NAKAMURA,Yin X,Li J,Abrutis A,Chronos N,Hou D

CRT 2010  2010.2 

Quantitative intravascular ultrasound and immunohistochemical analyses of a novel bioabsorable stent in a porcine coronary model. Major achievement

Takamitsu NAKAMURA,Shinke T,Yin X,Geva S,Brants I,Chen JP,Chronos N,Hou D

TCT  2009.9 

Endothelial Vasomotor Dysfunction in Brachial Artery Predicts Development of Early Renal Dysfunction in Hypertensive Patients. Major achievement

Mitsumasa HIRANO,Takamitsu NAKAMURA,Yoshinobu KITTA,Isao TAKISHIMA,Aritaka MAKINO,Keita SANO,Yasushi KODAMA,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2008  2008.11 

Mice Lacking the Glutamate-Cysteine Ligase Modifier Subunit are Susceptible to Myocardial Ischemia-Reperfusion Injury Through Reduction of Mitochondrial Glutathione. Major achievement

Tsuyoshi KOBAYASHI,Kenichi KAWABATA,Yukio SAITO,Daisuke FUJIOKA,Kazuto NAKAMURA,Toshiaki YANO,Ryota SATO,Kazuhiro WATANABE,Yosuke WATANABE,Junei OBATA,Takamitsu NAKAMURA,Sadahiro ITO,Timothy P DALTON,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2008  2008.11 

Late Catch-Up Recovery from Endothelial Vasomotor Dysfunction in Infarct-Related Coronary Artery Treated with Sirolimus-Eluting Stent in Patients with Acute Myocardial Infarction. Major achievement

Junei OBATA,Yoshinobu KITTA,Yasushi KODAMA,Takamitsu NAKAMURA,Kenichi KAWABATA,Keita SANO,Mitsumasa HIRANO,Yukio SAITO,Kazuto NAKAMURA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2008  2008.11 

A Prospective Randomized Comparative Trial of Bezafibrate and Pravastatin in Patients with Coronary Artery Disease and High Remnant Lipoprotein Levels. Major achievement

Keita SANO,Takamitsu NAKAMURA,Isao TAKISHIMA,Aritaka MAKINO,Mitsumasa HIRANO,Yasushi KODAMA,Yoshinobu KITTA,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2008  2008.11 

Progression of Urine Albumin Excretion Despite of Optimized Therapies to Reduce Atherosclerotic Risk Factors has an Adverse Outcome in Patients with Coronary Artery Disease. Major achievement

Yoshinobu KITTA,Mitsumasa HIRANO,Takamitsu NAKAMURA,Yasushi KODAMA,Keita SANO,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2008  2008.11 

High Plasma Levels of Stromal Cell-Derived Factor-1 Alpha Predict a Worse Prognosis in Patients with Chronic Heart Failure. Major achievement

Yasushi KODAMA,Aritaka MAKINO,Keita SANO,Isao TAKISHIMA,Mitsumasa HIRANO,Takamitsu NAKAMURA,Yukio SAITO,Kazuto NAKAMURA,Yoshinobu KITTA,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2008  2008.11 

High Plasma Levels of Endogenous Free Dopamine Predict an Adverse Outcome in Patients with Heart Disease and Chronic Kidney Disease. Major achievement

Keita SANO,Yasushi KODAMA,Mitsumasa HIRANO,Isao TAKISHIMA,Aritaka MAKINO,Takamitsu NAKAMURA,Yoshinobu KITTA,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2008  2008.11 

Rapid Progression of Intima-Media Thickness of Carotid Plaque Despite Individualized and Optimized Therapy for Cardiovascular Risk Factors Predicts a Worse Outcome in Patients with Coronary Artery Disease. Major achievement

Mitsumasa HIRANO,Yoshinobu KITTA,Takamitsu NAKAMURA,Isao TAKISHIMA,Aritaka MAKINO,Keita SANO,Yasushi KODAMA,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2008  2008.11 

Combined Assessment of Intima-Media Thickness and Echolucency of an Atherosclerotic Plaque in Carotid Artery has an Additive Value on Prediction of Future Coronary Events in Patients with Coronary Artery Disease and Carotid Atherosclerosis. Major achievement

Mitsumasa HIRANO,Takamitsu NAKAMURA,Yoshinobu KITTA,Isao TAKISHIMA,Aritaka MAKINO,Keita SANO,Yasushi KODAMA,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2008  2008.11 

