Updated on 2024/05/01

写真a

 
Manabu Niimi
 
Organization
Graduate Faculty of Interdisciplinary Research Faculty of Medicine Basic Science for Clinical Medicine (Molecular Pathology) Assistant Professor
Title
Assistant Professor
External link

Research History

  • University of Yamanashi   Department of Molecular Pathology, Faculty of Medicine   Assistant professor

    2021.2

  • University of Yamanashi   Department of Molecular Pathology, Faculty of Medicine   Assistant professor

    2019.3 - 2021.1

  • University of Yamanashi   Department of Molecular Pathology, Faculty of Medicine   Assistant Professor

    2017.9 - 2019.2

  • University of Yamanashi   Department of Molecular Pathology, Faculty of Medicine   Research Assistant Professor

    2012.9 - 2017.8

  • Otsuka Pharmaceutical Co., Ltd.   Pharmaceutical Division   Research Scientist

    2007.10 - 2012.8

  • Japan Immunoresearch Laboratories Co., Ltd.   Diagnostic Division   Chief

    2003.6 - 2007.10

  • Japan Immunoresearch Laboratories Co., Ltd.   Diagnostic Division

    1996.4 - 2003.6

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Education

  • University of Yamanashi   Interdisciplinary Graduate School of Medicine and Engineering   Department of Human Environment Medical Engineering

    - 2014.3

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    Country: Japan

    Course: Doctor course

  • Niigata University   Graduate School of Science   Department of Biology

    - 1996.3

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    Country: Japan

    Course: Master course

  • Niigata University   Faculty of Science   Department of Biology

    - 1994.3

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    Country: Japan

Degree

  • Ph. D. ( 2014.3   University of Yamanashi )

  • MSc ( 1996.3   Niigata University )

Other careers

  • Teikyo Yamanashi School of Nursing, Adjunct Lecturer (2021/09 - )

Research Areas

  • Life Science / Pathological biochemistry  / Lipoprotein metabolism, Dyslipidemia, Hyperlipidemia

  • Life Science / Experimental pathology  / Vascular pathology, Arteriosclerosis, Atherosclerosis

Research Interests

  • Arteriosclerosis

  • Atherosclerosis

  • Lipoprotein metabolism

  • Dyslipidemia

  • Hyperlipidemia

  • Knockout rabbits

  • Transgenic rabbits

Subject of research

  • Molecular pathophysiology of atherosclerotic diseases

Research Projects

  • Effects of ANGPTLs on dyslipidemia and atherosclerosis: analysis using gene-modified rabbits

    Grant number:23K08000  2023.4 - 2027.3

    Japan Society for the Promotion of Science (JSPS)  Grants-in-Aid for Scientific Research (KAKENHI)  Grant-in-Aid for Scientific Research (C)

    Kazutoshi Nishijima, Jianglin Fan, Manabu Niimi, Shuji Kitajima, Fumikazu Matsuhisa

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    Authorship:Coinvestigator(s)  Grant type:Competitive  Type of fund::Science research expense

  • Elucidation of the pathogenesis of aortic disease and organ damage by angioscopy using a genetically modified rabbit model

    Grant number:23K08267  2023.4 - 2026.3

    Japan Society for the Promotion of Science (JSPS)  Grants-in-Aid for Scientific Research (KAKENHI)  Grant-in-Aid for Scientific Research (C)

    Akira Sato, Jianglin Fan, Manabu Niimi

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    Authorship:Coinvestigator(s)  Grant type:Competitive  Type of fund::Science research expense

  • Elucidation of IDOL inhibition effects on hyperlipidemia and atherosclerosis using KO rabbits

    Grant number:23K06480  2023.4 - 2026.3

    Japan Society for the Promotion of Science (JSPS)  Grants-in-Aid for Scientific Research (KAKENHI)  Grant-in-Aid for Scientific Research (C)

    Jianglin Fan, Manabu Niimi, Xiangming Tang

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    Authorship:Coinvestigator(s)  Grant type:Competitive  Type of fund::Science research expense

  • Functions of apo A-V in atherosclerosis: a study of knockout rabbit model

    Grant number:20K08858  2020.4 - 2023.3

    Japan Society for the Promotion of Science (JSPS)  Grants-in-Aid for Scientific Research (KAKENHI)  Grant-in-Aid for Scientific Research (C)

    Manabu Niimi, Fumikazu Matsuhisa, Yajie Chen

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    Authorship:Principal investigator  Grant type:Competitive  Type of fund::Science research expense

  • Function of apolipoprotein E: insight from ApoE-deficient rabbit study

    Grant number:17K08783  2017.4 - 2020.3

    Japan Society for the Promotion of Science (JSPS)  Grants-in-Aid for Scientific Research (KAKENHI)  Grant-in-Aid for Scientific Research (C)

    Manabu Niimi

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    Authorship:Principal investigator  Grant type:Competitive  Type of fund::Science research expense

  • Role of lipoprotein lipase on exercise effects

    Grant number:16K08607  2016.10 - 2019.3

    Japan Society for the Promotion of Science (JSPS)  Grants-in-Aid for Scientific Research (KAKENHI)  Grant-in-Aid for Scientific Research (C)

    Kazutoshi Nishijima, Yuichiro Nishida, Manabu Niimi

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    Authorship:Coinvestigator(s)  Grant type:Competitive  Type of fund::Science research expense

  • Elucidation of roles of MMP-1 in atherosclerosis and plaque rupture using transgenic rabbits

    Grant number:26460486  2014.4 - 2017.3

    Japan Society for the Promotion of Science (JSPS)  Grants-in-Aid for Scientific Research (KAKENHI)  Grant-in-Aid for Scientific Research (C)

    Manabu Niimi, Kazutoshi Nishijima, Jianglin Fan

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    Authorship:Principal investigator  Grant type:Competitive  Type of fund::Science research expense

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Papers

  • Gut bacteria exacerbates TNBS-induced colitis and kidney injury through oxidative stress. Reviewed

    Sui Y, Jiang R, Niimi M, Wang X, Xu Y, Zhang Y, Shi Z, Suda M, Mao Z, Fan J, Yao J.

    Redox Biol.   72   103140   2024.3( ISSN:2213-2317 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER  

    DOI: 10.1016/j.redox.2024.103140

  • A Simple Telemetry Sensor System for Monitoring Body Temperature in Rabbits-A Brief Report Reviewed

    Chen Y, Niimi M, Zhang L, Tang X, Lu J, Fan J.

