Japan Immunoresearch Laboratories Co., Ltd.   Diagnostic Division   Chief

2003.6 - 2007.10

Japan Immunoresearch Laboratories Co., Ltd.   Diagnostic Division

1996.4 - 2003.6

Role of lipoprotein lipase on exercise effects

Grant number：16K08607  2016.10 - 2019.3

Japan Society for the Promotion of Science (JSPS)  Grants-in-Aid for Scientific Research (KAKENHI)  Grant-in-Aid for Scientific Research (C)

Kazutoshi Nishijima, Yuichiro Nishida, Manabu Niimi

Elucidation of roles of MMP-1 in atherosclerosis and plaque rupture using transgenic rabbits

Grant number：26460486  2014.4 - 2017.3

Japan Society for the Promotion of Science (JSPS)  Grants-in-Aid for Scientific Research (KAKENHI)  Grant-in-Aid for Scientific Research (C)

Manabu Niimi, Kazutoshi Nishijima, Jianglin Fan

The Combined Administration of Vitamin C and Copper Induces a Systemic Oxidative Stress and Kidney Injury. Reviewed

Jiang R, Sui Y, Hong J, Niimi M, Yan Q, Shi Z, Yao J.

Biomolecules.   13 ( 1 )   143   2023.1( ISSN：2218-273X )

Examining atherosclerotic lesions in three dimensions at the nanometer scale with cryo-FIB-SEM. Reviewed

Capua-Shenkar J, Varsano N, Itzhak NR, Kaplan-Ashiri I, Rechav K, Jin X, Niimi M, Fan J, Kruth HS, Addadi L.

Proc Natl Acad Sci U S A.   119 ( 34 )   e2205475119   2022.8( ISSN：0027-8424 )

Is apoCIII-Lowering A Double-Edged Sword? Reviewed

Tang X, Zhou H, Yan H, Niimi M, Fan J.

J Atheroscler Thromb.   29 ( 7 )   1117 - 1124   2022.7( ISSN：1340-3478 )

Pathological Investigations of Intracranial Atherosclerosis Using Multiple Hypercholesterolemic Rabbit Models. Reviewed

Tang X, Niimi M, Zhou H, Chen L, Chen Y, Yan H, Shiomi M, Fan J.

Front Endocrinol.   13   834207   2022.4( ISSN：1664-2392 )

Tanshinone IIA Stimulates Cystathionine γ-Lyase Expression and Protects Endothelial Cells from Oxidative Injury. Reviewed

Yan Q, Mao Z, Hong J, Gao K, Niimi M, Mitsui T, Yao J.

Antioxidants.   10 ( 7 )   1007   2021.6( ISSN：2076-3921 )

Strategies for Highly Efficient Rabbit Sperm Cryopreservation. Reviewed

Nishijima K, Kitajima S, Matsuhisa F, Niimi M, Wang CC, Fan J.

Animals.   11 ( 5 )   1220   2021.4( ISSN：2076-2615 )

Endothelial lipase exerts its anti-atherogenic effect through increased catabolism of β-VLDLs. Reviewed

Yan H, Niimi M, Wang C, Chen Y, Zhou H, Matsuhida F, Nishijima K, Kitajima S, Nakajima K, Murakami M, Zhang J, Chen YE, Fan J.

J Atheroscler Thromb.   28 ( 2 )   157 - 168   2021.2( ISSN：1340-3478 )

Isolation and analysis of plasma lipoproteins by ultracentrifugation. Reviewed

Niimi M, Yan H, Chen YJ, Wang Y, Fan J.

J Vis Exp.   167   e61790   2021.1( ISSN：1940-087X )

Hyperlipidemic rabbit models for anti-atherosclerotic drug development. Reviewed

Niimi M, Chen YJ, Yan H, Wang Y, Koike T, Fan J.

Appl Sci.   10 ( 23 )   8681   2020.12( ISSN：2076-3417 )

Apolipoprotein CIII deficiency protects against atherosclerosis in knock-out rabbits. Reviewed

Yan H*, Niimi M*, Matsuhisa F, Zhou H, Kitajima S, Chen YJ, Wang C, Yang X, Yao J, Yang D, Zhang J, Murakami M, Nakajima K, Wang Y, Liu E, Liang J, Chen YE, Fan J.