High Remnant Lipoprotein Levels Are a Strong Predictor of Cardiovascular Events in Patients with Chronic Coronary Artery Disease and Metabolic Syndrome after Achieving LDL-Cholesterol Goals. Major achievement

Mitsumasa HIRANO,Takamitsu NAKAMURA,Yoshinobu KITTA,Isao TAKISHIMA,Aritaka MAKINO,Keita SANO,Yasushi KODAMA,Kenichi KAWABATA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2008  2008.11 

High Plasma Levels of Macrophage Migration Inhibitory Factor Predict Future Cardiovascular Events in Patients with Impaired Glucose Tolerance or Type 2 Diabetes Mellitus. Major achievement

Aritaka MAKINO,Yasushi KODAMA,Isao TAKISHIMA,Mitsumasa HIRANO,Keita SANO,Takamitsu NAKAMURA,Yoshinobu KITTA,Junei OBATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2008  2008.11 

Remnant Lipoprotein is Superior to Non-HDL-C for Prediction of Cardiovascular Events in Patients with CAD after Achievement of LDL-C Goals. Major achievement

Takamitsu NAKAMURA,Mitsumasa HIRANO,Yoshinobu KITTA,Yasushi KODAMA,Junei OBATA,Hajime TAKANO,Kenichi KAWABATA,Akira MENDE,Keita SANO,Kiyotaka KUGIYAMA

The 72th Annual Scientific Meeting of the Japanese Circulation Society  2008.3 

Persistent Impairment of Endothelial Function is a Predictor of Future Ischemic Stroke in Patients with Coronary Artery Disease. Major achievement

Yoshinobu KITTA,Hajime TAKANO,Junei OBATA,Kenichi KAWABATA,Yasushi KODAMA,Akira MENDE,Takamitsu NAKAMURA,Keita SANO,Mitsumasa HIRANO,Kiyotaka KUGIYAMA

The 72th Annual Scientific Meeting of the Japanese Circulation Society  2008.3 

Association of Polymorphism in Glutamate-Cysteine Ligase Gene with Myocardial Infarction and Coronary Vasomotor Dysfunction in smokers. Major achievement

Kenichi KAWABATA,Tsuyoshi KOBAYASHI,Toshiaki YANO,Daisuke FUJIOKA,Mitsumasa HIRANO,Keita SANO,Akira MENDE,Yukio SAITO,Takamitsu NAKAMURA,Yasushi KODAMA,Yoshinobu KITTA,Junei OBATA,Hajime TAKANO,Kiyotaka KUGIYAMA

The 72th Annual Scientific Meeting of the Japanese Circulation Society  2008.3 

High Plasma Levels of Free Dopamine Predict an Adverse Outcome in Patients with Heart Failure. Major achievement

Keita SANO,Tsuyoshi KOBAYASHI,Mitsumasa HIRANO,Daisuke FUJIOKA,Takamitsu NAKAMURA,Akira MENDE,Yukio SAITO,Yoshinobu KITTA,Yasushi KODAMA,Kenichi KAWABATA,Junei OBATA,Hajime TAKANO,Kiyotaka KUGIYAMA

The 72th Annual Scientific Meeting of the Japanese Circulation Society  2008.3 

Endothelial Vasomotor Dysfunction in Brachial Artery Predicts Early Renal Dysfunction in Patients with Coronary Artery Disease. Major achievement

Takamitsu NAKAMURA,Mitsumasa HIRANO,Yoshinobu KITTA,Yasushi KODAMA,Junei OBATA,Hajime TAKANO,Kenichi KAWABATA,Keita SANO,Akira MENDE,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2007  2007.11 

Polymorphisms of Glutamate-cysteine Ligase Modifier Subunit and Catalytic Subunit Genes Increase the Susceptibility of Smokers to Myocardial Infarction and Coronary Endothelial Vasomotor Dysfunction. Major achievement

Kenichi KAWABATA,Tsuyoshi KOBAYASHI,Toshiaki YANO,Daisuke FUJIOKA,Mitsumasa HIRANO,Keita SANO,Takamitsu NAKAMURA,Akira MENDE,Yukio SAITO,Yasushi KODAMA,Yoshinobu KITTA,Junei OBATA,Hajime TAKANO,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2007  2007.11 