    Animals.   13 ( 10 )   1677   2023.5( ISSN:2076-2615 )

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ani13101677

  • Development of dietary thiol antioxidant via reductive modification of whey protein and its application in the treatment of ischemic kidney injury. Reviewed

    Sui Y, Jiang R, Niimi M, Hong J, Yan Q, Shi Z, Yao J.

    Antioxidants.   12 ( 1 )   193   2023.1( ISSN:2076-3921 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:MDPI  

    DOI: 10.3390/antiox12010193

  • The Combined Administration of Vitamin C and Copper Induces a Systemic Oxidative Stress and Kidney Injury. Reviewed

    Jiang R, Sui Y, Hong J, Niimi M, Yan Q, Shi Z, Yao J.

    Biomolecules.   13 ( 1 )   143   2023.1( ISSN:2218-273X )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:MDPI  

    DOI: 10.3390/biom13010143

  • Examining atherosclerotic lesions in three dimensions at the nanometer scale with cryo-FIB-SEM. Reviewed

    Capua-Shenkar J, Varsano N, Itzhak NR, Kaplan-Ashiri I, Rechav K, Jin X, Niimi M, Fan J, Kruth HS, Addadi L.

    Proc Natl Acad Sci U S A.   119 ( 34 )   e2205475119   2022.8( ISSN:0027-8424 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:NATL ACAD SCIENCES  

    DOI: 10.1073/pnas.2205475119

  • Is apoCIII-Lowering A Double-Edged Sword? Reviewed

    Tang X, Zhou H, Yan H, Niimi M, Fan J.

    J Atheroscler Thromb.   29 ( 7 )   1117 - 1124   2022.7( ISSN:1340-3478 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:JAPAN ATHEROSCLEROSIS SOC  

    DOI: 10.5551/jat.LE002

  • Pathological Investigations of Intracranial Atherosclerosis Using Multiple Hypercholesterolemic Rabbit Models. Reviewed

    Tang X, Niimi M, Zhou H, Chen L, Chen Y, Yan H, Shiomi M, Fan J.

    Front Endocrinol.   13   834207   2022.4( ISSN:1664-2392 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:FRONTIERS MEDIA SA  

    DOI: 10.3389/fendo.2022.834207

  • Tanshinone IIA Stimulates Cystathionine γ-Lyase Expression and Protects Endothelial Cells from Oxidative Injury. Reviewed

    Yan Q, Mao Z, Hong J, Gao K, Niimi M, Mitsui T, Yao J.

    Antioxidants.   10 ( 7 )   1007   2021.6( ISSN:2076-3921 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:MDPI  

    DOI: 10.3390/antiox10071007

  • Strategies for Highly Efficient Rabbit Sperm Cryopreservation. Reviewed

    Nishijima K, Kitajima S, Matsuhisa F, Niimi M, Wang CC, Fan J.

    Animals.   11 ( 5 )   1220   2021.4( ISSN:2076-2615 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:MDPI  

    DOI: 10.3390/ani11051220

  • Endothelial lipase exerts its anti-atherogenic effect through increased catabolism of β-VLDLs. Reviewed

    Yan H, Niimi M, Wang C, Chen Y, Zhou H, Matsuhida F, Nishijima K, Kitajima S, Nakajima K, Murakami M, Zhang J, Chen YE, Fan J.

    J Atheroscler Thromb.   28 ( 2 )   157 - 168   2021.2( ISSN:1340-3478 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:JAPAN ATHEROSCLEROSIS SOC  

    DOI: 10.5551/jat.55244

  • Isolation and analysis of plasma lipoproteins by ultracentrifugation. Reviewed

    Niimi M, Yan H, Chen YJ, Wang Y, Fan J.

    J Vis Exp.   167   e61790   2021.1( ISSN:1940-087X )

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:JOURNAL OF VISUALIZED EXPERIMENTS  

    DOI: 10.3791/61790

  • Hyperlipidemic rabbit models for anti-atherosclerotic drug development. Reviewed

    Niimi M, Chen YJ, Yan H, Wang Y, Koike T, Fan J.

    Appl Sci.   10 ( 23 )   8681   2020.12( ISSN:2076-3417 )

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:MDPI  

    DOI: 10.3390/app10238681

  • Apolipoprotein CIII deficiency protects against atherosclerosis in knock-out rabbits. Reviewed

    Yan H, Niimi M, Matsuhisa F, Zhou H, Kitajima S, Chen YJ, Wang C, Yang X, Yao J, Yang D, Zhang J, Murakami M, Nakajima K, Wang Y, Liu E, Liang J, Chen YE, Fan J.

    Arterioscler Thromb Vasc Biol.   40 ( 9 )   2095 - 2107   2020.9( ISSN:1079-5642 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:LIPPINCOTT WILLIAMS & WILKINS  

    DOI: 10.1161/ATVBAHA.120.314368

  • Sex hormones affect endothelial lipase-mediated lipid metabolism and atherosclerosis. Reviewed

    Wang C, Niimi M, Kitajima S, Matsuhisa F, Yan H, Dong S, Liang J, Fan J.

    Lipids Health Dis.   18 ( 1 )   226   2019.12( ISSN:1476-511X )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:BMC  

    DOI: 10.1186/s12944-019-1175-4

  • Macrophage-derived matrix metalloproteinase-1 enhances aortic aneurysm formation in transgenic rabbits. Reviewed

    Niimi M, Nishijima K, Kitajima S, Matsuhisa F, Satoh K, Yamazaki H, Zhang J, Chen YE, Fan J.

    J Biomed Res.   33 ( 4 )   271 - 279   2019.7( ISSN:1674-8301 )

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:NANJING MEDICAL UNIV  

    DOI: 10.7555/JBR.33.20180097

  • Treatment of atherosclerosis by traditional Chinese medicine: Questions and quandaries. Reviewed

    Wang C, Niimi M, Watanabe T, Wang Y, Liang J, Fan J.

    ATHEROSCLEROSIS   277   136 - 144   2018.8( ISSN:0021-9150 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER  

    DOI: 10.1016/j.atherosclerosis.2018.08.039

  • Detection of potential new biomarkers of atherosclerosis by probe electrospray ionization mass spectrometry. Reviewed

    Johno H, Yoshimira K, Mori Y, Kimura T, Niimi M, Yamada M, Tanigawa T, Fan J, Takeda S

    Metabolomics   14 ( 4 )   38   2018.4( ISSN:1573-3882 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:SPRINGER  

    DOI: 10.1007/s11306-018-1334-z

  • Principles and Applications of Rabbit Models for Atherosclerosis Research. Reviewed

    Fan J, Chen Y, Yan H, Niimi M, Wang Y, Liang J.

