Organization
Graduate Faculty of Interdisciplinary Research Faculty of Medicine Basic Science for Clinical Medicine (Immunology) Assistant Professor
Title
Assistant Professor
TRAN NGUYEN QUOC VUONG
Education
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University of Yamanashi Department of Health Sciences Life Sciences
2015.4 - 2018.3
Country： Japan
Course： Doctor course
Degree
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Ph.D (Life Sciences) ( 2018.3 University of Yamanashi )
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Medical Doctor ( 2012.10 University of Medicine and Pharmacy, Ho Chi Minh City )
Research Areas
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Life Science / Immunology
Research Interests
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Bioinformatic analysis in allergic disease, mast cells, immunology, circadian clock
Research Projects
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アレルギー疾患における生体内マスト細胞の量・空間・時間的解 析
Grant number：22K20883 2022.9
University of Yamanashi
Authorship：Principal investigator Grant type：Competitive Type of fund：：Funded research
Papers
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IL-33 Sensitizes Mast Cells to Piezo1 Stimulation Leading to Degranulation Reviewed
Yoshiaki Kobayashi, Kent Sakai, Nguyen Quoc Vuong Tran, Kayoko Ishimaru, Takuya Sato, Yuki Nakamura, Daiki Nakagomi, Satoshi Tanaka, Schuichi Koizumi, Atsuhito Nakao
Allergy 2024.11
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Transcriptomic evidence for T cell-fibroblast-keratinocyte axis via IL-13-periostin-integrin in atopic dermatitis Reviewed Major achievement
Nguyen Quoc Vuong Tran, Yoshiaki Kobayashi, Yuki Nakamura, Kayoko Ishimaru, Kenji Izuhara, Atsuhito Nakao
Allergy 2024.10
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Minh-Khang Le, Nguyen Quoc Vuong Tran, Phuc-Tan Nguyen, Thuy-An Nguyen, Atsuhito Nakao, Tetsuo Kondo
Journal of Neuropathology & Experimental Neurology 2024 ( nlae055 ) 2024.7
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Severe asthmatic airways have distinct circadian clock gene expression pattern associated with WNT signaling Reviewed Major achievement
Nguyen Quoc Vuong Tran, Minh Khang Le, Yuki Nakamura, Atsuhito Nakao
Clinical and Translational Allergy 14 ( 7 ) e12379 2024.6
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A highly selective KIT inhibitor MOD000001 suppresses IgE-mediated mast cell activation Reviewed
Yuki Nakamura, Takeo Urakami, Kayoko Ishimaru, Nguyen Quoc Vuong Tran, Takafumi Shimizu, William Sinko, Taisuke Takahashi, Sivapriya Marappan, Kishore Narayanan, Ramulu Poddutoori, Yoh Terada, Atsuhito Nakao
Journal of Allergy and Clinical Immunology: Global 3 ( 3 ) 100249 2024.4
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喘息患者気道ではマスト細胞が増加し活性化が亢進している Invited
Nguyen Quoc Vuong Tran, 中尾篤人
臨床免疫・アレルギー科 81 ( 3 ) 262 - 268 2024.3
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Deficiency of BMAL1 promotes ROS generation and enhances IgE-dependent degranulation in mast cells Reviewed
Yuka Nagasaka, Yuki Nakamura, Nguyen Quoc Vuong Tran, Yoshiaki Kobayashi, Nobuhiro Nakano, Atsuhito Nakao
Biochemical and Biophysical Research Communications 2024.1
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A link between KIT expression, mast cell abundance and activity, and Th2‐high endotype in asthmatic airways Reviewed Major achievement
Nguyen Quoc Vuong Tran, Minh‐Khang Le, Yuki Nakamura, Tetsuo Kondo, Atsuhito Nakao
Allergy 2023.11
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Thuy-An Nguyen, Minh-Khang Le, Phuc-Tan Nguyen, Nguyen Quoc Vuong Tran, Tetsuo Kondo, Atsuhito Nakao
Translational Lung Cancer Research 12 ( 10 ) 1972 - 1986 2023.10
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Ethyl Caffeate Can Inhibit Aryl Hydrocarbon Receptor (AhR) Signaling and AhR-Mediated Potentiation of Mast Cell Activation
Phuc-Tan Nguyen, Yuki Nakamura, Nguyen Quoc Vuong Tran, Kayoko Ishimaru, Thuy-An Nguyen, Yoshiaki Kobayashi, Fumie Watanabe-Saito, Tohru Okuda, Nobuhiro Nakano, Atsuhito Nakao
