Updated on 2024/03/25

写真a

 
Takahashi Hironori
 
Organization
Graduate Faculty of Interdisciplinary Research Faculty of Medicine Basic Science for Clinical Medicine (Anatomy and Structural Biology) Assistant Professor
Title
Assistant Professor

Research History

  • 山梨大学医学部解剖学講座構造生物学教室助教

    2016.6

  • 日本学術振興会特別研究員DC2

    2015.4 - 2016.6

Education

  • The University of Tokyo   Graduate School of Medicine

    - 2018.12

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    Country: Japan

    Notes: Ph.D.

    Course: Doctor course

  • The University of Tokyo   Graduate School of Medicine   Department of Radiology and Biomedical Engineering

    2012.4 - 2016.6

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    Country: Japan

    Course: Doctor course

  • The University of Tokyo   Graduate School of Medicine   Department of Medical Science

    2010.4 - 2012.3

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    Country: Japan

    Course: Master course

  • The University of Tokyo   Faculty of Science   Department of Biological Sciences

    2008.4 - 2010.3

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    Country: Japan

  • The University of Tokyo   College of Arts and Sciences   Natural Sciences I

    2006.4 - 2008.3

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    Country: Japan

Degree

  • Ph.D. ( 2018.12   The University of Tokyo )

Research Areas

  • Life Science / Cell biology

  • Life Science / Neuroscience-general

  • Nanotechnology/Materials / Bio chemistry

Research Projects

  • 自動追跡ロボット技術と超高速三次元イメージング技術の統合による脳動作原理の解明

    2022.10 - 2025.3

    国際共同研究加速基金(国際共同研究強化(B))

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    Authorship:Coinvestigator(s)  Grant type:Competitive  Type of fund::Science research expense

  • 自閉スペクトラム症における感覚情報処理の解明

    2022.4 - 2023.3

    山梨県  山梨県 令和4年度若手研究者奨励事業 

    高橋光規

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    Authorship:Principal investigator  Type of fund::Donation

  • 自閉スペクトラム症における神経変動性機構の解明

    2022.1 - 2024.4

    公益財団法人 上原記念生命科学財団  研究奨励金

    高橋光規

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    Authorship:Principal investigator  Type of fund::Donation

  • 光により神経活動の全てを制御する完全光学神経生理学法TAONの開発

    2021.7

    公益財団法人 武田科学振興財団  医学系研究助成(精神・神経・脳領域)

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    Authorship:Principal investigator  Type of fund::Donation

  • 光機能性有機小分子による神経活動制御を活用した神経回路機能の解析

    2021.4 - 2024.3

    若手研究

    高橋光規

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    Authorship:Principal investigator  Type of fund::Science research expense

  • 新規ケージド化合物を用いた線虫のオールオプティカル神経行動解析法の開発

    2019.4 - 2021.3

    若手研究

    高橋光規

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    Authorship:Principal investigator  Type of fund::Science research expense

  • 神経シナプスにおける微細構造構築メカニズムの解明

    2017.6 - 2018.6

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Papers

  • Neural and behavioral control in Caenorhabditis elegans by a yellow-light–activatable caged compound Reviewed Major achievement

    Hironori Takahashi, Mako Kamiya, Minoru Kawatani, Keitaro Umezawa, Yoshiaki Ukita, Shinsuke Niwa, Toshiyuki Oda, and Yasuteru Urano

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA   2021.2( ISSN:0027-8424 )

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1073/pnas.2009634118

  • Disease-associated mutations hyperactivate KIF1A motility and anterograde axonal transport of synaptic vesicle precursors Reviewed Major achievement

    Kyoko Chiba, Hironori Takahashi, Min Chen, Hiroyuki Obinata, Shogo Arai, Koichi Hashimoto, Toshiyuki Oda, Richard J. McKenney, and Shinsuke Niwa

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA   2019.8( ISSN:0027-8424 )

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1073/pnas.1905690116

  • KIF1Bβ mutations detected in hereditary neuropathy impair IGF1R transport and axon growth. Reviewed Major achievement