    Journal of Atherosclerosis and Thrombosis   25 ( 3 )   213 - 220   2018.3( ISSN:1340-3478 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:JAPAN ATHEROSCLEROSIS SOC  

    DOI: 10.5551/jat.RV17018

  • Glutathione inhibits antibody and complement-mediated immunologic cell injury via multiple mechanisms. Reviewed

    Zhang Z, Zhang X, Fang X, Niimi M, Huang Y, Piao H, Gao S, Fan J, Yao J.

    Redox Biology   12   571 - 581   2017.8( ISSN:2213-2317 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER  

    DOI: 10.1016/j.redox.2017.03.030

  • Comparative studies of three cholesteryl ester transfer proteins and their interactions with known inhibitors. Reviewed

    Wang Z, Niimi M, Ding Q, Liu Z, Wang L, Zhang J, Xu J, Fan J.

    PLoS One   12 ( 8 )   e0180772   2017.8( ISSN:1932-6203 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:PUBLIC LIBRARY SCIENCE  

    DOI: 10.1371/journal.pone.0180772

  • Increased hepatic expression of endothelial lipase inhibits cholesterol diet-induced hypercholesterolemia and atherosclerosis in transgenic rabbits. Reviewed

    Wang C, Nishijima K, Kitajima S, Niimi M, Yan H, Chen Y, Ning B, Matsuhisa F, Liu E, Zhang J, Chen YE, Fan J.

    Arterioscler Thromb Vasc Biol.   37 ( 7 )   1282 - 1289   2017.7( ISSN:1079-5642 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:LIPPINCOTT WILLIAMS & WILKINS  

    DOI: 10.1161/ATVBAHA.117.309139

  • Deficiency of cholesteryl ester transfer protein protects against atherosclerosis in rabbits. Reviewed

    Zhang J, Niimi M, Yang D, Liang J, Xu J, Kimura T, Mattew AV, Guo Y, Fan Y, Zhu T, Song J, Ackermann R, Koike Y, Schwendeman A, Lai L, Pennathur S, Garcia-Barrio M, Fan J, Chen YE.

    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY   37 ( 6 )   1068 - 1075   2017.6( ISSN:1079-5642 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:LIPPINCOTT WILLIAMS & WILKINS  

    DOI: 10.1161/ATVBAHA.117.309114

  • Suramin inhibits antibody binding to cell surface antigens and disrupts complement-mediated mesangial cell lysis. Reviewed

    JOURNAL OF PHARMACOLOGICAL SCIENCES   132 ( 4 )   224 - 234   2016.12( ISSN:1347-8613 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:JAPANESE PHARMACOLOGICAL SOC  

    DOI: 10.1016/j.jphs.2016.03.011

  • Hyperlipidemia-associated gene variations and expression patterns revealed by whole-genome and transcriptome sequencing of rabbit models. Reviewed

    Wang Z, Zhang J, Li H, Li J, Niimi M, Ding G, Chen H, Xu J, Zhang H, Xu Z, Dai Y, Gui T, Li S, Liu Z, Wu S, Cao M, Zhou L, Lu X, Wang J, Yang J, Fu Y, Yang D, Song J, Zhu T, Li S, Ning B, Wang Z, Koike T, Shiomi M, Liu E, Chen L, Fan J, Chen YE, Li Y.

    Scientific Reports   6   26942   2016.6( ISSN:2045-2322 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:NATURE PUBLISHING  

    DOI: 10.1038/srep26942

  • Angiotensin II destabilizes coronary plaques in Watanabe heritable hyperlipidemic rabbits. Reviewed

    Li S, Wang YN, Niimi M, Ning B, Chen Y, Kang D, Waqar AB, Wang Z, Yu Q, Liu E, Zhang J, Shiomi M, Chen YE, Fan J.

    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY   36 ( 5 )   810 - 816   2016.5( ISSN:1079-5642 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:LIPPINCOTT WILLIAMS & WILKINS  

    DOI: 10.1161/ATVBAHA.115.306871

  • ApoE knockout rabbits: A novel model for the study of human hyperlipidemia. Reviewed

    Niimi M, Yang D, Kitajima S, Ning B, Wang C, Li S, Liu E, Zhang J, Chen YE, Fan J.

    ATHEROSCLEROSIS   245   187 - 193   2016.2( ISSN:0021-9150 )

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER  

    DOI: 10.1016/j.atherosclerosis.2015.12.002

  • Bisphenol A exposure induces metabolic disorders and enhances atherosclerosis in hyperlipidemic rabbits. Reviewed

    Fang C, Ning B, Waqar AB, Niimi M, Li S, Satoh K, Shiomi M, Ye T, Dong S, Fan J.

    JOURNAL OF APPLIED TOXICOLOGY   35 ( 9 )   1058 - 1070   2015.9( ISSN:0260-437X )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:WILEY  

    DOI: 10.1002/jat.3103

  • Dietary cholesterol atherogenic changes in juvenile rabbits. Reviewed

    Keyamura Y, Nagano C, Kohashi M, Niimi M, Nozako M, Koyama T, Itabe H, Yoshikawa T.

    BIOLOGICAL & PHARMACEUTICAL BULLETIN   38 ( 5 )   785 - 788   2015.5( ISSN:0918-6158 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:PHARMACEUTICAL SOC JAPAN  

    DOI: 10.1248/bpb.b14-00775

  • Bisphenol A exposure enhances atherosclerosis in WHHL rabbits. Reviewed

    Fang C, Ning B, Waqar AB, Niimi M, Li S, Satoh K, Shiomi M, Ye T, Dong S, Fan J.

    PLoS One.   9 ( 10 )   e110977   2014.10( ISSN:1932-6203 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:PUBLIC LIBRARY SCIENCE  

    DOI: 10.1371/journal.pone.0110977

  • Probucol suppresses macrophage infiltration and MMP expression in atherosclerotic plaques of WHHL rabbits. Reviewed

    Li S, Liang J, Niimi M, Waqar AB, Kang D, Koike T, Wang Y, Shiomi M, Fan J.