High Remnant Lipoprotein Levels Adversely Affect Short- and Long-term Outcomes for Patients with Acute Myocardial Infarction and Type 2 Diabetes Mellitus. Major achievement

Takamitsu NAKAMURA,Mitsumasa HIRANO,Yoshinobu KITTA,Yasushi KODAMA,Akira MENDE,Junei OBATA,Kenichi KAWABATA,Hajime TAKANO,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2007  2007.11 

Measurement of Platelet Retention Rate in Collagen-coated Beads Column, a Newly Developed Method to Measure Platelet Function, is Useful for Assessment of Clinical Efficacy of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease. Major achievement

Akira MENDE,Mitsumasa HIRANO,Yukio SAITO,Daisuke FUJIOKA,Takamitsu NAKAMURA,Yoshinobu KITTA,Yasushi KODAMA,Kenichi KAWABATA,Junei OBATA,Hajime TAKANO,Keita SANO,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2007  2007.11 

Persistent Impairment of Endothelial Function in the Brachial Artery is a Predictor of Future Ischemic Stroke in Patients with Coronary Artery Disease. Major achievement

Yoshinobu KITTA,Takamitsu NAKAMURA,Mitsumasa HIRANO,Yasushi KODAMA,Hajime TAKANO,Kenichi KAWABATA,Junei OBATA,Akira MENDE,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2007  2007.11 

Sirolimus-eluting Stent Implantation at Proximal Site Inhibits In-stent Restenosis in Bare Metal Stent Placed at Distal Site of de novo Lesion in Same Coronary Artery. Major achievement

Hajime TAKANO,Junei OBATA,Yoshinobu KITTA,Yasushi KODAMA,Akira MENDE,Takamitsu NAKAMURA,Keita SANO,Mitsumasa HIRANO,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2007  2007.11 

Long-lasting Impairment of Endothelial Vasomotor Function in Infarct-related Coronary Artery Treated with Sirolimus-eluting Stent in Patients with Acute Myocardial Infarction. Major achievement

Junei OBATA,Hajime TAKANO,Yoshinobu KITTA,Yasushi KODAMA,Akira MENDE,Takamitsu NAKAMURA,Mitsumasa HIRANO,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2007  2007.11 

Remnant Lipoprotein is Superior to Non-HDL-cholesterol for Prediction of Cardiovascular Events in Patients with Coronary Artery Disease after Achievement of LDL-cholesterol Goals. Major achievement

Takamitsu NAKAMURA,Mitsumasa HIRANO,Yoshinobu KITTA,Yasushi KODAMA,Junei OBATA,Hajime TAKANO,Kenichi KAWABATA,Akira MENDE,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2007  2007.11 

High Plasma Levels of Stromal Cell-Derived Factir-1 alpha Predict Future Cardiovascular Events in Patients with Previous Myocardial Infarction. Major achievement

Yasushi KODAMA,Keita SANO,Mitsumasa HIRANO,Takamitsu NAKAMURA,Akira MENDE,Yoshinobu KITTA,Junei OBATA,Hajime TAKANO,Toshiaki YANO,Tsuyoshi KOBAYASHI,Daisuke FUJIOKA,Yukio SAITO,Kenichi KAWABATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2007  2007.11 

Atorvastatin Increases Plasma sFlt-1 and Decreases VEGF and PlGF in Association with Improvement of Ventricular Function in Acute Myocardial Infarction. Major achievement

Yasushi KODAMA,Yoshinobu KITTA,Takamitsu NAKAMURA,Hajime TAKANO,Ken UMETANI,Daisuke FUJIOKA,Yukio SAITO,Kenichi KAWABATA,Junei OBATA,Akira MENDE,Tsuyoshi KOBAYASHI,Kiyotaka KUGIYAMA

The 71th Annual Scientific Meeting of the Japanese Circulation Society  2007.3 

Sirolimus-eluting Stent Implantation Adversely Affects Microvascular Endothelial Function in the Infarct-Related Coronary Artery in Patients with Acute Anterior Myocardial Infarction. Major achievement

Junei OBATA,Hajime TAKANO,Yoshinobu KITTA,Yasushi KODAMA,Makoto ABE,Akira MENDE,Takamitsu NAKAMURA,Masahiko IWAOKA,Kenichi KAWABATA,Mitsumasa HIRANO,Kiyotaka KUGIYAMA