    Xu F, Takahashi H, Tanaka Y, Ichinose S, Niwa S, Wicklund MP, Hirokawa N

    JOURNAL OF CELL BIOLOGY   2018.8( ISSN:0021-9525 )

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Factors affecting the uncaging efficiency of 500 nm light-activatable BODIPY caging group Reviewed

    Minoru Kawatani, Mako Kamiya, Hironori Takahashi, Yasuteru Urano

    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS   2018.1( ISSN:0960-894X )

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Spatiotemporal activation of melecules within cells using silica nanoparticles responsive to blue-green light Reviewed Major achievement

    Journal of Materials Chemistry B   3   7427 - 7433   2015.8( ISSN:2050-750X )

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    Language:English  

  • 可視光で細胞機能を制御する小分子プローブ群の開発 Major achievement

    神谷真子,高橋光規,浦野泰照

    生体の科学   66   132 - 136   2015.4

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    Language:Japanese  

  • Boron dipyrromethene as a fluorescent caging group for single-photon uncaging with long-wavelength visible light Reviewed Major achievement

    ACS Chemical Biology   9 ( 10 )   2242 - 2246   2014.8( ISSN:1554-8929 )

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  • b-tubulin mutations that cause severe neuropathies disrupt axonal transport Reviewed Major achievement

    EMBO JOURNAL   32 ( 10 )   1352 - 1364   2013.3( ISSN:0261-4189 )

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

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Presentations

  • 高時空間分解能4Dイメージングによる線虫全脳活動計測

    高橋光規

    第129回日本解剖学会総会・全国学術集会  2024.3 

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    Event date: 2024.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:那覇  

  • 高時空間分解能4Dイメージングによる線虫全脳活動の取得

    高橋光規

    第46回日本分子生物学会年会  2023.12 

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    Event date: 2023.12

    Language:Japanese   Presentation type:Poster presentation  

    Venue:神戸  

  • 神経活動イメージング法の開発による感覚処理機構の解明

    高橋光規

    第32回日本バイオイメージング学会学術集会  2023.11 

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    Event date: 2023.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:札幌  

  • 神経活動イメージングのための顕微鏡開発

    高橋光規

    線虫研究の未来を創る会2023  2023.8 

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    Event date: 2023.8

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:神戸  

  • 浸透圧刺激に対する応答多様化機構の解明

    高橋光規

    線虫研究の未来を創る会2023  2023.8 

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    Event date: 2023.8

    Language:Japanese   Presentation type:Poster presentation  

    Venue:神戸  

  • ハイスループットイメージングによる行動多様化機構の解明

    第128回日本解剖学会総会・全国学術集会  2023.3 

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    Event date: 2023.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東北大学川内北キャンパス  

  • High-throughput system for simultaneous monitoring of neural activity and behaviour

    Future of the Nematodes Studies 2022  2022.8 

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    Event date: 2022.8

    Language:English   Presentation type:Poster presentation  

  • Neural and behavioral control by a yellow-light-activatable caged compound

    2021.9 

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    Event date: 2021.9

    Language:English   Presentation type:Oral presentation(general)  

  • Optical control and recording of neuronal activity and behaviour in Caenorhabditis elegans by yellow-light-activatable caged compound Major achievement

    The 126th Annual Meeting of The Japanese Association of Anatomists and the 98th Annual Meeting of The physiological Society of Japan  2021.3 

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    Event date: 2021.3

    Language:English   Presentation type:Poster presentation  

  • 神経細胞無害で活性化 記憶疾患解明、治療に期待 Major achievement

    山梨日日新聞  2021.3 

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    Event date: 2021.3

    Language:Japanese   Presentation type:Media report,etc.  