Arterioscler Thromb Vasc Biol.   40 ( 9 )   2095 - 2107   2020.9( ISSN：1079-5642 )

Sex hormones affect endothelial lipase-mediated lipid metabolism and atherosclerosis. Reviewed

Wang C, Niimi M, Kitajima S, Matsuhisa F, Yan H, Dong S, Liang J, Fan J.

Lipids Health Dis.   18 ( 1 )   226   2019.12( ISSN：1476-511X )

Macrophage-derived matrix metalloproteinase-1 enhances aortic aneurysm formation in transgenic rabbits. Reviewed

Niimi M, Nishijima K, Kitajima S, Matsuhisa F, Satoh K, Yamazaki H, Zhang J, Chen YE, Fan J.

J Biomed Res.   33 ( 4 )   271 - 279   2019.7( ISSN：1674-8301 )

Treatment of atherosclerosis by traditional Chinese medicine: Questions and quandaries. Reviewed

Wang C, Niimi M, Watanabe T, Wang Y, Liang J, Fan J.

ATHEROSCLEROSIS   277   136 - 144   2018.8( ISSN：0021-9150 )

Detection of potential new biomarkers of atherosclerosis by probe electrospray ionization mass spectrometry. Reviewed

Johno H, Yoshimira K, Mori Y, Kimura T, Niimi M, Yamada M, Tanigawa T, Fan J, Takeda S

Metabolomics   14 ( 4 )   38   2018.4( ISSN：1573-3882 )

Principles and Applications of Rabbit Models for Atherosclerosis Research. Reviewed

Fan J, Chen Y, Yan H, Niimi M, Wang Y, Liang J.

Journal of Atherosclerosis and Thrombosis   25 ( 3 )   213 - 220   2018.3( ISSN：1340-3478 )

Glutathione inhibits antibody and complement-mediated immunologic cell injury via multiple mechanisms. Reviewed

Zhang Z, Zhang X, Fang X, Niimi M, Huang Y, Piao H, Gao S, Fan J, Yao J.

Redox Biology   12   571 - 581   2017.8( ISSN：2213-2317 )

Comparative studies of three cholesteryl ester transfer proteins and their interactions with known inhibitors. Reviewed

Wang Z, Niimi M, Ding Q, Liu Z, Wang L, Zhang J, Xu J, Fan J.

PLoS One   12 ( 8 )   e0180772   2017.8( ISSN：1932-6203 )

Increased hepatic expression of endothelial lipase inhibits cholesterol diet-induced hypercholesterolemia and atherosclerosis in transgenic rabbits. Reviewed

Wang C, Nishijima K, Kitajima S, Niimi M, Yan H, Chen Y, Ning B, Matsuhisa F, Liu E, Zhang J, Chen YE, Fan J.

Arterioscler Thromb Vasc Biol.   37 ( 7 )   1282 - 1289   2017.7( ISSN：1079-5642 )

Deficiency of cholesteryl ester transfer protein protects against atherosclerosis in rabbits. Reviewed

Zhang J*, Niimi M*, Yang D, Liang J, Xu J, Kimura T, Mattew AV, Guo Y, Fan Y, Zhu T, Song J, Ackermann R, Koike Y, Schwendeman A, Lai L, Pennathur S, Garcia-Barrio M, Fan J, Chen YE.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY   37 ( 6 )   1068 - 1075   2017.6( ISSN：1079-5642 )

Suramin inhibits antibody binding to cell surface antigens and disrupts complement-mediated mesangial cell lysis. Reviewed

JOURNAL OF PHARMACOLOGICAL SCIENCES   132 ( 4 )   224 - 234   2016.12( ISSN：1347-8613 )

Hyperlipidemia-associated gene variations and expression patterns revealed by whole-genome and transcriptome sequencing of rabbit models. Reviewed

Wang Z, Zhang J, Li H, Li J, Niimi M, Ding G, Chen H, Xu J, Zhang H, Xu Z, Dai Y, Gui T, Li S, Liu Z, Wu S, Cao M, Zhou L, Lu X, Wang J, Yang J, Fu Y, Yang D, Song J, Zhu T, Li S, Ning B, Wang Z, Koike T, Shiomi M, Liu E, Chen L, Fan J, Chen YE, Li Y.