The 71th Annual Scientific Meeting of the Japanese Circulation Society  2007.3 

Persistent Impairment of Endothelial Function Has an Adverse Outcome in Patients with Coronary Artery Disease. Major achievement

Yoshinobu KITTA,Hajime TAKANO,Takamitsu NAKAMURA,Yasushi KODAMA,Junei OBATA,Kenichi KAWABATA,Akira MENDE,Makoto ABE,Masahiko IWAOKA,Kiyotaka KUGIYAMA

The 71th Annual Scientific Meeting of the Japanese Circulation Society  2007.3 

Combined Ultrasound Assessment of Brachial Endothelial Vasomotor Function and Carotid Plaque Echolucency Predicts Cardiovascular Events in Metabolic Syndrome. Major achievement

Takamitsu NAKAMURA,Yoshinobu KITTA,Masahiko IWAOKA,Hajime TAKANO,Yasushi KODAMA,Kenichi KAWABATA,Junei OBATA,Akira MENDE,Makoto ABE,Kiyotaka KUGIYAMA

The 71th Annual Scientific Meeting of the Japanese Circulation Society  2007.3 

Adiponectin is Released from Heart in Patients with Non-Ischemic Heart Failure. Major achievement

Hajime TAKANO,Yasushi KODAMA,Yoshinobu KITTA,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Makoto ABE,Akira MENDE,Masahiko IWAOKA,Kiyotaka KUGIYAMA

The 71th Annual Scientific Meeting of the Japanese Circulation Society  2007.3 

Association of High Levels of Plasma Free Dopamine with Future Coronary Events in Patients with Coronary Artery Disease. Major achievement

Makoto ABE,Masahiko IWAOKA,Takamitsu NAKAMURA,Yoshinobu KITTA,Hajime TAKANO,Yasushi KODAMA,Kenichi KAWABATA,Junei OBATA,Akira MENDE,Tsuyoshi KOBAYASHI,Daisuke FUJIOKA,Yukio SAITO,Kiyotaka KUGIYAMA

The 71th Annual Scientific Meeting of the Japanese Circulation Society  2007.3 

Combined Ultrasound Assessment of Brachial Endothelial Vasomotor Function and Carotid Plaque Echolucency has an Additive Value on the Prediction of Cardiovascular Events in Metabolic Syndrome. Major achievement

Takamitsu NAKAMURA,Yoshinobu KITTA,Masahiko IWAOKA,Hajime TAKANO,Yasushi KODAMA,Kenichi KAWABATA,Junei OBATA,Akira MENDE,Makoto ABE,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2006  2006.11 

Persistent Impairment of Endothelial Function is a Predictor of Adverse Outcomes in Patients with Coronary Artery Disease. Major achievement

Yoshinobu KITTA,Hajime TAKANO,Takamitsu NAKAMURA,Yasushi KODAMA,Kenichi KAWABATA,Junei OBATA,Akira MENDE,Masahiko IWAOKA,Makoto ABE,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2006  2006.11 

Adiponectin is Released from the Heart in Patients with Non-Ischemic Heart Failure. Major achievement

Hajime TAKANO,Yasushi KODAMA,Junei OBATA,Yoshinobu KITTA,Takamitsu NAKAMURA,Ken UMETANI,Kenichi KAWABATA,Akira MENDE,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2006  2006.11 

Sirolimus-eluting Stent Implantation Adversely Affects Microvascular Endothelial Function in the Infarct-related Coronary Artery in Patients with Acute Anterior Myocardial Infarction. Major achievement

Junei OBATA,Takamitsu NAKAMURA,Makoto ABE,Akira MENDE,Yoshinobu KITTA,Yasushi KODAMA,Kenichi KAWABATA,Hajime TAKANO,Ken UMETANI,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2006  2006.11 

Patients with Low Plasma Levels Apolipoprotein A-1 Have a Worse Prognosis in Non-ischemic Heart Failure. Major achievement

Masahiko IWAOKA,Makoto ABE,Takamitsu NAKAMURA,Akira MENDE,Yoshinobu KITTA,Yasushi KODAMA,Junei OBATA,Kenichi KAWABATA,Ken UMETANI,Hajime TAKANO,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2006  2006.11 

High Prevalence of Paroxysmal Atrial Fibrillation in Metabolic Syndrome. Major achievement

