Updated on 2024/04/08

写真a

 
Ito Sadahiro
 
Organization
Graduate Faculty of Interdisciplinary Research Faculty of Medicine Basic Science for Clinical Medicine (Center for Life Science Research) Assistant Professor
Title
Assistant Professor
Contact information
メールアドレス

Research History

  • 山梨大学助教(総合分析実験センター)

    2009.4

  • 山梨大学助教(総合分析実験センター)

    2009.4

  • 山梨大学助手(総合分析実験センター)

    2002.10

  • 山梨大学助手(総合分析実験センター)

    2002.10

  • 山梨医科大学助手(総合分析実験センター)

    2002.4

  • 山梨医科大学助手(総合分析実験センター)

    2002.4

  • Research Associate, The Center for

    2002 - 2003

  • 山梨医科大学技術系職員(生化学第1)

    1984.4

  • 山梨医科大学技術系職員(生化学第1)

    1984.4

  • Technical Official, Yamanashi Medical

    1984 - 2001

  • University

  • Life Science Research, Yamanashi

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Education

  • Hirosaki University

    1980.4 - 1984.3

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    Country: Japan

  • Hirosaki University   Science   Chemistry, Physical Chemistry

    - 1984

  • University of Yamanashi

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    Country: Japan

    Course: Doctor course

Degree

  • 博士(医科学) ( 2009.3   山梨大学 )

  • 学士(化学) ( 1984.3   弘前大学 )

Research Areas

  • Life Science / Genetics

  • Life Science / Genetics

Research Interests

  • 遺伝・ゲノム動態

  • Developmental Biotechnology

  • Molecular Biology

  • Molecular Genetics

Subject of research

  • The generation of the mouse models of human disease by the developmental engineering.

  • Using the mouse models of human disease, the development of treatments for the genetic diseases.

Research Projects

  • 異なる遺伝子背景に起因する抗核抗体値上昇機構の解析

    2018.4 - 2021.3

    独立行政法人日本学術振興会  科学研究費助成事業  基礎研究(C)(一般)

    伊藤禎洋、神沼修、長友啓明

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    Authorship:Principal investigator  Type of fund::Science research expense

  • Production of animal models for human diseases with embryo engineering

    2002

    Research Support Activities for Life Science 

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    Grant type:Competitive 

  • Amyloidosis

    1993

    Gene Science Research 

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    Grant type:Competitive 

  • 発生工学による疾患モデルマウスの作製

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    Grant type:Competitive 

  • Using the mouse models of human disease, the development of treatments for the genetic diseases.

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    Grant type:Competitive 

  • 疾患モデルマウスを用いた、遺伝病の治療法の開発

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    Grant type:Competitive 

  • The generation of the mouse models of human disease by the developmental engineering.

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    Grant type:Competitive 

  • Production of animal models for human diseases with embryo engineering

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    Grant type:Competitive 

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Papers

  • A Ser75-to-Asp phospho-mimicking mutation in Src accelerates ageing-related loss of retinal ganglion cells in mice Reviewed

    Kenji Kashiwagi, Sadahiro Ito, Shuichiro Maeda, and Goro Kato

    Scientific Reports   2017.12( ISSN:2045-2322 )

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Mice lacking the glutamate-cysteine ligase modifier subunit are susceptible to myocardial ischaemia-reperfusion injury. Reviewed Major achievement

    Tsuyoshi KOBAYASHI,Yosuke WATANABE,Yukio SAITO,Daisuke FUJIOKA,Takamitsu NAKAMURA,Junei OBATA,Yoshinobu KITTA,Toshiaki YANO,Kenichi KAWABATA,Kazuhiro WATANABE,Hideto MISHINA,Sadahiro ITO,Kiyotaka KUGIYAMA

    Cardiovascular research   85 ( 4 )   785 - 795   2010.3

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    Language:English  

  • Avoiding the effect of linked genes is crucial to elucidate the role of Apcs in autoimmunity. Reviewed Major achievement

    Toshio TAMAOKI,Hideo TEZUKA,Yoshiie OKADA,Sadahiro ITO,Hiroki SHIMURA,Toyoshi ENDO,Yukio OZAKI,Shigenobu KANBA,MAEDA Shuichiro

    NATURE MEDICINE   11 ( 1 )   11 - 13   2005.1

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    Language:English  

  • Deposition of transthyretin amyloid is not accelerated by the same amyloid in vivo. Reviewed Major achievement

    Wei L,KAWANO Hiroo,Xiaoying Fu,Dan Cui,Sadahiro ITO,Ken-ichi Yamamura,Tokuhiro Ishihara,Takahiko Tokuda,Keiichi Higuchi,MAEDA Shuichiro

    AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS   11 ( 2 )   113 - 120   2004.6

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    Language:English  

  • Mice lacking serum amyloid P component do not necessarily develop severe autoimmune disease Reviewed Major achievement

    Makoto SOMA,Toshio TAMAOKI,Hiroo KAWANO,Sadahiro ITO,Mihoko SAKAMOTO,Yoshiie OKADA,Yukio OZAKI,Shigenobu KANBA,Yoshiki HAMADA,Tokuhiro ISHIHARA,Shuichiro MAEDA

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   286   200 - 205   2001.8

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    Language:English  

  • Homozygous serum amyloid P component-deficiency does not enhance regression of AA amyloid deposits. Reviewed Major achievement

    Ikuo Usui,Hiroo Kawano,Sadahiro ITO,Yoshiki HAMADA,Tokuhiro Ishihara,MAEDA Shuichiro

    AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS   8 ( 2 )   101 - 104   2001.6

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    Language:English  

  • Disruption of aldose reductase gene (Akrlbl) causes defect in urinary concentrating ability and divalent cation homeostasis. Reviewed Major achievement

    Kaoru AIDA,Ykinobu IKEGISHI,CHEN Jing,Masato TAWATA,MAEDA Shuichiro,Toshimasa ONAYA,Sadahiro ITO

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   281 - 286   2000.11

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    Language:English  

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Books and Other Publications

  • Mouse Models of Transthyretin Amyloidosis Major achievement

    Sadahiro ITO,MAEDA Shuichiro(-)

    Springer  2009.9 

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    Total pages:360   Responsible for pages:261-   Language:English  

  • 遺伝子改変マウスを用いた家族性アミロイドポリニューロパチー発症の分子機構の解析 Major achievement

    前田 秀一郎,伊藤 禎洋(-)

    金原出版、東京  2005.10 

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    Responsible for pages:68-74-   Language:Japanese  

Presentations

  • Mice Lacking the Glutamate-Cysteine Ligase Modifier Subunit are Susceptible to Myocardial Ischemia-Reperfusion Injury Through Reduction of Mitochondrial Glutathione. Major achievement

    Tsuyoshi KOBAYASHI,Kenichi KAWABATA,Yukio SAITO,Daisuke FUJIOKA,Kazuto NAKAMURA,Toshiaki YANO,Ryota SATO,Kazuhiro WATANABE,Yosuke WATANABE,Junei OBATA,Takamitsu NAKAMURA,Sadahiro ITO,Timothy P DALTON,Kiyotaka KUGIYAMA

    American Heart Association Scientific Sessions 2008  2008.11 

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    Event date: 2008.11

    Language:English   Presentation type:Oral presentation(general)  

    Venue:New Orleans  

  • 遺伝性アルツハイマー病におけるAβアミロイド沈着への血清アミロイドP成分の関与に関する研究 Major achievement

    ワティヘンニ,瓦林 毅,河西あゆみ,伊藤 禎洋,松原悦朗,東海林幹夫,前田 秀一郎

    第28回日本分子生物学会年会  2005.12 

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    Event date: 2005.12

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:福岡  

  • 血清アミロイドP成分(SAP)の欠損は、自己免疫疾患を惹起しない Major achievement

    伊藤 禎洋,手塚 英夫,岡田 芳家,玉置 寿男,大森弘子,坂本美穂子,尾崎 由基男,神庭 重信,山村研一,前田 秀一郎

    第26回日本分子生物学会年会  2003.12 

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    Event date: 2003.12

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:神戸  

  • 血清アミロイドP成分(SAP)の欠損は、自己免疫疾患を惹起しない Major achievement

    伊藤 禎洋

    日本分子生物学会  2003.10 

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    Event date: 2003.10

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:兵庫県神戸市  

  • “Possible role of transthyretin in PCB-induced alterations of thyroid hormone homeostasis in mice" Major achievement

    西村 典子,米元 純三,宮原 裕一,横井,竹内,伊藤 禎洋,前田 秀一郎,遠山千春

    健康時と罹患時におけるトランスサイレチンの役割に関する第1回国際学術会議  2002.4 

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    Event date: 2002.4

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:フランス ストラスブル  

Teaching Experience (On-campus)

  • 実験医学

    2020Year  Type of subject:Professional education (undergraduate)

  • 実験医学

    2018Year  Type of subject:Professional education (undergraduate)

  • 平成30年度後期チュートリアルグループ学習

    2018Year  Type of subject:Professional education (undergraduate)

  • 平成30年度前期チュートリアルグループ学習

    2018Year  Type of subject:Professional education (undergraduate)

  • 実験医学

    2017Year  Type of subject:Professional education (undergraduate)

  • 平成29年度後期チュートリアルグループ学習

    2017Year  Type of subject:Professional education (undergraduate)

  • 平成29年度前期チュートリアルグループ学習

    2017Year  Type of subject:Professional education (undergraduate)

  • 実験医学

    2016Year  Type of subject:Professional education (undergraduate)

    胚操作技術
      1. 胚培養、仮親への移植、キメラ個体作出などの胚操作技術を理解できる
      2. 発生工学の基盤となる胚幹細胞とiPS細胞(人工万能細胞)の現状と今後の
    見通しを説明できる。

  • 実験医学

    2016Year  Type of subject:Professional education (undergraduate)

    胚操作技術
      1. 胚培養、仮親への移植、キメラ個体作出などの胚操作技術を理解できる
      2. 発生工学の基盤となる胚幹細胞とiPS細胞(人工万能細胞)の現状と今後の
    見通しを説明できる

  • 実験医学

    2015Year  Type of subject:Professional education (undergraduate)

    胚操作技術
      1. 胚培養、仮親への移植、キメラ個体作出などの胚操作技術を理解できる
      2. 発生工学の基盤となる胚幹細胞とiPS細胞(人工万能細胞)の現状と今後の
    見通しを説明できる

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Professional Memberships

  • 日本実験動物学会

    2017.4

  • 日本ゲノム編集学会

    2016.8

  • 日本分子生物学会

    2006.2

  • 日本生化学会

    2006.2

  • The Japanese Biochemical Society

  • The Molecular Biology Society of Japan

  • 日本分子生物学会

  • 日本生化学会

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