Scientific Reports   6   26942   2016.6( ISSN：2045-2322 )

Angiotensin II destabilizes coronary plaques in Watanabe heritable hyperlipidemic rabbits. Reviewed

Li S, Wang YN, Niimi M, Ning B, Chen Y, Kang D, Waqar AB, Wang Z, Yu Q, Liu E, Zhang J, Shiomi M, Chen YE, Fan J.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY   36 ( 5 )   810 - 816   2016.5( ISSN：1079-5642 )

ApoE knockout rabbits: A novel model for the study of human hyperlipidemia. Reviewed

Niimi M, Yang D, Kitajima S, Ning B, Wang C, Li S, Liu E, Zhang J, Chen YE, Fan J.

ATHEROSCLEROSIS   245   187 - 193   2016.2( ISSN：0021-9150 )

Bisphenol A exposure induces metabolic disorders and enhances atherosclerosis in hyperlipidemic rabbits. Reviewed

Fang C, Ning B, Waqar AB, Niimi M, Li S, Satoh K, Shiomi M, Ye T, Dong S, Fan J.

JOURNAL OF APPLIED TOXICOLOGY   35 ( 9 )   1058 - 1070   2015.9( ISSN：0260-437X )

Dietary cholesterol atherogenic changes in juvenile rabbits. Reviewed

Keyamura Y, Nagano C, Kohashi M, Niimi M, Nozako M, Koyama T, Itabe H, Yoshikawa T.

BIOLOGICAL & PHARMACEUTICAL BULLETIN   38 ( 5 )   785 - 788   2015.5( ISSN：0918-6158 )

Bisphenol A exposure enhances atherosclerosis in WHHL rabbits. Reviewed

Fang C, Ning B, Waqar AB, Niimi M, Li S, Satoh K, Shiomi M, Ye T, Dong S, Fan J.

PLoS One.   9 ( 10 )   e110977   2014.10( ISSN：1932-6203 )

Probucol suppresses macrophage infiltration and MMP expression in atherosclerotic plaques of WHHL rabbits. Reviewed

Li S, Liang J, Niimi M, Waqar AB, Kang D, Koike T, Wang Y, Shiomi M, Fan J.

J Atheroscler Thromb.   21 ( 7 )   648 - 658   2014.7( ISSN：1340-3478 )

Add-on effect of probucol in atherosclerotic, cholesterol-fed rabbits treated with atorvastatin. Reviewed

Keyamura Y, Nagano C, Kohashi M, Niimi M, Nozako M, Koyama T, Yasufuku R, Imaizumi A, Itabe H, Yoshikawa T.

PLoS One.   9 ( 5 )   e96929   2014.5( ISSN：1932-6203 )

Probucol inhibits the initiation of atherosclerosis in cholesterol-fed rabbits. Reviewed

Niimi M, Keyamura Y, Nozako M, Koyama T, Kohashi M, Yasufuku R, Yoshikawa T, Fan J.

Lipids Health Dis.   12   166   2013.11( ISSN：1476-511X )

Human Apolipoprotein A-II Protects Against Diet-Induced Atherosclerosis in Transgenic Rabbits. Reviewed

Wang Y*, Niimi M*, Nishijima K, Waqar AB, Yu Y, Koike T, Kitajima S, Liu E, Inoue T, Kohashi M, Keyamura Y, Yoshikawa T, Zhang J, Ma L, Zha X, Watanabe T, Asada Y, Chen YE, Fan J.

Arterioscler Thromb Vasc Biol.   33 ( 2 )   224 - 231   2013.2( ISSN：1079-5642 )

Cilostazol inhibits accumulation of triglyceride in aorta and platelet aggregation in cholesterol-fed rabbits. Reviewed

Ito H, Uehara K, Matsumoto Y, Hashimoto A, Nagano C, Niimi M, Miyakoda G, Nagano K.