    J Atheroscler Thromb.   21 ( 7 )   648 - 658   2014.7( ISSN:1340-3478 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:JAPAN ATHEROSCLEROSIS SOC  

    DOI: 10.5551/jat.21600

  • Add-on effect of probucol in atherosclerotic, cholesterol-fed rabbits treated with atorvastatin. Reviewed

    Keyamura Y, Nagano C, Kohashi M, Niimi M, Nozako M, Koyama T, Yasufuku R, Imaizumi A, Itabe H, Yoshikawa T.

    PLoS One.   9 ( 5 )   e96929   2014.5( ISSN:1932-6203 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:PUBLIC LIBRARY SCIENCE  

    DOI: 10.1371/journal.pone.0096929

  • Probucol inhibits the initiation of atherosclerosis in cholesterol-fed rabbits. Reviewed

    Niimi M, Keyamura Y, Nozako M, Koyama T, Kohashi M, Yasufuku R, Yoshikawa T, Fan J.

    Lipids Health Dis.   12   166   2013.11( ISSN:1476-511X )

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:BMC  

    DOI: 10.1186/1476-511X-12-166

  • Human Apolipoprotein A-II Protects Against Diet-Induced Atherosclerosis in Transgenic Rabbits. Reviewed

    Wang Y, Niimi M, Nishijima K, Waqar AB, Yu Y, Koike T, Kitajima S, Liu E, Inoue T, Kohashi M, Keyamura Y, Yoshikawa T, Zhang J, Ma L, Zha X, Watanabe T, Asada Y, Chen YE, Fan J.

    Arterioscler Thromb Vasc Biol.   33 ( 2 )   224 - 231   2013.2( ISSN:1079-5642 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:LIPPINCOTT WILLIAMS & WILKINS  

    DOI: 10.1161/ATVBAHA.112.300445

  • Cilostazol inhibits accumulation of triglyceride in aorta and platelet aggregation in cholesterol-fed rabbits. Reviewed

    Ito H, Uehara K, Matsumoto Y, Hashimoto A, Nagano C, Niimi M, Miyakoda G, Nagano K.

    PLoS One.   7   e3937   2012.6( ISSN:1932-6203 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:PUBLIC LIBRARY SCIENCE  

    DOI: 10.1371/journal.pone.0039374

  • Cholesterol efflux from J774 macrophages and Fu5AH hepatoma cells to serum is preserved in CETP-deficient patients. Reviewed

    Miwa K, Inazu A, Kawashiri M, Nohara A, Higashikata T, Kobayashi J, Koizumi J, Nakajima K, Nakano T, Niimi M, Mabuchi H, Yamagishi M.

    Clin Chim Acta.   402   19 - 24   2009.4( ISSN:0009-8981 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER  

    DOI: 10.1016/j.cca.2008.12.012

  • Detection of apolipoproteins B-48 and B-100 carrying particles in lipoprotein fractions extracted from human aortic atherosclerotic plaques in sudden cardiac death cases. Reviewed

    Nakano T, Nakajima K, Niimi M, Fujita MQ, Nakajima Y, Takeichi S, Kinoshita M, Matsushima T, Teramoto T, Tanaka A.

    CLINICA CHIMICA ACTA   390   38 - 43   2008.4( ISSN:0009-8981 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER  

    DOI: 10.1016/j.cca.2007.12.012

  • Decreased post-prandial triglyceride response and diminished remnant lipoprotein formation in cholesteryl ester transfer protein (CETP) deficiency. Reviewed

    Inazu A, Nakajima K, Nakano T, Niimi M, Kawashiri MA, Nohara A, Kobayashi J, Mabuchi H.

    Atherosclerosis.   196   953 - 957   2008.2( ISSN:0021-9150 )

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER  

    DOI: 10.1016/j.atherosclerosis.2007.02.028

  • Evidence for conformational change of fatty acid-binding protein accompanying binding of hydrophobic ligands. Reviewed

    Honma Y, Niimi M, Uchiumi T, Takahashi Y, Odani S.

    J Biochem.   116   1025 - 1029   1994.10( ISSN:0021-924X )

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:OXFORD UNIV PRESS  

    DOI: 10.1093/oxfordjournals.jbchem.a124623

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Books and Other Publications

  • Atherosclerosis: Methods and Protocols

    Fan J, Niimi M, Chen Y, Suzuki R, Liu E.( Role: Joint WorkChapter 25: Use of Rabbit Models to Study Atherosclerosis)

    Springer  2022.3   ISBN:978-1-0716-1923-0

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    Responsible for pages:413-431   Language:English   Book type:Scholarly book

Presentations

  • Pathological investigations of intracranial atherosclerosis using multiple hypercholesterolemic rabbit models. International conference

    Tang X, Niimi M, Zhou H, Chen L, Chen Y, Yan H, Shiomi M, Fan J.

    The International Conference on Animal Models for Cardiovascular Disease 2023  2023.7 

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    Event date: 2023.7

    Language:English   Presentation type:Poster presentation  

    Venue:Nirasaki, Japan (Chateraise Hotel Nirasaki no Mori)  

  • Hyperlipidemic rabbit models for the study of atherosclerotic disease. Invited International conference

    Niimi M, Fan J.

    The International Conference on Animal Models for Cardiovascular Disease 2023  2023.7 

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    Event date: 2023.7

    Language:English   Presentation type:Oral presentation(invited, special)  

    Venue:Nirasaki, Japan (Chateraise Hotel Nirasaki no Mori)  

  • A novel model for studying hypertriglyceridemia: Apo A-V knockout rabbits

    Niimi M, Matsuhisa F, Kitajima S, Fan J.

    The 55th Annual Scientific Meeting of the Japanese Atherosclerosis Society  2023.7 

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    Event date: 2023.7

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Utsunomiya, Japan (Light Cube Utsunomiya)  

  • A novel model for studying human triglycerides metabolism: Apo A-V knockout rabbits

    Niimi M, Matsuhisa F, Kitajima S, Fan J.

    The 70th Annual Meeting of the Japanese Association for Laboratory Animal Science  2023.5 

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    Event date: 2023.5

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Tsukuba, Japan (Tsukuba International Congress Center)  

  • Angiotensin II aggravates atherosclerotic lesions and enhances plaque erosion in rabbits. International conference

    Chen Y, Zhu M, Wang Y, Niimi M, Fan J.

    The 4th Japan & China Joint Rabbit Biotechnology Meeting  2023.2 

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    Event date: 2023.2

    Language:English   Presentation type:Oral presentation(general)  

    Venue:Fukushima, Japan (Fukushima Medical University)  

  • ApoE-null chylomicron remnants exacerbate atherosclerosis in rabbits.