Ken UMETANI,Takamitsu NAKAMURA,Yoshinobu KITTA,Akira MENDE,Hajime TAKANO,Kenichi KAWABATA,Junei OBATA,Yasushi KODAMA,Makoto ABE,Masahiko IWAOKA,Kiyotaka KUGIYAMA

The 70th Annual Scientific Meeting of the Japanese Circulation Society  2006.3 

Role of Adiponectin Receptors in Endothelin-induced Cellular Hypertrophy in Cultured Cardiomyocytes and Their Expression in Infarcted Heart. Major achievement

Daisuke FUJIOKA,Kenichi KAWABATA,Yukio SAITO,Tsuyoshi KOBAYASHI,Masahiko IWAOKA,Takamitsu NAKAMURA,Makoto ABE,Akira MENDE,Yasushi KODAMA,Yoshinobu KITTA,Junei OBATA,Hajime TAKANO,Ken UMETANI,Kiyotaka KUGIYAMA

The 70th Annual Scientific Meeting of the Japanese Circulation Society  2006.3 

Suppression of Interleukin-8 Levels in Coronary Circulation after Atorvastatin is Associated with Improvement of Ventricular Function after Acute Myocardial Infarction. Major achievement

Yasushi KODAMA,Hajime TAKANO,Takamitsu NAKAMURA,Ken UMETANI,Yoshinobu KITTA,Junei OBATA,Kenichi KAWABATA,Akira MENDE,Kiyotaka KUGIYAMA

The 70th Annual Scientific Meeting of the Japanese Circulation Society  2006.3 

Low Transcardiac Uptake of Adiponectin is an Independent Risk Factor for Endothelial Dysfunction in Human Large and Resistance Coronary Arteries. Major achievement

Hajime TAKANO,Yasushi KODAMA,Yoshinobu KITTA,Ken UMETANI,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Akira MENDE,Makoto ABE,Masahiko IWAOKA,Kiyotaka KUGIYAMA

The 70th Annual Scientific Meeting of the Japanese Circulation Society  2006.3 

Decrease in Transcardiac Gradient of Plasma VEGF Levels is Associated with an Impaired Coronary Blood Flow Response in Humans. Major achievement

Akira MENDE,Hajime TAKANO,Yasushi KODAMA,Takamitsu NAKAMURA,Ken UMETANI,Daisuke FUJIOKA,Tsuyoshi KOBAYASHI,Yukio SAITO,Makoto ABE,Kenichi KAWABATA,Junei OBATA,Yoshinobu KITTA,Kiyotaka KUGIYAMA

The 70th Annual Scientific Meeting of the Japanese Circulation Society  2006.3 

High Serum Levels of Remnant Lipoproteins Predict Ischemic Stroke in Metabolic Syndrome. Major achievement

Takamitsu NAKAMURA,Yoshinobu KITTA,Hajime TAKANO,Ken UMETANI,Yasushi KODAMA,Kenichi KAWABATA,Junei OBATA,Akira MENDE,Kiyotaka KUGIYAMA

The 70th Annual Scientific Meeting of the Japanese Circulation Society  2006.3 

Low Adiponectin Levels Predict In-stent Restenosis after Stenting in Native Coronary Arteries. Major achievement

Yoshinobu KITTA,Yasushi KODAMA,Hajime TAKANO,Ken UMETANI,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Akira MENDE,Kiyotaka KUGIYAMA

The 70th Annual Scientific Meeting of the Japanese Circulation Society  2006.3 

Low Adiponectin Levels Predict Late In-Stent Restenosis after Stenting in Native Coronary Arteries. Major achievement

Yoshinobu KITTA,Yasushi KODAMA,Hajime TAKANO,Ken UMETANI,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Akira MENDE,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2005  2005.11 

High Serum Levels of Remnant Lipoproteins Predict Ischemic Stroke in Metabolic Syndrome. Major achievement

Takamitsu NAKAMURA,Yoshinobu KITTA,Hajime TAKANO,Ken UMETANI,Yasushi KODAMA,Kenichi KAWABATA,Junei OBATA,Akira MENDE,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2005  2005.11 

Low Transcardiac Uptake of Adiponectin is an Independent Risk Factor for Endothelial Vasomotor Dysfunction in Human Large and Resistance Coronary Arteries. Major achievement

Hajime TAKANO,Yasushi KODAMA,Yoshinobu KITTA,Ken UMETANI,Takamitsu NAKAMURA,Junei OBATA,Kenichi KAWABATA,Akira MENDE,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2005  2005.11 