PLoS One.   7   e3937   2012.6( ISSN：1932-6203 )

Cholesterol efflux from J774 macrophages and Fu5AH hepatoma cells to serum is preserved in CETP-deficient patients. Reviewed

Miwa K, Inazu A, Kawashiri M, Nohara A, Higashikata T, Kobayashi J, Koizumi J, Nakajima K, Nakano T, Niimi M, Mabuchi H, Yamagishi M.

Clin Chim Acta.   402   19 - 24   2009.4( ISSN：0009-8981 )

Detection of apolipoproteins B-48 and B-100 carrying particles in lipoprotein fractions extracted from human aortic atherosclerotic plaques in sudden cardiac death cases. Reviewed

Nakano T, Nakajima K, Niimi M, Fujita MQ, Nakajima Y, Takeichi S, Kinoshita M, Matsushima T, Teramoto T, Tanaka A.

CLINICA CHIMICA ACTA   390   38 - 43   2008.4( ISSN：0009-8981 )

Decreased post-prandial triglyceride response and diminished remnant lipoprotein formation in cholesteryl ester transfer protein (CETP) deficiency. Reviewed

Inazu A, Nakajima K, Nakano T, Niimi M, Kawashiri MA, Nohara A, Kobayashi J, Mabuchi H.

Atherosclerosis.   196   953 - 957   2008.2( ISSN：0021-9150 )

Evidence for conformational change of fatty acid-binding protein accompanying binding of hydrophobic ligands. Reviewed

Honma Y, Niimi M, Uchiumi T, Takahashi Y, Odani S.

J Biochem.   116   1025 - 1029   1994.10( ISSN：0021-924X )

A novel model for studying hypertriglyceridemia: Apo A-V knockout rabbits

Niimi M, Matsuhisa F, Kitajima S, Fan J.

The 55th Annual Scientific Meeting of the Japanese Atherosclerosis Society  2023.7 

A novel model for studying human triglycerides metabolism: Apo A-V knockout rabbits

Niimi M, Matsuhisa F, Kitajima S, Fan J.

The 70th Annual Meeting of the Japanese Association for Laboratory Animal Science  2023.5 

Angiotensin II aggravates atherosclerotic lesions and enhances plaque erosion in rabbits. International conference

Chen Y, Zhu M, Wang Y, Niimi M, Fan J.

The 4th Japan & China Joint Rabbit Biotechnology Meeting  2023.2 

ApoE-null chylomicron remnants exacerbate atherosclerosis in rabbits.

Niimi M, Matsuhisa F, Tang X, Chen L, Chen Y, Yan H, Kitajima S, Fan J.

The 6th Scientific Meeting of Japan Rabbit Bioscience Association  2023.2 

Apolipoprotein CIII deficiency exacerbates diet-induced fatty liver and insulin resistance in knock-out rabbits.

Tang X, Zhou H, Yan H, Niimi M, Fan J.

The 6th Scientific Meeting of Japan Rabbit Bioscience Association  2023.2 

Apolipoprotein CIII Deficiency Protects Against Atherosclerosis in Knockout Rabbits. International conference

Yan H, Niimi M, Matsuhisa F, Yang X, Zhou H, Kitajima S, Chen Y, Wang C, Zhang J, Liu E, Liang J, Chen YE, Lai L, Fan J.

The 4th Japan & China Joint Rabbit Biotechnology Meeting  2023.2 

ApoB48-containing chylomicron remnants exacerbate atherosclerosis

Niimi M, Tang X, Narita K, Fan J.

The 54th Annual Scientific Meeting of the Japanese Atherosclerosis Society  2022.7 

Apolipoprotein CIII deficient knock-out rabbits are susceptible to diet-induced fatty liver and insulin resistance.

Tang X, Zhou H, Yan H, Niimi M, Fan J.