    Niimi M, Matsuhisa F, Tang X, Chen L, Chen Y, Yan H, Kitajima S, Fan J.

    The 6th Scientific Meeting of Japan Rabbit Bioscience Association  2023.2 

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    Event date: 2023.2

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:Fukushima, Japan (Fukushima Medical University)  

  • Apolipoprotein CIII deficiency exacerbates diet-induced fatty liver and insulin resistance in knock-out rabbits.

    Tang X, Zhou H, Yan H, Niimi M, Fan J.

    The 6th Scientific Meeting of Japan Rabbit Bioscience Association  2023.2 

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    Event date: 2023.2

    Language:English   Presentation type:Oral presentation(general)  

    Venue:Fukushima, Japan (Fukushima Medical University)  

  • Apolipoprotein CIII Deficiency Protects Against Atherosclerosis in Knockout Rabbits. International conference

    Yan H, Niimi M, Matsuhisa F, Yang X, Zhou H, Kitajima S, Chen Y, Wang C, Zhang J, Liu E, Liang J, Chen YE, Lai L, Fan J.

    The 4th Japan & China Joint Rabbit Biotechnology Meeting  2023.2 

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    Event date: 2023.2

    Language:English   Presentation type:Oral presentation(general)  

    Venue:Fukushima, Japan (Fukushima Medical University)  

  • ApoB48-containing chylomicron remnants exacerbate atherosclerosis

    Niimi M, Tang X, Narita K, Fan J.

    The 54th Annual Scientific Meeting of the Japanese Atherosclerosis Society  2022.7 

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    Event date: 2022.7

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Kurume, Japan (Kurume City Plaza)  

  • Apolipoprotein CIII deficient knock-out rabbits are susceptible to diet-induced fatty liver and insulin resistance.

    Tang X, Zhou H, Yan H, Niimi M, Fan J.

    The 54th Annual Scientific Meeting of the Japanese Atherosclerosis Society  2022.7 

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    Event date: 2022.7

    Language:English   Presentation type:Oral presentation(general)  

    Venue:久留米市(久留米シティプラザ)  

  • Pathological investigations of intracranial atherosclerosis using multiple rabbit models. International conference

    Tang X, Niimi M, Fan J.

    The 19th International Symposium on Atherosclerosis  2021.10 

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    Event date: 2021.10

    Language:English   Presentation type:Poster presentation  

    Venue:Kyoto, Japan (Kyoto International Conference Center)  

  • Apolipoprotein CIII deficiency inhibits cholesterol diet-induced hyperlipidemia and atherosclerosis in knockout rabbits. International conference

    Yan H, Niimi M, Matsuhisa F, Yang X, Zhou H, Kitajima S,Chen Y, Wang C, Yao J, Yang D, Zhang J, Murakami M, Nakajima K, Wang Y, Liu E, Liang J, Lai L, Chen YE, Fan J.

    The 19th International Symposium on Atherosclerosis  2021.10 

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    Event date: 2021.10

    Language:English   Presentation type:Oral presentation(general)  

    Venue:Kyoto, Japan (Kyoto International Conference Center)  

  • Apolipoprotein CIII Deficiency Protects Against Atherosclerosis in Knockout Rabbits.

    Yan H, Niimi M, Matsuhisa F, Zhou F, Kitajima S, Chen Y, Wang C, Yang X, Yang D, Zhang J, Wang Y, Liu E, Liang J, Chen YE, Fan J.

    The 53rd Annual Scientific Meeting of the Japanese Atherosclerosis Society  2021.10 

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    Event date: 2021.10

    Language:English   Presentation type:Oral presentation(invited, special)  

    Venue:Kyoto, Japan (Kyoto International Conference Center)  

  • Pathological analysis of intracranial atherosclerosis in hyperlipidemic rabbits

    Tang X, Niimi M, Fan J.

    The 53rd Annual Scientific Meeting of the Japanese Atherosclerosis Society  2021.10 

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    Event date: 2021.10

    Language:English   Presentation type:Oral presentation(general)  

    Venue:Kyoto, Japan (Kyoto International Conference Center)  

  • Plasma chylomicron-remnants accelerate atherosclerosis: Study of ApoE-deficient rabbits

    Niimi M, Matsuhisa F, Zhou F, Chen Y, Yan H, Kitajima S, Fan J.

    The 53rd Annual Scientific Meeting of the Japanese Atherosclerosis Society  2021.10 

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    Event date: 2021.10

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Kyoto, Japan (Kyoto International Conference Center)  

  • Matrix metalloproteinase and atherosclerotic diseases: Findings from the rabbits model

    Niimi M, Chen Y, Fan J.

    The 53rd Annual Scientific Meeting of the Japanese Atherosclerosis Society  2021.10 

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    Event date: 2021.10

    Language:Japanese   Presentation type:Symposium workshop panel(nominated)  

    Venue:Kyoto, Japan (Kyoto International Conference Center)  

  • Plasma chylomicron-remnants accelerate atherosclerosis in ApoE-deficient rabbits

    Niimi M, Matsuhisa F, Kitajima S, Fan J.

    The 110th Annual Meeting of the Japanese Society of Pathology  2021.4 

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    Event date: 2021.4

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Tokyo, Japan (Keio Plaza Hotel)  

  • Deletion of the apoCIII gene in knockout rabbits attenuates cholesterol diet-induced hyperlipidemia and protects against atherosclerosis. International conference

    Yan H, Niimi M, Zhou H, Matsuhisa F, Kitajima S, Yang C, Chen Y, Murakami M, Nakajima K, Liang J, Zhang J, Chen YE, Yao J, Fan J.

    88th EAS (European Atherosclerosis Society) Congress 2020  2020.10 

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    Event date: 2020.10

    Language:English   Presentation type:Oral presentation(general)  

    Venue:Virtual congress  

  • Endothelial lipase exerts its anti-atherogenic effect through increased catabolism of beta-VLDLs International conference

    Wang C, Niimi M, Yan H, Zhou H, Fan J.

    88th EAS (European Atherosclerosis Society) Congress 2020  2020.10 

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    Event date: 2020.10

    Language:English   Presentation type:Poster presentation  

    Venue:Virtual congress  

  • Apolipoprotein AII: A new role in lipoprotein metabolism and atherosclerosis.

    Fan J, Niimi M, Koike T.