Aspiration of Intracoronary Thrombus before Stenting Increases Cardiac Production of Hepatocyte Growth Factor in AMI. Major achievement

Hajime TAKANO,Ken UMETANI,Yasushi KODAMA,Kenichi KAWABATA,Yoshinobu KITTA,Yoshihide ICHIGI,Takamitsu NAKAMURA,Kiyotaka KUGIYAMA

The 69th Annual Scientific Meeting of the Japanese Circulation Society  2005.3 

Increase in Circulating Levels of Adiponectin by Statin and Fibrate in Patients with Coronary Artery Disease. Major achievement

Takamitsu NAKAMURA,Yasushi KODAMA,Hajime TAKANO,Ken UMETANI,Daisuke FUJIOKA,Kenichi KAWABATA,Junei OBATA,Yoshinobu KITTA,Yoshihide ICHIGI,Akira MENDE,Kiyotaka KUGIYAMA

The 69th Annual Scientific Meeting of the Japanese Circulation Society  2005.3 

Remnant Hyperlipoproteinemia is a Risk Factor for Endothelial Dysfunction and Coronary Artery Disease in Metabolic Syndrome. Major achievement

Takamitsu NAKAMURA,Hajime TAKANO,Ken UMETANI,Kenichi KAWABATA,Junei OBATA,Yoshinobu KITTA,Yasushi KODAMA,Akira MENDE,Yoshihide ICHIGI,Kiyotaka KUGIYAMA

The 69th Annual Scientific Meeting of the Japanese Circulation Society  2005.3 

Increased Ambulatory Pulse Pressure is a Strong Risk Factor for Coronary Endothelial Vasomotor Dysfunction. Major achievement

Yoshihide ICHIGI,Hajime TAKANO,Ken UMETANI,Yoshinobu KITTA,Takamitsu NAKAMURA,Yasushi KODAMA,Kenichi KAWABATA,Akira MENDE,Hiroshi YOSHIDA,Kiyotaka KUGIYAMA

The 69th Annual Scientific Meeting of the Japanese Circulation Society  2005.3 

Increase in ambulatory pulse pressure is a strong risk of coronary endothelial vasomotor dysfunction irrespective of hypertension. Major achievement

Yoshihide ICHIGI,Hajime TAKANO,Ken UMETANI,Yoshinobu KITTA,Takamitsu NAKAMURA,Yasushi KODAMA,Kenichi KAWABATA,Akira MENDE,Hiroshi YOSHIDA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2004  2004.11 

Blunted reduction of pulse pressure during nighttime is associated with left ventricular hypertrophy in elderly hypertensive patients. Major achievement

Takashi IIDA,Yoshihide ICHIGI,Ken UMETANI,Hajime TAKANO,Takamitsu NAKAMURA,Yoshinobu KITTA,Yasushi KODAMA,Akira MENDE,Kenichi KAWABATA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2004  2004.11 

Increase in circulating levels of adiponectin by statin and fibrate in patients with coronary artery disease. Major achievement

Takamitsu NAKAMURA,Yasushi KODAMA,Hajime TAKANO,Ken UMETANI,Akira MENDE,Yoshihide ICHIGI,Kenichi KAWABATA,Yoshinobu KITTA,Hiroshi YOSHIDA,Kiyotaka KUGIYAMA

American Heart Association Scientific Sessions 2004  2004.11 

当院における左冠動脈主幹部急性冠症候群の治療成績 Major achievement

橘田　吉信,高野　一,中村　貴光,兒玉　康史,一木　美英,山本　君男,尾畑　純栄,川端　健一,長田　満,梅谷　健,久木山　清貴,松本　雅彦,進藤　俊哉,福田　尚司,井上　秀範,葛　仁猛

第24回日本心血管インターベンション学会関東甲信越地方会  2004.5 

Thrombuster使用後の急性心筋梗塞症例の臨床像の特徴 Major achievement

中村　貴光,高野　一,橘田　吉信,兒玉　康史,一木　美英,山本　君男,尾畑　純栄,川端　健一,長田　満,梅谷　健,久木山　清貴,松本　雅彦,進藤　俊哉,福田　尚司,井上　秀範,葛　仁猛