The 54th Annual Scientific Meeting of the Japanese Atherosclerosis Society  2022.7 

Pathological investigations of intracranial atherosclerosis using multiple rabbit models. International conference

Tang X, Niimi M, Fan J.

The 19th International Symposium on Atherosclerosis  2021.10 

Apolipoprotein CIII deficiency inhibits cholesterol diet-induced hyperlipidemia and atherosclerosis in knockout rabbits. International conference

Yan H, Niimi M, Matsuhisa F, Yang X, Zhou H, Kitajima S,Chen Y, Wang C, Yao J, Yang D, Zhang J, Murakami M, Nakajima K, Wang Y, Liu E, Liang J, Lai L, Chen YE, Fan J.

The 19th International Symposium on Atherosclerosis  2021.10 

Apolipoprotein CIII Deficiency Protects Against Atherosclerosis in Knockout Rabbits.

Yan H, Niimi M, Matsuhisa F, Zhou F, Kitajima S, Chen Y, Wang C, Yang X, Yang D, Zhang J, Wang Y, Liu E, Liang J, Chen YE, Fan J.

The 53rd Annual Scientific Meeting of the Japanese Atherosclerosis Society  2021.10 

Pathological analysis of intracranial atherosclerosis in hyperlipidemic rabbits

Tang X, Niimi M, Fan J.

The 53rd Annual Scientific Meeting of the Japanese Atherosclerosis Society  2021.10 

Plasma chylomicron-remnants accelerate atherosclerosis: Study of ApoE-deficient rabbits

Niimi M, Matsuhisa F, Zhou F, Chen Y, Yan H, Kitajima S, Fan J.

The 53rd Annual Scientific Meeting of the Japanese Atherosclerosis Society  2021.10 

Matrix metalloproteinase and atherosclerotic diseases: Findings from the rabbits model

Niimi M, Chen Y, Fan J.

The 53rd Annual Scientific Meeting of the Japanese Atherosclerosis Society  2021.10 

Plasma chylomicron-remnants accelerate atherosclerosis in ApoE-deficient rabbits

Niimi M, Matsuhisa F, Kitajima S, Fan J.

The 110th Annual Meeting of the Japanese Society of Pathology  2021.4 

Deletion of the apoCIII gene in knockout rabbits attenuates cholesterol diet-induced hyperlipidemia and protects against atherosclerosis. International conference

Yan H, Niimi M, Zhou H, Matsuhisa F, Kitajima S, Yang C, Chen Y, Murakami M, Nakajima K, Liang J, Zhang J, Chen YE, Yao J, Fan J.

88th EAS (European Atherosclerosis Society) Congress 2020  2020.10 

Endothelial lipase exerts its anti-atherogenic effect through increased catabolism of beta-VLDLs International conference

Wang C, Niimi M, Yan H, Zhou H, Fan J.

88th EAS (European Atherosclerosis Society) Congress 2020  2020.10 

Apolipoprotein AII: A new role in lipoprotein metabolism and atherosclerosis.

Fan J, Niimi M, Koike T.

The 52nd Annual Scientific Meeting of the Japan Atherosclerosis Society  2020.7 

Cholesterol efflux capacity of an amphipathic helical peptide in apolipoprotein B-100

Niimi M, Saitou F, Kanatani K, Nakajima K.

The 52nd Annual Scientific Meeting of the Japan Atherosclerosis Society  2020.7 

Characterization of plasma lipids and lipoprotein metabolism of apoCIII knockout rabbits.

Yan H, Niimi M, Zhou H, Matsuhisa F, Kitajima S, Chen Y, Zhang J, Chen YE, Fan J.

The 52nd Annual Scientific Meeting of the Japan Atherosclerosis Society  2020.7 

Endothelial lipase attenuates cholesterol diet-induced hypercholesterolemia and protects against atherosclerosis in transgenic rabbits. International conference

Niimi M, Wang C, Yan H, Chen Y, Zhou H, Matsuhisa F, Nishijima K, Kitajima S, Zhang J, Chen YE, Fan J.