    The 52nd Annual Scientific Meeting of the Japan Atherosclerosis Society  2020.7 

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    Event date: 2020.7

    Language:English   Presentation type:Symposium workshop panel(nominated)  

    Venue:Online Conference  

  • Cholesterol efflux capacity of an amphipathic helical peptide in apolipoprotein B-100

    Niimi M, Saitou F, Kanatani K, Nakajima K.

    The 52nd Annual Scientific Meeting of the Japan Atherosclerosis Society  2020.7 

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    Event date: 2020.7

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Online Conference  

  • Characterization of plasma lipids and lipoprotein metabolism of apoCIII knockout rabbits.

    Yan H, Niimi M, Zhou H, Matsuhisa F, Kitajima S, Chen Y, Zhang J, Chen YE, Fan J.

    The 52nd Annual Scientific Meeting of the Japan Atherosclerosis Society  2020.7 

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    Event date: 2020.7

    Language:English   Presentation type:Poster presentation  

    Venue:Online Conference  

  • Endothelial lipase attenuates cholesterol diet-induced hypercholesterolemia and protects against atherosclerosis in transgenic rabbits. International conference

    Niimi M, Wang C, Yan H, Chen Y, Zhou H, Matsuhisa F, Nishijima K, Kitajima S, Zhang J, Chen YE, Fan J.

    42nd Annual Scientific Meeting of the European Lipoprotein Club (ELC)  2019.9 

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    Event date: 2019.9

    Language:English   Presentation type:Poster presentation  

    Venue:Tutzing, Germany (Evangelische Akademie)  

  • Deletion of the apoCIII gene in knockout rabbits enhances the catabolism of triglyceride-rich lipoproteins and attenuates cholesterol diet-induced hyperlipidemia. International conference

    Yan H, Niimi M, Kitajima S, Zhou H, Matsuhisa F, Chen Y, Zhang J, Chen YE, Fan J.

    8th International Congress on Lipid & Atherosclerosis (ICoLA 2019)  2019.9 

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    Event date: 2019.9

    Language:English   Presentation type:Poster presentation  

    Venue:Seoul, Korea (Conrad Hotel)  

  • Endothelial lipase exerts its anti-atherogenic effect through plasma lipid-lowring effect.

    Niimi M, Yan H, Chen Y, Zhou H, Wang C, Matsuhisa F, Nishijima K, Kitajima S, Fan J.

    The 51st Annual Scientific Meeting of the Japan Atherosclerosis Society  2019.7 

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    Event date: 2019.7

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Kyoto International Conference Center (Kyoto, Japan)  

  • CETP inhibition and atherosclerosis therapy: myth or fact. Invited International conference

    Niimi M, Fan J.

    China-Japan International Conference on Atherosclerosis 2018  2018.8 

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    Event date: 2018.8

    Language:English   Presentation type:Oral presentation(invited, special)  

    Venue:Xi'an, China (Jianguo Hotel Xi'an)  

  • Characterization of apolipoprotein C-III knockout rabbits.

    Yan H, Niimi M, Matsuhisa F, Kitajima S, Chen YE, Fan J.

    The 5th Scientific Meeting of Japan Rabbit Bioscience Association  2018.7 

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    Event date: 2018.7

    Language:English   Presentation type:Oral presentation(general)  

    Venue:Kobe, Japan (Kobe University)  

  • Comparison of cryoprotectants for ultra-rapid vitrification (Cryotop method) in rabbit embryos. International conference

    Matsuhisa F, Akiyoshi T, Matsuo K, Morimoto M, Niimi M, Fan J, Kitajima S.

    7th International Congress on Rabbit Biotechnology 2017  2017.8 

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    Event date: 2017.8

    Language:English   Presentation type:Poster presentation  

    Venue:Yamanashi, Japan (Hotel Kaiji)  

  • Increased hepatic expression of endothelial lipase inhibits cholesterol diet-induced hypercholesterolemia and atherosclerosis in transgenic rabbits. International conference

    Wang C, Nishijima K, Kitajima S, Niimi M, Yan H, Chen Y, Ning B, Matsuhisa F, Liu E, Zhang J, Chen YE, Fan J.

    7th International Congress on Rabbit Biotechnology 2017  2017.8 

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    Event date: 2017.8

    Language:English   Presentation type:Poster presentation  

    Venue:Yamanashi, Japan (Hotel Kaiji)  

  • Macrophage-derived matrix metalloproteinase-1 accelerates aortic aneurysm formation in transgenic rabbits.

    Niimi N, Nishijima K, Kitajima S, Matsuhisa F Satoh K, Yamazaki H, Fan J.

    The 49th Annual Scientific Meeting of the Japan Atherosclerosis Society  2017.7 

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    Event date: 2017.7

    Language:English   Presentation type:Poster presentation  

    Venue:Hiroshima, Japan (Grand Prince Hotel Hiroshima)  

  • Deficiency of CETP protects against atherosclerosis in rabbits

    Kimura T, Niimi M, Zhang J, Chen YE, Fan J.

    The 4th Rabbit Bioscience Association Meeting  2016.8 

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    Event date: 2016.8

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:Saga, Japan (Saga University)  

  • Angiotensin II destabilizes coronary plaques in WHHL rabbits.

    Li S, Wang YN, Niimi M, Ning B, Chen Y, Kang D, Wang Z, Yu Q, Waqar AB, Liu E, Zhang J, Shiomi M, Chen YE, Fan J.

    The 48th Annual Scientific Meeting of the Japan Atherosclerosis Society  2016.7 

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    Event date: 2016.7

    Language:English   Presentation type:Poster presentation  

    Venue:Tokyo, Japan (Keio Plaza Hotel)  

  • Hepatic overexpression of endothelial lipase reduces plasma HDL levels in transgenic rabbits.

    Wang C, Nishijima K, Kitajima S, Niimi N, Ning B, Fan J.

    The 48th Annual Scientific Meeting of the Japan Atherosclerosis Society  2016.7 

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    Event date: 2016.7

    Language:English   Presentation type:Poster presentation  

    Venue:Tokyo, Japan (Keio Plaza Hotel)  

  • A novel model for the study of human atherosclerosis: Apo E knockout rabbits

    Niimi M, Kitajima S, Matsuhisa F, Ning B, Wang C, Yang D, Zhang J, Chen YE, Fan J.