International Journal of Molecular Sciences 24 ( 12 ) 9997 2023.6
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Association of Circadian Clock Gene Expression with Pediatric/Adolescent Asthma and Its Comorbidities Reviewed Major achievement
Nguyen Quoc Vuong Tran, Minh-Khang Le, Thuy-An Nguyen, Tetsuo Kondo, Atsuhito Nakao
International Journal of Molecular Sciences 24 ( 8 ) 7477 2023.4( ISSN：1422-0067 eISSN：1422-0067 )
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Association between DNA methylation in cord blood and maternal smoking: The Hokkaido Study on Environment and Children’s Health Reviewed
Kunio Miyake, Akio Kawaguchi, Ryu Miura, Sachiko Kobayashi, Nguyen Quoc Vuong Tran, Sumitaka Kobayashi, Chihiro Miyashita, Atsuko Araki, Takeo Kubota, Zentaro Yamagata, Reiko Kishi
Scientific reports 8 ( 1 ) 1 - 14 2018.4
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Neurodevelopmental disorders and environmental toxicants: epigenetics as an underlying mechanism Reviewed
Nguyen Quoc Vuong Tran, Kunio Miyake
International journal of genomics 2017 2017.10
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Pre-treatment with amitriptyline causes epigenetic up-regulation of neuroprotection-associated genes and has anti-apoptotic effects in mouse neuronal cells
Nguyen Quoc Vuong Tran, An Nghia Nguyen, Kyoko Takabe, Zentaro Yamagata, Kunio Miyake
Neurotoxicology and teratology 62 1 - 12 2017.7
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Prader-Willi syndrome: the disease that opened up epigenomic-based preemptive medicine Reviewed
Takeo Kubota; Kunio Miyake; Natsuyo Hariya; Tran Nguyen Quoc, Vuong; Kazuki Mochizuki
Diseases 4 ( 1 ) 1 - 15 2016.3
Books and Other Publications
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Pharmacoepigenetics - Chapter: Pharmacoepigenetics and Toxicoepigenetics in Neurodevelopmental Disorders
Nguyen Quoc Vuong Tran, Kunio Miyake（ Role： Joint Work711-719）
Academic Press 2019.1
Presentations
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A link between KIT expression, mast cell abundance and activity, and Th2-high endotype in asthmatic airways Invited International conference Major achievement
Tran Nguyen Quoc Vuong
The 73rd Annual Meeting of the Japanese Society of Allergology 2024.10 Japanese Society of Allergology
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Unique circadian clock gene expression pattern linked to WNT signaling in severe asthmatic airways International conference Major achievement
Nguyen Quoc Vuong Tran, Yuki Nakamura, Atsuhito Nakao
第73回日本アレルギー学会学術大会 2024.10 Japanese Society of Allergology
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Ethyl caffeate can antagonize the aryl hydrocarbon receptor signaling, which is associated with its anti-allergic property International conference
Nguyen Phuc Tan, Nakamura Y, Ishimaru K, Nguyen Thuy An, Tran Nguyen Quoc Vuong, Okuda T, Nakao
2023.10
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MOD000001, a Novel Highly Selective and Orally Available KIT Inhibitor, Suppresses Passive Cutaneous Anaphylactic (PCA) Reaction and Food Allergy in Mice International conference
Atsuhito Nakao, Takeo Urakami, Yuki Nakamura, Kayoko Ishimaru, Vuong Tran, Taisuke Takahashi, Takafumi Shimizu, William Sinko, Venkateshwar Gummadi, Amit Dhudashiya, Ravikrishna Babu , Yoh Terada
American Academy of Allergy, Asthma & Immunology Annual Meeting 2023.2
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Identification of MOD000001, A Novel Highly Selective and Orally Available KIT Inhibitor Designed for Treatment of Mast CellAssociated Disorders
Takeo Urakami, Taisuke Takahashi, Takafumi Shimizu, William Sinko, Yuki Nakamura, Kayoko Ishimaru, Vuong Tran, Ramulu Poddutoori, Kishore Narayanan, Sivapriya Marappan, Atsuhito Nakao, Yoh Terada
American Academy of Allergy, Asthma & Immunology Annual Meeting 2023.2
Awards
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山梨大学医学会若手研究者表彰奨学金 Major achievement
2024.5 山梨大学医学会