42nd Annual Scientific Meeting of the European Lipoprotein Club (ELC)  2019.9 

Deletion of the apoCIII gene in knockout rabbits enhances the catabolism of triglyceride-rich lipoproteins and attenuates cholesterol diet-induced hyperlipidemia. International conference

Yan H, Niimi M, Kitajima S, Zhou H, Matsuhisa F, Chen Y, Zhang J, Chen YE, Fan J.

8th International Congress on Lipid & Atherosclerosis (ICoLA 2019)  2019.9 

Endothelial lipase exerts its anti-atherogenic effect through plasma lipid-lowring effect.

Niimi M, Yan H, Chen Y, Zhou H, Wang C, Matsuhisa F, Nishijima K, Kitajima S, Fan J.

The 51st Annual Scientific Meeting of the Japan Atherosclerosis Society  2019.7 

CETP inhibition and atherosclerosis therapy: myth or fact. Invited International conference

Niimi M, Fan J.

China-Japan International Conference on Atherosclerosis 2018  2018.8 

Characterization of apolipoprotein C-III knockout rabbits.

Yan H, Niimi M, Matsuhisa F, Kitajima S, Chen YE, Fan J.

The 5th Scientific Meeting of Japan Rabbit Bioscience Association  2018.7 

Comparison of cryoprotectants for ultra-rapid vitrification (Cryotop method) in rabbit embryos. International conference

Matsuhisa F, Akiyoshi T, Matsuo K, Morimoto M, Niimi M, Fan J, Kitajima S.

7th International Congress on Rabbit Biotechnology 2017  2017.8 

Increased hepatic expression of endothelial lipase inhibits cholesterol diet-induced hypercholesterolemia and atherosclerosis in transgenic rabbits. International conference

Wang C, Nishijima K, Kitajima S, Niimi M, Yan H, Chen Y, Ning B, Matsuhisa F, Liu E, Zhang J, Chen YE, Fan J.

7th International Congress on Rabbit Biotechnology 2017  2017.8 

Macrophage-derived matrix metalloproteinase-1 accelerates aortic aneurysm formation in transgenic rabbits.

Niimi N, Nishijima K, Kitajima S, Matsuhisa F Satoh K, Yamazaki H, Fan J.

The 49th Annual Scientific Meeting of the Japan Atherosclerosis Society  2017.7 

Deficiency of CETP protects against atherosclerosis in rabbits

Kimura T, Niimi M, Zhang J, Chen YE, Fan J.

The 4th Rabbit Bioscience Association Meeting  2016.8 

Angiotensin II destabilizes coronary plaques in WHHL rabbits.

Li S, Wang YN, Niimi M, Ning B, Chen Y, Kang D, Wang Z, Yu Q, Waqar AB, Liu E, Zhang J, Shiomi M, Chen YE, Fan J.

The 48th Annual Scientific Meeting of the Japan Atherosclerosis Society  2016.7 

Hepatic overexpression of endothelial lipase reduces plasma HDL levels in transgenic rabbits.

Wang C, Nishijima K, Kitajima S, Niimi N, Ning B, Fan J.

The 48th Annual Scientific Meeting of the Japan Atherosclerosis Society  2016.7 

A novel model for the study of human atherosclerosis: Apo E knockout rabbits

Niimi M, Kitajima S, Matsuhisa F, Ning B, Wang C, Yang D, Zhang J, Chen YE, Fan J.

The 63rd Annual Meeting of Japanese Association for Laboratory Animal Science  2016.5 

Comparison of cryopreservation devices and solutions in thevitrification of rabbit embryos

Matsuhisa F, Akiyoshi T, Niimi M, Morimoto M, Fan J, Kitajima S.

The 63rd Annual Meeting of Japanese Association for Animal Science  2016.5 

ApoE knockout rabbits: a novel model for the study of human hyperlipidemia.

Niimi N, Ning B, Wang C, Li S, Zhang J, Chen YE, Fan J.

The 47th Annual Scientific Meeting of the Japan Atherosclerosis Society  2015.7 

CETP Deficiency in Rabbits Protects High Fat High Cholesterol Diet Induced Atherosclerosis. International conference

Zhang J, Xu J, Liang J, Yang D, Guo Y, Zhu T, Song J, Niimi M, Lai L, Fan J, Chen YE.