第24回日本心血管インターベンション学会関東甲信越地方会  2004.5 

閉塞性動脈硬化症に基づく進行性の下肢壊死に対して、自己骨髄単核球細胞移植による血管新生治療が奏効した1例 Major achievement

長田　満,長谷部　秀幸,兒玉　康史,藤岡　大佑,中村　貴光,三森　徹,中村　和人,橘田　吉信,一木　美英,山本　君男,尾畑　純栄,川端　健一,柳　光章,高野　一,梅谷　健,久木山　清貴,佐野　壮一

第30回山梨総合医学会  2004.3 

当院における植え込み型除細動器による治療経験 Major achievement

山本　君男,梅谷　健,藤岡　大佑,中村　貴光,兒玉　康史,橘田　吉信,一木　美英,川端　健一,尾畑　純栄,長田　満,高野　一,久木山　清貴

第30回山梨総合医学会  2004.3 

No reflow診断後oozing cardiac raptureに進展した高齢者の急性心筋梗塞の1症例 Major achievement

中村　貴光,橘田　吉信,兒玉　康史,一木　美英,山本　君男,尾畑　純栄,川端　健一,長田　満,高野　一,梅谷　健,久木山　清貴,松本　雅彦,進藤　俊哉,福田　尚司,井上　秀範

第30回山梨総合医学会  2004.3 

当院における左冠動脈主幹部急性冠症候群の治療成績 Major achievement

橘田　吉信,中村　貴光,兒玉　康史,一木　美英,山本　君男,尾畑　純栄,川端　健一,長田　満,高野　一,梅谷　健,久木山　清貴,松本　雅彦,進藤　俊哉,福田　尚司,井上　秀範

第30回山梨総合医学会  2004.3 

ステント遅発性血栓症閉塞にて再梗塞を生じた1症例 Major achievement

橘田　吉信,中村　貴光,兒玉　康史,一木　美英,山本　君男,尾畑　純栄,川端　健一,長田　満,高野　一,梅谷　健,久木山　清貴

第30回山梨総合医学会  2004.3 

ペーシングレートの変更により塩酸ニフェカラントが著効した持続性心室性頻拍 Major achievement

兒玉　康史,梅谷　健,藤岡　大佑,佐野　圭太,中村　貴光,橘田　吉信,一木　美英,尾畑　純栄,川端　健一,長田　満,高野　一,久木山　清貴,杉本武史

第189回循環器病学会関東甲信越地方会  2003.9 

一般病院における市中肺炎180例の検討 重症度と入院期間の相関性および死亡例の検討 Major achievement

赤尾　正樹,中村　貴光,齊藤　幸生,小澤　克良,川口　哲男,南部　敦史

第28回山梨総合医学会  2002.3 

市立甲府病院における運動負荷心エコー図検査229例の検討 Major achievement

齊藤　幸生,佐野　壮一,中村　貴光,小澤　克良,久木山　清貴

第28回山梨総合医学会  2002.3 

Mycoplasm Pneumoniae 肺炎の経過中に横断性脊髄炎を発症した一例 Major achievement

赤尾　正樹,中村　貴光,小澤　克良,角田　伸一,久木山　清貴

第148回日本呼吸器学会関東地方会  2002.2 

左心室内での電極カテーテル操作中に完全房室ブロックをきたした完全左脚ブロックの1例 Major achievement

齊藤　幸生,佐野　壮一,中村　貴光,小澤　克良,久木山　清貴

第14回臨床不整脈研究会  2002.1 

失神発作をともなった先天性QT延長症候群の1例 Major achievement

齊藤　幸生,佐野　壮一,中村　貴光,小澤　克良,久木山　清貴

第182回日本循環器学会関東甲信越地方会  2001.12 

短期間で形態的変化を認めた左心室緻密化不全の1例 Major achievement

中村　貴光,佐野　壮一,齊藤　幸生,小澤　克良,久木山　清貴

第182回日本循環器学会関東甲信越地方会  2001.12 

内視鏡的に治療し得た気管支結石症の1例 Major achievement

赤尾　正樹,中村　貴光,齊藤　幸生,小澤　克良,川口　哲男

第140回結核病学会関東支部会・第147回日本呼吸器学会関東地方会合同学会  2001.11 

透析後にtorsade de pointesを来したQT延長症候群の一例 Major achievement

中村　貴光,沢登　貴雄,齊藤　幸生,清水　しの,小川　竜次,飯田　隆史,長田　満,梅谷　健,井尻　裕,小森　貞嘉

日本内科学会 第491回関東地方会  2001.6