    The 63rd Annual Meeting of Japanese Association for Laboratory Animal Science  2016.5 

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    Event date: 2016.5

    Language:Japanese   Presentation type:Oral presentation(general)  

  • Comparison of cryopreservation devices and solutions in thevitrification of rabbit embryos

    Matsuhisa F, Akiyoshi T, Niimi M, Morimoto M, Fan J, Kitajima S.

    The 63rd Annual Meeting of Japanese Association for Animal Science  2016.5 

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    Event date: 2016.5

    Language:Japanese   Presentation type:Poster presentation  

  • ApoE knockout rabbits: a novel model for the study of human hyperlipidemia.

    Niimi N, Ning B, Wang C, Li S, Zhang J, Chen YE, Fan J.

    The 47th Annual Scientific Meeting of the Japan Atherosclerosis Society  2015.7 

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    Event date: 2015.7

    Language:English   Presentation type:Poster presentation  

  • CETP Deficiency in Rabbits Protects High Fat High Cholesterol Diet Induced Atherosclerosis. International conference

    Zhang J, Xu J, Liang J, Yang D, Guo Y, Zhu T, Song J, Niimi M, Lai L, Fan J, Chen YE.

    Arteriosclerosis, Thrombosis and Vascular Biology/ Peripheral Vascular Disease Scientific Sessions 2015  2015.5 

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    Event date: 2015.5

    Language:English   Presentation type:Poster presentation  

    Venue:San Francisco, USA (Hilton San Francisco Union Square Hotel)  

  • Probucol inhibits the initiation of atherosclerosis in cholesterol-fed rabbits International conference

    Niimi M, Keyamura Y, Nozako M, Koyama T, Kohashi M, Yasufuku R, Yoshikawa T, Fan J.

    9th Congress of the Asian-Pacific Society of Atherosclerosis and Vascular Diseases  2014.9 

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    Event date: 2014.9

    Language:English   Presentation type:Oral presentation(general)  

    Venue:Hong Kong, China  

  • Probucol inhibits the initiation of atherosclerosis in cholesterol-fed rabbits. International conference

    Niimi M

    The 2nd Sino-Japan Rabbit Model Meeting  2014.8 

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    Event date: 2014.8

    Language:English   Presentation type:Oral presentation(general)  

    Venue:Changchun, Jilin, China (Jilin University)  

  • Metabolome analysis of hyperlipidemic rabbits using a novel mass spectrometry

    Johno H, Mori Y, Yoshimura K, Niimi M, Kimura T, Nakamoto K, Fan J, Takeda S.

    The 3rd Scientific Meeting of Japan Rabbit Bioscience Association  2014.8 

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    Event date: 2014.8

    Language:Japanese   Presentation type:Oral presentation(general)  

  • Bisphenol A impairs insulin sensitivity, glucose metabolism and liver functions in WHHL rabbits.

    Fang C, Ning B, Waqar AB, Niimi M, Li S, Kang D, Dong S, Fan J.

    The 2nd Scientific Meeting of Japan Rabbit Bioscience Association  2013.8 

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    Event date: 2013.8

    Language:Japanese   Presentation type:Oral presentation(general)  

  • Probucol stabilizes the atherosclerotic plaques in WHHL rabbits.

    Li S, Liang J, Niimi M, Waqar AB, Kang D, Koike T, Shiomi M, Fan J.

    The 45th Annual Scientific Meeting of the Japan Atherosclerosis Society  2013.7 

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    Event date: 2013.7

    Language:English   Presentation type:Poster presentation  

  • Probucol stabilizes the atherosclerotic plaques in WHHL rabbits. International conference

    Li S, Niimi M, Waqar AB, Koike T, Shiomi M, Fan J.

    The 5th International Meeting on Rabbit Biotechnology  2013.6 

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    Event date: 2013.6

    Language:English   Presentation type:Poster presentation  

  • Add-on effect of probucol in atherosclerotic, cholesterol-fed rabbits treated with atorvastatin International conference

    Keyamura Y, Nagano C, Kohashi M, Niimi M, Nozako M, Koyama T, Okutsu R, Fukuda A, Mitani K, Itabe H, Yoshikawa T.

    81st Congress of the European Atherosclerosis Society  2013.6 

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    Event date: 2013.6

    Language:English   Presentation type:Poster presentation  

  • Human apolipoprotein A-II protects against atherosclerosis: a study using a novel transgenic rabbit

    Wang Y, Niimi M, Nishijima K, Waqar AB, Yu Y, Koike T, Kitajima S, Fan J.

    The 60th Annual Meeting of the Japanese Association for Laboratory Animal Science  2013.5 

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    Event date: 2013.5

    Language:Japanese   Presentation type:Oral presentation(general)  

  • Human Apolipoprotein Aii Protects Against Diet-induced Atherosclerosis in Transgenic Rabbits. International conference

    Wang Y, Niimi M, Waqar AB, Liu E, Zhang J, Chen YE, Fan J.

    American Heart Association Scientific Sessions 2012  2012.11 

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    Event date: 2012.11

    Language:English   Presentation type:Oral presentation(general)  

  • ApoAII-rich HDLs have anti-inflammatory functions International conference

    Koike T, Wang Y, Yu Y, Wang X, Niimi M, Waqar AB, Kitajima S, Nishijima K, Fan J.

    XVI International Symposium on Atherosclerosis  2012.3 

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    Event date: 2012.3

    Language:English   Presentation type:Poster presentation  

  • Probucol has different anti-atherogenic effects compared to atorvastatin.

    Niimi M, Nozako M, Koyama T, Nagano C, Kohashi M, Okutsu R, Kudo Y, Yoshikawa T, Koike T, Fan J.

    The 43rd Annual Scientific Meeting of the Japan Atherosclerosis Society  2011.7 

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    Event date: 2011.7

    Language:English   Presentation type:Poster presentation  

  • Effects of probucol and atorvastatin on atherosclerosis in rabbits

    Niimi M, Nozako M, Koyama T, Nagano C, Kohashi M, Okutsu R, Kudo Y, Yoshikawa T, Koike T, Fan J.

    The 15th Scientific Meeting of the Japanese Society of Vascular Pathology  2010.10 

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    Event date: 2010.10

    Language:Japanese   Presentation type:Oral presentation(general)  

  • Effects of probucol and atorvastatin on a cholesterol diet-induced rabbit atherosclerosis model

    Niimi M, Nozako M, Koyama T, Nagano C, Kohashi M, Okutsu R, Kudo Y, Yoshikawa T, Fan J.