Arteriosclerosis, Thrombosis and Vascular Biology/ Peripheral Vascular Disease Scientific Sessions 2015  2015.5 

Probucol inhibits the initiation of atherosclerosis in cholesterol-fed rabbits International conference

Niimi M, Keyamura Y, Nozako M, Koyama T, Kohashi M, Yasufuku R, Yoshikawa T, Fan J.

9th Congress of the Asian-Pacific Society of Atherosclerosis and Vascular Diseases  2014.9 

Probucol inhibits the initiation of atherosclerosis in cholesterol-fed rabbits. International conference

Niimi M

The 2nd Sino-Japan Rabbit Model Meeting  2014.8 

Metabolome analysis of hyperlipidemic rabbits using a novel mass spectrometry

Johno H, Mori Y, Yoshimura K, Niimi M, Kimura T, Nakamoto K, Fan J, Takeda S.

The 3rd Scientific Meeting of Japan Rabbit Bioscience Association  2014.8 

Bisphenol A impairs insulin sensitivity, glucose metabolism and liver functions in WHHL rabbits.

Fang C, Ning B, Waqar AB, Niimi M, Li S, Kang D, Dong S, Fan J.

The 2nd Scientific Meeting of Japan Rabbit Bioscience Association  2013.8 

Probucol stabilizes the atherosclerotic plaques in WHHL rabbits.

Li S, Liang J, Niimi M, Waqar AB, Kang D, Koike T, Shiomi M, Fan J.

The 45th Annual Scientific Meeting of the Japan Atherosclerosis Society  2013.7 

Probucol stabilizes the atherosclerotic plaques in WHHL rabbits. International conference

Li S, Niimi M, Waqar AB, Koike T, Shiomi M, Fan J.

The 5th International Meeting on Rabbit Biotechnology  2013.6 

Add-on effect of probucol in atherosclerotic, cholesterol-fed rabbits treated with atorvastatin International conference

Keyamura Y, Nagano C, Kohashi M, Niimi M, Nozako M, Koyama T, Okutsu R, Fukuda A, Mitani K, Itabe H, Yoshikawa T.

81st Congress of the European Atherosclerosis Society  2013.6 

Human apolipoprotein A-II protects against atherosclerosis: a study using a novel transgenic rabbit

Wang Y, Niimi M, Nishijima K, Waqar AB, Yu Y, Koike T, Kitajima S, Fan J.

The 60th Annual Meeting of the Japanese Association for Laboratory Animal Science  2013.5 

Human Apolipoprotein Aii Protects Against Diet-induced Atherosclerosis in Transgenic Rabbits. International conference

Wang Y, Niimi M, Waqar AB, Liu E, Zhang J, Chen YE, Fan J.

American Heart Association Scientific Sessions 2012  2012.11 

ApoAII-rich HDLs have anti-inflammatory functions International conference

Koike T, Wang Y, Yu Y, Wang X, Niimi M, Waqar AB, Kitajima S, Nishijima K, Fan J.

XVI International Symposium on Atherosclerosis  2012.3 

Probucol has different anti-atherogenic effects compared to atorvastatin.

Niimi M, Nozako M, Koyama T, Nagano C, Kohashi M, Okutsu R, Kudo Y, Yoshikawa T, Koike T, Fan J.

The 43rd Annual Scientific Meeting of the Japan Atherosclerosis Society  2011.7 

Effects of probucol and atorvastatin on atherosclerosis in rabbits

Niimi M, Nozako M, Koyama T, Nagano C, Kohashi M, Okutsu R, Kudo Y, Yoshikawa T, Koike T, Fan J.

The 15th Scientific Meeting of the Japanese Society of Vascular Pathology  2010.10 

Effects of probucol and atorvastatin on a cholesterol diet-induced rabbit atherosclerosis model

Niimi M, Nozako M, Koyama T, Nagano C, Kohashi M, Okutsu R, Kudo Y, Yoshikawa T, Fan J.