  • 光子と電子による神経機能と構造の解析

    高橋光規、神谷真子、河谷稔、梅澤啓太郎、浦野泰照、丹羽伸介、小田賢幸

    第125回日本解剖学会総会・全国学術集会  2020.3 

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    Event date: 2020.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:山口県宇部市  

  • Functional and structural approaches by photon and electron in neurobiology of C. elegans

    Hironori Takahashi, Mako Kamiya, Minoru Kawatani, Keitaro Umezawa, Shinsuke Niwa, Yoshiaki Ukita, Yasuteru Urano, Toshiyuki Oda

    Future of the Nematodes Studies  2019.8 

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    Event date: 2019.8

    Language:English   Presentation type:Poster presentation  

  • 新規ケージド化合物による線虫神経活動の光制御

    高橋光規

    第124回日本解剖学会総会・全国学術集会  2019.3  日本解剖学会

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    Event date: 2019.3

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:新潟県新潟市  

  • Optical control of neural activity in C. elegans by novel caged compounds International conference

    Hironori Takahashi

    8th Asia Pacific International Congress of Anatomists  2018.10  Korean Association of Anatomists

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    Event date: 2018.10

    Language:English   Presentation type:Oral presentation(general)  

    Venue:BEXCO, Busan, Korea  

  • Light-induced neural activation and behavioural control by novel caged compounds without inducing light avoidance behaviour

    2018.9 

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    Event date: 2018.9

    Language:English   Presentation type:Oral presentation(general)  

  • 一次繊毛を有する感覚神経の光による活動制御

    高橋光規

    第9回繊毛研究会  2018.6 

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    Event date: 2018.6

    Language:Japanese   Presentation type:Oral presentation(general)  

    Venue:山梨県勝沼市  

  • 線虫神経シナプスの電子顕微鏡観察

    日本解剖学会総会・全国学術集会  2018.3 

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    Event date: 2018.3

    Language:Japanese   Presentation type:Poster presentation  

  • 線虫の電子顕微鏡観察

    第8回繊毛研究会  2017.10 

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    Event date: 2017.10

    Language:Japanese   Presentation type:Oral presentation(general)  

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Industrial Property Rights

  • 切片作成装置および支持部材

    山崎 佳夫、北條 雅史、高橋 光規

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    Applicant:株式会社シンテック、国立大学法人山梨大学

    Application no:2022-084649  Date applied:2022.5

    Country of applicant:Domestic  

Awards

  • 第32回山下太郎学術研究奨励賞

    2021.6   一般財団法人山下太郎顕彰育英会   神経活動を光で制御する全光学神経生理学法の開発

    高橋光規

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    Award type:Award from publisher, newspaper, foundation, etc. 

  • コニカミノルタ画像科学奨励賞

    2020.1   コニカミノルタ科学技術振興財団   神経活動の光制御と行動画像解析を駆使した記憶学習メカニズムの解明

    高橋光規

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    Award type:Award from publisher, newspaper, foundation, etc. 

Teaching Experience (On-campus)

  • 解剖学A

    2023Year  Type of subject:Professional education (undergraduate)

  • 神経科学特論

    2022Year  Type of subject:Dr. (Graduate School)

  • 解剖学B Major achievement

    2022Year  Type of subject:Professional education (undergraduate)

  • 解剖学B Major achievement

    2020Year  Type of subject:Professional education (undergraduate)

  • 神経科学特論 Major achievement

    2020Year  Type of subject:Dr. (Graduate School)

  • 先端脳科学特別教育プログラム

    2019Year  Type of subject:Master's (Graduate School)

  • 解剖学A Major achievement

    2019Year  Type of subject:Professional education (undergraduate)

  • 神経科学特論

    2019Year  Type of subject:Dr. (Graduate School)

  • 先端脳科学特別教育プログラム

    2018Year  Type of subject:Master's (Graduate School)

  • 解剖学B Major achievement

    2018Year  Type of subject:Professional education (undergraduate)

  • 解剖学A Major achievement

    2018Year  Type of subject:Professional education (undergraduate)

  • 神経科学特論

    2018Year  Type of subject:Dr. (Graduate School)

  • 解剖学B Major achievement

    2017Year  Type of subject:Professional education (undergraduate)

  • 解剖学A Major achievement

    2017Year  Type of subject:Professional education (undergraduate)

  • Histology Major achievement

    2016Year  Type of subject:Professional education (undergraduate)

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Other educational achievements

  • CBT試験監督

    2017

Social Activities

  • Future of the Nematodes Studies 2022

    Role(s): Planner, Organizing member

    2022.5 - 2022.8

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    Audience: Graduate students, Researchesrs

    Type:Seminar, workshop

Professional Memberships

  • 日本解剖学会

    2018