    The 4th Scientific Forum on Rabbits for Medical sciences  2010.7 

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    Event date: 2010.7

    Language:Japanese   Presentation type:Oral presentation(general)  

  • Apolipoprotein B-48 in Lipoprotein Fraction Extracted from Human Aortic Plaque and Plasma from Sudden Cardiac Death Cases. International conference

    Nakano T, Niimi M, Nakajima K, Fujita M, Nakajima Y, Takeichi S, Tanaka A, Matsushima T, Kinoshita M, Teramoto T.

    76th Congress of the European Atherosclerosis Society  2007.6 

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    Event date: 2007.6

    Language:English   Presentation type:Poster presentation  

  • Detection of apoB-48 in lipoprotein fractions extracted from human aortic plaques.

    Nakano T, Niimi M, Nakajima K, Fujita MQ, Nakajima Y, Takeichi S, Tanaka A.

    The 37th Annual Scientific Meeting of the Japan Atherosclerosis Society  2005.7 

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    Event date: 2005.7

    Language:Japanese   Presentation type:Poster presentation  

  • Lipolytic characteristics of remnant-like particles by lipoprotein lipase/cholesterol esterase in vitro. International conference

    Nakano T, Niimi M, Inokuch T, Nakajima K.

    75th Congress of the European Atherosclerosis Society  2005.4 

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    Event date: 2005.4

    Language:English   Presentation type:Poster presentation  

  • Effect of CETP deficiency on exogenous lipoprotein metabolism.

    Inazu A, Nakajima K, Nakano T, Niimi M, Takada M, Katsuda S, Kawashiri M, Higashikata T, Kobayashi J, Mabuchi H.

    The 36th Annual Scientific Meeting of the Japan Atherosclerosis Society  2004.7 

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    Event date: 2004.7

    Language:Japanese   Presentation type:Poster presentation  

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Industrial Property Rights

  • Method of measuring cholesterol in remnant-like lipoproteins

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    Application no:2006-547888  Date applied:2005.11

    Patent/Registration no:4842538  Date registered:2011.10 

    Country of applicant:Foreign country  

  • High density lipoprotein-reactive peptides

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    Application no:2002-589513  Date applied:2002.5

    Patent/Registration no:3944083  Date registered:2007.4 

    Country of applicant:Foreign country  

Awards

  • 9th Congress of the Asia Pacific Society of Atherosclerosis and Vascular Diseases (APSAVD 2014) Educational Grant

    2014.8   Japan Atherosclerosis Society  

Teaching Experience (On-campus)

  • Integrated clinical medicine 1, Cardiovascular and respiratory system

    2024Year  Type of subject:Professional education (undergraduate)

  • Pathology-A

    2024Year  Type of subject:Professional education (undergraduate)

  • Life Science of the Human Body

    2023Year  Type of subject:Common education (undergraduate)

  • Integrated clinical medicine 1, Cardiovascular and respiratory system

    2023Year  Type of subject:Professional education (undergraduate)

  • Pathophysiology

    2023Year  Type of subject:Professional education (undergraduate)

  • Pathology-A

    2023Year  Type of subject:Professional education (undergraduate)

  • Human Pathology

    2023Year  Type of subject:Master's (Graduate School)

  • Tutorial Course 1, Cardiovascular-respiratory system

    2022Year  Type of subject:Professional education (undergraduate)

  • Life Science of the Human Body

    2022Year  Type of subject:Common education (undergraduate)

  • Pathophysiology 2

    2022Year  Type of subject:Professional education (undergraduate)

  • Human Pathology

    2022Year  Type of subject:Master's (Graduate School)

  • Life Science of the Human Body

    2021Year  Type of subject:Common education (undergraduate)

  • Tutorial Course 1, Cardiovascular-respiratory system

    2021Year  Type of subject:Professional education (undergraduate)

  • Pathophysiology 2

    2021Year  Type of subject:Professional education (undergraduate)

  • Pathology-A

    2021Year  Type of subject:Professional education (undergraduate)

  • Human Pathology

    2021Year  Type of subject:Master's (Graduate School)

  • Life Science of the Human Body

    2020Year  Type of subject:Common education (undergraduate)

  • Pathophysiology 2

    2020Year  Type of subject:Professional education (undergraduate)

  • Pathology-A

    2020Year  Type of subject:Professional education (undergraduate)

  • Human Pathology

    2020Year  Type of subject:Master's (Graduate School)

  • Human Pathology

    2019Year  Type of subject:Master's (Graduate School)

  • Tutorial Course 1, Cardiovascular-respiratory system

    2019Year  Type of subject:Professional education (undergraduate)

  • Pathophysiology 2

    2019Year  Type of subject:Professional education (undergraduate)

  • Molecular Pathology

    2019Year  Type of subject:Professional education (undergraduate)

  • Human Pathology

    2018Year  Type of subject:Master's (Graduate School)

  • Tutorial Course 1, Cardiovascular-respiratory system

    2018Year  Type of subject:Professional education (undergraduate)

  • Pathophysiology 2

    2018Year  Type of subject:Professional education (undergraduate)

  • Molecular Pathology

    2018Year  Type of subject:Professional education (undergraduate)

  • 人体病態学概論

    2017Year  Type of subject:Master's (Graduate School)

  • チュートリアル・コース1/2 呼吸器循環器

    2017Year  Type of subject:Professional education (undergraduate)

  • 病態・生理論2

    2017Year  Type of subject:Professional education (undergraduate)

  • Molecular Pathology

    2017Year  Type of subject:Professional education (undergraduate)

  • 人体病態学概論

    2016Year  Type of subject:Master's (Graduate School)

  • チュートリアル・コース1/2 呼吸器循環器

    2016Year  Type of subject:Professional education (undergraduate)

  • 病態・生理論2

    2016Year  Type of subject:Professional education (undergraduate)

  • Molecular Pathology

    2016Year  Type of subject:Professional education (undergraduate)

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Professional Memberships

  • Japan Atherosclerosis Society (JAS)

  • European Atherosclerosis Society

  • American Heart Association

  • Japanese Association for Laboratory Animal Science

  • The Japanese Society of Pathology

  • The Japanese Biochemical Society

  • Japan Rabbit Bioscience Association

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Committee Memberships

  • Japan Atherosclerosis Society   Councilor  

    2016.7   

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    Committee type:Society

  • Japan Rabbit Bioscience Association   Board of Director  

    2018.7   

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    Committee type:Society

  • Metabolism and Translational Medicine   Editorial Board Member  

    2023.1