The 4th Scientific Forum on Rabbits for Medical sciences  2010.7 

Apolipoprotein B-48 in Lipoprotein Fraction Extracted from Human Aortic Plaque and Plasma from Sudden Cardiac Death Cases. International conference

Nakano T, Niimi M, Nakajima K, Fujita M, Nakajima Y, Takeichi S, Tanaka A, Matsushima T, Kinoshita M, Teramoto T.

76th Congress of the European Atherosclerosis Society  2007.6 

Detection of apoB-48 in lipoprotein fractions extracted from human aortic plaques.

Nakano T, Niimi M, Nakajima K, Fujita MQ, Nakajima Y, Takeichi S, Tanaka A.

The 37th Annual Scientific Meeting of the Japan Atherosclerosis Society  2005.7 

Lipolytic characteristics of remnant-like particles by lipoprotein lipase/cholesterol esterase in vitro. International conference

Nakano T, Niimi M, Inokuch T, Nakajima K.

75th Congress of the European Atherosclerosis Society  2005.4 

Effect of CETP deficiency on exogenous lipoprotein metabolism.

Inazu A, Nakajima K, Nakano T, Niimi M, Takada M, Katsuda S, Kawashiri M, Higashikata T, Kobayashi J, Mabuchi H.

The 36th Annual Scientific Meeting of the Japan Atherosclerosis Society  2004.7 

Pathophysiology

2023Year  Type of subject：Professional education (undergraduate)

Pathology-A

2023Year  Type of subject：Professional education (undergraduate)

Tutorial Course 1, Cardiovascular-respiratory system

2022Year  Type of subject：Professional education (undergraduate)

Life Science of the Human Body

2022Year  Type of subject：Common education (undergraduate)

Pathophysiology 2

2022Year  Type of subject：Professional education (undergraduate)

Human Pathology

2022Year  Type of subject：Master's (Graduate School)

Life Science of the Human Body

2021Year  Type of subject：Common education (undergraduate)

Tutorial Course 1, Cardiovascular-respiratory system

2021Year  Type of subject：Professional education (undergraduate)

Pathophysiology 2

2021Year  Type of subject：Professional education (undergraduate)

Pathology-A

2021Year  Type of subject：Professional education (undergraduate)

Human Pathology

2021Year  Type of subject：Master's (Graduate School)

Life Science of the Human Body

2020Year  Type of subject：Common education (undergraduate)

Pathophysiology 2

2020Year  Type of subject：Professional education (undergraduate)

Pathology-A

2020Year  Type of subject：Professional education (undergraduate)

Human Pathology

2020Year  Type of subject：Master's (Graduate School)

Human Pathology

2019Year  Type of subject：Master's (Graduate School)

Tutorial Course 1, Cardiovascular-respiratory system

2019Year  Type of subject：Professional education (undergraduate)

Pathophysiology 2

2019Year  Type of subject：Professional education (undergraduate)

Molecular Pathology

2019Year  Type of subject：Professional education (undergraduate)

Human Pathology

2018Year  Type of subject：Master's (Graduate School)

Tutorial Course 1, Cardiovascular-respiratory system

2018Year  Type of subject：Professional education (undergraduate)

Pathophysiology 2

2018Year  Type of subject：Professional education (undergraduate)

Molecular Pathology

2018Year  Type of subject：Professional education (undergraduate)

人体病態学概論

2017Year  Type of subject：Master's (Graduate School)

チュートリアル・コース1/２　呼吸器循環器

2017Year  Type of subject：Professional education (undergraduate)

病態・生理論２

2017Year  Type of subject：Professional education (undergraduate)

Molecular Pathology

2017Year  Type of subject：Professional education (undergraduate)

人体病態学概論

2016Year  Type of subject：Master's (Graduate School)

チュートリアル・コース1/２　呼吸器循環器

2016Year  Type of subject：Professional education (undergraduate)

病態・生理論2

2016Year  Type of subject：Professional education (undergraduate)

Molecular Pathology

2016Year  Type of subject：Professional education (undergraduate)

The Japanese Biochemical Society

Japan Rabbit Bioscience Association